Apoptosis in the striatum of rats following intraperitoneal injection of 3-nitropropionic acid

Brain Research

Volumn 745, Issue 1-2, 1997, Pages 343-347

  Sato, Shuzo ^a   Gobbel, Glenn T ^a   Honkaniemi, Jari ^b   Li, Yibing ^a   Kondo, Takeo ^a   Murakami, Kensuke ^a   Sato, Minako ^a   Copin, Jean Christophe ^a   Chan, Pak H ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b SAN FRANCISCO VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

3 Nitropropionic acid; Apoptosis; DNA fragmentation; Huntington's disease; Mitochondria

Indexed keywords

3 NITROPROPIONIC ACID; DNA FRAGMENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; CONTROLLED STUDY; CORPUS STRIATUM; HISTOLOGY; HUNTINGTON CHOREA; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; MITOCHONDRION; NONHUMAN; PRIORITY JOURNAL; RAT; SHORT SURVEY;

EID: 0031023624     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(96)01231-0     Document Type: Article

References (23)

1. Alston, T.A., Mela, L. and Bright, HJ., 3-Nitropropionate, the toxic substance of Indigofera, is a suicide inactivator of succinate dehydrogenase, Proc. Natl. Acad. Sci. USA, 74 (1977) 3767-3771.
2. Ankarcrona, M., Dypbukt, J.M., Bonfoco, E., Zhivotovsky, B., Orrenius, S., Lipton, S.A. and Nicotera, P., Glutamate-induced neuronal death: a succession of necrosis or apoptosis depending on mitochondrial function, Neuron, 15 (1995) 961-973.
3. Beal, M.F., Brouillet, E., Jenkins, B.G., Ferrante, R.J., Kowall, N.W., Miller, J.M., Storey, E., Srivastava, R., Rosen, B.R. and Hyman, B.T., Neurochemical and histologic characterization of striatal excitotoxic lesions produced by the mitochondrial toxin 3-nitropropionic acid, J. Neurosci., 13 (1993) 4181-4192.
4. Beal, M.F., Ferrante, R.J., Henshaw, R., Matthews, R.T., Chan, P.H., Kowall, N.W., Epstein, C.J. and Schulz, J.B., 3-Nitropropionic acid neurotoxicity is attenuated in copper/zinc superoxide dismutase transgenic mice, J. Neurochem., 65 (1995) 919-922.
5. Behrens, M.I., Koh, J., Canzoniero, L.M., Sensi, S.L., Csernansky, C.A. and Choi, D.W., 3-Nitropropionic acid induces apoptosis in cultured striatal and cortical neurons, NeuroReport, 6 (1995) 545-548.
6. Brennan, Jr., W.A., Bird, E.D. and Aprille, J.R., Regional mitochondrial respiratory activity in Huntington's disease brain, J. Neurochem., 44 (1985) 1948-1950.
7. Brouillet, E., Hyman, B.T., Jenkins, B.G., Henshaw, D.R., Schulz, J.B., Sodhi, P., Rosen, B.R. and Beal, M.F., Systemic or local administration of azide produces striatal lesions by an energy impairment-induced excitotoxic mechanism, Exp. Neurol., 129 (1994) 175-182.
8. Coles, C.J., Edmondson, D.E. and Singer, T.P., Inactivation of succinate dehydrogenase by 3-nitropropionate, J. Biol. Chem., 254 (1979) 5161-5167.
9. Copani, A., Bruno, V.M., Barresi, V., Battaglia, G., Condorelli, D.F. and Nicoletti, F., Activation of metabotropic glutamate receptors prevents neuronal apoptosis in culture, J. Neurochem., 64 (1995) 101-108.
10. Gavrieli, Y., Sherman, Y. and Ben-Sasson, S.A., Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation, J. Cell Biol., 119 (1992) 493-501.
11. Gold, R., Schmied, M., Giegerich, G., Breitschopf, H., Hartung, H.P., Toyka, K.V. and Lassmann, H., Differentiation between cellular apoptosis and necrosis by the combined use of in situ tailing and nick translation techniques (see comments), Lab. Invest., 71 (1994) 219-225.
12. Greenlund, L.J., Deckwerth, T.L. and Johnson, Jr., E.M., Superoxide dismutase delays neuronal apoptosis: a role for reactive oxygen species in programmed neuronal death, Neuron, 14 (1995) 303-315.
13. Hamilton, B.F. and Gould, D.H., Nature and distribution of brain lesions in rats intoxicated with 3-nitropropionic acid: a type of hypoxic (energy deficient) brain damage, Acta Neuropathol. (Berl.), 72 (1987) 286-297.
14. Henneberry, R.C., Novelli, A., Vigano, M.A., Reilly, J.A., Cox, J.A. and Lysko, P.G., Energy-related neurotoxicity at the NMDA receptor: a possible role in Alzheimer's disease and related disorders, Prog. Clin. Biol. Res., 317 (1989) 143-156.
15. Ludolph, A.C., Seelig, M., Ludolph, A.G., Sabri, M.I. and Spencer, P.S., ATP deficits and neuronal degeneration induced by 3-nitropropionic acid, Ann. NY Acad. Sci., 648 (1992) 300-302.
16. Mitchell, I.J., Lawson, S., Moser, B., Laidlaw, S.M., Cooper, A.J., Walkinshaw, G. and Waters, C.M., Glutamate-induced apoptosis results in a loss of striatal neurons in the parkinsonian rat, Neuroscience, 63 (1994) 1-5.
17. Palfi, S., Ferrante, R.J., Brouillet, E., Beal, M.F., Dolan, R., Guyot, M.C., Peschanski, M. and Hantraye, P., Chronic 3-nitropropionic acid treatment in baboons replicates the cognitive and motor deficits of Huntington's disease, J. Neurosci., 16 (1996) 3019-3025.
18. Portera-Cailliau, C., Hedreen, J.C., Price, D.L. and Koliatsos, V.E., Evidence for apoptotic cell death in Huntington disease and excitotoxic animal models, J. Neurosci., 15 (1995) 3775-3787.
19. Riepe, M., Hori, N., Ludolph, A.C., Carpenter, D.O., Spencer, P.S. and Allen, C.N., Inhibition of energy metabolism by 3-nitropropionic acid activates ATP-sensitive potassium channels, Brain Res., 586 (1992) 61-66.
20. Villa, P., Miehe, M., Sensenbrenner, M. and Pettmann, B., Synthesis of specific proteins in trophic factor-deprived neurons undergoing apoptosis, J. Neurochem., 62 (1994) 1468-1475.
21. Wijsman, J.H., Jonker, R.R., Keijzer, R., Van de Velde, C.J., Cornelisse, C.J. and Van Dierendonck, J.H., A new method to detect apoptosis in paraffin sections: in situ end-labeling of fragmented DNA, J. Histochem. Cytochem., 41 (1993) 7-12.
22. Wyllie, A.H., Kerr, J.F. and Currie, A.R., Cell death: the significance of apoptosis, Int. Rev. Cytol., 68 (1980) 251-306.
23. Zeevalk, G.D. and Nicklas, W.J., Chemically induced hypoglycemia and anoxia-relationship to glutamate receptor-mediated toxicity in retina, J. Pharmacol. Exp. Ther., 253 (1990) 1285-1292.