Role of blood vessels in producing pathological changes in the brain with Alzheimer's disease

Annals of the New York Academy of Sciences

Volumn 903, Issue , 2000, Pages 46-54

  Miyakawa, Taihei ^a   Kimura, Takemi ^a   Hirata, Shinichi ^a   Fujise, Noboru ^a   Ono, Tsunehiko ^a   Ishizuka, Koko ^a   Nakabayashi, Jun ^a  

^a KUMAMOTO UNIV SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN;

AGED; ALZHEIMER DISEASE; BLOOD BRAIN BARRIER; CLINICAL ARTICLE; CONFERENCE PAPER; CONTROLLED STUDY; ENDOCYTOSIS; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LASER MICROSCOPY; PARENCHYMA; PROTEIN TRANSPORT; SENILE PLAQUE;

EID: 0034019481     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.2000.tb06349.x     Document Type: Conference Paper

References (18)

1. 1. KANG, J. et al. 1987. The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor. Nature 325: 733-736.
2. 2. AMERICAN PSYCHIATRIC ASSOCIATION. 1987. DSM-III-R: Diagnostic and statistical manual of mental disorders, 3rd edit. revised. American Psychiatric Association, Washington, DC.
3. 3. KHACHATURIAN, Z.S. 1985. Diagnosis of Alzheimer's disease. Arch. Neurol. 42: 1097-1105.
4. 4. YAMAGUCHI, H. et al. 1998. Immunohistochemical analysis of COOH-termini of amyloid beta protein (Aβ) using end-specific antisera for Aβ40 and Aβ42 in Alzheimer's disease and normal aging. Amyloid: Int. J. Exp. Clin. Invest. 2: 7-16.
5. 5. SCHOLZ, W. 1938. Studien zur Pathologie der Hirngefasse in Senium. In Proceedings of the Fifth International Congress of Neuropathology, Zurich.: 490-494.
6. 6. KOSAKA, T. 1997. The βAPP717 Alzheimer mutation increases the percentage of plasma amyloid-β protein ending at Aβ42(43). Neurology 48: 741-745.
7. 7. HAASS, C. et al. 1992. Amyloid β-peptide is produced by cultured cells during normal metabolism. Nature 359: 322-325.
8. 8. SEUBERT, P. et al. 1992. Isolation and quantification of soluble Alzheimer's β-peptide from biological fluids. Nature 359: 325-327.
9. 9. MIYAKAWA, T. et al. 1974. Ultrastructure of capillary plaque-like degeneration in senile dementia: Mechanism of amyloid production. Acta Neuropathol. (Berl.) 29: 229-236.
10. 10. MIYAKAWA, T. & Y. UEHARA. 1979. Observations of amyloid angiopathy and senile plaques by the scanning electron microscope. Acta Neuropathol. (Berl.) 48: 153-156.
11. 11. MIYAKAWA, T. et al. 1982. The relationship between senile plaques and cerebral blood vessels in Alzheimer's disease and senile dementia. Morphological mechanism of senile plaque production. Virchows Arch. B Pathol. 40: 121-129.
12. 12. MIYAKAWA, T. et al. 1986. The relationship between amyloid fibrils around cerebral blood vessels and senile plaques, and ultrastructure of amyloid fibrils. In International Symposium on Dementia and Amyloid (Tokyo, Japan). Neuropathology (Suppl. 3): 37-48.
13. 13. MIYAKAWA, T. 1997. Electron microscopy of amyloid fibrils and microvessels. Ann. N.Y. Acad. Sci. 826: 25-34.
14. 14. SUZUKI, N. et al. 1994. An increased percentage of long amyloid β-protein is secreted by familial amyloid β-protein precursor (βAPP717) mutants. Science 264: 1336-1340.
15. 15. MARTEL, C.L. et al. 1996. Blood-brain barrier uptake of the 40 and 42 amino acid sequences of circulating Alzheimer's amyloid β in guinea pigs. Neurosci. Lett. 206: 157-160.
16. 16. DELAÈRE, P. et al. 1991. Subtypes and differential laminar distributions of βA4 deposits in Alzheimer's disease: relationship with the intellectual status of 26 cases. Acta Neuropathol. (Berl.) 81: 328-335.
17. 1-42 levels in cortex correlate with apolipoprotein E epsilon4 allele dosage in sporadic Alzheimer's disease. Brain Res. 748: 250-252.
18. 18. FUNATO, H. et al. 1998. Quantitation of amyloid β-protein in the cortex during aging and in Alzheimer's disease. Am. J. Pathol. 152: 1633-1640.