Hdmx protein stability is regulated by the ubiquitin ligase activity of Mdm2

Journal of Biological Chemistry

Volumn 278, Issue 40, 2003, Pages 38315-38324

  De Graaf, Petra ^c   Little, Natalie A ^c   Ramos, Yolande F M ^c   Meulmeester, Erik ^c   Letteboer, Stef J F ^a   Jochemsen, Aart G ^b  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME KINETICS; GENES; RNA; TUMORS;

TRANSCRIPTIONAL LEVELS;

PROTEINS;

CASPASE 3; GENE PRODUCT; HDMX PROTEIN; MESSENGER RNA; MUTANT PROTEIN; PROTEASOME; PROTEIN MDM2; PROTEIN P53; TUMOR SUPPRESSOR PROTEIN; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG;

ACIDITY; ARTICLE; AUTOREGULATION; CONTROLLED STUDY; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN STABILITY; PROTEIN TARGETING; REGULATORY MECHANISM;

ALTERNATIVE SPLICING; BLOTTING, WESTERN; CASPASE 3; CASPASES; CYCLOHEXIMIDE; EXONS; GENETIC VECTORS; HUMANS; LAC OPERON; LIGASES; LUCIFERASES; MICROSCOPY, FLUORESCENCE; MODELS, GENETIC; NUCLEAR PROTEINS; PLASMIDS; PRECIPITIN TESTS; PROMOTER REGIONS (GENETICS); PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTEIN SYNTHESIS INHIBITORS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-MDM2; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA; RNA, MESSENGER; TIME FACTORS; TRANSCRIPTION, GENETIC; TRANSFECTION; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEIN P53; UBIQUITIN;

EID: 0141866880     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M213034200     Document Type: Article

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