Rescue of embryonic lethality in Mdm4-null mice by loss of Trp53 suggests a nonoverlapping pathway with MDM2 to regulate p53

Nature Genetics

Volumn 29, Issue 1, 2001, Pages 92-95

  Parant, John ^a   Chavez Reyes, Arturo ^a,b   Little, Natalie A ^c   Yan, Wen ^a   Reinke, Valerie ^a   Jochemsen, Aart G ^c   Lozano, Guillermina ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b UNIVERSIDAD AUTÓNOMA DE NUEVO LEÓN   (Mexico)

^c LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

GENE PRODUCT; PROTEIN MDM2; PROTEIN MDMX; PROTEIN P53; PROTEIN TRP53; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG;

ALLELE; ANIMAL CELL; ANIMAL MODEL; APOPTOSIS; ARTICLE; CARCINOGENESIS; CELL CYCLE; CELL DEATH; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; CROSSING OVER; GENE ACTIVATION; GENE CONTROL; GENETIC TRANSCRIPTION; LETHAL GENE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN PROTEIN INTERACTION; TRANSCRIPTION REGULATION;

ANIMALS; BASE SEQUENCE; BLOTTING, WESTERN; DNA PRIMERS; EMBRYO; GENES, LETHAL; GENES, P53; IN SITU NICK-END LABELING; MICE; MICE, KNOCKOUT; NUCLEAR PROTEINS; POLYMERASE CHAIN REACTION; PRECIPITIN TESTS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-MDM2; TUMOR SUPPRESSOR PROTEIN P53;

ANIMALIA;

EID: 0034863683     PISSN: 10614036     EISSN: None     Source Type: Journal    
DOI: 10.1038/ng714     Document Type: Article

References (18)

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