Overexpression of Mdm2 and MdmX fusion proteins alters p53 mediated transactivation, ubiquitination, and degradation

Biochemistry

Volumn 42, Issue 8, 2003, Pages 2291-2299

  Ghosh, Mithua ^a   Huang, Keven ^a   Berberich, Steven J ^a  

^a WRIGHT STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FUSION PROTEINS;

DEGRADATION; FLUORESCENCE; TUMORS;

PROTEINS;

BINDING PROTEIN; CELL PROTEIN; HYBRID PROTEIN; LIGASE; PROTEASOME; PROTEIN MDM2; PROTEIN MDMX; PROTEIN P53; PROTEIN X; REGULATOR PROTEIN; TUMOR SUPPRESSOR PROTEIN; UBIQUITIN; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN;

ANIMAL CELL; ARTICLE; CELL LINE; CHEMICAL REACTION; CONTROLLED STUDY; ENZYME DEGRADATION; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; PROTEIN STRUCTURE; PROTEIN TARGETING; REGULATORY MECHANISM; SEQUENCE HOMOLOGY; TRANSACTIVATION; TRANSCRIPTION REGULATION; UBIQUITINATION; ZINC FINGER MOTIF;

ANIMALS; CELL LINE; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; MICE; NEOPLASM PROTEINS; NUCLEAR PROTEINS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-MDM2; RECOMBINANT FUSION PROTEINS; TRANS-ACTIVATION (GENETICS); TRANSFECTION; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEIN P53; UBIQUITIN;

ANIMALIA;

EID: 0037418564     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi0271291     Document Type: Article

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