메뉴 건너뛰기




Volumn 17, Issue 9, 2003, Pages 1731-1737

Transforming growth factor-β signaling in normal and malignant hematopoiesis

Author keywords

CDK inhibitors; Hematopoiesis; Human T cell lymphotropic virus type I (HTLV I); Leukemogenosis; Smad; TGF receptors; Transforming growth factor (TGF )

Indexed keywords

HYBRID PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; ONCOPROTEIN; PROTEIN ETO; PROTEIN EVI 1; PROTEIN P15; PROTEIN P27; SMAD PROTEIN; TAX PROTEIN; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

EID: 0141613833     PISSN: 08876924     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.leu.2403069     Document Type: Review
Times cited : (116)

References (106)
  • 1
    • 0025222517 scopus 로고
    • The transforming growth factor-β family
    • Massague J. The transforming growth factor-β family. Annu Rev Cell Biol 1990; 6: 597-641.
    • (1990) Annu. Rev. Cell Biol. , vol.6 , pp. 597-641
    • Massague, J.1
  • 3
    • 0029784067 scopus 로고    scopus 로고
    • Transforming growth factor β suppresses genomic instability independent of a G1 arrest, p53, and Rb
    • Glick A, Weinberg W, Wu IH, Quan W, Yuspa SH. Transforming growth factor β suppresses genomic instability independent of a G1 arrest, p53, and Rb. Cancer Res 1996; 56: 3645-3650.
    • (1996) Cancer Res. , vol.56 , pp. 3645-3650
    • Glick, A.1    Weinberg, W.2    Wu, I.H.3    Quan, W.4    Yuspa, S.H.5
  • 4
    • 0032763469 scopus 로고    scopus 로고
    • Specificity, diversity, and regulation in TGF-β superfamily signaling
    • Piek E, Heldin C-H, ten Dijke P. Specificity, diversity, and regulation in TGF-β superfamily signaling. FASEB J 1999; 13: 2105-2124.
    • (1999) FASEB J. , vol.13 , pp. 2105-2124
    • Piek, E.1    Heldin, C.-H.2    ten Dijke, P.3
  • 5
    • 0034574298 scopus 로고    scopus 로고
    • How cells read TGF-β signals
    • Massague J. How cells read TGF-β signals. Nat Rev Mol Cell Biol 2000; 1: 169-178.
    • (2000) Nat. Rev. Mol. Cell Biol. , vol.1 , pp. 169-178
    • Massague, J.1
  • 6
    • 0037204990 scopus 로고    scopus 로고
    • Signal transduction by the TGF-β superfamily
    • Attisano L, Wrana JL. Signal transduction by the TGF-β superfamily. Science 2002; 296: 1646-1647.
    • (2002) Science , vol.296 , pp. 1646-1647
    • Attisano, L.1    Wrana, J.L.2
  • 8
    • 0035835770 scopus 로고    scopus 로고
    • TGF-β signaling and cancer
    • Hata A. TGF-β signaling and cancer. Exp Cell Res 2001; 264: 111-116.
    • (2001) Exp. Cell Res. , vol.264 , pp. 111-116
    • Hata, A.1
  • 9
    • 0033515620 scopus 로고    scopus 로고
    • A Smad transcriptional corepressor
    • Wotton D, Lo RS, Lee S, Massague J. A Smad transcriptional corepressor. Cell 1999; 97: 29-39.
    • (1999) Cell , vol.97 , pp. 29-39
    • Wotton, D.1    Lo, R.S.2    Lee, S.3    Massague, J.4
  • 10
    • 0031587828 scopus 로고    scopus 로고
    • The MAD-related protein Smad7 associates with the TGF-β receptor and functions as an antagonist of TGF-β signaling
    • Hayashi H, Abdollah S, Qiu Y, Cai J, Xu YY, Grinnell BW et al. The MAD-related protein Smad7 associates with the TGF-β receptor and functions as an antagonist of TGF-β signaling. Cell 1997; 89: 1165-1173.
    • (1997) Cell , vol.89 , pp. 1165-1173
    • Hayashi, H.1    Abdollah, S.2    Qiu, Y.3    Cai, J.4    Xu, Y.Y.5    Grinnell, B.W.6
  • 11
    • 0033580393 scopus 로고    scopus 로고
    • Cross-talk between the Smad1 and Ras/MEK signaling pathways for TGF-β
    • Yue J, Frey R, Mulder K. Cross-talk between the Smad1 and Ras/MEK signaling pathways for TGF-β. Oncogene 1999; 18: 2033-2037.
    • (1999) Oncogene , vol.18 , pp. 2033-2037
    • Yue, J.1    Frey, R.2    Mulder, K.3
  • 12
    • 0033605562 scopus 로고    scopus 로고
    • ATF-2 is a common nuclear target of Smad and TAK1 pathways in transforming growth factor-β signaling
    • Sano Y, Harada J, Tashiro S, Gotoh-Mandeville R, Maekawa T, Ishii S. ATF-2 is a common nuclear target of Smad and TAK1 pathways in transforming growth factor-β signaling. J Biol Chem 1999; 274: 8949-8957.
    • (1999) J. Biol. Chem. , vol.274 , pp. 8949-8957
    • Sano, Y.1    Harada, J.2    Tashiro, S.3    Gotoh-Mandeville, R.4    Maekawa, T.5    Ishii, S.6
  • 13
    • 0033106484 scopus 로고    scopus 로고
    • A mechanism of repression of TGFβ/Smad signaling by oncogenic Ras
    • Kretzschmar M, Doody J, Timokhina I, Massague J. A mechanism of repression of TGFβ/Smad signaling by oncogenic Ras. Genes Dev 1999; 13: 804-816.
    • (1999) Genes Dev. , vol.13 , pp. 804-816
    • Kretzschmar, M.1    Doody, J.2    Timokhina, I.3    Massague, J.4
  • 14
    • 0029551805 scopus 로고
    • Identification of a member of the MAPKKK family as a potential mediator of TGF-β signal transduction
    • Yamaguchi K, Shirakabe K, Shibuya H, Irie K, Oishi I, Ueno N et al. Identification of a member of the MAPKKK family as a potential mediator of TGF-β signal transduction. Science 1995; 270: 2008-2011.
    • (1995) Science , vol.270 , pp. 2008-2011
    • Yamaguchi, K.1    Shirakabe, K.2    Shibuya, H.3    Irie, K.4    Oishi, I.5    Ueno, N.6
  • 16
    • 0028937610 scopus 로고
    • Transforming growth factor β activation of p44mapk in proliferating cultures of epithelial cells
    • Hartsough MT, Mulder KM. Transforming growth factor β activation of p44mapk in proliferating cultures of epithelial cells. J Biol Chem 1995; 270: 7117-7124.
    • (1995) J. Biol. Chem. , vol.270 , pp. 7117-7124
    • Hartsough, M.T.1    Mulder, K.M.2
  • 17
    • 15844431960 scopus 로고    scopus 로고
    • A novel kinase cascade mediated by mitogen-activated protein kinase 6 and MKK3
    • Moriguchi T, Kuroyanagi N, Yamaguchi K, Gotoh Y, Irie K, Kano T et al. A novel kinase cascade mediated by mitogen-activated protein kinase 6 and MKK3. J Biol Chem 1996; 271: 13675-13679.
    • (1996) J. Biol. Chem. , vol.271 , pp. 13675-13679
    • Moriguchi, T.1    Kuroyanagi, N.2    Yamaguchi, K.3    Gotoh, Y.4    Irie, K.5    Kano, T.6
  • 18
    • 0032872650 scopus 로고    scopus 로고
    • TGF-β-activating kinase-1 inhibits cell cycle and expression of cyclin D1 and A in LLC-PK1 cells
    • Yoshio T, Nakashima O, Inoshita S, Kuwahara M, Sasaki S, Marumo F. TGF-β-activating kinase-1 inhibits cell cycle and expression of cyclin D1 and A in LLC-PK1 cells. Kidney Int 1999; 56: 1378-1390.
    • (1999) Kidney Int. , vol.56 , pp. 1378-1390
    • Yoshio, T.1    Nakashima, O.2    Inoshita, S.3    Kuwahara, M.4    Sasaki, S.5    Marumo, F.6
  • 19
    • 0032824787 scopus 로고    scopus 로고
    • Regulation of cyclin D1 expression and cell cycle progression by mitogen-activated protein kinase cascade
    • Terada Y, Inoshita S, Nakashima O, Kuwahara M, Sasaki S, Marumo F. Regulation of cyclin D1 expression and cell cycle progression by mitogen-activated protein kinase cascade. Kidney Int 1999; 56: 1258-1261.
    • (1999) Kidney Int. , vol.56 , pp. 1258-1261
    • Terada, Y.1    Inoshita, S.2    Nakashima, O.3    Kuwahara, M.4    Sasaki, S.5    Marumo, F.6
  • 20
    • 0030961008 scopus 로고    scopus 로고
    • Activation of the hematopoietic progenitor kinase-1 (HPK1)-dependent, stress-activated c-Jun N-terminal kinase (JNK) pathway by transforming growth factor β (TGF-β)-activated kinase (TAK1 , a kinase mediator of TGF β signal transduction
    • Wang W, Zhou G, Hu M, Yao Z, Tan T. Activation of the hematopoietic progenitor kinase-1 (HPK1)-dependent, stress-activated c-Jun N-terminal kinase (JNK) pathway by transforming growth factor β (TGF-β)-activated kinase (TAK1), a kinase mediator of TGF β signal transduction. J Biol Chem 1997; 272: 22771-22775.
    • (1997) J. Biol. Chem. , vol.272 , pp. 22771-22775
    • Wang, W.1    Zhou, G.2    Hu, M.3    Yao, Z.4    Tan, T.5
  • 21
    • 0034070464 scopus 로고    scopus 로고
    • Release from quiescence of primitive human hematopoietic stem/progenitor cells by blocking their cell-surface TGF-β type II receptor in a short-term in vitro assay
    • Fortunel N, Hatzfeld J, Kisselev S, Monier MN, Ducos K, Cardoso A et al. Release from quiescence of primitive human hematopoietic stem/progenitor cells by blocking their cell-surface TGF-β type II receptor in a short-term in vitro assay. Stem Cells 2000; 18: 102-111.
    • (2000) Stem Cells , vol.18 , pp. 102-111
    • Fortunel, N.1    Hatzfeld, J.2    Kisselev, S.3    Monier, M.N.4    Ducos, K.5    Cardoso, A.6
  • 22
    • 0034665777 scopus 로고    scopus 로고
    • Transforming growth factor-β: pleiotropic role in the regulation of hematopoiesis
    • Fortunel NO, Hatzfeld A, Hatzfeld JA. Transforming growth factor-β: pleiotropic role in the regulation of hematopoiesis. Blood 2000; 96: 2022-2036.
    • (2000) Blood , vol.96 , pp. 2022-2036
    • Fortunel, N.O.1    Hatzfeld, A.2    Hatzfeld, J.A.3
  • 23
    • 0025159120 scopus 로고
    • Transforming growth factor β directly regulates primitive murine hematopoietic cell proliferation
    • Keller JR, McNiece IK, Sill KT, Ellingsworth LR, Quesenberry PJ, Sing GK et al. Transforming growth factor β directly regulates primitive murine hematopoietic cell proliferation. Blood 1990; 75: 596-602.
    • (1990) Blood , vol.75 , pp. 596-602
    • Keller, J.R.1    McNiece, I.K.2    Sill, K.T.3    Ellingsworth, L.R.4    Quesenberry, P.J.5    Sing, G.K.6
  • 24
    • 9044237272 scopus 로고    scopus 로고
    • Maintenance of murine long-term repopulating stem cells in ex vivo culture is affected by modulation of transforming growth factor-β but not macrophage inflammatory protein-1α activities
    • Soma T, Yu JM, Dunbar CE. Maintenance of murine long-term repopulating stem cells in ex vivo culture is affected by modulation of transforming growth factor-β but not macrophage inflammatory protein-1α activities. Blood 1996; 87: 4561-4567.
    • (1996) Blood , vol.87 , pp. 4561-4567
    • Soma, T.1    Yu, J.M.2    Dunbar, C.E.3
  • 25
    • 0025915706 scopus 로고
    • Stimulation of granulopoiesis by transforming growth factor β: Synergy with granulocyte/macrophage-colony-stimulating factor
    • Keller JR, Jacobsen SE, Sill KT, Ellingsworth LR, Ruscetti FW. Stimulation of granulopoiesis by transforming growth factor β: synergy with granulocyte/macrophage-colony-stimulating factor. Proc Natl Acad Sci USA 1991; 88: 7190-7194.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 7190-7194
    • Keller, J.R.1    Jacobsen, S.E.2    Sill, K.T.3    Ellingsworth, L.R.4    Ruscetti, F.W.5
  • 26
    • 0025803697 scopus 로고
    • Transforming growth factor β trans-modulates the expression of colony stimulating factor receptors on murine hematopoietic progenitor cell lines
    • Jacobsen SE, Ruscetti FW, Dubois CM, Lee J, Boone TC, Keller JR. Transforming growth factor β trans-modulates the expression of colony stimulating factor receptors on murine hematopoietic progenitor cell lines. Blood 1991; 77: 1706-1716.
    • (1991) Blood , vol.77 , pp. 1706-1716
    • Jacobsen, S.E.1    Ruscetti, F.W.2    Dubois, C.M.3    Lee, J.4    Boone, T.C.5    Keller, J.R.6
  • 27
    • 0032846149 scopus 로고    scopus 로고
    • Modification of expression of stem cell factor by various cytokines
    • Sugimoto Y, Koji T, Miyoshi S. Modification of expression of stem cell factor by various cytokines. J Cell Physiol 1999; 181: 285-294.
    • (1999) J. Cell Physiol. , vol.181 , pp. 285-294
    • Sugimoto, Y.1    Koji, T.2    Miyoshi, S.3
  • 28
    • 0028982214 scopus 로고
    • Early CD34high cells can be separated into KIThigh cells in which transforming growth factor-beta (TGF-β) downmodulates c-kit and KITlow cells in which anti-TGF-β upmodulates c-kit
    • Sansilvestri P, Cardoso AA, Batard P, Panterne B, Hatzfeld A, Lim B et al. Early CD34high cells can be separated into KIThigh cells in which transforming growth factor-beta (TGF-β) downmodulates c-kit and KITlow cells in which anti-TGF-β upmodulates c-kit. Blood 1995; 86: 1729-1735.
    • (1995) Blood , vol.86 , pp. 1729-1735
    • Sansilvestri, P.1    Cardoso, A.A.2    Batard, P.3    Panterne, B.4    Hatzfeld, A.5    Lim, B.6
  • 29
    • 0028952955 scopus 로고
    • Transforming growth factor β1 inhibits expression of the gene products for steel factor and its receptor (c-kit)
    • Heinrich MC, Dooley DC, Keeble WW. Transforming growth factor β1 inhibits expression of the gene products for steel factor and its receptor (c-kit). Blood 1995; 85: 1769-1780.
    • (1995) Blood , vol.85 , pp. 1769-1780
    • Heinrich, M.C.1    Dooley, D.C.2    Keeble, W.W.3
  • 30
    • 0028177911 scopus 로고
    • Transforming growth factor-β regulates c-kit message stability and cell-surface protein expression in hematopoietic progenitors
    • Dubois CM, Ruscetti FW, Stankova J, Keller JR. Transforming growth factor-β regulates c-kit message stability and cell-surface protein expression in hematopoietic progenitors. Blood 1994; 83: 3138-3145.
    • (1994) Blood , vol.83 , pp. 3138-3145
    • Dubois, C.M.1    Ruscetti, F.W.2    Stankova, J.3    Keller, J.R.4
  • 31
    • 0025940505 scopus 로고
    • Release of early human hematopoietic progenitors from quiescence by antisense transforming growth factor beta 1 or Rb oligonucleoticles
    • Hatzfeld J, Li ML, Brown EL, Sookdeo H, Levesque JP, O'Toole T et al. Release of early human hematopoietic progenitors from quiescence by antisense transforming growth factor beta 1 or Rb oligonucleoticles. J Exp Med 1991; 174: 925-929.
    • (1991) J. Exp. Med. , vol.174 , pp. 925-929
    • Hatzfeld, J.1    Li, M.L.2    Brown, E.L.3    Sookdeo, H.4    Levesque, J.P.5    O'Toole, T.6
  • 32
    • 0028953810 scopus 로고
    • Transforming growth factor-β and cell cycle regulation
    • Alexandrow MG, Moses HL. Transforming growth factor-β and cell cycle regulation. Cancer Res 1995; 55: 1452-1457.
    • (1995) Cancer Res. , vol.55 , pp. 1452-1457
    • Alexandrow, M.G.1    Moses, H.L.2
  • 33
    • 0027374766 scopus 로고
    • TGF β inhibition of Cdk4 synthesis is linked to cell cycle arrest
    • Ewen ME, Sluss HK, Whitehouse LL, Livingston DM. TGF β inhibition of Cdk4 synthesis is linked to cell cycle arrest. Cell 1993; 74: 1009-1020.
    • (1993) Cell , vol.74 , pp. 1009-1020
    • Ewen, M.E.1    Sluss, H.K.2    Whitehouse, L.L.3    Livingston, D.M.4
  • 34
    • 0027486303 scopus 로고
    • Transforming growth factor β effects on expression of G1 cyclins and cyclin-dependent protein kinases
    • Geng Y, Weinberg RA. Transforming growth factor β effects on expression of G1 cyclins and cyclin-dependent protein kinases. Proc Natl Acad Sci USA 1993; 90: 10315-10319.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 10315-10319
    • Geng, Y.1    Weinberg, R.A.2
  • 35
    • 0030978315 scopus 로고    scopus 로고
    • Repression of the CDK activator Cdc25A and cellcycle arrest by cytokine TGF-β in cells lacking the CDK inhibitor p15
    • Iavarone A, Massague J. Repression of the CDK activator Cdc25A and cellcycle arrest by cytokine TGF-β in cells lacking the CDK inhibitor p15. Nature 1997; 387: 417-422.
    • (1997) Nature , vol.387 , pp. 417-422
    • Iavarone, A.1    Massague, J.2
  • 36
    • 0028168242 scopus 로고
    • p15INK4B is a potential effector of TGF-β-induced cell cycle arrest
    • Hannon GJ, Beach D. p15INK4B is a potential effector of TGF-β-induced cell cycle arrest. Nature 1994; 371: 257-261.
    • (1994) Nature , vol.371 , pp. 257-261
    • Hannon, G.J.1    Beach, D.2
  • 38
    • 0030974040 scopus 로고    scopus 로고
    • Transforming growth factor β stabilizes p15INK4B protein, increases p15INK4B-cdk4 complexes, and inhibits cyclin D1-cdk4 association in human mammary epithelial cells
    • Sandhu C, Garbe J, Bhattacharya N, Daksis J, Pan CH, Yaswen P et al. Transforming growth factor β stabilizes p15INK4B protein, increases p15INK4B-cdk4 complexes, and inhibits cyclin D1-cdk4 association in human mammary epithelial cells. Mol Cell Biol 1997; 17: 2458-2467.
    • (1997) Mol. Cell Biol. , vol.17 , pp. 2458-2467
    • Sandhu, C.1    Garbe, J.2    Bhattacharya, N.3    Daksis, J.4    Pan, C.H.5    Yaswen, P.6
  • 39
    • 0029153609 scopus 로고
    • Kip/Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-β
    • Reynisdottir I, Polyak K, Iavarone A, Massague J. Kip/Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-β. Genes Dev 1995; 9: 1831-1845.
    • (1995) Genes Dev. , vol.9 , pp. 1831-1845
    • Reynisdottir, I.1    Polyak, K.2    Iavarone, A.3    Massague, J.4
  • 40
    • 0032803878 scopus 로고    scopus 로고
    • Myc downregulation by transforming growth factor β required for activation of the p15(Ink4b) G(1) arrest pathway
    • Warner BJ, Blain SW, Seoane J, Massague J. Myc downregulation by transforming growth factor β required for activation of the p15(Ink4b) G(1) arrest pathway. Mol Cell Biol 1999; 19: 5913-5922.
    • (1999) Mol. Cell Biol. , vol.19 , pp. 5913-5922
    • Warner, B.J.1    Blain, S.W.2    Seoane, J.3    Massague, J.4
  • 41
    • 0029073142 scopus 로고
    • Transforming growth factor β induces the cyclin-dependent kinase inhibitor p21 through a p53-independent mechanism
    • Datto MB, Li Y, Panus JF, Howe DJ, Xiong Y, Wang XF. Transforming growth factor β induces the cyclin-dependent kinase inhibitor p21 through a p53-independent mechanism. Proc Natl Acad Sci USA 1995; 92: 5545-5549.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 5545-5549
    • Datto, M.B.1    Li, Y.2    Panus, J.F.3    Howe, D.J.4    Xiong, Y.5    Wang, X.F.6
  • 42
    • 0030907073 scopus 로고    scopus 로고
    • Modifications of p53 protein and accumulation of p21 and gadd45 mRNA in TCF-β1 growth inhibited cells
    • Landesman Y, Bringold F, Milne DD, Meek DW. Modifications of p53 protein and accumulation of p21 and gadd45 mRNA in TCF-β1 growth inhibited cells. Cell Signal 1997; 9: 291-298.
    • (1997) Cell Signal , vol.9 , pp. 291-298
    • Landesman, Y.1    Bringold, F.2    Milne, D.D.3    Meek, D.W.4
  • 43
    • 0032577204 scopus 로고    scopus 로고
    • Transforming growth factor-β1 stimulates or inhibits cell growth via down- or upregulation of p21/Waf1
    • Miyazaki M, Ohashi R, Tsuji T, Mihara K, Gohda E, Namba M. Transforming growth factor-β1 stimulates or inhibits cell growth via down- or upregulation of p21/Waf1. Biochem Biophys Res Commun 1998; 246: 873-880.
    • (1998) Biochem. Biophys. Res. Commun. , vol.246 , pp. 873-880
    • Miyazaki, M.1    Ohashi, R.2    Tsuji, T.3    Mihara, K.4    Gohda, E.5    Namba, M.6
  • 44
    • 0034040637 scopus 로고    scopus 로고
    • p21(cip1) mRNA is controlled by endogenous transforming growth factor-β1 in quiescent human hematopoietic stem/progenitor cells
    • Ducos K, Panterne B, Fortunel N, Hatzfeld A, Monier MN, Hatzfeld J. p21(cip1) mRNA is controlled by endogenous transforming growth factor-β1 in quiescent human hematopoietic stem/progenitor cells. J Cell Physiol 2000; 184: 80-85.
    • (2000) J. Cell Physiol. , vol.184 , pp. 80-85
    • Ducos, K.1    Panterne, B.2    Fortunel, N.3    Hatzfeld, A.4    Monier, M.N.5    Hatzfeld, J.6
  • 45
    • 0034662959 scopus 로고    scopus 로고
    • A role for transcriptional repression of p21CIP1 by c-Myc in overcoming transforming growth factor β-induced cell-cycle arrest
    • Claassen GF, Hann SR. A role for transcriptional repression of p21CIP1 by c-Myc in overcoming transforming growth factor β-induced cell-cycle arrest. Proc Natl Acad Sci USA 2000; 97: 9498-9503.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 9498-9503
    • Claassen, G.F.1    Hann, S.R.2
  • 46
    • 0028179669 scopus 로고
    • p27Kip1 a, cyclin-Cdk inhibitor, links transforming growth factor-β and contact inhibition to cell cycle arrest
    • Polyak K, Kato JY, Solomon MJ, Sherr CJ, Massague J, Roberts JM et al. p27Kip1 a, cyclin-Cdk inhibitor, links transforming growth factor-β and contact inhibition to cell cycle arrest. Genes Dev 1994; 8: 9-22.
    • (1994) Genes Dev. , vol.8 , pp. 9-22
    • Polyak, K.1    Kato, J.Y.2    Solomon, M.J.3    Sherr, C.J.4    Massague, J.5    Roberts, J.M.6
  • 47
    • 0034099227 scopus 로고    scopus 로고
    • Transforming growth factor β(1) selectively inhibits the cyclic AMP-dependent proliferation of primary thyroid epithelial cells by preventing the association of cyclin D3-cdk4 with nuclear p27(kip1)
    • Depoortere F, Pirson I, Bartek J, Dumont JE, Roger PP. Transforming growth factor β(1) selectively inhibits the cyclic AMP-dependent proliferation of primary thyroid epithelial cells by preventing the association of cyclin D3-cdk4 with nuclear p27(kip1). Mol Biol Cell 2000; 11: 1061-1076.
    • (2000) Mol. Biol. Cell , vol.11 , pp. 1061-1076
    • Depoortere, F.1    Pirson, I.2    Bartek, J.3    Dumont, J.E.4    Roger, P.P.5
  • 48
    • 0034657830 scopus 로고    scopus 로고
    • Modulation of bcl-2 and p27 in human primitive proliferating hematopoietic progenitors by autocrine TGF β1 is a cell cycle-independent effect and influences their hematopoietic potential
    • Pierelli L, Marone M, Bonanno G, Mozzetti S, Rutella S, Morosetti R et al. Modulation of bcl-2 and p27 in human primitive proliferating hematopoietic progenitors by autocrine TGF β1 is a cell cycle-independent effect and influences their hematopoietic potential. Blood 2000; 95: 3001-3009.
    • (2000) Blood , vol.95 , pp. 3001-3009
    • Pierelli, L.1    Marone, M.2    Bonanno, G.3    Mozzetti, S.4    Rutella, S.5    Morosetti, R.6
  • 49
    • 0037079726 scopus 로고    scopus 로고
    • Molecular mechanism of transforming growth factor β-mediated cell-cycle modulation in primary human CD34(+) progenitors
    • Dao MA, Hwa J, Nolta JA. Molecular mechanism of transforming growth factor β-mediated cell-cycle modulation in primary human CD34(+) progenitors. Blood 2002; 99: 499-506.
    • (2002) Blood , vol.99 , pp. 499-506
    • Dao, M.A.1    Hwa, J.2    Nolta, J.A.3
  • 50
    • 0034040637 scopus 로고    scopus 로고
    • p21(cip1) mRNA is controlled by endogenous transforming growth factor-β1 in quiescent human hematopoietic stem/progenitor cells
    • Ducos K, Panterne B, Fortunel N, Hatzfeld A, Monier MN, Hatzfeld J. p21(cip1) mRNA is controlled by endogenous transforming growth factor-β1 in quiescent human hematopoietic stem/progenitor cells. J Cell Physiol 2000; 184: 80-85.
    • (2000) J. Cell Physiol. , vol.184 , pp. 80-85
    • Ducos, K.1    Panterne, B.2    Fortunel, N.3    Hatzfeld, A.4    Monier, M.N.5    Hatzfeld, J.6
  • 51
    • 0032573177 scopus 로고    scopus 로고
    • Reduction in levels of the cyclin-dependent kinase inhibitor p27(kip-1) coupled with transforming growth factor β neutralization induces cell-cycle entry and increases retroviral transduction of primitive human hematopoietic cells
    • Dao MA, Taylor N, Nolta JA. Reduction in levels of the cyclin-dependent kinase inhibitor p27(kip-1) coupled with transforming growth factor β neutralization induces cell-cycle entry and increases retroviral transduction of primitive human hematopoietic cells. Proc Natl Acad Sci USA 1998; 95: 13006-13011.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 13006-13011
    • Dao, M.A.1    Taylor, N.2    Nolta, J.A.3
  • 52
    • 0035895046 scopus 로고    scopus 로고
    • Transforming growth factor-β1 mediates cell-cycle arrest of primitive hematopoietic cells independent of p21Cip1/Waf1 or p27Kip1
    • Cheng T, Shen H, Rodrigues N, Stier S, Scadden DT. Transforming growth factor-β1 mediates cell-cycle arrest of primitive hematopoietic cells independent of p21Cip1/Waf1 or p27Kip1. Blood 2001; 98: 3643-3649.
    • (2001) Blood , vol.98 , pp. 3643-3649
    • Cheng, T.1    Shen, H.2    Rodrigues, N.3    Stier, S.4    Scadden, D.T.5
  • 53
    • 0033996341 scopus 로고    scopus 로고
    • TGF-β1 maintains hematopoietic immaturity by a reversible negative control of cell cycle and induces CD34 antigen up-modulation
    • Batard P, Monier MN, Fortunel N, Ducos K, Sansilvestri-Morel P, Phan T et al. TGF-β1 maintains hematopoietic immaturity by a reversible negative control of cell cycle and induces CD34 antigen up-modulation. J Cell Sci 2000; 113: 383-390.
    • (2000) J. Cell Sci. , vol.113 , pp. 383-390
    • Batard, P.1    Monier, M.N.2    Fortunel, N.3    Ducos, K.4    Sansilvestri-Morel, P.5    Phan, T.6
  • 54
    • 0036153438 scopus 로고    scopus 로고
    • Transforming growth factor-β1 transcriptionally activates CD34 and prevents induced differentiation of TF-1 cells in the absence of any cell-cycle effects
    • Marone M, Scambia G, Bonanno G, Rutella S, de Ritis D, Guidi F et al. Transforming growth factor-β1 transcriptionally activates CD34 and prevents induced differentiation of TF-1 cells in the absence of any cell-cycle effects. Leukemia 2002; 16: 94-105.
    • (2002) Leukemia , vol.16 , pp. 94-105
    • Marone, M.1    Scambia, G.2    Bonanno, G.3    Rutella, S.4    de Ritis, D.5    Guidi, F.6
  • 55
    • 0027531528 scopus 로고
    • Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death
    • Kulkarni AB, Huh CG, Becker D, Geiser A, Lyght M, Flanders KC et al. Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death. Proc Natl Acad Sci USA 1993; 90: 770-774.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 770-774
    • Kulkarni, A.B.1    Huh, C.G.2    Becker, D.3    Geiser, A.4    Lyght, M.5    Flanders, K.C.6
  • 56
    • 0026799402 scopus 로고
    • Targeted disruption of the mouse transforming growth factor-β1 gene results in multifocal inflammatory disease
    • Shull MM, Ormsby I, Kier AB, Pawlowski S, Diebold RJ, Yin M et al. Targeted disruption of the mouse transforming growth factor-β1 gene results in multifocal inflammatory disease. Nature 1992; 359: 693-699.
    • (1992) Nature , vol.359 , pp. 693-699
    • Shull, M.M.1    Ormsby, I.2    Kier, A.B.3    Pawlowski, S.4    Diebold, R.J.5    Yin, M.6
  • 57
    • 0036786468 scopus 로고    scopus 로고
    • Reconstitution of lethally irradiated adult mice with dominant negative TGF-β type II receptor-transduced bone marrow leads to myeloid expansion and inflammatory disease
    • Shah AH, Tabayoyong WB, Kimm SY, Kim SJ, Van Parijs L, Lee C. Reconstitution of lethally irradiated adult mice with dominant negative TGF-β type II receptor-transduced bone marrow leads to myeloid expansion and inflammatory disease. J Immunol 2002; 169: 3485-3491.
    • (2002) J. Immunol. , vol.169 , pp. 3485-3491
    • Shah, A.H.1    Tabayoyong, W.B.2    Kimm, S.Y.3    Kim, S.J.4    Van Parijs, L.5    Lee, C.6
  • 58
    • 0037100520 scopus 로고    scopus 로고
    • Induced disruption of the transforming growth factor beta type II receptor gene in mice causes a lethal inflammatory disorder that is transplantable
    • Leveen P, Larsson J, Ehinger M, Cilio CM, Sundler M, Sjostrand LJ et al. Induced disruption of the transforming growth factor beta type II receptor gene in mice causes a lethal inflammatory disorder that is transplantable. Blood 2002; 100: 560-568.
    • (2002) Blood , vol.100 , pp. 560-568
    • Leveen, P.1    Larsson, J.2    Ehinger, M.3    Cilio, C.M.4    Sundler, M.5    Sjostrand, L.J.6
  • 59
    • 0034600070 scopus 로고    scopus 로고
    • Disruption of T cell homeostasis in mice expressing a T cell-specific dominant negative transforming growth factor β II receptor
    • Lucas PJ, Kim SJ, Melby SJ, Gress RE. Disruption of T cell homeostasis in mice expressing a T cell-specific dominant negative transforming growth factor β II receptor. J Exp Med 2000; 191: 1187-1196.
    • (2000) J. Exp. Med. , vol.191 , pp. 1187-1196
    • Lucas, P.J.1    Kim, S.J.2    Melby, S.J.3    Gress, R.E.4
  • 60
    • 0034131557 scopus 로고    scopus 로고
    • Abrogation of TGF-β signaling in T cells leads to spontaneous T cell differentiation and autoimmune disease
    • Gorelik L, Flavell RA. Abrogation of TGF-β signaling in T cells leads to spontaneous T cell differentiation and autoimmune disease. Immunity 2000; 12: 171-181.
    • (2000) Immunity , vol.12 , pp. 171-181
    • Gorelik, L.1    Flavell, R.A.2
  • 61
    • 0025239444 scopus 로고
    • Latent form of transforming growthfactor-β1 acts as a potent growth inhibitor of a human erythroleukemia cell line
    • Piao YF, Ychijo H, Miyagawa K, Ohashi H, Takaku F, Miyazono K. Latent form of transforming growthfactor-β1 acts as a potent growth inhibitor of a human erythroleukemia cell line. Biochem Biophys Res Commun 1990; 167: 27-32.
    • (1990) Biochem. Biophys. Res. Commun. , vol.167 , pp. 27-32
    • Piao, Y.F.1    Ychijo, H.2    Miyagawa, K.3    Ohashi, H.4    Takaku, F.5    Miyazono, K.6
  • 62
    • 0024455089 scopus 로고
    • Effect of transforming growthfactor-β1 on proliferation and induction of hemoglobin accumulation in K-562 cells
    • Chen LL, Dean A, Jenkinson T, Mendelson J. Effect of transforming growthfactor-β1 on proliferation and induction of hemoglobin accumulation in K-562 cells. Blood 1989; 74: 2368-2375.
    • (1989) Blood , vol.74 , pp. 2368-2375
    • Chen, L.L.1    Dean, A.2    Jenkinson, T.3    Mendelson, J.4
  • 63
    • 0026338986 scopus 로고
    • Differential effects of transforming growthfactor-β1 on the proliferation of human lymphoid and myeloid leukemia cells
    • Piacibello W, Severino A, Stacchini A, Aglietta M. Differential effects of transforming growthfactor-β1 on the proliferation of human lymphoid and myeloid leukemia cells. Haematologica 1991; 76: 460-466.
    • (1991) Haematologica , vol.76 , pp. 460-466
    • Piacibello, W.1    Severino, A.2    Stacchini, A.3    Aglietta, M.4
  • 64
    • 0032878291 scopus 로고    scopus 로고
    • A deletion in the gene for transforming growth factor β type I receptor abolishes growth regulation by transforming growth factor beta in cutaneous T cell lymphoma
    • Schieman WP, Pfeifer WM, Levi E, Kadin ME, Lodish HF. A deletion in the gene for transforming growth factor β type I receptor abolishes growth regulation by transforming growth factor beta in cutaneous T cell lymphoma. Blood 1999; 94: 2854-2861.
    • (1999) Blood , vol.94 , pp. 2854-2861
    • Schieman, W.P.1    Pfeifer, W.M.2    Levi, E.3    Kadin, M.E.4    Lodish, H.F.5
  • 65
    • 0029938791 scopus 로고    scopus 로고
    • A dominant inhibitory mutant of the type II transforming growth factor β receptor in the malignant progression of a cutaneous T cell lymphoma
    • Knaus PI, Lindemann D, DeCoteau JF, Perlman R, Yankelev H, Hille M et al. A dominant inhibitory mutant of the type II transforming growth factor β receptor in the malignant progression of a cutaneous T cell lymphoma. Mol Cell Biol 1996; 16: 3480-3489.
    • (1996) Mol. Cell Biol. , vol.16 , pp. 3480-3489
    • Knaus, P.I.1    Lindemann, D.2    DeCoteau, J.F.3    Perlman, R.4    Yankelev, H.5    Hille, M.6
  • 66
    • 0033625354 scopus 로고    scopus 로고
    • Resistance to TGF-β1 correlates with a reduction of TGF-β type II receptor expression in Burkitt's lymphoma and Epstein-Barr virus-transformed B lymphoblastoid cell lines
    • Inman GJ, Allday, MJ. Resistance to TGF-β1 correlates with a reduction of TGF-β type II receptor expression in Burkitt's lymphoma and Epstein-Barr virus-transformed B lymphoblastoid cell lines. J Gen Virol 2000; 81: 1567-1578.
    • (2000) J. Gen. Virol. , vol.81 , pp. 1567-1578
    • Inman, G.J.1    Allday, M.J.2
  • 67
    • 0037212047 scopus 로고    scopus 로고
    • Microsatellite mutations of transforming growth factor-β receptor type II and caspase-5 occur in human precursor T-cell lymphoblastic lymphomas/leukemias in vivo but are not associated with hMSH2 or hMLH1 promoter methylation
    • Scott S, Kimura T, Ichinohasama R, Bergen S, Magliocco A, Reimer C et al. Microsatellite mutations of transforming growth factor-β receptor type II and caspase-5 occur in human precursor T-cell lymphoblastic lymphomas/leukemias in vivo but are not associated with hMSH2 or hMLH1 promoter methylation. Leukemia Res 2003; 27: 23-34.
    • (2003) Leukemia Res. , vol.27 , pp. 23-34
    • Scott, S.1    Kimura, T.2    Ichinohasama, R.3    Bergen, S.4    Magliocco, A.5    Reimer, C.6
  • 68
    • 2642636861 scopus 로고    scopus 로고
    • Microsatellite instability and frameshift mutations in BAX and transforming growth factor-β RII genes are very uncommon in acute lymphoblastic leukemia in vivo but not in cell lines
    • Molenaar JJ, Gerard B, Chambon-Pautas C, Cave H, Duval M, Vilmer E et al. Microsatellite instability and frameshift mutations in BAX and transforming growth factor-β RII genes are very uncommon in acute lymphoblastic leukemia in vivo but not in cell lines. Blood 1998; 92: 230-233.
    • (1998) Blood , vol.92 , pp. 230-233
    • Molenaar, J.J.1    Gerard, B.2    Chambon-Pautas, C.3    Cave, H.4    Duval, M.5    Vilmer, E.6
  • 69
    • 0032915794 scopus 로고    scopus 로고
    • The TGF-β type II receptor in chronic myeloid leukemia: Analysis of microsatellite regions and gene expression
    • Rooke HM, Vitas MR, Crosier PS, Crosier KE. The TGF-β type II receptor in chronic myeloid leukemia: analysis of microsatellite regions and gene expression. Leukemia 1999; 13: 535-541.
    • (1999) Leukemia , vol.13 , pp. 535-541
    • Rooke, H.M.1    Vitas, M.R.2    Crosier, P.S.3    Crosier, K.E.4
  • 70
    • 0035804227 scopus 로고    scopus 로고
    • Mutations of the Smad4 gene in acute myelogeneous leukemia and their functional implications in leukemogenesis
    • Imai Y, Kurokawa M, Izutsu K, Hangaishi A, Maki K, Ogawa S et al. Mutations of the Smad4 gene in acute myelogeneous leukemia and their functional implications in leukemogenesis. Oncogene 2001; 20: 88-96.
    • (2001) Oncogene , vol.20 , pp. 88-96
    • Imai, Y.1    Kurokawa, M.2    Izutsu, K.3    Hangaishi, A.4    Maki, K.5    Ogawa, S.6
  • 71
    • 0032076229 scopus 로고    scopus 로고
    • Conjunction dysfunction: CBP/p300 in human disease
    • Giles RH, Peters DJ, Breuning MH. Conjunction dysfunction: CBP/p300 in human disease. Trends Genet 1998; 14: 178-183.
    • (1998) Trends Genet. , vol.14 , pp. 178-183
    • Giles, R.H.1    Peters, D.J.2    Breuning, M.H.3
  • 72
    • 0030061554 scopus 로고    scopus 로고
    • AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis
    • Okuda T, van Deursen J, Hiebert SW, Grosveld G, Downing JR. AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis. Cell 1996; 84: 321-330.
    • (1996) Cell , vol.84 , pp. 321-330
    • Okuda, T.1    van Deursen, J.2    Hiebert, S.W.3    Grosveld, G.4    Downing, J.R.5
  • 73
    • 0031025416 scopus 로고    scopus 로고
    • Embryonic lethality and impairment of haematopoiesis in mice heterozygous for an AML1-ETO fusion gene
    • Yergeau DA, Hetherington CJ, Wang Q, Zhang P, Sharpe AH, Binder M et al. Embryonic lethality and impairment of haematopoiesis in mice heterozygous for an AML1-ETO fusion gene. Nat Genet 1997; 15: 303-306.
    • (1997) Nat. Genet. , vol.15 , pp. 303-306
    • Yergeau, D.A.1    Hetherington, C.J.2    Wang, Q.3    Zhang, P.4    Sharpe, A.H.5    Binder, M.6
  • 74
    • 0034704128 scopus 로고    scopus 로고
    • Inhibition of the transforming growth factor β1 signaling pathway by the AML1/ETO leukemia-associated fusion protein
    • Jakubowiak A, Pouponnot C, Berguido F, Frank R, Mao S, Massague J et al. Inhibition of the transforming growth factor β1 signaling pathway by the AML1/ETO leukemia-associated fusion protein. J Biol Chem 2000; 275: 40282-40287.
    • (2000) J. Biol. Chem. , vol.275 , pp. 40282-40287
    • Jakubowiak, A.1    Pouponnot, C.2    Berguido, F.3    Frank, R.4    Mao, S.5    Massague, J.6
  • 75
    • 0031883569 scopus 로고    scopus 로고
    • The AML1-MTG8 leukemic fusion protein forms a complex with a novel member of the MTG8(ETO/CDR) family, MTGR1
    • Kitabayashi I, Ida K, Morohoshi F, Yokoyama A, Mitsuhashi N, Shimizu K et al. The AML1-MTG8 leukemic fusion protein forms a complex with a novel member of the MTG8(ETO/CDR) family, MTGR1. Mol Cell Biol 1998; 18: 846-858.
    • (1998) Mol. Cell Biol. , vol.18 , pp. 846-858
    • Kitabayashi, I.1    Ida, K.2    Morohoshi, F.3    Yokoyama, A.4    Mitsuhashi, N.5    Shimizu, K.6
  • 76
    • 0035353203 scopus 로고    scopus 로고
    • The corepressor CtBP interacts with Evi-1 to repress transforming growth factor β signaling
    • Izutsu K, Kurokawa M, Imai Y, Maki K, Mitani K, Hirai H. The corepressor CtBP interacts with Evi-1 to repress transforming growth factor β signaling. Blood 2001; 97: 2815-2822.
    • (2001) Blood , vol.97 , pp. 2815-2822
    • Izutsu, K.1    Kurokawa, M.2    Imai, Y.3    Maki, K.4    Mitani, K.5    Hirai, H.6
  • 78
    • 0031450875 scopus 로고    scopus 로고
    • The EVI1 gene in myeloid leukemia
    • Nucifora G. The EVI1 gene in myeloid leukemia. Leukemia 1997; 11: 2022-2031.
    • (1997) Leukemia , vol.11 , pp. 2022-2031
    • Nucifora, G.1
  • 79
    • 0032400836 scopus 로고    scopus 로고
    • The t(3; 21) fusion product, AML1/Evi-1, interacts with Smad3 and blocks transforming growth factor-β-mediated growth inhibition of myeloid cells
    • Kurokawa M, Mitani K, Imai Y, Ogawa S, Yazaki Y, Hirai H. The t(3; 21) fusion product, AML1/Evi-1, interacts with Smad3 and blocks transforming growth factor-β-mediated growth inhibition of myeloid cells. Blood 1998; 92: 4003-4012.
    • (1998) Blood , vol.92 , pp. 4003-4012
    • Kurokawa, M.1    Mitani, K.2    Imai, Y.3    Ogawa, S.4    Yazaki, Y.5    Hirai, H.6
  • 80
  • 82
    • 0034644472 scopus 로고    scopus 로고
    • TGF-β signaling in growth control, cancer, and heritable disorders
    • Massagué J, Blain SW, Lo RS. TGF-β signaling in growth control, cancer, and heritable disorders. Cell 2000; 103: 295-309.
    • (2000) Cell , vol.103 , pp. 295-309
    • Massagué, J.1    Blain, S.W.2    Lo, R.S.3
  • 83
    • 0025348820 scopus 로고
    • TGF-β1 inhibition of c-myc transcription and growth in keratinocytes is abrogated by viral transforming proteins with pRB binding domains
    • Pietenpol JA, Stein RW, Moran E, Yaciuk P, Schlegel R, Lyons RM et al. TGF-β1 inhibition of c-myc transcription and growth in keratinocytes is abrogated by viral transforming proteins with pRB binding domains. Cell 1990; 61: 777-785.
    • (1990) Cell , vol.61 , pp. 777-785
    • Pietenpol, J.A.1    Stein, R.W.2    Moran, E.3    Yaciuk, P.4    Schlegel, R.5    Lyons, R.M.6
  • 84
  • 85
  • 86
    • 0037442685 scopus 로고    scopus 로고
    • Lymphoid enhancer factor 1 makes cells resistant to transforming growth factor β-induced repression of c-myc
    • Sasaki T, Suzuki H, Yagi K, Furuhashi M, Yao R, Susa S et al. Lymphoid enhancer factor 1 makes cells resistant to transforming growth factor β-induced repression of c-myc. Cancer Res 2003; 63: 801-806.
    • (2003) Cancer Res. , vol.63 , pp. 801-806
    • Sasaki, T.1    Suzuki, H.2    Yagi, K.3    Furuhashi, M.4    Yao, R.5    Susa, S.6
  • 87
    • 0035033521 scopus 로고    scopus 로고
    • β-Catenin-sensitive isoforms of lymphoid enhancer factor-1 are selectively expressed in colon cancer
    • Hovanes K, Li TW, Munguia JE, Truong T, Milovanovic T, Lawrence Marsh J et al. β-Catenin-sensitive isoforms of lymphoid enhancer factor-1 are selectively expressed in colon cancer. Nat Genet 2001; 28: 52-57.
    • (2001) Nat. Genet. , vol.28 , pp. 52-57
    • Hovanes, K.1    Li, T.W.2    Munguia, J.E.3    Truong, T.4    Milovanovic, T.5    Lawrence Marsh, J.6
  • 90
    • 0028982213 scopus 로고
    • Alterations of p27Kip1 gene in non-Hodgkin's lymphomas and adult T cell leukemia/lymphoma
    • Morosetti R, Kawamata N, Gomart AF, Miller CW, Hatta Y, Hirama T et al. Alterations of p27Kip1 gene in non-Hodgkin's lymphomas and adult T cell leukemia/lymphoma. Blood 1995; 86: 1924-1930.
    • (1995) Blood , vol.86 , pp. 1924-1930
    • Morosetti, R.1    Kawamata, N.2    Gomart, A.F.3    Miller, C.W.4    Hatta, Y.5    Hirama, T.6
  • 91
    • 0037071399 scopus 로고    scopus 로고
    • Tumor suppressor genes in normal and malignant hematopoiesis
    • Kruz U, Ganser A, Koeffler HP. Tumor suppressor genes in normal and malignant hematopoiesis. Oncogene 2002; 21: 3475-3495.
    • (2002) Oncogene , vol.21 , pp. 3475-3495
    • Kruz, U.1    Ganser, A.2    Koeffler, H.P.3
  • 92
    • 0017708061 scopus 로고
    • Adult T cell leukemia: Clinical and hematologic features of 16 cases
    • Uchiyama T, Yodoi J, Sagawa K, Takatsuki K, Uchino H. Adult T cell leukemia: clinical and hematologic features of 16 cases. Blood 1977; 50: 481-492.
    • (1977) Blood , vol.50 , pp. 481-492
    • Uchiyama, T.1    Yodoi, J.2    Sagawa, K.3    Takatsuki, K.4    Uchino, H.5
  • 93
    • 0019254359 scopus 로고
    • Detection and isolation of type C retrovirus particles from fresh and cultured lymphocytes of a patient with cutaneous T-cell lymphoma
    • Poiesz BJ, Ruscetti FW, Gazdar AF, Bunn PA, Minna JD, Gallo RC. Detection and isolation of type C retrovirus particles from fresh and cultured lymphocytes of a patient with cutaneous T-cell lymphoma. Proc Natl Acad Sci USA 1980; 77: 7415-7419.
    • (1980) Proc. Natl. Acad. Sci. USA , vol.77 , pp. 7415-7419
    • Poiesz, B.J.1    Ruscetti, F.W.2    Gazdar, A.F.3    Bunn, P.A.4    Minna, J.D.5    Gallo, R.C.6
  • 94
    • 0000904435 scopus 로고
    • Isolation and characterization of retrovirus from cell lines of human adult T-cell leukemia and its implication in the disease
    • Yoshida M, Miyoshi I, Hinuma Y. Isolation and characterization of retrovirus from cell lines of human adult T-cell leukemia and its implication in the disease. Proc Natl Acad Sci USA 1982; 79: 2031-2035.
    • (1982) Proc. Natl. Acad. Sci. USA , vol.79 , pp. 2031-2035
    • Yoshida, M.1    Miyoshi, I.2    Hinuma, Y.3
  • 96
    • 0025858235 scopus 로고
    • HTLV-1 Tax induces expression of various immediate early serum responsive genes
    • Fujii M, Niki T, Mori T, Matsuda T, Matsui M, Nomura N et al. HTLV-1 Tax induces expression of various immediate early serum responsive genes. Oncogene 1991; 6: 1023-1029.
    • (1991) Oncogene , vol.6 , pp. 1023-1029
    • Fujii, M.1    Niki, T.2    Mori, T.3    Matsuda, T.4    Matsui, M.5    Nomura, N.6
  • 98
    • 0026725132 scopus 로고
    • Human T-cell lymphotropic virus type I (HTLV-1) transcriptional activator, Tax, enhances CREB binding to HTLV-I 21-base-pair repeats by protein-protein interaction
    • Zhao LJ, Giam CZ. Human T-cell lymphotropic virus type I (HTLV-1) transcriptional activator, Tax, enhances CREB binding to HTLV-I 21-base-pair repeats by protein-protein interaction. Proc Natl Acad Sci USA 1992; 89: 7070-7074.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 7070-7074
    • Zhao, L.J.1    Giam, C.Z.2
  • 99
    • 0026458078 scopus 로고
    • SRF causes the aberrant induction of cellular immediate early genes through CArG boxes
    • SRF causes the aberrant induction of cellular immediate early genes through CArG boxes. Genes Dev 1992; 6: 2066-2076.
    • (1992) Genes Dev. , vol.6 , pp. 2066-2076
    • Fujii, M.1    Tsuchiya, H.2    Chuhjo, T.3    Akizawa, T.4    Seiki, M.5
  • 100
    • 0031054802 scopus 로고    scopus 로고
    • Human T-cell leukemia virus type 1 Tax releases cell cycle arrest induced by p16INK4a
    • Low KG, Dorner LF, Fernando DB, Grossman J, Jeang KT, Comb MJ. Human T-cell leukemia virus type 1 Tax releases cell cycle arrest induced by p16INK4a. J Virol 1997; 71: 1956-1962.
    • (1997) J. Virol. , vol.71 , pp. 1956-1962
    • Low, K.G.1    Dorner, L.F.2    Fernando, D.B.3    Grossman, J.4    Jeang, K.T.5    Comb, M.J.6
  • 101
    • 0028179915 scopus 로고
    • Human T cell lymphotropic virus type I-induced T cell activation. Resistance to TGF-β1-induced suppression
    • Hollsberg P, Ausubel LJ, Hafler DA. Human T cell lymphotropic virus type I-induced T cell activation. Resistance to TGF-β1-induced suppression. J Immunol 1994; 153: 566-573.
    • (1994) J. Immunol. , vol.153 , pp. 566-573
    • Hollsberg, P.1    Ausubel, L.J.2    Hafler, D.A.3
  • 102
    • 0035312976 scopus 로고    scopus 로고
    • Human T-cell leukemia virus type I oncoprotein Tax represses Smad-dependent transforming growth factor β signaling through interaction with CREB-binding protein/p300
    • Mori N, Morishita M, Tsukazaki T, Giam CZ, Kumatori A, Tanaka Y et al. Human T-cell leukemia virus type I oncoprotein Tax represses Smad-dependent transforming growth factor β signaling through interaction with CREB-binding protein/p300. Blood 2001; 97: 2137-2144.
    • (2001) Blood , vol.97 , pp. 2137-2144
    • Mori, N.1    Morishita, M.2    Tsukazaki, T.3    Giam, C.Z.4    Kumatori, A.5    Tanaka, Y.6
  • 103
    • 0037072767 scopus 로고    scopus 로고
    • Human T-cell lymphotropic virus type 1 tax inhibits transforming growth factor-beta signaling by blocking the association of Smad proteins with Smad-binding element
    • Lee DK, Kim BC, Brady JN, Jeang KT, Kim SJ. Human T-cell lymphotropic virus type 1 tax inhibits transforming growth factor-beta signaling by blocking the association of Smad proteins with Smad-binding element. J Biol Chem 2002; 277: 33766-33775.
    • (2002) J. Biol. Chem. , vol.277 , pp. 33766-33775
    • Lee, D.K.1    Kim, B.C.2    Brady, J.N.3    Jeang, K.T.4    Kim, S.J.5
  • 104
    • 0036891934 scopus 로고    scopus 로고
    • Human T-cell lymphotropic virus oncoprotein Tax represses TGF-β1 signaling in human T cells via c-jun activation: A potential mechanism of HTLV-I leukemogenesis
    • Arnulf B, Villemain A, Nicot C, Mordelet E, Charneau P, Kersual J et al. Human T-cell lymphotropic virus oncoprotein Tax represses TGF-β1 signaling in human T cells via c-jun activation: a potential mechanism of HTLV-I leukemogenesis. Blood 2002; 100: 4129-4138.
    • (2002) Blood , vol.100 , pp. 4129-4138
    • Arnulf, B.1    Villemain, A.2    Nicot, C.3    Mordelet, E.4    Charneau, P.5    Kersual, J.6
  • 105
    • 0025287105 scopus 로고
    • Transactivation of the transforming growth factor β1 (TGF-β1) gene by human T lymphotropic virus type 1 tax: A potential mechanism for the increased production of TGF-β1 in adult T cell leukemia
    • Kim SJ, Kehrl JH, Burton J, Tendler CL, Jeang KT, Danielpour D et al. Transactivation of the transforming growth factor β1 (TGF-β1) gene by human T lymphotropic virus type 1 tax: a potential mechanism for the increased production of TGF-β1 in adult T cell leukemia. J Exp Med 1990; 172: 121-129.
    • (1990) J. Exp. Med. , vol.172 , pp. 121-129
    • Kim, S.J.1    Kehrl, J.H.2    Burton, J.3    Tendler, C.L.4    Jeang, K.T.5    Danielpour, D.6
  • 106
    • 0025999811 scopus 로고
    • Overexpression of transforming growth factor-β in transgenic mice carrying the human T-cell lymphotropic virus type I tax gene
    • Kim SJ, Winokur TS, Lee HD, Danielpour D, Kim KY, Geiser AG et al. Overexpression of transforming growth factor-β in transgenic mice carrying the human T-cell lymphotropic virus type I tax gene. Mol Cell Biol 1991; 11: 5222-5228.
    • (1991) Mol. Cell Biol. , vol.11 , pp. 5222-5228
    • Kim, S.J.1    Winokur, T.S.2    Lee, H.D.3    Danielpour, D.4    Kim, K.Y.5    Geiser, A.G.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.