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Volumn 95, Issue 10, 2000, Pages 3001-3010

Modulation of bcl-2 and p27 in human primitive proliferating hematopoietic progenitors by autocrine TGF-β1 is a cell cycle-independent effect and influences their hematopoietic potential

Author keywords

[No Author keywords available]

Indexed keywords

CD34 ANTIGEN; CELL CYCLE PROTEIN; ENDOGLIN; MYC PROTEIN; NEUTRALIZING ANTIBODY; PROTEIN BCL 2; PROTEIN P27; PROTEIN P53; TRANSCRIPTION FACTOR GATA 1; TRANSFORMING GROWTH FACTOR BETA1;

EID: 0034657830     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v95.10.3001.009k34a_3001_3009     Document Type: Article
Times cited : (57)

References (43)
  • 2
    • 0027999617 scopus 로고
    • Structure and function of p53 in normal cells and their aberrations in cancer cells: Projection on the hematologic cell lineages
    • Prokocimer M, Rotter V. Structure and function of p53 in normal cells and their aberrations in cancer cells: projection on the hematologic cell lineages. Blood. 1994;84:2391.
    • (1994) Blood , vol.84 , pp. 2391
    • Prokocimer, M.1    Rotter, V.2
  • 3
    • 0028040019 scopus 로고
    • Bcl-2 and the regulation of programmed cell death
    • Reed JC. Bcl-2 and the regulation of programmed cell death. J Cell Biol. 1994;124:1.
    • (1994) J Cell Biol. , vol.124 , pp. 1
    • Reed, J.C.1
  • 4
    • 0027494821 scopus 로고
    • Signal transduction by the high-affinity GM-CSF receptor: Two distinct cytoplasmic regions of the common beta subunit responsible for different signaling
    • Sato N, Sakamaki K, Terada N, Arai K, Miyajima A. Signal transduction by the high-affinity GM-CSF receptor: two distinct cytoplasmic regions of the common beta subunit responsible for different signaling. EMBO J. 1993;12:4181.
    • (1993) EMBO J. , vol.12 , pp. 4181
    • Sato, N.1    Sakamaki, K.2    Terada, N.3    Arai, K.4    Miyajima, A.5
  • 5
    • 0028837491 scopus 로고
    • Suppression of apoptotic death in hematopoietic cells by signalling through the IL-3/GM-CSF receptors
    • Kinoshita T, Yokota T, Arai K, Miyajima A. Suppression of apoptotic death in hematopoietic cells by signalling through the IL-3/GM-CSF receptors. EMBO J. 1995;14:266.
    • (1995) EMBO J. , vol.14 , pp. 266
    • Kinoshita, T.1    Yokota, T.2    Arai, K.3    Miyajima, A.4
  • 6
    • 0027537118 scopus 로고
    • Suppression of apoptosis in a cytotoxic T-cell line by interleukin 2-mediated gene transcription and deregulated expression of the protooncogene bcl-2
    • Deng G, Podack ER. Suppression of apoptosis in a cytotoxic T-cell line by interleukin 2-mediated gene transcription and deregulated expression of the protooncogene bcl-2. Proc Natl Acad Sci U S A. 1993;90:2189.
    • (1993) Proc Natl Acad Sci U S A , vol.90 , pp. 2189
    • Deng, G.1    Podack, E.R.2
  • 7
  • 8
    • 0343081652 scopus 로고    scopus 로고
    • High cdk inhibitors and p53 levels in Bcl-2 and Bcl-xL-expressing primitive proliferating hematopoietic progenitors
    • Marone M, Pierelli L, Mozzetti S, et al. High cdk inhibitors and p53 levels in Bcl-2 and Bcl-xL-expressing primitive proliferating hematopoietic progenitors. Exp Hematol. 1999;27(suppl 1):108.
    • (1999) Exp Hematol. , vol.27 , Issue.SUPPL. 1 , pp. 108
    • Marone, M.1    Pierelli, L.2    Mozzetti, S.3
  • 9
    • 0028364494 scopus 로고
    • c-myc and bcl-2 modulate p53 function by altering p53 subcellular trafficking during the cell cycle
    • Ryan JJ, Prochownik E, Gottlieb CA, et al. c-myc and bcl-2 modulate p53 function by altering p53 subcellular trafficking during the cell cycle. Proc Natl Acad Sci U S A. 1994;91:5878.
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 5878
    • Ryan, J.J.1    Prochownik, E.2    Gottlieb, C.A.3
  • 10
    • 0025222517 scopus 로고
    • The transforming growth factor-β1 family
    • Massague J. The transforming growth factor-β1 family. Annu Rev Cell Biol. 1990;6:597.
    • (1990) Annu Rev Cell Biol. , vol.6 , pp. 597
    • Massague, J.1
  • 11
    • 7344233740 scopus 로고    scopus 로고
    • Functional, phenotypic and molecular characterization of cytokine low-responding circulating CD34+ haemopoietic progenitors
    • Pierelli L, Scambia G, Fattorossi A, et al. Functional, phenotypic and molecular characterization of cytokine low-responding circulating CD34+ haemopoietic progenitors. Br J Haematol. 1998; 102:1139.
    • (1998) Br J Haematol. , vol.102 , pp. 1139
    • Pierelli, L.1    Scambia, G.2    Fattorossi, A.3
  • 12
    • 0029075332 scopus 로고
    • Quercetin inhibits the growth of leukemic progenitors and induces the expression of transforming growth factor-beta 1 in these cells
    • Larocca LM, Teofili L, Sica S, et al. Quercetin inhibits the growth of leukemic progenitors and induces the expression of transforming growth factor-beta 1 in these cells. Blood. 1995;85:3654.
    • (1995) Blood , vol.85 , pp. 3654
    • Larocca, L.M.1    Teofili, L.2    Sica, S.3
  • 13
    • 0032979030 scopus 로고    scopus 로고
    • Expansion of granulocyte colony-stimulating factor/ chemotherapy-mobilized CD34+ hematopoietic progenitors: Role of granulocyte-macrophage colony-stimulating factor/erythropoietin hybrid protein (MEN11303) and interleukin-15
    • Pierelli L, Scambia G, Bonanno G, et al. Expansion of granulocyte colony-stimulating factor/ chemotherapy-mobilized CD34+ hematopoietic progenitors: role of granulocyte-macrophage colony-stimulating factor/erythropoietin hybrid protein (MEN11303) and interleukin-15. Exp Hematol. 1999;27:416.
    • (1999) Exp Hematol. , vol.27 , pp. 416
    • Pierelli, L.1    Scambia, G.2    Bonanno, G.3
  • 14
    • 0031939573 scopus 로고    scopus 로고
    • Bcl-2, bax, bcl-xL and bcl-xS expression in normal and neoplastic ovarian tissues
    • Marone M, Scambia G, Mozzetti S, et al. Bcl-2, bax, bcl-xL and bcl-xS expression in normal and neoplastic ovarian tissues. Clin Cancer Res. 1998;4:517.
    • (1998) Clin Cancer Res. , vol.4 , pp. 517
    • Marone, M.1    Scambia, G.2    Mozzetti, S.3
  • 15
    • 0028151418 scopus 로고
    • Monitoring mRNA expression by polymerase chain reaction by the 'primer dropping' method
    • Whong H, Anderson WD, Cheng T, Riabowol KT. Monitoring mRNA expression by polymerase chain reaction by the 'primer dropping' method. Anal Biochem. 1994;223:251.
    • (1994) Anal Biochem. , vol.223 , pp. 251
    • Whong, H.1    Anderson, W.D.2    Cheng, T.3    Riabowol, K.T.4
  • 16
    • 0027426737 scopus 로고
    • Alternative splicing of the p53 tumor suppressor gene in the Molt-4 T-lymphoblastic leukemia cell line
    • Chow WT, Queck HH, Tock EP. Alternative splicing of the p53 tumor suppressor gene in the Molt-4 T-lymphoblastic leukemia cell line. Cancer Lett. 1993;73:141.
    • (1993) Cancer Lett. , vol.73 , pp. 141
    • Chow, W.T.1    Queck, H.H.2    Tock, E.P.3
  • 17
    • 0030865680 scopus 로고    scopus 로고
    • A novel, myeloid transcription factor, C/EBPε is upregulated during granulocytic, but not monocytic, differentiation
    • Morosetti R, Park DJ, Chumakov AM, et al. A novel, myeloid transcription factor, C/EBPε is upregulated during granulocytic, but not monocytic, differentiation. Blood. 1997;90:2591.
    • (1997) Blood , vol.90 , pp. 2591
    • Morosetti, R.1    Park, D.J.2    Chumakov, A.M.3
  • 18
    • 0029156492 scopus 로고
    • Primitive human hematopoietic precursors express bcl-x but not bcl-2
    • Park JR, Bernstein ID, Hockenbery DM. Primitive human hematopoietic precursors express bcl-x but not bcl-2. Blood. 1995;86:868.
    • (1995) Blood , vol.86 , pp. 868
    • Park, J.R.1    Bernstein, I.D.2    Hockenbery, D.M.3
  • 19
    • 0025940505 scopus 로고
    • Release of early human hematopoietic progenitors from quiescence by antisense transforming growth factor β1 or Rb oligonucleotides
    • Hatzfeld J, Li M-L, Brown EL, et al. Release of early human hematopoietic progenitors from quiescence by antisense transforming growth factor β1 or Rb oligonucleotides. J Exp Med. 1991;174: 925.
    • (1991) J Exp Med. , vol.174 , pp. 925
    • Hatzfeld, J.1    Li, M.-L.2    Brown, E.L.3
  • 20
    • 0025880646 scopus 로고    scopus 로고
    • Mechanisms that regulate the cell cycle status of very primitive hematopoietic cells in long-term human marrow cultures. II. Analysis of positive and negative regulators produced by stromal cells within the adherent layer
    • Eaves CJ, Cashman JD, Kay RJ, et al. Mechanisms that regulate the cell cycle status of very primitive hematopoietic cells in long-term human marrow cultures. II. Analysis of positive and negative regulators produced by stromal cells within the adherent layer. Blood. 1997;78:110.
    • (1997) Blood , vol.78 , pp. 110
    • Eaves, C.J.1    Cashman, J.D.2    Kay, R.J.3
  • 21
    • 13344284647 scopus 로고    scopus 로고
    • Accelerated cell-cycling of hematopoietic progenitors by the flt3 ligand that is modulated by transforming growth factor-beta
    • Ohishi K, Katayama N, Itoh R, et al. Accelerated cell-cycling of hematopoietic progenitors by the flt3 ligand that is modulated by transforming growth factor-beta. Blood. 1996;87:1718.
    • (1996) Blood , vol.87 , pp. 1718
    • Ohishi, K.1    Katayama, N.2    Itoh, R.3
  • 22
    • 0029153609 scopus 로고
    • Kip/Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-β
    • Renysdottir I, Polyak K, Iavarone A, Massague J. Kip/Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-β. Genes Dev. 1995;9:1831.
    • (1995) Genes Dev. , vol.9 , pp. 1831
    • Renysdottir, I.1    Polyak, K.2    Iavarone, A.3    Massague, J.4
  • 23
    • 0025326725 scopus 로고
    • Growth inhibition by TGF-β1 linked to suppression of retinoblastoma protein phosphorylation
    • Laiho M, DeCaprio JA, Ludlow JW, Livingston DM, Massague J. Growth inhibition by TGF-β1 linked to suppression of retinoblastoma protein phosphorylation. Cell. 1990;62:175.
    • (1990) Cell , vol.62 , pp. 175
    • Laiho, M.1    DeCaprio, J.A.2    Ludlow, J.W.3    Livingston, D.M.4    Massague, J.5
  • 24
    • 0029880007 scopus 로고    scopus 로고
    • Transforming growth factor-beta1 modulates p107 function in myeloid cells: Correlation with cell cycle progression
    • Bang OS, Ruscetti FW, Lee MH, Kim SJ, Birchenall-Roberts MC. Transforming growth factor-beta1 modulates p107 function in myeloid cells: correlation with cell cycle progression. J Biol Chem. 1996;271:7811.
    • (1996) J Biol Chem. , vol.271 , pp. 7811
    • Bang, O.S.1    Ruscetti, F.W.2    Lee, M.H.3    Kim, S.J.4    Birchenall-Roberts, M.C.5
  • 25
    • 0032573177 scopus 로고    scopus 로고
    • Reduction in levels of the cyclin-dependent kinase inhibitor p27kip-1 coupled with transforming growth factor β neutralization induces cell-cycle entry and increases retroviral transduction of primitive human hematopoietic cells
    • Dao MA, Taylor N, Nolta JA. Reduction in levels of the cyclin-dependent kinase inhibitor p27kip-1 coupled with transforming growth factor β neutralization induces cell-cycle entry and increases retroviral transduction of primitive human hematopoietic cells. Proc Natl Acad Sci U S A. 1998;95: 13,006.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 13006
    • Dao, M.A.1    Taylor, N.2    Nolta, J.A.3
  • 26
    • 0031851630 scopus 로고    scopus 로고
    • High proliferative potential-quiescent cells: A working model to study primitive quiescent hematopoietic cells
    • Fortunel N, Batard P, Hatzfeld A, et al. High proliferative potential-quiescent cells: a working model to study primitive quiescent hematopoietic cells. J Cell Sci. 1998;111:1867.
    • (1998) J Cell Sci. , vol.111 , pp. 1867
    • Fortunel, N.1    Batard, P.2    Hatzfeld, A.3
  • 27
    • 0030946194 scopus 로고    scopus 로고
    • TGF-β latency: Biological significance and mechanism of activation
    • Gleizes P-E, Munger JS, Nunes I, et al. TGF-β latency: biological significance and mechanism of activation. Stem Cells. 1997;15:190.
    • (1997) Stem Cells , vol.15 , pp. 190
    • Gleizes, P.-E.1    Munger, J.S.2    Nunes, I.3
  • 28
    • 0028575840 scopus 로고
    • Regulation of neuronal bcl-2 protein expression and calcium homeostasis by transforming growth factor type β confers wide-ranging protection on rat hippocampal neurons
    • Prehn JHM, Bindokas VP, Marcuccilli CJ, Krajewski S, Reed JC, Miller RJ. Regulation of neuronal bcl-2 protein expression and calcium homeostasis by transforming growth factor type β confers wide-ranging protection on rat hippocampal neurons. Proc Natl Acad Sci U S A. 1994;91:12,599.
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 12599
    • Prehn, J.H.M.1    Bindokas, V.P.2    Marcuccilli, C.J.3    Krajewski, S.4    Reed, J.C.5    Miller, R.J.6
  • 29
    • 0030579193 scopus 로고    scopus 로고
    • Transforming growth factor-β is a survival factor for neonate cortical neurons: Coincident expression of type I receptors in developing cerebral cortices
    • Tomoda T, Shirasawa T, Yahagi Y-I, et al. Transforming growth factor-β is a survival factor for neonate cortical neurons: coincident expression of type I receptors in developing cerebral cortices. Dev Biol. 1996;179:79.
    • (1996) Dev Biol. , vol.179 , pp. 79
    • Tomoda, T.1    Shirasawa, T.2    Yahagi, Y.-I.3
  • 30
    • 0032951763 scopus 로고    scopus 로고
    • Possible involvement of bcl-2 in regulation of cell-cycle progression of haemopoietic cells by transforming growth factor-β1
    • Mahmud N, Katayama N, Nishii K, et al. Possible involvement of bcl-2 in regulation of cell-cycle progression of haemopoietic cells by transforming growth factor-β1. Br J Haematol. 1999;105: 470.
    • (1999) Br J Haematol. , vol.105 , pp. 470
    • Mahmud, N.1    Katayama, N.2    Nishii, K.3
  • 31
    • 0028284281 scopus 로고
    • Effects of bcl-2 antisense oligodeoxynucleotides on in vitro proliferation and survival of normal marrow progenitors and leukemic cells
    • Campos L, Sabido O, Rouault J-R, Guyotat D. Effects of bcl-2 antisense oligodeoxynucleotides on in vitro proliferation and survival of normal marrow progenitors and leukemic cells. Blood. 1994;84:595.
    • (1994) Blood , vol.84 , pp. 595
    • Campos, L.1    Sabido, O.2    Rouault, J.-R.3    Guyotat, D.4
  • 32
    • 0029835789 scopus 로고    scopus 로고
    • Interleukin-10 increases bcl-2 expression and survival in primary human CD34+ hematopoietic progenitor cells
    • Weber-Nordt RM, Henschler R, Schott E, et al. Interleukin-10 increases bcl-2 expression and survival in primary human CD34+ hematopoietic progenitor cells. Blood, 1996;88:2549.
    • (1996) Blood , vol.88 , pp. 2549
    • Weber-Nordt, R.M.1    Henschler, R.2    Schott, E.3
  • 33
    • 0028179669 scopus 로고
    • p27kip1, a cyclin-Cdk inhibitor, links transforming growth factor-β and contact inhibition to cell cycle arrest
    • Polyak K, Kato J-Y, Solomon MJ, et al. p27kip1, a cyclin-Cdk inhibitor, links transforming growth factor-β and contact inhibition to cell cycle arrest. Genes Dev. 1994;8:9.
    • (1994) Genes Dev. , vol.8 , pp. 9
    • Polyak, K.1    Kato, J.-Y.2    Solomon, M.J.3
  • 34
    • 0028941963 scopus 로고
    • TGFβ-induced activation of cyclin E-cdk2 kinase and downregulation of p27kip1 in C3H10T1/2 mouse fibroblasts
    • Ravitz MJ, Yan S, Herr KD, Wenner C. TGFβ-induced activation of cyclin E-cdk2 kinase and downregulation of p27kip1 in C3H10T1/2 mouse fibroblasts. Cancer Res. 1995; 55:1413.
    • (1995) Cancer Res. , vol.55 , pp. 1413
    • Ravitz, M.J.1    Yan, S.2    Herr, K.D.3    Wenner, C.4
  • 35
    • 0033135934 scopus 로고    scopus 로고
    • Subcellular and cell-cycle expression profiles of CDK-inhibitors in normal differentiating myeloid cells
    • Yaroslavskiy B, Watkins S, Donnenberg AD, Patton TJ, Steinman RA. Subcellular and cell-cycle expression profiles of CDK-inhibitors in normal differentiating myeloid cells. Blood. 1999;93:2907.
    • (1999) Blood , vol.93 , pp. 2907
    • Yaroslavskiy, B.1    Watkins, S.2    Donnenberg, A.D.3    Patton, T.J.4    Steinman, R.A.5
  • 36
    • 0001208875 scopus 로고    scopus 로고
    • Cyclin-dependent kinase inhibitor p27 as a mediator of the G1-S phase block induced by 1,25-dihydroxyvitamin D3 in HL60 cells
    • Wang QM, Jones JB, Studzinski GP. Cyclin-dependent kinase inhibitor p27 as a mediator of the G1-S phase block induced by 1,25-dihydroxyvitamin D3 in HL60 cells. Cancer Res. 1996;56:264.
    • (1996) Cancer Res. , vol.56 , pp. 264
    • Wang, Q.M.1    Jones, J.B.2    Studzinski, G.P.3
  • 38
    • 0029876726 scopus 로고    scopus 로고
    • The transcriptional control of hematopoiesis
    • Shivdasani R, Orkin SH. The transcriptional control of hematopoiesis. Blood. 1996;87:4025.
    • (1996) Blood , vol.87 , pp. 4025
    • Shivdasani, R.1    Orkin, S.H.2
  • 39
    • 0030700268 scopus 로고    scopus 로고
    • Transforming growth factor beta 1 attenuates ceramide-induced CPP32/Yama activation and apoptosis in human leukaemic HL-60 cells
    • Kuo ML, Chen CW, Jee SH, Chuang SE, Cheng AL. Transforming growth factor beta 1 attenuates ceramide-induced CPP32/Yama activation and apoptosis in human leukaemic HL-60 cells. Biochem J. 1997;327:663.
    • (1997) Biochem J. , vol.327 , pp. 663
    • Kuo, M.L.1    Chen, C.W.2    Jee, S.H.3    Chuang, S.E.4    Cheng, A.L.5
  • 40
    • 0030877457 scopus 로고    scopus 로고
    • Cell density-dependent apoptosis in HL-60 cells, which is mediated by an unknown soluble factor, is inhibited by transforming growth factor beta1 and overexpression of bcl-2
    • Saeki K, Yuo A, Kato M, Miyazono K, Yazaki Y, Takaku F. Cell density-dependent apoptosis in HL-60 cells, which is mediated by an unknown soluble factor, is inhibited by transforming growth factor beta1 and overexpression of bcl-2. J Biol Chem. 1997;272:20,003.
    • (1997) J Biol Chem. , vol.272 , pp. 20003
    • Saeki, K.1    Yuo, A.2    Kato, M.3    Miyazono, K.4    Yazaki, Y.5    Takaku, F.6
  • 42
    • 0030911358 scopus 로고    scopus 로고
    • Purification of primitive human hematopoietic cells capable of repopulating immunodeficient mice
    • Bhatia M, Wang JCY, Kapp U, Bonnet D, Dick JE. Purification of primitive human hematopoietic cells capable of repopulating immunodeficient mice. Proc Natl Acad Sci U S A. 1997;94:5320.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 5320
    • Bhatia, M.1    Wang, J.C.Y.2    Kapp, U.3    Bonnet, D.4    Dick, J.E.5
  • 43
    • 0030788152 scopus 로고    scopus 로고
    • Quantitative analysis reveals expansion of human hematopoietic repopulating cells after short-term ex vivo culture
    • Bhatia M, Bonnet D, Kapp U, Wang JCY, Murdoch B, Dick JE. Quantitative analysis reveals expansion of human hematopoietic repopulating cells after short-term ex vivo culture. J Exp Med. 1997;186:619.
    • (1997) J Exp Med. , vol.186 , pp. 619
    • Bhatia, M.1    Bonnet, D.2    Kapp, U.3    Wang, J.C.Y.4    Murdoch, B.5    Dick, J.E.6


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