TGF-β-activating kinase-1 inhibits cell cycle and expression of cyclin D1 and A in LLC-PK1 cells

Kidney International

Volumn 56, Issue 4, 1999, Pages 1378-1390

  Terada, Yoshio ^a   Nakashima, Osamu ^a   Inoshita, Seiji ^a   Kuwahara, Michio ^a   Sasaki, Sei ^a   Marumo, Fumiaki ^a  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

Author keywords

Cell cycle; MAP kinase; p38 kinase; Renal tubule

Indexed keywords

CYCLIN A; CYCLIN D1; MITOGEN ACTIVATED PROTEIN KINASE; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL CELL; CONFERENCE PAPER; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME REGULATION; KIDNEY TUBULE CELL; KIDNEY TUBULE DISORDER; MITOSIS INHIBITION; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION;

EID: 0032872650     PISSN: 00852538     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1755.1999.00665.x     Document Type: Conference Paper

References (42)

1. BORDER WA, NOBLE NA. Transforming growth factor β in tissue fibrosis. N EnglJ Med 331:1286-1292, 1994
2. BORDER WA, RUOSLAHTI E. Transforming growth factor β in disease. The dark side of tissue repair. J Clin Invest 90:1-7, 1992
3. BACALLAO R, FINE LG. Molecular events in the organization of renal tubular epithelium. From nephrogenesis to regeneration. Am J Physiol 257:F913-F924, 1989
4. EKBLOM P. Developmentally regulated conversion of mesenchyme to epithelium. FASEB J 3:2141-2150, 1989
5. CLOUTHIER DE, COMERFORD SA, HAMMER RE. Hepatic fibrosis, glomerulosclerosis, and a lipodystrophy-like syndrome in PEPCKTGF-β1 transgenic mice. J Clin, Invest 100:2697-2713, 1997
6. AVRUCH J, ZHANG XF, KYRIAKIS JM. Raf meets Ras. Completing the framework of a signal transduction pathway. Trends Biochem Sei 19:279-283, 1994
7. COBB MH, GOLDSMITH EJ. How MAP kinases are regulated. J Biol Chem 270:14843-14846, 1995
8. SEGER R, SEGER D, RESZKA AA, MUNAR ES, ELDAR FM, DOBROWOLSKA G, JENSEN AM, CAMPBELL JS, FISCHER EH, KREBS EG. Overexpression of mitogen-activated protein kinase kinase (MAPKK) and its mutants in NIH 3T3 cells. Evidence that MAPKK involvement in cellular proliferation is regulated by phosphorylation of serine residues in its kinase subdomains VII and VIII. J Biol Chem 269:25699-25709, 1994
9. PAGES G, LENORMAND PL, L'ALLEMAIN G, CHAMBARD JC, MELOCHE S, POUYSSEGUR J. Mitogen-activated protein kinases p42mapk and p44mapk are required for fibroblast proliferation. Proc Natl Acad Sei USA 90:8319-8323, 1993
10. SHIBUYA H, YAMAGUCHI K, SHIRAKABE K, TONEOAWA A, GOTOH Y, UENO N, IRIE K, NISHIDA E, MATSUMOTO K. TAB1. An activator of the TAK1 MAPKKK in TGF-β signal transduction. Science 272:1179-1182, 1996
11. SHIRAKABE K, YAMAGUCHI K, SHIBUYA H, IRIE K, MATSUDA S, MORIGUCHI T, GOTOH Y, MATSUMOTO K, NISHIDA E. TAK1 mediates the ceramide signaling to stress-activated protein kinase/c-Jun N-terminal kinase. J Biol Chem 272:8141-8144, 1997
12. YAMAGUCHI K, SHIRAKABE K, SHIBUYA H, IRIE K, OISHI I, UENO N, TANIGUCHI T, NISHIDA E, MATSUMOTO K. Identification of a member of the MAPKKK family as a potential mediator of TGF-β signal transduction. Science 270:2008-2011, 1995
13. MORIGUCHI T, KUROYANAGI N, YAMAGUCHI K, GOTOH Y, IRIE K, KANO T, SHIRAKABE K, MURO Y, SHIBUYA H, MATSUMOTO K, NISHIDA E, HAGIWARA M. A novel kinase cascade mediated by mitogen-activated protein kinase kinase 6 and MKK3. J Biol Chem 271:13675-13679, 1996
14. MASSAGUE J. The transforming growth factor-β family. Annu Rev Cell Biol 6:597-641, 1990
15. MOSES HL, YANG EY, PIETENPOL JA. TGF-β stimulation and inhibition of cell proliferation. New mechanistic insights. Cell 63:245-247, 1990
16. EWEN ME, SLUSS HK, WHITEHOUSE LL, LIVINGSTON DM. TGF β inhibition of Cdk4 synthesis is linked to cell cycle arrest. Cell 74:1009-1020, 1993
17. KOFF A, OHTSUKI M, POLYAK K, ROBERTS JM, MASSAGUE J. Negative regulation of Gl in mammalian cells. Inhibition of cyclin Edependent kinase by TGF-β. Science 260:536-539, 1993
18. Li CY, SUARDET L, LITTLE JB. Potential role of WAF1/Cip1/p21 as a mediator of TGF-β cytoinhibitory effect. J Biol Chem 270:4971-4974, 1995
19. HANNON GJ, BEACH D. p15INK4B is a potential effector of TGF-β-induced cell cycle arrest. Nature 371:257-261, 1994
20. TOYOSHIMA H, HUNTER T. p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21. Cell 78:67-74, 1994
21. LAVOIE JNL, L'ALLEMAIN G, BRUNET A, MULLER R, POUYSSEGUR J. Cyclin D1 expression is regulated positively by the p42/ p44MAPK and negatively by the p38/HOGMAPK pathway. J Biol Cliem 271:20608-20616, 1996
22. CUENDA A, ROUSE J, DOZA YN, MEIER R, COHEN P, GALLAGHER TF, YOUNG PR, LEE JC. SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1. FEBS Lett 364:229-233, 1995
23. RAINGEAUD J, WHITMARSH AJ, BARRETT T, DERIJARD B, DAVIS RJ. MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway. Mol Cell Biol 16:1247-1255, 1996
24. SOLOMON DL, PHILIPP A, LAND H, EILERS M. Expression of cyclin Dl mRNA is not upregulated by Myc in rat fibroblasts. Oncogens 11:1893-1897, 1995
25. DESDOUETS C, ORY C, MATESIC G, Soussi T, BRECHOT C, SOBCZAK TJ. ATF/CREB site mediated transcriptional activation and p53 dependent repression of the cyclin A promoter. FEBS Lett 385:34-38, 1996
26. OHTANI K, DEGREGORI J, NEVINS JR. Regulation of the cyclin E gene by transcription factor E2F1. Proc Natl Acad Sci USA 92:12146-12150, 1995
27. TERADA Y, INOSHITA S, NAKASHIMA O, YAMADA T, TAMAMORI M, ITO H, SASAKI S, MARUMO F. Cyclin Dl, p16, and retinoblastoma gene regulate mitogenic signaling of endothelin in rat mesangial cells. Kidney lut 53:76-83, 1998
28. FRANCH HA, SHAY JW, ALPERN RJ, PREISIG PA. Involvement of pRB family in TGF beta-dependent epithelial cell hypertrophy. J Cell Biol 129:245-254, 1995
29. WOLF G, MUELLER E, STAHL RA, ZIYADEH FN. Angiotensin II-induced hypertrophy of cultured murine proximal tubular cells is mediated by endogenous transforming growth factor-beta. J Clin Invest 92:1366-1372, 1993
30. SHERR CJ. Cancer cell cycles. Science 274:1672-1677, 1996
31. HUNTER T, PINES J. Cyclins and cancer. II. Cyclin D and CDK inhibitors come of age. Cell 79:573-582, 1994
32. PARK SK, KANG MJ, KIM W, Kon GY. Renal tubule regeneration after ischemic injury is coupled to the up-regulation and activation of cyclins and cyclin dependent kinases. Kidney lut 52:706-714, 1997
33. SHANKLAND SJ, KAMEL P, SCHOLEY JW. Cyclin and cyclin-dependent kinase expression in the remnant glomerulus. J Am Soc Nephrol 8:368-375, 1997
34. MEGYESI J, UDVARHELYI N, SAFIRSTEIN RL, PRICE PM. The p53-independent activation of transcription of p21 WAF1/CIP1/SDI1 after acute renal failure. Am J Physiol 271:F1211-F1216, 1996
35. GIRARD F, STRAUSFELD U, FERNANDEZ A, LAMB NJ. Cyclin A is required for the onset of DNA replication in mammalian fibroblasts. Cell 67:1169-1179, 1991
36. SATTERWHITE DJ, AAKRE ME, GORSKA AE, MOSES HL. Inhibition of cell growth by TGFβ1 is associated with inhibition of B-myb and cyclin A in both BALB/MK and MvlLu cells. Cell Growth Differ 5:789-799, 1994
37. SYLVESTER AM, CHEN D, KRASINSKI K, ANDRES V. Role of c-fos and E2F in the induction of cyclin A transcription and vascular smooth muscle cell proliferation. J Clin Invest 101:940-948, 1998
38. MATSUSHIME H, ROUSSEL MF, ASHMUN RA, SHERR CJ. Colonystimulating factor 1 regulates novel cyclins during the G1 phase of the cell cycle. Cell 65:701-713, 1991
39. Ko TC, SHENG HM, REISMAN D, THOMPSON EA, BEAUCHAMP RD. Transforming growth factor-beta 1 inhibits cyclin Dl expression in intestinal epithelial cells. Oncogene 10:177-184, 1995
40. TERADA Y, YAMADA T, TAKAYAMA M, NONOGUCHI H, SASAKI S, TOMITA K, MARUMO F. Presence and regulation of Raf-1-K (kinase), MAPK-K, MAP-K, and S6-K in rat nephron segments. J Am Soc Nephrol 6:1565-1577, 1995
41. TAIRA T, YOSHIMURA A, IIZUKA K, INUI K, OSHIDEN K, IWASAKI S, IDEURA T, KOSHIKAWA S. Expression of epidermal growth factor and its receptor in rabbits with ischaemic acute renal failure. Virchows Arch 427:583-588, 1996
42. DING HJ, KOPPLE JD, COHEN A, HIRSCHBERG R. Recombinant human insulin-like growth factor-I accelerates recovery and reduces catabolism in rats with ischemic acute renal failure. J Clin Invest 91:2281-2287, 1993