p21(cip1) mRNA is controlled by endogenous transforming growth factor- β1 in quiescent human hematopoietic stem/progenitor cells

Journal of Cellular Physiology

Volumn 184, Issue 1, 2000, Pages 80-85

  Ducos, Karin ^a   Panterne, Beatrice ^a   Fortunel, Nicolas ^a   Hatzfeld, Antoinette ^a   Monier, Marie Noelle ^a   Hatzfeld, Jacques ^a  

^a CNRS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; PROTEIN P21; TRANSFORMING GROWTH FACTOR BETA1;

ARTICLE; CELL CYCLE; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN ANALYSIS; REGULATORY MECHANISM; STEM CELL;

ANTIGENS, CD34; CELL CYCLE; CELL DIVISION; CELLS, CULTURED; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLINS; ENZYME INHIBITORS; FETAL BLOOD; GENE EXPRESSION REGULATION; HEMATOPOIETIC STEM CELLS; HUMANS; INFANT, NEWBORN; KINETICS; OLIGODEOXYRIBONUCLEOTIDES, ANTISENSE; RECOMBINANT PROTEINS; TRANSCRIPTION, GENETIC; TRANSFORMING GROWTH FACTOR BETA;

EID: 0034040637     PISSN: 00219541     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4652(200007)184:1<80::AID-JCP8>3.0.CO;2-Q     Document Type: Article

References (43)

1. Angerer LM, Cox KH, Angerer RC. 1987. Demonstration of tissue-specific gene expression by in situ hybridization. Methods Enzymol 152:649-661.
2. Bernaudin JF, Yamauchi K, Wewers MD, Tocci MJ, Ferrans VJ, Crystal RG. 1988. Demonstration by in situ hybridization of dissimilar IL-1 β gene expression in human alveolar macrophages and blood monocytes in response to lipopolysaccharide. J Immunol 140: 3822-3829.
3. Biggs JR, Kudlow JE, Kraft AS. 1996. The role of the transcription factor Sp1 in regulating the expression of the WAF1/CIP1 gene in U937 leukemic cells. J Biol Chem 271:901-906.
4. Brossard Y, Van Nifterik J, De Lachaux V, Huchet J, Chavinie J, Francoual C, Lemanceau G, Benbunan M, Gerota I, Traineau R, Adam M, Gluckman E, Richard P, Thierry D. 1990. Collection of placental blood with a view to hemopoietic reconstitution. Nouv Rev Fr Hématol 32:427-429.
5. - human umbilical cord blood cells reveals their potentiality to engraft adults. Proc Natl Acad Sci USA 90:8707-8711.
6. Cashman JD, Eaves AC, Raines EW, Ross R, Eaves CJ. 1990. Mechanisms that regulate the cell cycle status of very primitive hematopoietic cells in long-term human marrow cultures. I. Stimulatory role of a variety of mesenchymal cell activators and inhibitory role of TGF-β. Blood 75:96-101.
7. Dao MA, Taylor N, Nolta JA. 1998. Reduction in levels of the cyclin-dependent kinase inhibitor p27(Kip-1) coupled with transforming growth factor β neutralization induced cell-cycle entry and increases retroviral transduction of primitive human hematopoietic cells. Proc Natl Acad Sci USA 95:13006-13011.
8. Datto MB, Li Y, Panus JF, Howe DJ, Xiong Y, Wang XF. 1995. Transforming growth factor β induces the cyclin-dependent kinase inhibitor p21 through a p53-independent mechanism. Proc Natl Acad Sci USA 92:5545-5549.
9. Dubois CM, Ruscetti FW, Stankova J, Keller JR. 1994. Transforming growth factor-β regulates c-kit message stability and cell-surface protein expression in hematopoietic progenitors. Blood 83:3138-3145.
10. Eaves CJ, Cashman JD, Kay RJ, Dougherty GJ, Otsuka T, Gaboury LA, Hogge DE, Lansdorp PM, Eaves AC, Humphries RK. 1991. Mechanisms that regulate the cell cycle status of very primitive hematopoietic cells in long-term human marrow cultures. II. Analysis of positive and negative regulators produced by stromal cells within the adherent layer. Blood 78:110-117.
11. Fortunel N, Batard P, Hatzfeld A, Monier MN, Panterne B, Lebkowski J, Hatzfeld J. 1998. High proliferative potential-quiescent cells: a working model to study primitive quiescent hematopoietic cells. J Cell Sci 111:1867-1875.
12. Fortunel N, Hatzfeld J, Aoustin L, Batard P, Ducos K, Monier MN, Hatzfeld A. 2000. Specific dose-response effects of TGF-β1 on developmentally distinct hematopoietic stem/progenitor cells from human umbilical cord blood. Hemat J 1:133-142.
13. Gleizes PE, Munger JS, Nunes I, Harpel JG, Mazzieri R, Noguera I, Rifkin DB. 1997. TGF-β latency: biological significance and mechanisms of activation. Stem Cells 15:190-197.
14. + cells isolated in subcompartments of the G0/G1 phase of the cell cycle. Blood 90:4384-4393.
15. INK4d, a p16-related inhibitor specific to CDK6 and CDK4. Mol Biol Cell 7:57-70.
16. Hannon GJ, Beach D. 1994. p15INK4B is a potential effector of TGF-β-induced cell cycle arrest. Nature 371:257-261.
17. Harper JW, Adami GR, Wei N, Keyomarsi K, Elledge SJ. 1993. The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases. Cell 75:805-816.
18. Harper JW, Elledge SJ. 1996. Cdk inhibitors in development and cancer. Curr Opin Genet Dev 6:56-64.
19. Hatzfeld A, Batard P, Panterne B, Taieb F, Hatzfeld J. 1996. Increased stable retroviral gene transfer in early hematopoietic progenitors released from quiescence. Hum Gene Ther 7:207-213.
20. Hatzfeld J, Li ML, Brown EL, Sookdeo H, Levesque JP, O'Toole T, Gurney C, Clark SC, Hatzfeld A. 1991. Release of early human hematopoietic progenitors from quiescence by antisense transforming growth factor β1 or Rb oligonucleotides. J Exp Med 174:925-929.
21. Jacobsen SE, Keller JR, Ruscetti FW, Kondaiah P, Roberts AB, Falk LA. 1991a. Bidirectional effects of transforming growth factor-β (TGF-β) on colony-stimulating factor-induced human myelopoiesis in vitro: differential effects of distinct TGF-β isoforms. Blood 78: 2239-2247.
22. Jacobsen SE, Ruscetti FW, Dubois CM, Lee J, Boone TC, Keller JR. 1991b. Transforming growth factor-β trans-modulates the expression of colony stimulating factor receptors on murine hematopoietic progenitor cell lines. Blood 77:1706-1716.
23. Junker U, Knoefel B, Nuske K, Rebstock K, Steiner T, Wunderlich H, Junker K, Reinhold D. 1996. Transforming growth factor-β1 is significantly elevated in plasma of patients suffering from renal cell carcinoma. Cytokine 8:794-798.
24. Li CY, Suardet L, Little JB. 1995. Potential role of WAF1/Cip1/p21 as a mediator of TGF-β cytoinhibitory effect. J Biol Chem 270:4971-4974.
25. Luo Y, Hurwitz J, Massagué J. 1995. Cell-cycle inhibition by independent CDK and PCNA binding domains in p21Cip1. Nature 375: 159-161.
26. Massagué J. 1990. Transforming growth factor β family. Annu Rev Cell Biol 6:597-641.
27. McNiece IK, Bertoncello I, Keller JR, Ruscetti FW, Hartley CA, Zsebo KM. 1992. Transforming growth factor-β inhibits the action of stem cell factor on mouse and human hematopoietic progenitors. Int J Cell Cloning 10:80-86.
28. Ohta M, Greenberger JS, Anklesaria P, Bassols A, Massagué J. 1987. Two forms of transforming growth factor-β distinguished by multi-potential haematopoietic progenitor cells. Nature 329:539-541.
29. Ottmann OG, Pelus LM. 1988. Differential proliferative effects of Transforming growth factor-β on human hematopoietic progenitor cells. J Immunol 140:2661-2665.
30. Panterne B, Hatzfeld A, Sansilvestri P, Cardoso AA, Monier MN, Batard P, Hatzfeld J. 1996. IL-3, GM-CSF and CSF-I modulate c-fms mRNA more rapidly in human early monocytic progenitors than in mature or transformed monocytic cells. J Cell Sci 109:1795-1801.
31. Panterne B, Zhou YQ, Hatzfeld J, Li ML, Levesque JP, Clark SC, Hatzfeld A. 1993. CSF-1 control of C-FMS expression in normal human bone marrow progenitors. J Cell Physiol 155:282-289.
32. Polyak K, Lee MH, Erdjument-Bromage H, Koff A, Roberts JM, Tempst P, Massagué J. 1994. Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals. Cell 78:59-66.
33. Polyak K. 1996. Negative regulation of cell growth by TGF-β. Biochim Biophys Acta 1242:185-199.
34. Reynisdottir I, Polyak K, Iavarone A, Massagué J. 1995. Kip/Cip and INK4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-β. Genes Dev 9:1831-1845.
35. Roberts AB, Flanders KC, Heine UI, Jakowlew S, Kondaiah P, Kim SJ, Sporn MB. 1990. Transforming growth factor-β: multifunctional regulator of differentiation and development. Philos Trans R Soc Lond B Biol Sci 327:145-154.
36. high cells in which transforming growth factor-β (TGF-β) downmodulates c-kit and KIT low cells in which anti-TGF-β upmodulates c-kit. Blood 86:1729-1735.
37. Serrano M, Hannon GJ, Beach D. 1993. A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4 Nature 366:704-707.
38. Sherr CJ, Roberts JM. 1995. Inhibitors of mammalian G1 cyclin-dependent kinases. Genes Dev 9:1149-1163.
39. Sing GK, Keller JR, Ellingsworth LR, Ruscetti FW. 1988. Transforming growth factor β selectively inhibits normal and leukemic human bone marrow cell growth in vitro. Blood 72:1504-1511.
40. Steinman RA, Hoffman B, Iro A, Guillouf C, Liebermann DA, El-Houseini ME. 1994. Induction of p21(WAF1/CIP1) during differentiation. Oncogene 9:3389-3396.
41. Steinman RA, Huang J, Yaroslavskiy B, Goff JP, Ball ED, Nguyen A. 1998. Regulation of p21(WAF1) expression during normal myeloid differentiation. Blood 91:4531-4542.
42. Taniguchi T, Endo H, Chikatsu N, Uchimaru K, Asano S, Fujita T, Nakahata T, Motokura T. 1999. Expression of p21(cip1/waf1/Sdi1) and p27(Kip1) cyclin-dependant kinase inhibitors during human hematopoiesis. Blood 12:4167-4178.
43. Zhang W, Grasso L, McClain CD, Gambel AM, Cha Y, Travail S, Deisseroth AB, Mercer WE. 1995. p53-independent induction of WAF1/CIP1 in human leukemia cells is correlated with growth arrest accompanying monocyte/macrophage differentiation. Cancer Res 55:668-674.