Cannabinoid and heroin activation of mesolimbic dopamine transmission by a common μ1 opioid receptor mechanism

Science

Volumn 276, Issue 5321, 1997, Pages 2048-2050

  Tanda, Gianluigi ^a   Pontieri, Francesco E ^a,b   Di Chiara, Gaetano ^a  

^a UNIVERSITY OF CAGLIARI   (Italy)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

2,3 DIHYDRO 5 METHYL 3 (MORPHOLINOMETHYL) 6 (1 NAPHTHOYL)PYRROLO[1,2,3 DE][1,4]BENZOXAZINE; CANNABINOID; CANNABIS; DIAMORPHINE; MU OPIATE RECEPTOR; NALOXONE; RIMONABANT;

ARTICLE; CANNABIS ADDICTION; DOPAMINERGIC TRANSMISSION; LIMBIC CORTEX; MICRODIALYSIS; PRIORITY JOURNAL; TEGMENTUM;

ANIMALS; DOPAMINE; HEROIN; MALE; MICRODIALYSIS; MORPHOLINES; NALOXONE; NAPHTHALENES; NARCOTIC ANTAGONISTS; NUCLEUS ACCUMBENS; PIPERIDINES; PYRAZOLES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, CANNABINOID; RECEPTORS, DRUG; RECEPTORS, OPIOID, MU; TETRAHYDROCANNABINOL;

EID: 0030761521     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.276.5321.2048     Document Type: Article

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31. We thank R. Frau, P. Loddo, and A. Marchioni for expert assistance, and P. Soubriè for providing SR141716A. Supported by funds from CNR, "Disease Factors" project, from Ministero Ricerca Scientifica and from European Community project BMH 4-CT 96-0203.