Breaking through to the other side: Silencers and barriers

Current Opinion in Genetics and Development

Volumn 12, Issue 2, 2002, Pages 188-192

  Dhillon, Namrita ^a   Kamakaka, Rohinton T ^a  

^a EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; DNA; HISTONE; HISTONE ACETYLTRANSFERASE;

ACETYLATION; CELL CYCLE; CELL CYCLE S PHASE; CELL NUCLEUS; DNA REPLICATION; GENE SILENCING; GENETIC TRANSCRIPTION; HETEROCHROMATIN; HUMAN; METHYLATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; REVIEW; THEORETICAL MODEL; YEAST;

EID: 0036532119     PISSN: 0959437X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0959-437X(02)00285-X     Document Type: Review

References (44)

1. Silencers and locus control regions: Opposite sides of the same coin
2. Role of interactions between the origin recognition complex and SIR1 in transcriptional silencing
3. A region of the Sir1 protein dedicated to recognition of a silencer and required for interaction with the Orc1 protein in saccharomyces cerevisiae
4. Cooperation at a distance between silencers and protosilencers at the yeast HML locus
5. Yeast heterochromatin is a dynamic structure that requires silencers continuously
6. Common themes in mechanisms of gene silencing
7. A histone variant, Htz1p, and a Sir1p-like protein, Esc2p, mediate silencing at HMR
8. Silencers and domains of generalized repression
9. The boundaries of the silenced HMR domain in Saccharomyces cerevisiae
10. Promoter-specific binding of Rap1 revealed by genome-wide maps of protein-DNA association
11. The Sir1 protein's association with a silenced chromosome domain
12. Silent domains are assembled continuously from the telomere and are defined by promoter distance and strength, and by SIR3 dosage
13. Silent information regulator protein complexes in Saccharomyces cerevisiae: A SIR2/SIR4 complex and evidence for a regulatory domain in SIR4 that inhibits its interaction with SIR3
14. Sir2p exists in two nucleosome-binding complexes with distinct deacetylase activities
15. Distinct protein interaction domains and protein spreading in a complex centromere
16. Localization and properties of a silencing element near the mat3-M mating-type cassette of Schizosaccharomyces pombe
17. A recombinationally repressed region between mat2 and mat3 loci shares homology to centromeric repeats and regulates directionality of mating- type switching in fission yeast
18. Transitions in distinct histone H3 methylation patterns at the heterochromatin domain boundaries
19. Histone deacetylase homologs regulate epigenetic inheritance of transcriptional silencing and chromosome segregation in fission yeast
20. Role of histone H3 lysine 9 methylation in epigenetic control of heterochromatin assembly
21. Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domain
22. Role of DNA replication in the repression of silent mating type loci in yeast
23. Targeting of SIR1 protein establishes transcriptional silencing at HM loci and telomeres in yeast
24. The origin recognition complex, SIR1, and the S phase requirement for silencing
25. DNA replication-independent silencing in S. cerevisiae
26. Establishment of transcriptional silencing in the absence of DNA replication
27. De novo nucleosome assembly: New pieces in an old puzzle
28. Postreplicative chromatin assembly by Drosophila and human chromatin assembly factor 1
29. Role of histone acetylation in the assembly and modulation of chromatin structures
30. PCNA connects DNA replication to epigenetic inheritance in yeast
31. Yeast histone deposition protein Asf1p requires Hir proteins and PCNA for heterochromatic silencing
32. The Isw2 chromatin remodeling complex represses early meiotic genes upon recruitment by Ume6p
33. SIR2 and SIR4 interactions differ in core and extended telomeric heterochromatin in yeast
34. Transitions in histone acetylation reveal boundaries of three separately regulated neighboring loci
35. UASrpg can function as a heterochromatin boundary element in yeast
36. Cohabitation of insulators and silencing elements in yeast subtelomeric regions
37. An activation-independent role of transcription factors in insulator function
38. Limitations of silencing at native yeast telomeres
39. RNA polymerase III and RNA polymerase II promoter complexes are heterochromatin barriers in Saccharomyces cerevisiae
40. The yeast HML I silencer defines a heterochromatin domain boundary by directional establishment of silencing
41. Nucleosome structure of the yeast CHA1 promoter: Analysis of activation- dependent chromatin remodeling of an RNA-polymerase-II-transcribed gene in TBP and RNA pol II mutants defective in vivo in response to acidic activators
42. Correlation between histone lysine methylation and developmental changes at the chicken beta-globin locus
43. Long-range nucleosome ordering is associated with gene silencing in Drosophila melanogaster pericentric heterochromatin