Death Domain Mutagenesis of KILLER/DR5 Reveals Residues Critical for Apoptotic Signaling

Journal of Biological Chemistry

Volumn 276, Issue 18, 2001, Pages 14939-14945

  McDonald III, E Robert ^b   Chui, Patricia C ^b   Martelli, Peter F ^b   Dicker, David T ^b   El Deiry, Wafik S ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CONSERVATION; DRUG THERAPY; HYDROPHOBICITY; MUTAGENESIS; TUMORS;

APOPTOTIC SIGNALLING;

BIOCHEMISTRY;

FAS ANTIGEN; FAS ASSOCIATED DEATH DOMAIN PROTEIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN KILLER; RECEPTOR PROTEIN; TUMOR NECROSIS FACTOR RECEPTOR 1; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; UNCLASSIFIED DRUG; TNFRSF10B PROTEIN, HUMAN; TUMOR NECROSIS FACTOR RECEPTOR; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND RECEPTOR;

ALPHA HELIX; AMINO ACID SEQUENCE; APOPTOSIS; ARTICLE; CELL AGGREGATION; CELL DEATH; CYTOTOXICITY; HUMAN; HUMAN CELL; MOLECULAR STABILITY; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; STRUCTURE ACTIVITY RELATION; CELL LINE; CHEMISTRY; GENETICS; MOLECULAR GENETICS; MUTAGENESIS; PHYSIOLOGY; SEQUENCE HOMOLOGY;

AMINO ACID SEQUENCE; APOPTOSIS; CELL LINE; HUMANS; MOLECULAR SEQUENCE DATA; MUTAGENESIS; RECEPTORS, TNF-RELATED APOPTOSIS-INDUCING LIGAND; RECEPTORS, TUMOR NECROSIS FACTOR; SEQUENCE HOMOLOGY, AMINO ACID; SIGNAL TRANSDUCTION;

EID: 0035805527     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M100399200     Document Type: Article

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