메뉴 건너뛰기




Volumn 4, Issue 1, 1998, Pages 251-259

Bypass of abnormal MDM2 inhibition of p53-dependent growth suppression

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE; ONCOPROTEIN; PROTEIN P21; PROTEIN P53; RETINOBLASTOMA PROTEIN; THYMIDINE; TRITIUM;

EID: 0031930154     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (32)

References (42)
  • 1
    • 0030941458 scopus 로고    scopus 로고
    • p53, the cellular gatekeeper for growth and division
    • Levine, A. J. p53, the cellular gatekeeper for growth and division. Cell, 88: 323-331, 1997.
    • (1997) Cell , vol.88 , pp. 323-331
    • Levine, A.J.1
  • 2
    • 0028231586 scopus 로고
    • Induction of chemosensitivity in human lung cancer cells in vivo by adenovirus-mediated transfer of the wild-type p53 gene
    • Fujiwara, T., Grimm, E. A., Mukhopadhyay, T., Zhang, W-W., Owen-Schaub, L. B., and Roth, J. A. Induction of chemosensitivity in human lung cancer cells in vivo by adenovirus-mediated transfer of the wild-type p53 gene. Cancer Res., 54: 2287-2291, 1994.
    • (1994) Cancer Res. , vol.54 , pp. 2287-2291
    • Fujiwara, T.1    Grimm, E.A.2    Mukhopadhyay, T.3    Zhang, W.-W.4    Owen-Schaub, L.B.5    Roth, J.A.6
  • 3
    • 0029832231 scopus 로고    scopus 로고
    • In vitro evaluation of a p53-expressing adenovirus as an anti-cancer drug
    • Blagosklonny, M. V., and El-Deiry, W. S. In vitro evaluation of a p53-expressing adenovirus as an anti-cancer drug. Int. J. Cancer, 67: 386-392, 1996.
    • (1996) Int. J. Cancer , vol.67 , pp. 386-392
    • Blagosklonny, M.V.1    El-Deiry, W.S.2
  • 6
    • 0023339504 scopus 로고
    • Molecular analysis and chromosomal mapping of amplified genes isolated from a transformed mouse 3T3 cell line
    • Cahilly-Snyder, L., Yang-Feng, T., Francke, U., and George, D. L. Molecular analysis and chromosomal mapping of amplified genes isolated from a transformed mouse 3T3 cell line. Somatic Cell Mol. Genet., 13: 235-244, 1987.
    • (1987) Somatic Cell Mol. Genet. , vol.13 , pp. 235-244
    • Cahilly-Snyder, L.1    Yang-Feng, T.2    Francke, U.3    George, D.L.4
  • 8
    • 0026649648 scopus 로고
    • The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation
    • Momand, J., Zambetti, G. P., Olson, D. C., George, D., and Levine, A. J. The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation. Cell, 69: 1237-1245, 1992.
    • (1992) Cell , vol.69 , pp. 1237-1245
    • Momand, J.1    Zambetti, G.P.2    Olson, D.C.3    George, D.4    Levine, A.J.5
  • 9
    • 0029913730 scopus 로고    scopus 로고
    • 1 arrest and apoptosis functions of the p53 tumor suppressor protein
    • 1 arrest and apoptosis functions of the p53 tumor suppressor protein. Mol. Cell. Biol., 16: 2445-2452, 1996.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 2445-2452
    • Chen, J.1    Wu, X.2    Lin, J.3    Levine, A.J.4
  • 10
    • 0029985647 scopus 로고    scopus 로고
    • Cell type-specific inhibition of p53-mediated apoptosis by mdm2
    • Haupt, Y., Barak, Y., and Oren, M. Cell type-specific inhibition of p53-mediated apoptosis by mdm2. EMBO J., 15: 1596-1606, 1996.
    • (1996) EMBO J. , vol.15 , pp. 1596-1606
    • Haupt, Y.1    Barak, Y.2    Oren, M.3
  • 11
    • 0027244853 scopus 로고
    • The p53-mdm-2 autoregulatory feedback loop
    • Wu, X., Bayle, J. H., Olson, D., and Levine, A. J. The p53-mdm-2 autoregulatory feedback loop. Genes Dev., 7: 1126-1132, 1993.
    • (1993) Genes Dev. , vol.7 , pp. 1126-1132
    • Wu, X.1    Bayle, J.H.2    Olson, D.3    Levine, A.J.4
  • 12
    • 0028834902 scopus 로고
    • Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53
    • Jones, S. N., Roe, A. E., Donehower, L. A., and Bradley, A. Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53. Nature (Lond.), 378: 206-208, 1995.
    • (1995) Nature (Lond.) , vol.378 , pp. 206-208
    • Jones, S.N.1    Roe, A.E.2    Donehower, L.A.3    Bradley, A.4
  • 13
    • 0028823020 scopus 로고
    • Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53
    • Montes de Oca Luna, R., Wagner, D. S., and Lozano, G. Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53. Nature (Lond.), 378: 203-206, 1995.
    • (1995) Nature (Lond.) , vol.378 , pp. 203-206
    • Montes De Oca Luna, R.1    Wagner, D.S.2    Lozano, G.3
  • 14
    • 0027956208 scopus 로고
    • Enhanced translation: A novel mechanism of mdm2 oncogene overexpression identified in human tumor cells
    • Landers, J. E., Haines, D. S., Strauss, J. F., III, and George, D. L. Enhanced translation: a novel mechanism of mdm2 oncogene overexpression identified in human tumor cells. Oncogene, 9: 2745-2750, 1994.
    • (1994) Oncogene , vol.9 , pp. 2745-2750
    • Landers, J.E.1    Haines, D.S.2    Strauss III, J.F.3    George, D.L.4
  • 15
  • 17
    • 0027196974 scopus 로고
    • Amplification and overexpression of the MDM2 gene in a subset of human malignant gliomas without p53 mutations
    • Reifenberger, G., Liu, L., Ichimura, K., Schmidt, E. E., and Collins, V. P. Amplification and overexpression of the MDM2 gene in a subset of human malignant gliomas without p53 mutations. Cancer Res., 53: 2736-2739, 1993.
    • (1993) Cancer Res. , vol.53 , pp. 2736-2739
    • Reifenberger, G.1    Liu, L.2    Ichimura, K.3    Schmidt, E.E.4    Collins, V.P.5
  • 19
    • 0028081261 scopus 로고
    • The MDM2 oncogene overexpression in chronic lymphocytic leukemia and low-grade lymphoma of B-cell origin
    • Watanabe, T., Hotta, T., Ichikawa, A., Kinoshita, T., Nagai, H., Uchida, T., Murate, T., and Saito, H. The MDM2 oncogene overexpression in chronic lymphocytic leukemia and low-grade lymphoma of B-cell origin. Blood, 84: 3158-3165, 1994.
    • (1994) Blood , vol.84 , pp. 3158-3165
    • Watanabe, T.1    Hotta, T.2    Ichikawa, A.3    Kinoshita, T.4    Nagai, H.5    Uchida, T.6    Murate, T.7    Saito, H.8
  • 20
    • 0029033840 scopus 로고
    • p53 mutation, murine double minute 2 amplification, and human papillomavirus infection are frequently involved but not associated with each other in esophageal squamous cell carcinoma
    • Shibagaki, I., Tanaka, H., Shimada, Y., Wagata, T., Ikenaga, M., Imamura, M., and Ishizaki, K. p53 mutation, murine double minute 2 amplification, and human papillomavirus infection are frequently involved but not associated with each other in esophageal squamous cell carcinoma. Clin. Cancer Res., 1: 769-773, 1995.
    • (1995) Clin. Cancer Res. , vol.1 , pp. 769-773
    • Shibagaki, I.1    Tanaka, H.2    Shimada, Y.3    Wagata, T.4    Ikenaga, M.5    Imamura, M.6    Ishizaki, K.7
  • 21
    • 0026669469 scopus 로고
    • p53 function and dysfunction
    • Vogelstein, B., and Kinzler, K. W. p53 function and dysfunction. Cell, 70: 523-526, 1992.
    • (1992) Cell , vol.70 , pp. 523-526
    • Vogelstein, B.1    Kinzler, K.W.2
  • 22
    • 0025853776 scopus 로고
    • Tumorigenic potential associated with enhanced expression of a gene that is amplified in a mouse tumor cell line
    • Fakharzadeh, S. S., Trusko, S. P., and George, D. L. Tumorigenic potential associated with enhanced expression of a gene that is amplified in a mouse tumor cell line. EMBO J., 10: 1565-1569, 1991.
    • (1991) EMBO J. , vol.10 , pp. 1565-1569
    • Fakharzadeh, S.S.1    Trusko, S.P.2    George, D.L.3
  • 23
    • 0027498314 scopus 로고
    • The mdm-2 oncogene can overcome wild-type p53 suppression of transformed cell growth
    • Finlay, C. A. The mdm-2 oncogene can overcome wild-type p53 suppression of transformed cell growth. Mol. Cell. Biol., 13: 301-306, 1993.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 301-306
    • Finlay, C.A.1
  • 26
    • 0029824669 scopus 로고    scopus 로고
    • Alternatively spliced mdm2 transcripts with loss of p53 binding domain sequences: Transforming ability and frequent detection in human cancer
    • Sigalas, I., Calvert, A. H., Anderson, J. J., Neal, D. E., and Lunec, J. Alternatively spliced mdm2 transcripts with loss of p53 binding domain sequences: transforming ability and frequent detection in human cancer. Nat. Med., 2: 912-917, 1996.
    • (1996) Nat. Med. , vol.2 , pp. 912-917
    • Sigalas, I.1    Calvert, A.H.2    Anderson, J.J.3    Neal, D.E.4    Lunec, J.5
  • 28
    • 0029849620 scopus 로고    scopus 로고
    • Cancer cell cycles
    • Washington DC
    • Sherr, C. J. Cancer cell cycles. Science (Washington DC), 274: 1672-1677, 1996.
    • (1996) Science , vol.274 , pp. 1672-1677
    • Sherr, C.J.1
  • 29
    • 0028821895 scopus 로고
    • Effects of a recombinant adenovirus expressing WAF1/CIP1 on cell growth, cell cycle, and apoptosis
    • Katayose, D., Wersto, R., Cowan, K. H., and Seth, P. Effects of a recombinant adenovirus expressing WAF1/CIP1 on cell growth, cell cycle, and apoptosis. Cell Growth Differ., 6: 1207-1212, 1995.
    • (1995) Cell Growth Differ. , vol.6 , pp. 1207-1212
    • Katayose, D.1    Wersto, R.2    Cowan, K.H.3    Seth, P.4
  • 30
    • 0028820762 scopus 로고
    • The p21 cyclin-dependent kinase inhibitor suppresses tumorigenicity in vivo
    • Yang, Z-Y., Perkins, N. D., Ohno, T., Nabel, E. G., and Nabel, G. J. The p21 cyclin-dependent kinase inhibitor suppresses tumorigenicity in vivo. Nat. Med., 1: 1052-1056, 1995.
    • (1995) Nat. Med. , vol.1 , pp. 1052-1056
    • Yang, Z.-Y.1    Perkins, N.D.2    Ohno, T.3    Nabel, E.G.4    Nabel, G.J.5
  • 32
    • 0030614514 scopus 로고    scopus 로고
    • WAF1/CIP1, Rb, and c-myc signaling in phorbol ester-resistant cancer cells
    • WAF1/CIP1, Rb, and c-myc signaling in phorbol ester-resistant cancer cells. Cancer Res., 57: 320-325, 1997.
    • (1997) Cancer Res. , vol.57 , pp. 320-325
    • Blagosklonny, M.V.1    Prabhu, N.S.2    El-Deiry, W.S.3
  • 34
    • 0028147405 scopus 로고
    • Physical and functional interaction between wild-type p53 and mdm2 proteins
    • Haines, D. S., Landers, J. E., Engle, L. J., and George, D. L. Physical and functional interaction between wild-type p53 and mdm2 proteins. Mol. Cell. Biol., 14: 1171-1178, 1994.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 1171-1178
    • Haines, D.S.1    Landers, J.E.2    Engle, L.J.3    George, D.L.4
  • 35
    • 0030795068 scopus 로고    scopus 로고
    • Translational enhancement of mdm2 oncogene expression in human tumor cells containing a stabilized wild-type p53 protein
    • Landers, J. E., Cassel, S. L., and George, D. L. Translational enhancement of mdm2 oncogene expression in human tumor cells containing a stabilized wild-type p53 protein. Cancer Res., 57: 3562-3568, 1997.
    • (1997) Cancer Res. , vol.57 , pp. 3562-3568
    • Landers, J.E.1    Cassel, S.L.2    George, D.L.3
  • 36
    • 0029033861 scopus 로고
    • The retinoblastoma protein and cell cycle control
    • Weinberg, RA. The retinoblastoma protein and cell cycle control. Cell, 81: 323-330, 1995.
    • (1995) Cell , vol.81 , pp. 323-330
    • Weinberg, R.A.1
  • 38
    • 0029863840 scopus 로고    scopus 로고
    • Altered cell cycle kinetics, gene expression, and G1 restriction point regulation in Rb-deficient fibroblasts
    • Herrera, R. E., Sah, V. P., Williams, B. O., Makela, T. P., Weinberg, R. A., and Jacks, T. Altered cell cycle kinetics, gene expression, and G1 restriction point regulation in Rb-deficient fibroblasts. Mol. Cell. Biol., 16: 2402-2407, 1996.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 2402-2407
    • Herrera, R.E.1    Sah, V.P.2    Williams, B.O.3    Makela, T.P.4    Weinberg, R.A.5    Jacks, T.6
  • 39
    • 0028973212 scopus 로고
    • WAF1/CIP1 induces growth arrest, giant cell formation and apoptosis in human breast carcinoma cell lines
    • WAF1/CIP1 induces growth arrest, giant cell formation and apoptosis in human breast carcinoma cell lines. Oncogene, 11: 1899-1905, 1995.
    • (1995) Oncogene , vol.11 , pp. 1899-1905
    • Sheikh, M.S.1    Rochefort, H.2    Garcia, M.3
  • 41
    • 0030575937 scopus 로고    scopus 로고
    • Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain
    • Washington DC
    • Kussie, P. H., Gorina, S., Marechal, V., Elenbaas, B., Moreau, J., Levine, A. J., and Pavletich, N. P. Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain. Science (Washington DC), 274: 948-953, 1996.
    • (1996) Science , vol.274 , pp. 948-953
    • Kussie, P.H.1    Gorina, S.2    Marechal, V.3    Elenbaas, B.4    Moreau, J.5    Levine, A.J.6    Pavletich, N.P.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.