Insulin-induced Drosophila S6 kinase activation requires phosphoinositide 3-kinase and protein kinase B

Biochemical Journal

Volumn 374, Issue 2, 2003, Pages 297-306

  Lizcano, Jose M ^a   Alrubaie, Saif ^b   Kieloch, Agnieszka ^a   Deak, Maria ^a   Leevers, Sally J ^b   Alessi, Dario R ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

^b IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

Author keywords

Drosophila; Insulin signalling; Phosphatase and tensin homologue deleted on chromosome 10 (PTEN); Phosphoinositide 3 kinase (PI3K); Protein kinase B (PKB); S6 kinase (S6K)

Indexed keywords

CELLS; CHROMOSOMES; GROWTH KINETICS; INSULIN;

CELL GROWTH;

ENZYME KINETICS;

2 MORPHOLINO 8 PHENYLCHROMONE; AMINO ACID; DOUBLE STRANDED RNA; INSULIN; ISOENZYME; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; RAPAMYCIN; S6 KINASE; UNCLASSIFIED DRUG; WORTMANNIN;

ARTICLE; CONTROLLED STUDY; DROSOPHILA; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INDUCTION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; HORMONE ACTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; AMINO ACID SEQUENCE; AMINO ACIDS; ANDROSTADIENES; ANIMALS; CELL LINE; CHROMONES; DROSOPHILA PROTEINS; ENZYME ACTIVATION; ENZYME INDUCTION; ENZYME INHIBITORS; INSULIN; MOLECULAR SEQUENCE DATA; MORPHOLINES; PEPTIDES; PHOSPHORIC MONOESTER HYDROLASES; PRECIPITIN TESTS; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; PTEN PHOSPHOHYDROLASE; RIBOSOMAL PROTEIN S6 KINASES; RNA, DOUBLE-STRANDED; RNA, SMALL INTERFERING; TUMOR SUPPRESSOR PROTEINS;

MAMMALIA;

EID: 0041469795     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20030577     Document Type: Article

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