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Volumn 12, Issue 22, 2002, Pages

Growth signaling: TSC takes its place

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALIA;

EID: 0037137380     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-9822(02)01294-0     Document Type: Review
Times cited : (74)

References (20)
  • 1
    • 0036778129 scopus 로고    scopus 로고
    • Why size matters: Altering cell size
    • Saucedo, L. and Edgar, B. (2002). Why size matters: Altering cell size. Curr. Opin. Genet. Dev. 12, 565-571.
    • (2002) Curr. Opin. Genet. Dev. , vol.12 , pp. 565-571
    • Saucedo, L.1    Edgar, B.2
  • 2
    • 0036007421 scopus 로고    scopus 로고
    • Regulation of cell size in growth, development and human disease: PI 3-kinase, PKB and S6 kinase
    • Kozma, S.C. and Thomas, G. (2002). Regulation of cell size in growth, development and human disease: PI 3-kinase, PKB and S6 kinase. Bioessays 24, 65-71.
    • (2002) Bioessays , vol.24 , pp. 65-71
    • Kozma, S.C.1    Thomas, G.2
  • 3
    • 0033582748 scopus 로고    scopus 로고
    • gigas, a Drosophila homolog of tuberous sclerosis gene product-2, regulates the cell cycle
    • Ito, N. and Rubin, G.M. (1999). gigas, a Drosophila homolog of tuberous sclerosis gene product-2, regulates the cell cycle. Cell 96, 529-539.
    • (1999) Cell , vol.96 , pp. 529-539
    • Ito, N.1    Rubin, G.M.2
  • 4
    • 0034982971 scopus 로고    scopus 로고
    • TSC1 and TSC2 tumor suppressors antagonize insulin signaling in cell growth
    • Gao, X. and Pan, D. (2001). TSC1 and TSC2 tumor suppressors antagonize insulin signaling in cell growth. Genes Dev. 15, 1383-1392.
    • (2001) Genes Dev. , vol.15 , pp. 1383-1392
    • Gao, X.1    Pan, D.2
  • 5
    • 0035805162 scopus 로고    scopus 로고
    • Drosophila Tsc1 functions with Tsc2 to antagonize insulin signaling in regulating cell growth, cell proliferation, and organ size
    • Potter, C.J., Huang, H. and Xu, T. (2001). Drosophila Tsc1 functions with Tsc2 to antagonize insulin signaling in regulating cell growth, cell proliferation, and organ size. Cell 105, 357-368.
    • (2001) Cell , vol.105 , pp. 357-368
    • Potter, C.J.1    Huang, H.2    Xu, T.3
  • 6
    • 0035805180 scopus 로고    scopus 로고
    • The Drosophila tuberous sclerosis complex gene homologs restrict cell growth and cell proliferation
    • Tapon, N., Ito, N., Dickson, B.J., Treisman, J.E. and Hariharan, I.K. (2001). The Drosophila tuberous sclerosis complex gene homologs restrict cell growth and cell proliferation. Cell 105, 345-355.
    • (2001) Cell , vol.105 , pp. 345-355
    • Tapon, N.1    Ito, N.2    Dickson, B.J.3    Treisman, J.E.4    Hariharan, I.K.5
  • 10
    • 0036713778 scopus 로고    scopus 로고
    • TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling
    • Inoki, K., Li, Y., Zhu, T., Wu, J. and Guan, K.L. (2002). TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling. Nat. Cell Biol. 4, 648-657.
    • (2002) Nat. Cell Biol. , vol.4 , pp. 648-657
    • Inoki, K.1    Li, Y.2    Zhu, T.3    Wu, J.4    Guan, K.L.5
  • 11
    • 0036501277 scopus 로고    scopus 로고
    • A mouse model of TSC1 reveals sex-dependent lethality from liver hemangiomas, and up-regulation of p70S6 kinase activity in Tsc1 null cells
    • Kwiatkowski, D.J., Zhang, H., Bandura, J.L., Heiberger, K.M., Glogauer, M., el-Hashemite, N. and Onda, H. (2002). A mouse model of TSC1 reveals sex-dependent lethality from liver hemangiomas, and up-regulation of p70S6 kinase activity in Tsc1 null cells. Hum. Mol. Genet. 11, 525-534.
    • (2002) Hum. Mol. Genet. , vol.11 , pp. 525-534
    • Kwiatkowski, D.J.1    Zhang, H.2    Bandura, J.L.3    Heiberger, K.M.4    Glogauer, M.5    El-Hashemite, N.6    Onda, H.7
  • 12
    • 0036342294 scopus 로고    scopus 로고
    • Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-kinase/Akt pathway
    • Manning, B.D., Tee, A.R., Logsdon, M.N., Blenis, J. and Cantley, L.C. (2002). Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-kinase/Akt pathway. Mol. Cell 10, 151-162.
    • (2002) Mol. Cell , vol.10 , pp. 151-162
    • Manning, B.D.1    Tee, A.R.2    Logsdon, M.N.3    Blenis, J.4    Cantley, L.C.5
  • 14
    • 0036714127 scopus 로고    scopus 로고
    • Akt regulates growth by directly phosphorylating Tsc2
    • Potter, C.J., Pedraza, L.G. and Xu, T. (2002). Akt regulates growth by directly phosphorylating Tsc2. Nat. Cell Biol. 4, 658-665.
    • (2002) Nat. Cell Biol. , vol.4 , pp. 658-665
    • Potter, C.J.1    Pedraza, L.G.2    Xu, T.3
  • 15
    • 0029828590 scopus 로고    scopus 로고
    • The principal rapamycin-sensitive p70s6k phosphorylation sites T229 and T389 are differentially regulated by rapamycin-insensitive kinase-kinases
    • Dennis, P.B., Pullen, N., Kozma, S.C. and Thomas, G. (1996). The principal rapamycin-sensitive p70s6k phosphorylation sites T229 and T389 are differentially regulated by rapamycin-insensitive kinase-kinases. Mol. Cell. Biol. 16, 6242-6251.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 6242-6251
    • Dennis, P.B.1    Pullen, N.2    Kozma, S.C.3    Thomas, G.4
  • 20
    • 0037108151 scopus 로고    scopus 로고
    • Lethality of Drosophila lacking TSC tumor suppressor function rescued by reducing dS6K signaling
    • in press
    • Radimerski, T., Montagne, J., Hemmings-Mieszczak, M. and Thomas, G. (2002). Lethality of Drosophila lacking TSC tumor suppressor function rescued by reducing dS6K signaling. Genes Dev. in press.
    • (2002) Genes Dev.
    • Radimerski, T.1    Montagne, J.2    Hemmings-Mieszczak, M.3    Thomas, G.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.