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Volumn 84, Issue 5, 2003, Pages 1287-1299

Natural variation of the nef gene in human immunodeficiency virus type 2 infections in Portugal

Author keywords

[No Author keywords available]

Indexed keywords

ANTIRETROVIRUS AGENT; CD4 ANTIGEN; NEF PROTEIN; PROLINE;

EID: 0037987789     PISSN: 00221317     EISSN: None     Source Type: Journal    
DOI: 10.1099/vir.0.18908-0     Document Type: Review
Times cited : (8)

References (78)
  • 2
    • 0034722743 scopus 로고    scopus 로고
    • Plasma viral load in HIV-1 and HIV-2 singly and dually infected individuals in Guinea-Bissau, West Africa: Significantly lower plasma virus set point in HIV-2 infection than in HIV-1 infection
    • Andersson, S., Norrgren, H., da Silva, Z., Biague, A., Bamba, S., Kwok, S., Christopherson, C., Biberfeld, G. & Albert, J. (2000). Plasma viral load in HIV-1 and HIV-2 singly and dually infected individuals in Guinea-Bissau, West Africa: significantly lower plasma virus set point in HIV-2 infection than in HIV-1 infection. Arch Intern Med 160, 3286-3293.
    • (2000) Arch. Intern. Med. , vol.160 , pp. 3286-3293
    • Andersson, S.1    Norrgren, H.2    da Silva, Z.3    Biague, A.4    Bamba, S.5    Kwok, S.6    Christopherson, C.7    Biberfeld, G.8    Albert, J.9
  • 3
    • 0034069264 scopus 로고    scopus 로고
    • Plasma RNA viral load predicts the rate of CD4 T cell decline and death in HIV-2-infected patients in West Africa
    • & 7 other authors
    • Ariyoshi, K., Jaffar, S., Alabi, A. & 7 other authors (2000). Plasma RNA viral load predicts the rate of CD4 T cell decline and death in HIV-2-infected patients in West Africa. AIDS 14, 339-344.
    • (2000) AIDS , vol.14 , pp. 339-344
    • Ariyoshi, K.1    Jaffar, S.2    Alabi, A.3
  • 4
    • 0031791917 scopus 로고    scopus 로고
    • Association of simian immunodeficiency virus Nef with the T-cell receptor (TCR) ζ chain leads to TCR down-modulation
    • Bell, I., Ashman, C., Maughan, J., Hooker, E., Cook, F. & Reinhart, T. A. (1998). Association of simian immunodeficiency virus Nef with the T-cell receptor (TCR) ζ chain leads to TCR down-modulation. J Gen Virol 79, 2717-2727.
    • (1998) J. Gen. Virol. , vol.79 , pp. 2717-2727
    • Bell, I.1    Ashman, C.2    Maughan, J.3    Hooker, E.4    Cook, F.5    Reinhart, T.A.6
  • 6
    • 0032195713 scopus 로고    scopus 로고
    • Low peripheral blood viral HIV-2 RNA in individuals with high CD4 percentage differentiates HIV-2 from HIV-1 infection
    • Berry, N. J., Ariyoshi, K., Jaffar, S., Sabally, S., Corrah, T., Tedder, R. & Whittle, H. (1998). Low peripheral blood viral HIV-2 RNA in individuals with high CD4 percentage differentiates HIV-2 from HIV-1 infection. J Hum Virol 1, 457-468.
    • (1998) J. Hum. Virol. , vol.1 , pp. 457-468
    • Berry, N.J.1    Ariyoshi, K.2    Jaffar, S.3    Sabally, S.4    Corrah, T.5    Tedder, R.6    Whittle, H.7
  • 7
    • 0035835504 scopus 로고    scopus 로고
    • Sequence specificity of the human immunodeficiency virus type 2 (HIV-2) long terminal repeat U3 region in vivo allows subtyping of the principal HIV-2 viral subtypes A and B
    • Berry, N. J., Ariyoshi, K., Balfe, P., Tedder, R. & Whittle, H. (2001). Sequence specificity of the human immunodeficiency virus type 2 (HIV-2) long terminal repeat U3 region in vivo allows subtyping of the principal HIV-2 viral subtypes A and B. AIDS Res Hum Retroviruses 17, 263-267.
    • (2001) AIDS Res. Hum. Retroviruses , vol.17 , pp. 263-267
    • Berry, N.J.1    Ariyoshi, K.2    Balfe, P.3    Tedder, R.4    Whittle, H.5
  • 8
    • 0036434962 scopus 로고    scopus 로고
    • Low level viremia and high CD4% predict normal survival in a cohort of HIV type 2-infected villagers
    • & 9 other authors
    • Berry, N. J., Jaffar, S., Schim van der Loeff, M. & 9 other authors (2002). Low level viremia and high CD4% predict normal survival in a cohort of HIV type 2-infected villagers. AIDS Res Hum Retroviruses 18, 1167-1173.
    • (2002) AIDS Res. Hum. Retroviruses , vol.18 , pp. 1167-1173
    • Berry, N.J.1    Jaffar, S.2    Schim van der Loeff, M.3
  • 9
    • 0035663379 scopus 로고    scopus 로고
    • Infection with HIV-2
    • Bock, P. J. & Markovitz, D. M. (2001). Infection with HIV-2. AIDS 15 (suppl. 5), S35-S45.
    • (2001) AIDS , vol.15 , Issue.SUPPL. 5
    • Bock, P.J.1    Markovitz, D.M.2
  • 12
    • 0033568211 scopus 로고    scopus 로고
    • SIV Nef protein utilizes both leucine- and tyrosine-based protein sorting pathways for down-regulation of CD4
    • Bresnahan, P. A., Yonemoto, W. & Greene, W. C. (1999). SIV Nef protein utilizes both leucine- and tyrosine-based protein sorting pathways for down-regulation of CD4. J Immunol 163, 2977-2981.
    • (1999) J. Immunol. , vol.163 , pp. 2977-2981
    • Bresnahan, P.A.1    Yonemoto, W.2    Greene, W.C.3
  • 13
    • 0033995168 scopus 로고    scopus 로고
    • Simian immunodeficiency virus containing mutations in N-terminal tyrosine residues and in the PxxP motif in Nef replicates efficiently in rhesus macaques
    • Carl, S., Iafrate, A. J., Lang, S., Stolte, N., Stahl-Hennig, C., Matz-Rensing, K., Fuchs, D., Skowronski, J. & Kirchhoff, F. (2000a). Simian immunodeficiency virus containing mutations in N-terminal tyrosine residues and in the PxxP motif in Nef replicates efficiently in rhesus macaques. J Virol 74, 4155-4164.
    • (2000) J. Virol. , vol.74 , pp. 4155-4164
    • Carl, S.1    Iafrate, A.J.2    Lang, S.3    Stolte, N.4    Stahl-Hennig, C.5    Matz-Rensing, K.6    Fuchs, D.7    Skowronski, J.8    Kirchhoff, F.9
  • 14
    • 0033954999 scopus 로고    scopus 로고
    • Partial 'repair' of defective nef genes in a long-term nonprogressor with human immunodeficiency type 1 infection
    • Carl, S., Daniels, R., Iafrate, A. J., Easterbrook, P., Greenough, T. C., Skowronski, J. & Kirchhoff, F. (2000b). Partial 'repair' of defective nef genes in a long-term nonprogressor with human immunodeficiency type 1 infection. J Infect Dis 181, 132-140.
    • (2000) J. Infect. Dis. , vol.181 , pp. 132-140
    • Carl, S.1    Daniels, R.2    Iafrate, A.J.3    Easterbrook, P.4    Greenough, T.C.5    Skowronski, J.6    Kirchhoff, F.7
  • 15
    • 0031001926 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 2 (HIV-2) seroprevalence and characterization of a distinct HIV-2 genetic subtype from the natural range of simian immunodeficiency virus-infected sooty mangabeys
    • & 9 other authors
    • Chen, Z., Luckay, A., Sodora, D. L. & 9 other authors (1997). Human immunodeficiency virus type 2 (HIV-2) seroprevalence and characterization of a distinct HIV-2 genetic subtype from the natural range of simian immunodeficiency virus-infected sooty mangabeys. J Virol 71, 3953-3960.
    • (1997) J. Virol. , vol.71 , pp. 3953-3960
    • Chen, Z.1    Luckay, A.2    Sodora, D.L.3
  • 16
    • 0033544383 scopus 로고    scopus 로고
    • The conserved core of human immunodeficiency virus type 1 Nef is essential for association with Lck and for enhanced viral replication in T-lymphocytes
    • Cheng, H., Hoxie, J. & Parks, W. P. (1999). The conserved core of human immunodeficiency virus type 1 Nef is essential for association with Lck and for enhanced viral replication in T-lymphocytes. Virology 264, 5-15.
    • (1999) Virology , vol.264 , pp. 5-15
    • Cheng, H.1    Hoxie, J.2    Parks, W.P.3
  • 17
    • 0028981753 scopus 로고
    • The peri-κB site mediates human immunodeficiency virus type 2 enhancer activation in monocytes but not in T cells
    • Clark, N. M., Hannibal, M. C. & Markovitz, D. M. (1995). The peri-κB site mediates human immunodeficiency virus type 2 enhancer activation in monocytes but not in T cells. J Virol 69, 4854-4862.
    • (1995) J. Virol. , vol.69 , pp. 4854-4862
    • Clark, N.M.1    Hannibal, M.C.2    Markovitz, D.M.3
  • 18
    • 0023052240 scopus 로고
    • Isolation of a new human retrovirus from West African patients with AIDS
    • & 9 other authors
    • Clavel, F., Guetard, D., Brun-Vezinet, F. & 9 other authors (1986). Isolation of a new human retrovirus from West African patients with AIDS. Science 233, 343-346.
    • (1986) Science , vol.233 , pp. 343-346
    • Clavel, F.1    Guetard, D.2    Brun-Vezinet, F.3
  • 19
    • 0031053503 scopus 로고    scopus 로고
    • Towards a consensus for a role of Nef in both viral replication and immunomodulation
    • Collette, Y. (1997). Towards a consensus for a role of Nef in both viral replication and immunomodulation. Res Virol 148, 23-30.
    • (1997) Res. Virol. , vol.148 , pp. 23-30
    • Collette, Y.1
  • 21
    • 0034635475 scopus 로고    scopus 로고
    • HIV-2 and SIV Nef proteins target different Src family SH3 domains than does HIV-1 Nef because of a triple amino acid substitution
    • Collette, Y., Arold, S., Picard, C., Janvier, K., Benichou, S., Benarous, R., Olive, D. & Dumas, C. (2000). HIV-2 and SIV Nef proteins target different Src family SH3 domains than does HIV-1 Nef because of a triple amino acid substitution. J Biol Chem 275, 4171-4176.
    • (2000) J. Biol. Chem. , vol.275 , pp. 4171-4176
    • Collette, Y.1    Arold, S.2    Picard, C.3    Janvier, K.4    Benichou, S.5    Benarous, R.6    Olive, D.7    Dumas, C.8
  • 22
    • 0032530773 scopus 로고    scopus 로고
    • Interaction of HIV-1 Nef with the cellular dileucine-based sorting pathway is required for CD4 down-regulation and optimal viral infectivity
    • Craig, H. M., Pandori, M. W. & Guatelli, J. C. (1998). Interaction of HIV-1 Nef with the cellular dileucine-based sorting pathway is required for CD4 down-regulation and optimal viral infectivity. Proc Natl Acad Sci U S A 95, 11229-11234.
    • (1998) Proc. Natl. Acad. Sci. U S A , vol.95 , pp. 11229-11234
    • Craig, H.M.1    Pandori, M.W.2    Guatelli, J.C.3
  • 23
    • 0028804160 scopus 로고
    • Genomic structure of an attenuated quasi species of HIV-1 from a blood transfusion donor and recipients
    • & other authors
    • Deacon, N. J., Tsykin, A., Solomon, A. & other authors (1995). Genomic structure of an attenuated quasi species of HIV-1 from a blood transfusion donor and recipients. Science 270, 988-991.
    • (1995) Science , vol.270 , pp. 988-991
    • Deacon, N.J.1    Tsykin, A.2    Solomon, A.3
  • 24
    • 0030612788 scopus 로고    scopus 로고
    • The N-terminal Arg-rich region of human immunodeficiency virus types 1 and 2 and simian immunodeficiency virus Nef is involved in RNA binding
    • Echarri, A., Gonzalez, M. E. & Carrasco, L. (1997). The N-terminal Arg-rich region of human immunodeficiency virus types 1 and 2 and simian immunodeficiency virus Nef is involved in RNA binding. Eur J Biochem 246, 38-44.
    • (1997) Eur. J. Biochem. , vol.246 , pp. 38-44
    • Echarri, A.1    Gonzalez, M.E.2    Carrasco, L.3
  • 25
    • 0036230879 scopus 로고    scopus 로고
    • Live and let die: Nef functions beyond HIV replication
    • Fackler, O. T. & Baur, A. S. (2002). Live and let die: Nef functions beyond HIV replication. Immunity 16, 493-497.
    • (2002) Immunity , vol.16 , pp. 493-497
    • Fackler, O.T.1    Baur, A.S.2
  • 26
    • 0035928809 scopus 로고    scopus 로고
    • A natural variability in the proline-rich motif of Nef modulates HIV-1 replication in primary T cells
    • & 9 other authors
    • Fackler, O. T., Wolf, D., Weber, H. O. & 9 other authors (2001). A natural variability in the proline-rich motif of Nef modulates HIV-1 replication in primary T cells. Curr Biol 11, 1294-1299.
    • (2001) Curr. Biol. , vol.11 , pp. 1294-1299
    • Fackler, O.T.1    Wolf, D.2    Weber, H.O.3
  • 27
    • 0024152983 scopus 로고
    • Phylogenies from molecular sequences: Inference and reliability
    • Felsenstein, J. (1989). Phylogenies from molecular sequences: inference and reliability. Annu Rev Genet 22, 521-565.
    • (1989) Annu. Rev. Genet. , vol.22 , pp. 521-565
    • Felsenstein, J.1
  • 29
    • 0028063444 scopus 로고
    • Genetic diversity of human immunodeficiency virus type 2: Evidence for distinct sequence subtypes with differences in virus biology
    • & 9 other authors
    • Gao, F., Yue, L., Robertson, D. L. & 9 other authors (1994). Genetic diversity of human immunodeficiency virus type 2: evidence for distinct sequence subtypes with differences in virus biology. J Virol 68, 7433-7447.
    • (1994) J. Virol. , vol.68 , pp. 7433-7447
    • Gao, F.1    Yue, L.2    Robertson, D.L.3
  • 31
    • 0035848864 scopus 로고    scopus 로고
    • HIV-1 Nef inhibits ASK1-dependent death signalling providing a potential mechanism for protecting the infected host cell
    • Geleziunas, R., Xu, W., Takeda, K., Ichijo, H. & Greene, W. C. (2001). HIV-1 Nef inhibits ASK1-dependent death signalling providing a potential mechanism for protecting the infected host cell. Nature 410, 834-838.
    • (2001) Nature , vol.410 , pp. 834-838
    • Geleziunas, R.1    Xu, W.2    Takeda, K.3    Ichijo, H.4    Greene, W.C.5
  • 32
    • 0034894379 scopus 로고    scopus 로고
    • Structure-function relationships in HIV-1 Nef
    • Geyer, M., Fackler, O. T. & Peterlin, B. M. (2001). Structure-function relationships in HIV-1 Nef. EMBO Rep 21, 580-585.
    • (2001) EMBO Rep. , vol.21 , pp. 580-585
    • Geyer, M.1    Fackler, O.T.2    Peterlin, B.M.3
  • 33
    • 0031668695 scopus 로고    scopus 로고
    • Mortality among human immunodeficiency virus type 2-positive villagers in rural Guinea-Bissau is correlated with viral genotype
    • Grassly, N. C., Xiang, Z., Ariyoshi, K., Aaby, P., Jensen, H., van der Loeff, M. S., Dias, F., Whittle, H. & Breuer, J. (1998). Mortality among human immunodeficiency virus type 2-positive villagers in rural Guinea-Bissau is correlated with viral genotype. J Virol 72, 7895-7899.
    • (1998) J. Virol. , vol.72 , pp. 7895-7899
    • Grassly, N.C.1    Xiang, Z.2    Ariyoshi, K.3    Aaby, P.4    Jensen, H.5    van der Loeff, M.S.6    Dias, F.7    Whittle, H.8    Breuer, J.9
  • 34
    • 0030684068 scopus 로고    scopus 로고
    • Co-localization of HIV-1 Nef with the AP-2 adaptor protein complex correlates with Nef-induced CD4 down-regulation
    • Greenberg, M. E., Bronson, S., Lock, M., Neumann, M., Pavlakils, G. N. & Skowronski, J. (1997). Co-localization of HIV-1 Nef with the AP-2 adaptor protein complex correlates with Nef-induced CD4 down-regulation. EMBO J 16, 6964-6976.
    • (1997) EMBO J. , vol.16 , pp. 6964-6976
    • Greenberg, M.E.1    Bronson, S.2    Lock, M.3    Neumann, M.4    Pavlakils, G.N.5    Skowronski, J.6
  • 35
    • 0032990431 scopus 로고    scopus 로고
    • Simian immunodeficiency virus and human immunodeficiency virus type 1 Nef protein show distinct patterns and mechanisms of Src kinase activation
    • Greenway, A. L., Dutartre, H., Allen, K., McPhee, D. A., Olive, D. & Collette, Y. (1999). Simian immunodeficiency virus and human immunodeficiency virus type 1 Nef protein show distinct patterns and mechanisms of Src kinase activation. J Virol 73, 6152-6158.
    • (1999) J. Virol. , vol.73 , pp. 6152-6158
    • Greenway, A.L.1    Dutartre, H.2    Allen, K.3    McPhee, D.A.4    Olive, D.5    Collette, Y.6
  • 36
    • 0032538278 scopus 로고    scopus 로고
    • Nef harbours a major determinant of pathogenicity for an AIDS-like disease induced by HIV-1 in transgenic mice
    • Hanna, Z., Kay, D. G., Rebai, N., Guimond, A., Jothy, S. & Jolicoeur, P. (1998). Nef harbours a major determinant of pathogenicity for an AIDS-like disease induced by HIV-1 in transgenic mice. Cell 95, 163-175.
    • (1998) Cell , vol.95 , pp. 163-175
    • Hanna, Z.1    Kay, D.G.2    Rebai, N.3    Guimond, A.4    Jothy, S.5    Jolicoeur, P.6
  • 37
    • 0034843329 scopus 로고    scopus 로고
    • The pathogenicity of human immunodeficiency virus (HIV) type 1 Nef in CD4C/HIV transgenic mice is abolished by mutation of its SH3-binding domain, and disease development is delayed in the absence of Hck
    • Hanna, Z., Wang, X., Kay, D. G., Poudrier, J., Lowell, C. & Jolicoeur, P. (2001). The pathogenicity of human immunodeficiency virus (HIV) type 1 Nef in CD4C/HIV transgenic mice is abolished by mutation of its SH3-binding domain, and disease development is delayed in the absence of Hck. J Virol 75, 9378-9392.
    • (2001) J. Virol. , vol.75 , pp. 9378-9392
    • Hanna, Z.1    Wang, X.2    Kay, D.G.3    Poudrier, J.4    Lowell, C.5    Jolicoeur, P.6
  • 38
    • 0029133326 scopus 로고
    • The role of myristoylation in the interactions between the human immunodeficiency virus type 1 Nef and cellular proteins
    • Harris, M. (1995). The role of myristoylation in the interactions between the human immunodeficiency virus type 1 Nef and cellular proteins. Biochem Soc Trans 23, 557-561.
    • (1995) Biochem. Soc. Trans. , vol.23 , pp. 557-561
    • Harris, M.1
  • 39
    • 0032938988 scopus 로고    scopus 로고
    • Genetic characterization of the nef gene from human immunodeficiency virus type 1 group M strains representing genetic subtypes A, B, C, E, F, G, and H
    • & 7 other authors
    • Jubler-Maurin, V., Saragosti, S., Perret, J.-L. & 7 other authors (1999). Genetic characterization of the nef gene from human immunodeficiency virus type 1 group M strains representing genetic subtypes A, B, C, E, F, G, and H. AIDS Res Hum Retroviruses 15, 23-32.
    • (1999) AIDS Res. Hum. Retroviruses , vol.15 , pp. 23-32
    • Jubler-Maurin, V.1    Saragosti, S.2    Perret, J.-L.3
  • 40
    • 0032551187 scopus 로고    scopus 로고
    • Nef proteins of distinct HIV-1 or -2 isolates differ in their binding properties for HCK: Isolation of a novel Nef binding factor with characteristics of an adaptor protein
    • Karn, T., Hock, B., Holtrich, U., Adamski, M., Strebhardt, K. & Rubsamen-Waigmann, H. (1998). Nef proteins of distinct HIV-1 or -2 isolates differ in their binding properties for HCK: isolation of a novel Nef binding factor with characteristics of an adaptor protein. Virology 246, 45-52.
    • (1998) Virology , vol.246 , pp. 45-52
    • Karn, T.1    Hock, B.2    Holtrich, U.3    Adamski, M.4    Strebhardt, K.5    Rubsamen-Waigmann, H.6
  • 42
    • 0031777959 scopus 로고    scopus 로고
    • Role of the SH3-ligand domain of simian immunodeficiency virus Nef in interaction with Nef-associated kinase and simian AIDS in rhesus macaques
    • Khan, I. H., Sawai, E. T., Antonio, E., Weber, C. J., Mandell, C. P., Montbriand, P. & Luciw, P. A. (1998). Role of the SH3-ligand domain of simian immunodeficiency virus Nef in interaction with Nef-associated kinase and simian AIDS in rhesus macaques. J Virol 72, 5820-5830.
    • (1998) J. Virol. , vol.72 , pp. 5820-5830
    • Khan, I.H.1    Sawai, E.T.2    Antonio, E.3    Weber, C.J.4    Mandell, C.P.5    Montbriand, P.6    Luciw, P.A.7
  • 44
    • 0030836543 scopus 로고    scopus 로고
    • Association of simian immunodeficiency virus Nef with cellular serine/threonine kinases is dispensable for the development of AIDS in rhesus macaques
    • & 7 other authors
    • Lang, S. M., Iafrate, A. J., Stahl-Hennig, C. & 7 other authors (1997). Association of simian immunodeficiency virus Nef with cellular serine/threonine kinases is dispensable for the development of AIDS in rhesus macaques. Nat Med 3, 860-865.
    • (1997) Nat. Med. , vol.3 , pp. 860-865
    • Lang, S.M.1    Iafrate, A.J.2    Stahl-Hennig, C.3
  • 45
    • 0033519616 scopus 로고    scopus 로고
    • Immunologic and virologic status after 14 to 18 years of infection with an attenuated strain of HIV-1
    • & 9 other authors
    • Learmont, J. C., Geczy, A. F., Mills, J. & 9 other authors (1999). Immunologic and virologic status after 14 to 18 years of infection with an attenuated strain of HIV-1. N Engl J Med 340, 1715-1722.
    • (1999) N. Engl. J. Med. , vol.340 , pp. 1715-1722
    • Learmont, J.C.1    Geczy, A.F.2    Mills, J.3
  • 46
    • 0028805516 scopus 로고
    • A single amino acid in the SH3 domain of Hck determines its high affinity and specificity in binding to HIV-1 Nef protein
    • Lee, C.-H., Leung, B., Lemmon, M. A., Zheng, J., Cowburn, D., Kuriyan, J. & Saksela, K. (1995). A single amino acid in the SH3 domain of Hck determines its high affinity and specificity in binding to HIV-1 Nef protein. EMBO J 14, 5006-5015.
    • (1995) EMBO J. , vol.14 , pp. 5006-5015
    • Lee, C.-H.1    Leung, B.2    Lemmon, M.A.3    Zheng, J.4    Cowburn, D.5    Kuriyan, J.6    Saksela, K.7
  • 47
    • 0026758448 scopus 로고
    • A novel Ets-related transcription factor, Elf-1, binds to human immunodeficiency virus type 2 regulatory elements that are required for inducible trans activation in T cells
    • Leiden, J. R., Wang, C.-Y., Petryniak, B., Markovitz, D. M., Nabel, G. J. & Thompson, C. B. (1992). A novel Ets-related transcription factor, Elf-1, binds to human immunodeficiency virus type 2 regulatory elements that are required for inducible trans activation in T cells. J Virol 66, 5890-5897.
    • (1992) J. Virol. , vol.66 , pp. 5890-5897
    • Leiden, J.R.1    Wang, C.-Y.2    Petryniak, B.3    Markovitz, D.M.4    Nabel, G.J.5    Thompson, C.B.6
  • 48
    • 0033577730 scopus 로고    scopus 로고
    • Two elements target SIV Nef to the AP-2 clathrin adaptor complex, but only one is required for the induction of CD4 endocytosis
    • Lock, M., Greenberg, M. E., Iafrate, A. J., Swigut, T., Muench, J., Kirchhoff, F., Shohdy, N. & Skowronski, J. (1999). Two elements target SIV Nef to the AP-2 clathrin adaptor complex, but only one is required for the induction of CD4 endocytosis. EMBO J 18, 2722-2733.
    • (1999) EMBO J. , vol.18 , pp. 2722-2733
    • Lock, M.1    Greenberg, M.E.2    Iafrate, A.J.3    Swigut, T.4    Muench, J.5    Kirchhoff, F.6    Shohdy, N.7    Skowronski, J.8
  • 49
    • 0030775332 scopus 로고    scopus 로고
    • Activation of the T-cell receptor signaling pathway by Nef from an aggressive strain of simian immunodeficiency virus
    • Luo, W. & Peterlin, M. (1997). Activation of the T-cell receptor signaling pathway by Nef from an aggressive strain of simian immunodeficiency virus. J Virol 71, 9531-9537.
    • (1997) J. Virol. , vol.71 , pp. 9531-9537
    • Luo, W.1    Peterlin, M.2
  • 50
    • 0033013962 scopus 로고    scopus 로고
    • Nef-induced CD4 and major histocompatibility complex class I (MHC-I) down-regulation are governed by distinct determinants: N-terminal α helix and proline repeat of Nef selectively regulate MHC-I trafficking
    • Mangasarian, A., Piguet, V., Wang, J.-K., Chen, Y.-L. & Trono, D. (1999). Nef-induced CD4 and major histocompatibility complex class I (MHC-I) down-regulation are governed by distinct determinants: N-terminal α helix and proline repeat of Nef selectively regulate MHC-I trafficking. J Virol 73, 1964-1973.
    • (1999) J. Virol. , vol.73 , pp. 1964-1973
    • Mangasarian, A.1    Piguet, V.2    Wang, J.-K.3    Chen, Y.-L.4    Trono, D.5
  • 51
    • 0032566903 scopus 로고    scopus 로고
    • SH3-domain binding function of HIV-1 Nef is required for association with a PAK-related kinase
    • Manninen, A., Hiipakka, M., Vihinen, M., Lu, W., Mayer, B. J. & Saksela, K. (1998). SH3-domain binding function of HIV-1 Nef is required for association with a PAK-related kinase. Virology 250, 273-282.
    • (1998) Virology , vol.250 , pp. 273-282
    • Manninen, A.1    Hiipakka, M.2    Vihinen, M.3    Lu, W.4    Mayer, B.J.5    Saksela, K.6
  • 52
    • 0026802973 scopus 로고
    • Activation of the human immunodeficiency virus type 2 enhancer is dependent on purine box and κB regulatory elements
    • Markovitz, D., Smith, M., Hilfinger, J., Hannibal, M. C., Petryniak, B. & Nabel, G. J. (1992). Activation of the human immunodeficiency virus type 2 enhancer is dependent on purine box and κB regulatory elements. J Virol 66, 5479-5484.
    • (1992) J. Virol. , vol.66 , pp. 5479-5484
    • Markovitz, D.1    Smith, M.2    Hilfinger, J.3    Hannibal, M.C.4    Petryniak, B.5    Nabel, G.J.6
  • 53
    • 0028102110 scopus 로고
    • Reduced rate of disease development after HIV-2 infection as compared to HIV-1
    • & other authors
    • Marlink, R., Kanki, P., Thior, I. & other authors (1994). Reduced rate of disease development after HIV-2 infection as compared to HIV-1. Science 265, 1587-1590.
    • (1994) Science , vol.265 , pp. 1587-1590
    • Marlink, R.1    Kanki, P.2    Thior, I.3
  • 54
    • 0029019603 scopus 로고
    • Defective accessory genes in a human immunodeficiency virus type-1-infected long-term survivor lacking recoverable virus
    • Michael, N. L., Chang, G., d'Arcy, L., Ehrenberg, P. K., Mariani, R., Busch, M. P., Birx, D. L. & Schwartz, D. H. (1995). Defective accessory genes in a human immunodeficiency virus type-1-infected long-term survivor lacking recoverable virus. J Virol 69, 4228-4236.
    • (1995) J. Virol. , vol.69 , pp. 4228-4236
    • Michael, N.L.1    Chang, G.2    d'Arcy, L.3    Ehrenberg, P.K.4    Mariani, R.5    Busch, M.P.6    Birx, D.L.7    Schwartz, D.H.8
  • 56
    • 0033589665 scopus 로고    scopus 로고
    • Lack of differences in nef alleles among HIV-infected asymptomatic long-term survivors and those who progressed to disease
    • Mourich, D. V., Lee, S., Reyes-Teran, G., Mackewicz, C. E. & Levy, J. A. 1999). Lack of differences in nef alleles among HIV-infected asymptomatic long-term survivors and those who progressed to disease. AIDS Res Hum Retroviruses 15, 1573-1575.
    • (1999) AIDS Res. Hum. Retroviruses , vol.15 , pp. 1573-1575
    • Mourich, D.V.1    Lee, S.2    Reyes-Teran, G.3    Mackewicz, C.E.4    Levy, J.A.5
  • 57
    • 0038421334 scopus 로고    scopus 로고
    • HIV/AIDS infection, situation in Portugal at 30 June 2002, doc. 128
    • National AIDS Commission National Institute of Health, Lisbon, Portugal: CVEDT
    • National AIDS Commission (2002). HIV/AIDS infection, situation in Portugal at 30 June 2002, doc. 128. National Institute of Health, Lisbon, Portugal: CVEDT.
    • (2002)
  • 58
    • 0033541476 scopus 로고    scopus 로고
    • Predominance of human immunodeficiency virus type 2 subtype B in Abidjan, Ivory Coast
    • & 11 other authors
    • Pieniazek, D., Ellenberger, D., Janini, L. M. & 11 other authors (1999). Predominance of human immunodeficiency virus type 2 subtype B in Abidjan, Ivory Coast. AIDS Res Hum Retroviruses 15, 603-608.
    • (1999) AIDS Res. Hum. Retroviruses , vol.15 , pp. 603-608
    • Pieniazek, D.1    Ellenberger, D.2    Janini, L.M.3
  • 59
    • 0032987238 scopus 로고    scopus 로고
    • The Nef protein of primate lentiviruses
    • Piguet, V. & Trono, D. (1999). The Nef protein of primate lentiviruses. Rev Med Virol 9, 111-120.
    • (1999) Rev. Med. Virol. , vol.9 , pp. 111-120
    • Piguet, V.1    Trono, D.2
  • 60
    • 0032079665 scopus 로고    scopus 로고
    • Mechanisms of Nef-induced CD4 endocytosis: Nef connects CD4 with the mu chain of adaptor complexes
    • Piguet, V., Chen, Y.-L., Mangasarian, A., Foti, M., Carpentier, J.-L. & Trono, D. (1998). Mechanisms of Nef-induced CD4 endocytosis: Nef connects CD4 with the mu chain of adaptor complexes. EMBO J 17, 2472-2481.
    • (1998) EMBO J. , vol.17 , pp. 2472-2481
    • Piguet, V.1    Chen, Y.-L.2    Mangasarian, A.3    Foti, M.4    Carpentier, J.-L.5    Trono, D.6
  • 61
    • 0033515427 scopus 로고    scopus 로고
    • Nef-induced CD4 degradation: A diacidic-based motif in Nef functions as a lysosomal targeting signal through the binding of β-COP in endosomes
    • Piguet, V., Gu, F., Foti, M., Demaurex, N., Gruenberg, J., Carpentier, J.-L. & Trono, D. (1999). Nef-induced CD4 degradation: a diacidic-based motif in Nef functions as a lysosomal targeting signal through the binding of β-COP in endosomes. Cell 97, 63-73.
    • (1999) Cell , vol.97 , pp. 63-73
    • Piguet, V.1    Gu, F.2    Foti, M.3    Demaurex, N.4    Gruenberg, J.5    Carpentier, J.-L.6    Trono, D.7
  • 62
    • 0033370597 scopus 로고    scopus 로고
    • Lower human immunodeficiency (HIV) type 2 viral load reflects the difference in pathogenicity of HIV-1 and HIV-2
    • Popper, S. J., Sarr, A. D., Travers, K. U., Gueye-Ndiaye, A., Mboup, S., Essex, M. E. & Kanki, P. J. (1999). Lower human immunodeficiency (HIV) type 2 viral load reflects the difference in pathogenicity of HIV-1 and HIV-2. J Infect Dis 180, 1116-1121.
    • (1999) J. Infect. Dis. , vol.180 , pp. 1116-1121
    • Popper, S.J.1    Sarr, A.D.2    Travers, K.U.3    Gueye-Ndiaye, A.4    Mboup, S.5    Essex, M.E.6    Kanki, P.J.7
  • 64
    • 0036268538 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 2
    • Reeves, J. D. & Doms, R. W. (2002). Human immunodeficiency virus type 2. J Gen Virol 83, 1253-1265.
    • (2002) J. Gen. Virol. , vol.83 , pp. 1253-1265
    • Reeves, J.D.1    Doms, R.W.2
  • 65
    • 0028878783 scopus 로고
    • Proline-rich (PxxP) motifs in HIV-1 Nef bind to SH3 domains of a subset of Src kinases and are required for the enhanced growth of Nef+ viruses but not for down-regulation of CD4
    • Saksela, K., Cheng, G. & Baltimore, D. (1995). Proline-rich (PxxP) motifs in HIV-1 Nef bind to SH3 domains of a subset of Src kinases and are required for the enhanced growth of Nef+ viruses but not for down-regulation of CD4. EMBO J 14, 484-491.
    • (1995) EMBO J. , vol.14 , pp. 484-491
    • Saksela, K.1    Cheng, G.2    Baltimore, D.3
  • 66
    • 0002315910 scopus 로고    scopus 로고
    • Towards a better understanding of the epidemiology of HIV-2
    • Schim van der Loeff, M. F. & Aaby, P. (1999). Towards a better understanding of the epidemiology of HIV-2. AIDS 13 (suppl. A), S69-S84.
    • (1999) AIDS , vol.13 , Issue.SUPPL. A
    • Schim van der Loeff, M.F.1    Aaby, P.2
  • 67
    • 0025093306 scopus 로고
    • Biological and molecular variability of human immunodeficiency virus type 2 isolates from The Gambia
    • Schulz, T. F., Whitby, D., Hoad, J. G., Corrah, T., Whittle, H. & Weiss, R. A. (1990). Biological and molecular variability of human immunodeficiency virus type 2 isolates from The Gambia. J Virol 64, 5177-5182.
    • (1990) J. Virol. , vol.64 , pp. 5177-5182
    • Schulz, T.F.1    Whitby, D.2    Hoad, J.G.3    Corrah, T.4    Whittle, H.5    Weiss, R.A.6
  • 68
    • 0032710838 scopus 로고    scopus 로고
    • Consistence viral evolutionary changes associated with the progression of human immunodeficiency virus type 1 infection
    • & 9 other authors
    • Shankarappa, R., Margolick, J. B., Gange, S. J. & 9 other authors (1999). Consistence viral evolutionary changes associated with the progression of human immunodeficiency virus type 1 infection. J Virol 73, 10489-10502.
    • (1999) J. Virol. , vol.73 , pp. 10489-10502
    • Shankarappa, R.1    Margolick, J.B.2    Gange, S.J.3
  • 69
    • 0034948709 scopus 로고    scopus 로고
    • Nef triggers a transcriptional program in T cells imitating single-signal T cell activation and inducing HIV virulence mediators
    • Simmons, A., Aluvihare, V. & McMichael, A. (2001). Nef triggers a transcriptional program in T cells imitating single-signal T cell activation and inducing HIV virulence mediators. Immunity 14, 763-777.
    • (2001) Immunity , vol.14 , pp. 763-777
    • Simmons, A.1    Aluvihare, V.2    McMichael, A.3
  • 70
    • 0027482122 scopus 로고
    • Cellular and plasma viral load in patients infected with HIV-2
    • & 9 other authors
    • Simon, F., Matheron, S., Tamalet, C. & 9 other authors (1993). Cellular and plasma viral load in patients infected with HIV-2. AIDS 7, 1411-1417.
    • (1993) AIDS , vol.7 , pp. 1411-1417
    • Simon, F.1    Matheron, S.2    Tamalet, C.3
  • 71
    • 16744369116 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 2 (HIV-2) in Portugal: Clinical spectrum, circulating subtypes, virus isolation and plasma viral load
    • & 10 other authors
    • Soriano, V., Gomes, P., Heneine, W. & 10 other authors (2000). Human immunodeficiency virus type 2 (HIV-2) in Portugal: clinical spectrum, circulating subtypes, virus isolation and plasma viral load. J Med Virol 61, 111-116.
    • (2000) J. Med. Virol. , vol.61 , pp. 111-116
    • Soriano, V.1    Gomes, P.2    Heneine, W.3
  • 72
    • 17344373542 scopus 로고    scopus 로고
    • Evidence of Net truncation in human immunodeficiency virus type 2 infection
    • & 7 other authors
    • Switzer, W. M., Wiktor, S., Soriano, V. & 7 other authors (1998). Evidence of Net truncation in human immunodeficiency virus type 2 infection. J Infect Dis 177, 65-71.
    • (1998) J. Infect. Dis. , vol.177 , pp. 65-71
    • Switzer, W.M.1    Wiktor, S.2    Soriano, V.3
  • 73
    • 0027968068 scopus 로고
    • CLUSTAL W: Improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice
    • Thompson, J. D., Higgins, D. G. & Gibson, T. J. (1994). CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res 22, 4673-4680.
    • (1994) Nucleic Acids Res. , vol.22 , pp. 4673-4680
    • Thompson, J.D.1    Higgins, D.G.2    Gibson, T.J.3
  • 74
    • 0029031494 scopus 로고
    • Repair and evolution of nef in vivo modulates simian immunodeficiency virus virulence
    • Whatmore, A. M., Cook, N., Hall, G. A., Sharpe, S., Rud, E. W. & Cranage, M. P. (1995). Repair and evolution of nef in vivo modulates simian immunodeficiency virus virulence. J Virol 69, 5117-5123.
    • (1995) J. Virol. , vol.69 , pp. 5117-5123
    • Whatmore, A.M.1    Cook, N.2    Hall, G.A.3    Sharpe, S.4    Rud, E.W.5    Cranage, M.P.6
  • 77
    • 0035173735 scopus 로고    scopus 로고
    • HIV-1 Nef associated PAK and P13-kinases stimulate Akt-independent Bad-phosphorylation to induce anti-apoptotic signals
    • Wolf, D., Witte, V., Laffert, B., Blume, K., Stromer, E., Trapp, S., d'Aloja, P., Schurmann, A. & Baur, A. S. (2001). HIV-1 Nef associated PAK and P13-kinases stimulate Akt-independent Bad-phosphorylation to induce anti-apoptotic signals. Nat Med 7, 1217-1224.
    • (2001) Nat. Med. , vol.7 , pp. 1217-1224
    • Wolf, D.1    Witte, V.2    Laffert, B.3    Blume, K.4    Stromer, E.5    Trapp, S.6    d'Aloja, P.7    Schurmann, A.8    Baur, A.S.9
  • 78
    • 0034631403 scopus 로고    scopus 로고
    • Identification of a new HIV-2 subtype based on phylogenetic analysis of full-length genomic sequence
    • Yamaguchi, J., Devare, S. G. & Brennan, C. (2000). Identification of a new HIV-2 subtype based on phylogenetic analysis of full-length genomic sequence. AIDS Res Hum Retroviruses 9, 925-930.
    • (2000) AIDS Res. Hum. Retroviruses , vol.9 , pp. 925-930
    • Yamaguchi, J.1    Devare, S.G.2    Brennan, C.3


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