Lower human immunodeficiency virus (HIV) type 2 viral load reflects the difference in pathogenicity of HIV-1 and HIV-2

Journal of Infectious Diseases

Volumn 180, Issue 4, 1999, Pages 1116-1121

  Popper, Stephen J ^a   Sarr, Abdoulaye Dieng ^a   Travers, Karin U ^a   Guèye Ndiaye, Aissatou ^b   Mboup, Souleymane ^b   Essex, Myron E ^a   Kanki, Phyllis J ^a,c  

^a Harvard AIDS Institute   (United States)

^b UNIVERSITÉ CHEIKH ANTA DIOP   (Senegal)

^c HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

VIRUS RNA;

ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 2; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LEUKOCYTE COUNT; NONHUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VIREMIA; VIRUS LOAD; VIRUS PATHOGENESIS;

ADULT; CD4 LYMPHOCYTE COUNT; COHORT STUDIES; FEMALE; HIV INFECTIONS; HIV SEROPOSITIVITY; HIV-1; HIV-2; HUMANS; PROSTITUTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, VIRAL; SENEGAL; TRANSCRIPTION, GENETIC; VIRAL LOAD;

EID: 0033370597     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/315010     Document Type: Article

References (39)

1. Ho DD, Neumann AU, Perelson AS, Chen W, Leonard JM, Markowitz M. Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection. Nature 1995; 373:123-6.
2. Wei XP, Ghosh SK, Taylor ME, et al. Viral dynamics in human immunodeficiency virus type 1 infection. Nature 1995; 373:117-22.
3. Bagnarelli P, Menzo S, Valenza A, et al. Molecular profile of human immunodeficiency virus type 1 infection in symptomless patients and in patients with AIDS. J Virol 1992; 66:7328-35.
4. Piatak M, Jr., Saag MS, Yang LC, et al. High levels of HIV-1 in plasma during all stages of infection determined by competitive. Science 1993; 259:1749-54.
5. Stein DS, Lyles RH, Graham NM, et al. Predicting clinical progression or death in subjects with early-stage human immunodeficiency virus (HIV) infection: a comparative analysis of quantification of HIV RNA, soluble tumor necrosis factor type H receptors, neopterin, and beta2-microglobulin. Multicenter AIDS Cohort Study. J Infect Dis 1997; 176:1161-7.
6. Mellors JW, Kingsley LA, Rinaldo CR, Jr., et al. Quuntitation of HIV-1 RNA in plasma predicts outcome after seroconversion. Ann Intern Med 1995; 122:573-9.
7. Lefrere JJ, Roudotthoraval F, Mariotti M, et al. The risk of disease progression is determined during the first year of human immunodeficiency virus type 1 infection. J Infect Dis 1998; 177:1541-8.
8. Mellors JW, Rinaldo CR, Jr., Gupta P, White RM, Todd M, Kingsley LA. Prognosis in HIV-1 infection predicted by the quantity of virus in plasma. Science 1996; 272:1167-70.
9. + lymphocyte counts and the risk of progression to AIDS. Veterans Affairs Cooperative Study Group on AIDS. New Engl J Mal 1996; 334:426-31.
10. Cao Y, Qin L, Zhang L, Safrit J, Ho DD. Characterization of long-term survivors of human immunodeficiency virus type 1 infection. Immunol Lett 1996; 51:7-13.
11. Pantalco G, Menzo S, Vaccarezza M, et al. Studies in subjects with long-term nonprogressive human immunodeficiency virus infection. New Engl J Med 1995; 332:209-16.
12. Vesanen M, Stevens CE, Taylor PE, Rubinstein P, Saksela K. Stability in controlling viral replication identifies long-term nonprogressors as a distinct subgroup among human immunodeficiency virus type 1 infected persons. J Virol 1996; 70:9035-40.
13. Balotta C, Bagnarelli P, Riva C, et al. Comparable biological and molecular determinants in HIV type: 1-infected long-term nonprogressors and recently infected individuals. AIDS Res Hum Retroviruses 1997; 13:337-41.
14. Watson A, Ranchalis J, Travis B, et al. Plasma viremia in macaques infected with simian immunodeficiency virus: plasma viral load early in infection predicts survival. J Virol 1997; 71:284-90.
15. Hirsch VM, Fuerst TR, Sutter G, et al. Patterns of viral replication correlate with outcome in simian immunodeficiency virus (SIV) infected macaques: effect of prior immunization with a trivalent SIV vaccine in modified vaccinia virus ankara. J Virol 1996; 70:3741-52.
16. Hirsch VM, Dapolito G, Johnson PR, et al. Induction of AIDS by simian immunodeficiency virus from an African green monkey: species-specific variation in pathogenicity correlates with the extent of in vivo replication. J Virol 1995; 69:955-67.
17. Diehl LJ, Mathiason-Dubard CK, Oneil LL, Hoover EA. Plasma viral RNA load predicts disease progression in accelerated feline immunodeficiency virus infection. J Virol 1996; 70:2503-7.
18. Rey-Cuille MA, Berthier JL, Bomsel-Demontoy MC, et al. Simian immunodeficiency virus replicates to high levels in sooty mangabeys without inducing disease. J Virol 1998; 72:3872-86.
19. Beer B, Scherer J, Megede JZ, Norley S, Baier M, Kurth R. Lack of dichotomy between virus load of peripheral blood and lymph nodes during long-term simian immunodeficiency virus infection of African green monkeys. Virology 1996; 219:367-75.
20. Norley SG. SIVagm infection of its natural African green monkey host. Immunology Letters 1996; 51:53-8.
21. Kanki PJ, Travers KU, Mboup S, et al. Slower heterosexual spread of HIV-2 than HIV-1. Lancet 1994; 343:943-6.
22. Adjorlolo-Johnson G, Decock KM, Ekpini E, et al. Prospective comparison of mother-to-child transmission of HIV-l and HIV-2 in Abidjan, Ivory Coast. JAMA 1994; 272:462-6.
23. Andreasson PA, Dias F, Naucler A, Andersson S, Biberfeld G. A prospective study of vertical transmission of HIV-2 in Bissau, Guinea-Bissau. AIDS 1993; 7:989-93.
24. Marlink R, Kanki P, Thior I, et al. Reduced rate of disease development after HIV-2 infection as compared to HIV-1. Science 1994; 265:1587-90.
25. Traore I, Marlink R, Thior I, et al. HIV-2 as a model for long-term non-progression. In: XI International Conference on AIDS. Vancouver. BC: 1996.
26. Simon F, Matheron S, Tamalet C, et al. Cellular and plasma viral load in patients infected with HIV-2. AIDS 1993; 7:1411-7.
27. Berry N, Ariyoshi K, Jobe O, et al. HIV type 2 proviral load measured by quantitative polymerase chain reaction correlates with CD4 lymphopenia in HIV type 2-infected individuals. AIDS Res Hum Retroviruses 1994; 10:1031-7.
28. Sarr AD, Popper S, Thior I, et al. Relationship between HIV-2 proviral load and CD4 lymphocyte count differs in HIV monotypic and dual infections. J Hum Virol 1999; 2:45-51.
29. Kanki P, M'Boup S, Marlink R, et al. Prevalence and risk determinants of human immunodeficiency virus type 2 (HIV-2) and human immunodeficiency virus type 1 (HIV-1) in west African female prostitutes. Am J Epidemiol 1992; 136:895-907.
30. Shibata R, Miura T, Hayami M, et al. Mutational analysis of the human immunodeficiency virus type 2 (HIV-2) genome in relation to HIV-1 and simian immunodeficiency virus SIV (AGM). J Virol 1990; 64:742-7.
31. Grankvist O, Bredberg-Raden U, Gustafsson A, et al. Improved detection of HIV-2 DNA in clinical samples using a nested primer-based polymerase chain reaction. J Acquir Immune Defic Syndr 1992; 5:286-93.
32. Collins ML, Zayati C, Detmer JJ, et al. Preparation and characterisation of RNA standards for use in quantitative branched DNA hybridization assays. Anal Biochem 1995; 226:120-9.
33. + lymphocyte counts. AIDS 1998; 12:131-7.
34. Kanki PJ, Hamel DJ, Sankale JL, et al. Human immunodeficiency virus type 11 subtypes differ in disease progression. J Infect Dis 1999; 179:68-73.
35. Coste J, Montes B, Reynes J, et al. Comparative evaluation of three assays for the quantitation of human immunodeficiency virus type 1 RNA in plasma. J Med Virol 1996; 50:293-302.
36. + T-cell T-cell count and function: markers with reciprocal predictive value over time after seroconversion. AIDS 1997; 11:1799-1806.
37. O'Brien TR, Rosenberg PS, Yellin F, Goedert JJ. Longitudinal HIV-1 RNA levels in a cohort of homosexual men. J Acquir Immune Defic Syndr Retrovirol 1998; 18:155-61.
38. + lymphocytes as prognostic markers of HIV-1 infection. Ann Intern Med 1997; 126:946-54.
39. Berry N, Ariyoshi K, Jaffar S, et al. Low peripheral blood viral HIV-2 RNA in individuals with high CD4 percentage differentiates HIV-2 from HIV1 infection. J Hum Virol 1998; 1:457-68.