Species differences in acrylonitrile metabolism and toxicity between experimental animals and humans based on observations in human accidental poisonings

Archives of Toxicology

Volumn 74, Issue 4-5, 2000, Pages 184-189

  Thier, Ricarda ^a   Lewalter, Jürgen ^b   Bolt, Hermann M ^a  

^a LEIBNIZ RESEARCH CENTRE FOR WORKING ENVIRONMENT AND HUMAN FACTORS   (Germany)

^b BAYER AG   (Germany)

Author keywords

Acrylonitrile; Antidote therapy; Cyanide; Intoxication; N Cyanoethyl asparaginic acid; N Cyanoethyl valine; Protein adducts

Indexed keywords

ACETYLCYSTEINE; ACRYLONITRILE; CYANIDE; EPOXIDE; INDUSTRIAL CHEMICAL; SODIUM THIOSULFATE;

ADULT; BIOLOGICAL MONITORING; CLINICAL ARTICLE; CLINICAL FEATURE; CYANIDE POISONING; DETOXIFICATION; GENOTOXICITY; GLUTATHIONE METABOLISM; HUMAN; INHALATION; INTOXICATION; MALE; NONHUMAN; OCCUPATIONAL EXPOSURE; OCCUPATIONAL HAZARD; PRIORITY JOURNAL; REVIEW; SKIN; SPECIES DIFFERENCE;

ACRYLONITRILE; ADULT; ANIMALS; CARCINOGENS; HUMANS; MALE; MIDDLE AGED; OCCUPATIONAL EXPOSURE; SPECIES SPECIFICITY;

EID: 0033763824     PISSN: 03405761     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002040000109     Document Type: Review

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