메뉴 건너뛰기




Volumn 30, Issue 3, 2000, Pages 253-285

Renal toxicity and carcinogenicity of trichloroethylene: Key results, mechanisms, and controversies

Author keywords

GST polymorphisms; Nephrotoxicity; Renal carcinogenicity; Trichloroethylene; VHL gene

Indexed keywords

GLUTATHIONE TRANSFERASE; TRICHLOROETHYLENE;

EID: 1642633556     PISSN: 10408444     EISSN: None     Source Type: Journal    
DOI: 10.1080/10408440091159202     Document Type: Review
Times cited : (99)

References (130)
  • 1
    • 0013372491 scopus 로고
    • Trichloroethylene
    • International Agency for Research on Cancer, Ed. Lyon: IARC, IARC Monographs on the evaluation of carcinogenic risks to humans
    • IARC, Trichloroethylene. In: International Agency for Research on Cancer, Ed. Dry Cleaning, Some Chlorinated Solvents and Other Industrial Chemicals. Lyon: IARC, 1995, 75-158. (IARC Monographs on the evaluation of carcinogenic risks to humans, Vol. 63).
    • (1995) Dry Cleaning, Some Chlorinated Solvents and Other Industrial Chemicals , vol.63 , pp. 75-158
  • 3
    • 0030714940 scopus 로고    scopus 로고
    • Dose-dependent binding of trichloroethylene to hepatic DNA and protein at low doses in mice
    • Kautiainen, A., Vogel, J. S., and Turteltaub, K. W., Dose-dependent binding of trichloroethylene to hepatic DNA and protein at low doses in mice, Chem. Biol. Interact., 1997; 106: 109-121.
    • (1997) Chem. Biol. Interact. , vol.106 , pp. 109-121
    • Kautiainen, A.1    Vogel, J.S.2    Turteltaub, K.W.3
  • 4
    • 0032559676 scopus 로고    scopus 로고
    • Increased frequency of micronucleated kidney cells in rats exposed to halogenated anesthetics
    • Robbiano, L., Mereto, E., Morando, A. M., Pastore, P., and Brambilla, G., Increased frequency of micronucleated kidney cells in rats exposed to halogenated anesthetics, Mutat. Res., 1998; 413: 1-6.
    • (1998) Mutat. Res. , vol.413 , pp. 1-6
    • Robbiano, L.1    Mereto, E.2    Morando, A.M.3    Pastore, P.4    Brambilla, G.5
  • 5
    • 0028696513 scopus 로고
    • Structures of DNA adducts formed from haloketenes and halothioketenes: A study to identify possible adducts formed from trichloro- and perchloroethene through bioactivation by glutathione conjugation
    • Müller, M., Birner, G., Henschler, D., and Dekant, W., Structures of DNA adducts formed from haloketenes and halothioketenes: A study to identify possible adducts formed from trichloro-and perchloroethene through bioactivation by glutathione conjugation, IARC Sci. Publ., 1994; 115: 423-428.
    • (1994) IARC Sci. Publ. , vol.115 , pp. 423-428
    • Müller, M.1    Birner, G.2    Henschler, D.3    Dekant, W.4
  • 6
    • 0039991859 scopus 로고    scopus 로고
    • Reactivity of haloketenes and halothioketenes with nucleobases: Chemical characterization of reaction products
    • Müller, M., Birner, G., and Dekant, W., Reactivity of haloketenes and halothioketenes with nucleobases: chemical characterization of reaction products, Chem. Res. Toxicol., 1998; 11: 454-463.
    • (1998) Chem. Res. Toxicol. , vol.11 , pp. 454-463
    • Müller, M.1    Birner, G.2    Dekant, W.3
  • 7
    • 0031670446 scopus 로고    scopus 로고
    • Chlorothioketene, the ultimate reactive intermediate formed by cysteine conjugate beta-lyase-mediated cleavage of the trichloroethylene metabolite S-(1,2-dichlorovinyl)-L-cysteine, forms cytosine adducts in organic solvents, but not in aqueous solution
    • Völkel, W. and Dekant, W., Chlorothioketene, the ultimate reactive intermediate formed by cysteine conjugate beta-lyase-mediated cleavage of the trichloroethylene metabolite S-(1,2-dichlorovinyl)-L-cysteine, forms cytosine adducts in organic solvents, but not in aqueous solution, Chem. Res. Toxicol., 1998; 11: 1082-1088.
    • (1998) Chem. Res. Toxicol. , vol.11 , pp. 1082-1088
    • Völkel, W.1    Dekant, W.2
  • 8
    • 0028842980 scopus 로고
    • Metabolism and kinetics of trichloroethylene in relation to carcinogenicity. Relevance of the mercapturic acid pathway
    • Goeptar, A. R., Commandeur, J. N. M., van Ommen, B., van Bladeren, P. J., and Vermeulen, N. P. E., Metabolism and kinetics of trichloroethylene in relation to carcinogenicity. Relevance of the mercapturic acid pathway, Chem. Res. Toxicol., 1995; 8: 3-21.
    • (1995) Chem. Res. Toxicol. , vol.8 , pp. 3-21
    • Goeptar, A.R.1    Commandeur, J.N.M.2    Van Ommen, B.3    Van Bladeren, P.J.4    Vermeulen, N.P.E.5
  • 9
    • 0013814496 scopus 로고
    • Metabolism of trichloroethylene in liver microsomes. II. Identification of the reaction product as chloral hydrate
    • Byington, K. H, and Leibman, K. C., Metabolism of trichloroethylene in liver microsomes. II. Identification of the reaction product as chloral hydrate, Mol. Pharmacol., 1965; 1: 247-254.
    • (1965) Mol. Pharmacol. , vol.1 , pp. 247-254
    • Byington, K.H.1    Leibman, K.C.2
  • 10
    • 0013814166 scopus 로고
    • Metabolism of trichloroethylene in liver microsomes. I. Characteristics of the reaction
    • Leibman, K. C., Metabolism of trichloroethylene in liver microsomes. I. Characteristics of the reaction, Mol. Pharmacol., 1965; 1: 239-246.
    • (1965) Mol. Pharmacol. , vol.1 , pp. 239-246
    • Leibman, K.C.1
  • 11
    • 0022503191 scopus 로고
    • Identification of S-1,2-dichlorovinyl-N-acetyl-cysteine as a urinary metabolite of trichloroethylene: A possible explanation for its nephrocarcinogenicity in male rats
    • Dekant, W., Metzler, M., and Henschler, D., Identification of S-1,2-dichlorovinyl-N-acetyl-cysteine as a urinary metabolite of trichloroethylene: a possible explanation for its nephrocarcinogenicity in male rats, Biochem. Pharmacol., 1986; 35: 2455-2458.
    • (1986) Biochem. Pharmacol. , vol.35 , pp. 2455-2458
    • Dekant, W.1    Metzler, M.2    Henschler, D.3
  • 12
    • 0025119798 scopus 로고
    • Identification of N-acetyl(2,2-dichlorovinyl)- and N-acetyl( 1,2-dichlorovinyl)-L-cysteine as two regioisomeric mercapturic acids of trichloroethylene in the rat
    • Commandeur, J. N., and Vermeulen, N. P., Identification of N-acetyl(2,2-dichlorovinyl)-and N-acetyl( 1,2-dichlorovinyl)-L-cysteine as two regioisomeric mercapturic acids of trichloroethylene in the rat, Chem. Res. Toxicol., 1990; 3: 212-218.
    • (1990) Chem. Res. Toxicol. , vol.3 , pp. 212-218
    • Commandeur, J.N.1    Vermeulen, N.P.2
  • 13
    • 0025129134 scopus 로고
    • Metabolism of trichloroethylene - In vivo and in vitro evidence for activation by glutathione conjugation
    • Dekant, W., Koob, M., and Henschler, D., Metabolism of trichloroethylene - in vivo and in vitro evidence for activation by glutathione conjugation, Chem. Biol. Interact., 1990; 73: 89-101.
    • (1990) Chem. Biol. Interact. , vol.73 , pp. 89-101
    • Dekant, W.1    Koob, M.2    Henschler, D.3
  • 14
    • 0026504543 scopus 로고
    • A comparative study on the contribution of cytochrome P-450 isozymes to metabolism of benzene, toluene and trichloroethylene in rat liver
    • Nakajima, T., Wang, R. S., Elovaara, E., Park, S. S., Gelboin, H. V., and Vainio, H., A comparative study on the contribution of cytochrome P-450 isozymes to metabolism of benzene, toluene and trichloroethylene in rat liver, Biochem. Pharmacol., 1992; 43: 251-257.
    • (1992) Biochem. Pharmacol. , vol.43 , pp. 251-257
    • Nakajima, T.1    Wang, R.S.2    Elovaara, E.3    Park, S.S.4    Gelboin, H.V.5    Vainio, H.6
  • 15
    • 2642709830 scopus 로고    scopus 로고
    • Use of kinetic and mechanistic data in species extrapolation of bioactivation: Cytochrome P-450 dependent trichloroethylene metabolism at occupationally relevant concentrations
    • Lipscomb, J. C., Garrett, C. M., and Snawder, J. E., Use of kinetic and mechanistic data in species extrapolation of bioactivation: Cytochrome P-450 dependent trichloroethylene metabolism at occupationally relevant concentrations, J. Occup. Health, 1998; 40: 110-117.
    • (1998) J. Occup. Health , vol.40 , pp. 110-117
    • Lipscomb, J.C.1    Garrett, C.M.2    Snawder, J.E.3
  • 16
    • 0020473257 scopus 로고
    • Oxidation of trichloroethylene by liver microsomal cytochrome P-450: Evidence for chlorine migration in a transition state not involving trichloroethylene oxide
    • Miller, R. E. and Guengerich, F. P., Oxidation of trichloroethylene by liver microsomal cytochrome P-450: evidence for chlorine migration in a transition state not involving trichloroethylene oxide, Biochemistry, 1982; 21: 1090-1097.
    • (1982) Biochemistry , vol.21 , pp. 1090-1097
    • Miller, R.E.1    Guengerich, F.P.2
  • 17
    • 0019415669 scopus 로고
    • Biologische Arbeitsstoff-Toleranzwerte: BAT-Wert für Trichloräthylen
    • Bolt, H. M., Biologische Arbeitsstoff-Toleranzwerte: BAT-Wert für Trichloräthylen, Arbeitsmed. Sozialmed. Präventivmed., 1981; 16: 116-121.
    • (1981) Arbeitsmed. Sozialmed. Präventivmed. , vol.16 , pp. 116-121
    • Bolt, H.M.1
  • 18
    • 0015444399 scopus 로고
    • Trichloroethylene exposure and trichloroethylene metabolites in urine and blood
    • Müller, G., Spassovski, M., and Henschler, D., Trichloroethylene exposure and trichloroethylene metabolites in urine and blood, Arch. Toxicol., 1972; 29: 335-340.
    • (1972) Arch. Toxicol. , vol.29 , pp. 335-340
    • Müller, G.1    Spassovski, M.2    Henschler, D.3
  • 19
    • 0022842223 scopus 로고
    • Metabolic conversion of tri- and tetrachloroethylene: Formation and deactivation of genotoxic intermediates
    • Chambers, P. L., Gehring, P., and Sakai, F., Eds. Tokyo. New York: Elsevier
    • Dekant, W., Metabolic conversion of tri-and tetrachloroethylene: formation and deactivation of genotoxic intermediates. In: Chambers, P. L., Gehring, P., and Sakai, F., Eds. New Concepts and Developments in Toxicology. Proceedings of the 4th International Congress in Toxicology, Tokyo. New York: Elsevier, 1986, 211-221.
    • (1986) New Concepts and Developments in Toxicology. Proceedings of the 4th International Congress in Toxicology , pp. 211-221
    • Dekant, W.1
  • 20
    • 0000666578 scopus 로고
    • Thioketene formation from haloalkenyl 2-nitrophenyl disulfides: Models for biological reactive intermediates of cytotoxic S-conjugates
    • Dekant, W., Urban, G., Görsman, C., and Anders, M. W., Thioketene formation from haloalkenyl 2-nitrophenyl disulfides: models for biological reactive intermediates of cytotoxic S-conjugates, J. Am. Chem. Soc., 1991; 113: 5120-5122.
    • (1991) J. Am. Chem. Soc. , vol.113 , pp. 5120-5122
    • Dekant, W.1    Urban, G.2    Görsman, C.3    Anders, M.W.4
  • 21
    • 0026079136 scopus 로고
    • Bioactivation of xenobiotics by formation of toxic glutathione conjugates
    • Koob, M. and Dekant, W., Bioactivation of xenobiotics by formation of toxic glutathione conjugates, Chem. Biol. Interact., 1991; 77: 107-136.
    • (1991) Chem. Biol. Interact. , vol.77 , pp. 107-136
    • Koob, M.1    Dekant, W.2
  • 22
    • 0342626039 scopus 로고
    • Bioactivation of halogenated xenobiotics by S-conjugate formation
    • Anders, M. W., Dekant, W., Henschler, D., Oberleithner, H., and Silbernagl, S., Eds. San Diego, CA: Academic Press
    • Dekant, W., Anders, M. W., and Monks, J., Bioactivation of halogenated xenobiotics by S-conjugate formation. In: Anders, M. W., Dekant, W., Henschler, D., Oberleithner, H., and Silbernagl, S., Eds. Renal Disposition and Nephrotoxicity of Xenobiotics. San Diego, CA: Academic Press, 1993, 187-215.
    • (1993) Renal Disposition and Nephrotoxicity of Xenobiotics , pp. 187-215
    • Dekant, W.1    Anders, M.W.2    Monks, J.3
  • 23
    • 0027267051 scopus 로고
    • Nephrotoxic and genotoxic N-acetyl-S-dichlorovinyl-L-cysteine is a urinary metabolite after occupational 1,1,2-trichloroethylene exposure in humans: Implications for the risk of trichloroethylene exposure
    • Birner, G., Vamvakas, S., Dekant, W., and Henschler, D., Nephrotoxic and genotoxic N-acetyl-S-dichlorovinyl-L-cysteine is a urinary metabolite after occupational 1,1,2-trichloroethylene exposure in humans: implications for the risk of trichloroethylene exposure, Environ. Health Perspect., 1993; 99: 281-284.
    • (1993) Environ. Health Perspect. , vol.99 , pp. 281-284
    • Birner, G.1    Vamvakas, S.2    Dekant, W.3    Henschler, D.4
  • 24
    • 0029912279 scopus 로고    scopus 로고
    • Biotransformation of trichloroethylene: Dose-dependent excretion of 2,2,2-trichloro-metabolites and mercapturic acids in rats and humans after inhalation
    • Bernauer, U., Birner, G., Dekant, W., and Henschler, D., Biotransformation of trichloroethylene: dose-dependent excretion of 2,2,2-trichloro-metabolites and mercapturic acids in rats and humans after inhalation, Arch. Toxicol., 1996; 70: 338-346.
    • (1996) Arch. Toxicol. , vol.70 , pp. 338-346
    • Bernauer, U.1    Birner, G.2    Dekant, W.3    Henschler, D.4
  • 25
    • 0030800178 scopus 로고    scopus 로고
    • The role of glutathione conjugation in the development of kidney tumors in rats exposed to trichloroethylene
    • Green, T., Dow, J., Ellis, M. K., Foster, J. R., and Odum, J., The role of glutathione conjugation in the development of kidney tumors in rats exposed to trichloroethylene, Chem. Biol. Interact., 1997; 105: 99-117.
    • (1997) Chem. Biol. Interact. , vol.105 , pp. 99-117
    • Green, T.1    Dow, J.2    Ellis, M.K.3    Foster, J.R.4    Odum, J.5
  • 26
    • 0030755987 scopus 로고    scopus 로고
    • Influence of polymorphisms of GSTM1 and GSTT1 for risk renal cell cancer in workers with a long-term and high occupational exposure to trichloroethylene
    • Brüning, T., Lammert, M., Kempkes, M., Thier, R., Golka, K., and Bolt, H. M., Influence of polymorphisms of GSTM1 and GSTT1 for risk renal cell cancer in workers with a long-term and high occupational exposure to trichloroethylene, Arch. Toxicol. 1997; 71: 596-599.
    • (1997) Arch. Toxicol. , vol.71 , pp. 596-599
    • Brüning, T.1    Lammert, M.2    Kempkes, M.3    Thier, R.4    Golka, K.5    Bolt, H.M.6
  • 27
    • 0030662508 scopus 로고    scopus 로고
    • Trichloroethylene induced in cancer in animals and its relevance to humans
    • Green, T., Trichloroethylene induced in cancer in animals and its relevance to humans, J. Occup. Health, 1997; 39: 261-273.
    • (1997) J. Occup. Health , vol.39 , pp. 261-273
    • Green, T.1
  • 28
    • 85033504675 scopus 로고    scopus 로고
    • Trichloroethylene induced mouse lung tumors: Studies of the mode of action and comparisons between species
    • Green, T., Mainwaring, G. W., and Foster, J. R., Trichloroethylene induced mouse lung tumors: studies of the mode of action and comparisons between species, Fund. Appl. Toxicol., 1997; 37: 125-130.
    • (1997) Fund. Appl. Toxicol. , vol.37 , pp. 125-130
    • Green, T.1    Mainwaring, G.W.2    Foster, J.R.3
  • 29
    • 0029148521 scopus 로고
    • S-(1,2-Dichlorovinyl)-L-cysteine-induced nephrotoxicity in the New Zealand white rabbit: Characterization of proteinuria and examination of the potential role of oxidative injury
    • Davis, J. W., Blakeman, D. P., Jolly, R. A., Packwood, W. P., Kolaja, G. J., and Petry, T. W., S-(1,2-Dichlorovinyl)-L-cysteine-induced nephrotoxicity in the New Zealand white rabbit: characterization of proteinuria and examination of the potential role of oxidative injury, Toxicol. Pathol., 1995; 23: 487-497.
    • (1995) Toxicol. Pathol. , vol.23 , pp. 487-497
    • Davis, J.W.1    Blakeman, D.P.2    Jolly, R.A.3    Packwood, W.P.4    Kolaja, G.J.5    Petry, T.W.6
  • 30
    • 0030775018 scopus 로고    scopus 로고
    • A role for c-myc in chemically induced cell death
    • Zhan, Y., Cleveland, J. L., and Stevens, J. L., A role for c-myc in chemically induced cell death, Mol. Cell. Biol., 1997; 17: 6755-6764.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 6755-6764
    • Zhan, Y.1    Cleveland, J.L.2    Stevens, J.L.3
  • 31
    • 0031919247 scopus 로고    scopus 로고
    • Glutathione conjugation of trichloroethylene in rats and mice: Sex-species-, and tissue-dependent differences
    • Lash, L. H., Qian, W., Putt, D. A., Jacobs, K., Elfarra, A. A., Krause, R. J., and Parker, J. C., Glutathione conjugation of trichloroethylene in rats and mice: sex-species-, and tissue-dependent differences, Drug Metab. Dispos., 1998; 26: 12-19.
    • (1998) Drug Metab. Dispos. , vol.26 , pp. 12-19
    • Lash, L.H.1    Qian, W.2    Putt, D.A.3    Jacobs, K.4    Elfarra, A.A.5    Krause, R.J.6    Parker, J.C.7
  • 32
    • 0031919809 scopus 로고    scopus 로고
    • Acute intoxication with trichloroethylene: Clinical symptoms, toxicokinetics, metabolism and development of biochemical parameters for renal damage
    • Brüning, T., Vamvakas, S., Makropoulos, V., and Birner, G., Acute intoxication with trichloroethylene: clinical symptoms, toxicokinetics, metabolism and development of biochemical parameters for renal damage, Toxicol. Sci., 1998; 41: 157-165.
    • (1998) Toxicol. Sci. , vol.41 , pp. 157-165
    • Brüning, T.1    Vamvakas, S.2    Makropoulos, V.3    Birner, G.4
  • 33
    • 0033534408 scopus 로고    scopus 로고
    • Identification of S-(1,2-dichlorovinyl)glutathione in the blood of human volunteers exposed to trichloroethylene
    • Lash, L. H., Putt, D. A., Brashear, W. T., Abbas, R., Parker, J. C., and Fisher, J. W., Identification of S-(1,2-dichlorovinyl)glutathione in the blood of human volunteers exposed to trichloroethylene, J. Toxicol. Environ. Health, 1999; 56A: 1-21.
    • (1999) J. Toxicol. Environ. Health , vol.56 A , pp. 1-21
    • Lash, L.H.1    Putt, D.A.2    Brashear, W.T.3    Abbas, R.4    Parker, J.C.5    Fisher, J.W.6
  • 34
    • 0032982150 scopus 로고    scopus 로고
    • Gender differences in risk of renal cell carcinoma and occupational exposures to chlorinated aliphatic hydrocarbons
    • Dosemeci, M., Cocco, P., and Chow, W. H., Gender differences in risk of renal cell carcinoma and occupational exposures to chlorinated aliphatic hydrocarbons, Am. J. Ind. Med., 1999; 36: 54-59.
    • (1999) Am. J. Ind. Med. , vol.36 , pp. 54-59
    • Dosemeci, M.1    Cocco, P.2    Chow, W.H.3
  • 35
    • 85037956638 scopus 로고    scopus 로고
    • Formic acid excretion in rats dosed with trichloroethylene: A possible explanation for long term kidney damage
    • abstr. no. 1385
    • Wilmer, J. W., Green, T., Dow, J., Foster, J. R., and Hext, P. M., Formic acid excretion in rats dosed with trichloroethylene: a possible explanation for long term kidney damage, Toxicol. Sci., 1998; 42: 288 (abstr. no. 1385).
    • (1998) Toxicol. Sci. , vol.42 , pp. 288
    • Wilmer, J.W.1    Green, T.2    Dow, J.3    Foster, J.R.4    Hext, P.M.5
  • 36
    • 0032524925 scopus 로고    scopus 로고
    • Formic acid excretion in rats exposed to trichloroethylene: A possible explanation for renal toxicity in long-term studies
    • Green, T., Dow, J., Foster, J. R., and Hext, P. M., Formic acid excretion in rats exposed to trichloroethylene: a possible explanation for renal toxicity in long-term studies, Toxicology, 1998; 127: 39-47.
    • (1998) Toxicology , vol.127 , pp. 39-47
    • Green, T.1    Dow, J.2    Foster, J.R.3    Hext, P.M.4
  • 37
    • 0018876656 scopus 로고
    • Characteristics of haloethylene-induced acetonemia in rats
    • Filser, J. G. and Bolt, H. M., Characteristics of haloethylene-induced acetonemia in rats. Arch. Toxicol., 1980; 45: 109-116.
    • (1980) Arch. Toxicol. , vol.45 , pp. 109-116
    • Filser, J.G.1    Bolt, H.M.2
  • 39
    • 0021889753 scopus 로고
    • Covalent interaction of reactive metabolites with cytosolic coenzyme A as mechanism of haloethylene-induced acetonemia
    • Simon, P., Bolt, H. M., Filser, J. G., and Bolt, H. M., Covalent interaction of reactive metabolites with cytosolic coenzyme A as mechanism of haloethylene-induced acetonemia, Biochem. Pharmacol., 1985; 34: 1981-1986.
    • (1985) Biochem. Pharmacol. , vol.34 , pp. 1981-1986
    • Simon, P.1    Bolt, H.M.2    Filser, J.G.3    Bolt, H.M.4
  • 40
    • 0019417030 scopus 로고
    • Inhalation pharmacokinetics based on gas uptake studies. II. Pharmacokinetics of acetone in rats
    • Hallier, E., Filser, J. G., and Bolt, H. M., Inhalation pharmacokinetics based on gas uptake studies. II. Pharmacokinetics of acetone in rats, Arch. Toxicol., 1981; 47: 293-304.
    • (1981) Arch. Toxicol. , vol.47 , pp. 293-304
    • Hallier, E.1    Filser, J.G.2    Bolt, H.M.3
  • 41
    • 0031955703 scopus 로고    scopus 로고
    • Effect of hexachloro-1,3-butadiene on renal carcinogenesis in male rats pretreated with N-ethyl-N-hydroxyethyl-nitrosamine
    • Nakagawa, Y., Kitahori, Y., Cho, M., Konishi, N., Tsumatani, K. C., Ozono, S., Okajima, E., Hirao, Y., and Hiasa, Y., Effect of hexachloro-1,3-butadiene on renal carcinogenesis in male rats pretreated with N-ethyl-N-hydroxyethyl-nitrosamine, Toxicol. Pathol., 1998; 26: 361-366.
    • (1998) Toxicol. Pathol. , vol.26 , pp. 361-366
    • Nakagawa, Y.1    Kitahori, Y.2    Cho, M.3    Konishi, N.4    Tsumatani, K.C.5    Ozono, S.6    Okajima, E.7    Hirao, Y.8    Hiasa, Y.9
  • 42
    • 0030052417 scopus 로고    scopus 로고
    • Cancer in relation to occupational exposure to trichloroethylene
    • Weiss, N. L., Cancer in relation to occupational exposure to trichloroethylene, Occup. Environ. Med., 1996; 53: 1-5.
    • (1996) Occup. Environ. Med. , vol.53 , pp. 1-5
    • Weiss, N.L.1
  • 44
    • 0028344623 scopus 로고
    • Updated and expanded Swedish cohort study on trichloroethylene and cancer risk
    • Axelson, O., Seldén, A., Andersson, K., and Hogstedt, C., Updated and expanded Swedish cohort study on trichloroethylene and cancer risk, J. Occup. Med., 1994; 36: 556-562.
    • (1994) J. Occup. Med. , vol.36 , pp. 556-562
    • Axelson, O.1    Seldén, A.2    Andersson, K.3    Hogstedt, C.4
  • 47
    • 0031806607 scopus 로고    scopus 로고
    • Mortality of aerospace exposed to trichloroethylene
    • Morgan, R., Kelsh, M., Zhao, K., and Heringer S., Mortality of aerospace exposed to trichloroethylene, Epidemiology, 1998; 9: 424-431.
    • (1998) Epidemiology , vol.9 , pp. 424-431
    • Morgan, R.1    Kelsh, M.2    Zhao, K.3    Heringer, S.4
  • 49
    • 0028929211 scopus 로고
    • Increased incidence of renal cell tumors in a cohort of cardbord workers exposed to trichloroethylene
    • Henschler, D., Vamvakas, S., Lammert, M., Dekant, W., Kraus, B., Thomas, B., and Ulm, K., Increased incidence of renal cell tumors in a cohort of cardbord workers exposed to trichloroethylene, Arch. Toxicol., 1995; 69: 291-299.
    • (1995) Arch. Toxicol. , vol.69 , pp. 291-299
    • Henschler, D.1    Vamvakas, S.2    Lammert, M.3    Dekant, W.4    Kraus, B.5    Thomas, B.6    Ulm, K.7
  • 50
    • 0030757807 scopus 로고    scopus 로고
    • Assessment of health effects of trichloroethylene
    • Kaneko, T., Wang, P. Y., and Sato, A., Assessment of health effects of trichloroethylene, Ind. Health, 1997; 35: 301-324.
    • (1997) Ind. Health , vol.35 , pp. 301-324
    • Kaneko, T.1    Wang, P.Y.2    Sato, A.3
  • 51
    • 0030768274 scopus 로고    scopus 로고
    • A critical review of epidemiology studies of trichloroethylene and perchloroethylene and risk of renal-cell cancer
    • McLaughlin, J. K. and Blot, W. J., A critical review of epidemiology studies of trichloroethylene and perchloroethylene and risk of renal-cell cancer, Int. Arch. Occup. Environ. Health, 1997; 70: 222-231.
    • (1997) Int. Arch. Occup. Environ. Health , vol.70 , pp. 222-231
    • McLaughlin, J.K.1    Blot, W.J.2
  • 54
    • 0031920256 scopus 로고    scopus 로고
    • Mortality and cancer incidence of aircraft maintenance workers exposed to trichloroethylene and other organic solvents and chemicals: An extended follow up
    • Blair, A., Hartge, P., Stewart, P.A., McAdams, M., and Lubin, J., Mortality and cancer incidence of aircraft maintenance workers exposed to trichloroethylene and other organic solvents and chemicals: an extended follow up, Occup. Environ. Med., 1998; 55: 161-171.
    • (1998) Occup. Environ. Med. , vol.55 , pp. 161-171
    • Blair, A.1    Hartge, P.2    Stewart, P.A.3    McAdams, M.4    Lubin, J.5
  • 55
    • 0004378291 scopus 로고    scopus 로고
    • (Abschlußbericht), (Schriftenreihe der Bundesanstalt für Arbeitsschutz, Forschung Fb 780), Bremerhaven: Wissenschaftsverlag
    • Greiser, E. and Molzahn, M., Multizentrische Nierenund Urothel-Carcinom-Studie (Abschlußbericht), (Schriftenreihe der Bundesanstalt für Arbeitsschutz, Forschung Fb 780), Bremerhaven: Wissenschaftsverlag, 1997.
    • (1997) Multizentrische Nierenund Urothel-Carcinom-Studie
    • Greiser, E.1    Molzahn, M.2
  • 56
    • 85037953041 scopus 로고    scopus 로고
    • Occupational risk factors for urothelial carcinoma: Agent-specific results from a case-control study in Germany
    • in press
    • Pesch, B., Haerting, J., Klimpel, A., Oelschlägel, B., Ranft, U., and Schill, W., Occupational risk factors for urothelial carcinoma: agent-specific results from a case-control study in Germany, Int. J. Epidemiol., 1999; in press.
    • (1999) Int. J. Epidemiol.
    • Pesch, B.1    Haerting, J.2    Klimpel, A.3    Oelschlägel, B.4    Ranft, U.5    Schill, W.6
  • 58
    • 0029682040 scopus 로고    scopus 로고
    • Preexistence of chronic tubular damage in cases of renal cell cancer after long and high exposure to trichloroethylene
    • Brüning, T., Golka, K., Makropoulos, V., and Bolt, H. M., Preexistence of chronic tubular damage in cases of renal cell cancer after long and high exposure to trichloroethylene, Arch. Toxicol., 1996; 70: 259-260.
    • (1996) Arch. Toxicol. , vol.70 , pp. 259-260
    • Brüning, T.1    Golka, K.2    Makropoulos, V.3    Bolt, H.M.4
  • 59
    • 0031023145 scopus 로고    scopus 로고
    • Characterization of proteinuria in primary glomerulonephritides. SDS-PAGE patterns: Clinical significance and prognostic value of low-molecular-weight ("tubular") proteins
    • Bazzi, C., Petrini, C., Rizza, V., Arrigo, G., Beltrame, A., and D'Amico, G., Characterization of proteinuria in primary glomerulonephritides. SDS-PAGE patterns: clinical significance and prognostic value of low-molecular-weight ("tubular") proteins. Am. J. Kidney Dis., 1997; 29: 27-35.
    • (1997) Am. J. Kidney Dis. , vol.29 , pp. 27-35
    • Bazzi, C.1    Petrini, C.2    Rizza, V.3    Arrigo, G.4    Beltrame, A.5    D'Amico, G.6
  • 60
    • 18744437410 scopus 로고    scopus 로고
    • Pathological excretion patterns of urinary proteins in renal cell cancer patients exposed to trichloroethylene
    • Brüning, T., Mann, H., Melzer, H., Sundberg, A. G. M., and Bolt, H. M., Pathological excretion patterns of urinary proteins in renal cell cancer patients exposed to trichloroethylene, Occup. Med., 1999; 49: 1-7.
    • (1999) Occup. Med. , vol.49 , pp. 1-7
    • Brüning, T.1    Mann, H.2    Melzer, H.3    Sundberg, A.G.M.4    Bolt, H.M.5
  • 61
    • 0142204618 scopus 로고    scopus 로고
    • Subclinical changes in urinary protein excretion of renal cell cancer patients: Effect of high occupational exposure to trichloroethylene
    • Golka, K., Hartert-Raulf, T., Schöps, W., Kierfeld, G., Brüning, T., and Bolt, H. M., Subclinical changes in urinary protein excretion of renal cell cancer patients: Effect of high occupational exposure to trichloroethylene, Centr. Eur. J. Occup. Environ. Med., 1997; 3: 167-174.
    • (1997) Centr. Eur. J. Occup. Environ. Med. , vol.3 , pp. 167-174
    • Golka, K.1    Hartert-Raulf, T.2    Schöps, W.3    Kierfeld, G.4    Brüning, T.5    Bolt, H.M.6
  • 63
    • 1642637678 scopus 로고    scopus 로고
    • Increased activation of dihaloalkanes in rat liver by upregulation of class theta glutathione-S-transferase T1
    • abstract no. 1350
    • Sherratt, P. J., Manson, M. M., Green, T., and Hayes, J. D., Increased activation of dihaloalkanes in rat liver by upregulation of class theta glutathione-S-transferase T1, Toxicol. Sci., 1998; 42: 1-S, 275 (abstract no. 1350).
    • (1998) Toxicol. Sci. , vol.42
    • Sherratt, P.J.1    Manson, M.M.2    Green, T.3    Hayes, J.D.4
  • 64
    • 0031602552 scopus 로고    scopus 로고
    • Comparison of GST theta activity in liver and kidney of four species
    • Thier, R., Wiebel, F. A., Schulz, T. G., Kinkel, A., Brüning, T., and Bolt, H. M., Comparison of GST theta activity in liver and kidney of four species, Arch. Toxicol., 1997; Suppl. 20: 471-474.
    • (1997) Arch. Toxicol. , Issue.20 SUPPL. , pp. 471-474
    • Thier, R.1    Wiebel, F.A.2    Schulz, T.G.3    Kinkel, A.4    Brüning, T.5    Bolt, H.M.6
  • 69
    • 0030900929 scopus 로고    scopus 로고
    • Renal cell carcinoma in trichloroethylene (TRI)-exposed persons are associated with somatic mutations in the von Hippel-Lindau (VHL) tumor suppressor gene
    • Brüning, T., Weirich, G., Hornauer, M. A., Höfler, H., and Brauch, H., Renal cell carcinoma in trichloroethylene (TRI)-exposed persons are associated with somatic mutations in the von Hippel-Lindau (VHL) tumor suppressor gene, Arch. Toxicol., 1997; 71: 332-335.
    • (1997) Arch. Toxicol. , vol.71 , pp. 332-335
    • Brüning, T.1    Weirich, G.2    Hornauer, M.A.3    Höfler, H.4    Brauch, H.5
  • 70
    • 0033583793 scopus 로고    scopus 로고
    • Trichloroethylene exposure and specific somatic mutations in patients with renal cell carcinoma
    • Brauch, H., Weirich, G., Hornauer, M.A., Störkel, S., Wöhl, T., and Brüning, T., Trichloroethylene exposure and specific somatic mutations in patients with renal cell carcinoma, J. Natl. Cancer Inst., 1999; 91: 854-861.
    • (1999) J. Natl. Cancer Inst. , vol.91 , pp. 854-861
    • Brauch, H.1    Weirich, G.2    Hornauer, M.A.3    Störkel, S.4    Wöhl, T.5    Brüning, T.6
  • 74
    • 0029944971 scopus 로고    scopus 로고
    • Mutation of the VHL gene is associated exclusively with the development of non-papillary renal cell carcinomas
    • Kenck, C., Wilhelm, M., Bugert, P., Staehler, G., and Kovacs, G., Mutation of the VHL gene is associated exclusively with the development of non-papillary renal cell carcinomas, J. Pathol. 1996; 179: 157-161.
    • (1996) J. Pathol. , vol.179 , pp. 157-161
    • Kenck, C.1    Wilhelm, M.2    Bugert, P.3    Staehler, G.4    Kovacs, G.5
  • 76
    • 0017651350 scopus 로고
    • Carcinogenicity of trichloroethylene: Fact or artifact?
    • Henschler, D., Eder, E., Neudecker, T., and Metzler, M., Carcinogenicity of trichloroethylene: fact or artifact?, Arch. Toxicol., 1977; 37: 233-236.
    • (1977) Arch. Toxicol. , vol.37 , pp. 233-236
    • Henschler, D.1    Eder, E.2    Neudecker, T.3    Metzler, M.4
  • 77
    • 0017621612 scopus 로고
    • Carcinogenicity studies on halogenated hydrocarbons
    • Weisburger, E. K., Carcinogenicity studies on halogenated hydrocarbons, Environ. Health Perspect., 1977; 21: 7-16.
    • (1977) Environ. Health Perspect. , vol.21 , pp. 7-16
    • Weisburger, E.K.1
  • 79
    • 0033051828 scopus 로고    scopus 로고
    • The von Hippel-Lindau tumor protein: New perspectives
    • Ohh, M. and Kaelin W. G., Jr., The von Hippel-Lindau tumor protein: new perspectives, Mol. Med. Today, 1999; 5: 257-263.
    • (1999) Mol. Med. Today , vol.5 , pp. 257-263
    • Ohh, M.1    Kaelin Jr., W.G.2
  • 80
    • 0033574737 scopus 로고    scopus 로고
    • Structure of the VHL-ElonginC-ElonginB Complex: Implications for VHL Tumor Suppressor Function
    • Stebbins, C .E., Kaelin, W. G., Jr., and Pavletich, N. P., Structure of the VHL-ElonginC-ElonginB Complex: Implications for VHL Tumor Suppressor Function, Science, 1999; 284: 455-461.
    • (1999) Science , vol.284 , pp. 455-461
    • Stebbins, C.E.1    Kaelin Jr., W.G.2    Pavletich, N.P.3
  • 81
    • 0030592517 scopus 로고    scopus 로고
    • Lessons from hereditary colorectal cancer
    • Kinzler, K. W. and Vogelstein, B., Lessons from hereditary colorectal cancer, Cell, 1996; 87: 159-170.
    • (1996) Cell , vol.87 , pp. 159-170
    • Kinzler, K.W.1    Vogelstein, B.2
  • 83
  • 85
    • 0015043748 scopus 로고
    • Mutation and cancer: Statistical study of retinoblastoma
    • Knudson, A., Mutation and cancer: statistical study of retinoblastoma, Proc. Natl. Acad. Sci. U.S.A., 1971; 68: 820-823.
    • (1971) Proc. Natl. Acad. Sci. U.S.A. , vol.68 , pp. 820-823
    • Knudson, A.1
  • 87
    • 0032979092 scopus 로고    scopus 로고
    • Novel somatic mutations in the VHL gene in Swedish archived sporadic renal cell carcinoma
    • Yang, K., Lindblad, P., Egevad, L., and Hemminki, K., Novel somatic mutations in the VHL gene in Swedish archived sporadic renal cell carcinoma, Cancer Lett., 1999; 141: 1-8.
    • (1999) Cancer Lett. , vol.141 , pp. 1-8
    • Yang, K.1    Lindblad, P.2    Egevad, L.3    Hemminki, K.4
  • 88
    • 0023023223 scopus 로고
    • Bacterial beta-lyase mediated cleavage and mutagenicity of cysteine conjugates derived from the nephrocarcinogenic alkenes trichloroethylene, tetrachloroethylene and hexachlorobutadiene
    • Dekant, W., Vamvakas, S., Berthold, K., Schmidt, S., Wild, D., and Henschler, D., Bacterial beta-lyase mediated cleavage and mutagenicity of cysteine conjugates derived from the nephrocarcinogenic alkenes trichloroethylene, tetrachloroethylene and hexachlorobutadiene, Chem. Biol. Interact., 1986; 15: 31-45.
    • (1986) Chem. Biol. Interact. , vol.15 , pp. 31-45
    • Dekant, W.1    Vamvakas, S.2    Berthold, K.3    Schmidt, S.4    Wild, D.5    Henschler, D.6
  • 89
    • 0023225398 scopus 로고
    • Enzymatic transformation of mercapturic acids derived from halogenated alkenes to reactive and mutagenic intermediates
    • Vamvakas, S., Dekant, W., Berthold, K., Schmidt, S., Wild, D., and Henschler, D., Enzymatic transformation of mercapturic acids derived from halogenated alkenes to reactive and mutagenic intermediates, Biochem. Pharmacol., 1987; 36: 2741-2748.
    • (1987) Biochem. Pharmacol. , vol.36 , pp. 2741-2748
    • Vamvakas, S.1    Dekant, W.2    Berthold, K.3    Schmidt, S.4    Wild, D.5    Henschler, D.6
  • 90
    • 0025734238 scopus 로고
    • Mutagenicity and cytotoxicity of two regioisomeric mercapturic acids and cysteine S-conjugates of trichloroethylene
    • Commandeur, J. N. M., Boogaard, J., Mulder, G. J., and Vermeulen, N. P. E., Mutagenicity and cytotoxicity of two regioisomeric mercapturic acids and cysteine S-conjugates of trichloroethylene, Arch. Toxicol., 1991; 65: 373-380.
    • (1991) Arch. Toxicol. , vol.65 , pp. 373-380
    • Commandeur, J.N.M.1    Boogaard, J.2    Mulder, G.J.3    Vermeulen, N.P.E.4
  • 91
    • 0032583897 scopus 로고    scopus 로고
    • S-(1,2-dichlorovinyl)-L cysteine-induced dedifferentiation and p53 gene mutations in LLC-PK1 cell: A comparative investigations with S-(2-chloroethyl)cysteine, potassium bromate, cisplatinum and styrene oxide
    • Richter, H. and Vamvakas, S., S-(1,2-dichlorovinyl)-L cysteine-induced dedifferentiation and p53 gene mutations in LLC-PK1 cell: a comparative investigations with S-(2-chloroethyl)cysteine, potassium bromate, cisplatinum and styrene oxide, Toxicol. Lett., 1998; 94: 145-157.
    • (1998) Toxicol. Lett. , vol.94 , pp. 145-157
    • Richter, H.1    Vamvakas, S.2
  • 92
    • 0024604605 scopus 로고
    • Bioactivation of nephrotoxic haloalkenes by glutathione conjugation: Formation of toxic and mutagenic intermediates by cysteine conjugate ß-lyase
    • Dekant, W., Vamvakas, S., and Anders, M. W., Bioactivation of nephrotoxic haloalkenes by glutathione conjugation: formation of toxic and mutagenic intermediates by cysteine conjugate ß-lyase, Drug Metab. Rev., 1989; 20: 43-83.
    • (1989) Drug Metab. Rev. , vol.20 , pp. 43-83
    • Dekant, W.1    Vamvakas, S.2    Anders, M.W.3
  • 93
    • 0032545016 scopus 로고    scopus 로고
    • Von Hippel-Lindau gene mutations in N-nitrosodimethylamine-induced rat renal epithelial tumors
    • Shiao, Y-H., Rice, J. M., Anderson, L. M., Diwan, B. A., and Hard, G. C., Von Hippel-Lindau gene mutations in N-nitrosodimethylamine-induced rat renal epithelial tumors, J. Natl. Cancer Inst,. 1998; 22: 1720-1723.
    • (1998) J. Natl. Cancer Inst,. , vol.22 , pp. 1720-1723
    • Shiao, Y.-H.1    Rice, J.M.2    Anderson, L.M.3    Diwan, B.A.4    Hard, G.C.5
  • 94
    • 0031468634 scopus 로고    scopus 로고
    • Combining physiologically based pharmacokinetic modelling with Monte Carlo simulation to derive an acute inhalation guidance value for trichloroethylene
    • Simon, T. W., Combining physiologically based pharmacokinetic modelling with Monte Carlo simulation to derive an acute inhalation guidance value for trichloroethylene, Regul. Toxicol. Pharmacol., 1997; 26: 257-270.
    • (1997) Regul. Toxicol. Pharmacol. , vol.26 , pp. 257-270
    • Simon, T.W.1
  • 96
    • 0025903543 scopus 로고
    • An association between mutagenicity of the Ara test of Salmonella typhimurium and carcinogenicity in rodent for 16 halogenated aliphatic hydrocarbons
    • Roldán-Arjona, T., Garciá-Pedrajas, M. D., Luque-Romero, F. L., Hera, C., and Pueyo, C., An association between mutagenicity of the Ara test of Salmonella typhimurium and carcinogenicity in rodent for 16 halogenated aliphatic hydrocarbons, Mutagenesis, 1991; 6: 199-205.
    • (1991) Mutagenesis , vol.6 , pp. 199-205
    • Roldán-Arjona, T.1    Garciá-Pedrajas, M.D.2    Luque-Romero, F.L.3    Hera, C.4    Pueyo, C.5
  • 97
    • 0001296211 scopus 로고
    • Mutagenic activity of chemicals identified in drinking water
    • Scott, D., Bridges, B. A., and Soberls, F. H., Eds. Amsterdam: Elsevier/ North-Holland
    • Simmon, V. F., Kauhanen, K., and Tardiff, R. G., Mutagenic activity of chemicals identified in drinking water: In: Scott, D., Bridges, B. A., and Soberls, F. H., Eds. Progress in Toxicology, Amsterdam: Elsevier/ North-Holland, 1977; 249-258.
    • (1977) Progress in Toxicology , pp. 249-258
    • Simmon, V.F.1    Kauhanen, K.2    Tardiff, R.G.3
  • 98
    • 0018622371 scopus 로고
    • Mutagenicity of inhalation anaesthetics: Trichloroethylene, divinyl ether, nitrous oxide and cyclopropana
    • Baden, J. M., Kelley, M., Mazze, R. I., and Simmon, V. F., Mutagenicity of inhalation anaesthetics: trichloroethylene, divinyl ether, nitrous oxide and cyclopropana, Br. J. Anaesthesiol., 1979; 51: 417-421.
    • (1979) Br. J. Anaesthesiol. , vol.51 , pp. 417-421
    • Baden, J.M.1    Kelley, M.2    Mazze, R.I.3    Simmon, V.F.4
  • 99
    • 0018345978 scopus 로고
    • Mutagenic and alkylating metabolites of halo-ethylenes, chlorobutadienes and dichlorobutenes produced by rodent or human liver tissues
    • Bartsch, H., Malaveille, C., Barbin, A., and Planche, G., Mutagenic and alkylating metabolites of halo-ethylenes, chlorobutadienes and dichlorobutenes produced by rodent or human liver tissues, Arch. Toxicol., 1979; 41: 249-277.
    • (1979) Arch. Toxicol. , vol.41 , pp. 249-277
    • Bartsch, H.1    Malaveille, C.2    Barbin, A.3    Planche, G.4
  • 100
    • 0020263329 scopus 로고
    • Mutagenicity of trichlororethylene in Salmonella typhimurium TA100
    • Crebelli, R., Bignami, M., Conti, L., and Carere, A., Mutagenicity of trichlororethylene in Salmonella typhimurium TA100, Ann. Ist. Super. Sanitá, 1982; 18: 117-122.
    • (1982) Ann. Ist. Super. Sanitá , vol.18 , pp. 117-122
    • Crebelli, R.1    Bignami, M.2    Conti, L.3    Carere, A.4
  • 101
    • 0021879775 scopus 로고
    • Activities of chlorinated ethane and ethylene compounds in the Salmonella/rat microsome mutagenesis and rat hepatocyte/DNA repair assays under vapor phase exposure conditions
    • Shimada, T., Swanson, A. F., Leber, P., and Williams, G. M., Activities of chlorinated ethane and ethylene compounds in the Salmonella/rat microsome mutagenesis and rat hepatocyte/DNA repair assays under vapor phase exposure conditions, Cell. Biol. Toxicol., 1985; 1: 159-179.
    • (1985) Cell. Biol. Toxicol. , vol.1 , pp. 159-179
    • Shimada, T.1    Swanson, A.F.2    Leber, P.3    Williams, G.M.4
  • 102
    • 0022458177 scopus 로고
    • Salmonella mutagenicity tests II. Results from the testing of 270 chemicals
    • Mortelmans, K., Haworth, S., Lawlor, T., Speck, W., Tainer, B., and Zeiger, E., Salmonella mutagenicity tests II. Results from the testing of 270 chemicals, Environ. Mutagen., 1986; 8: (Suppl. 7), 1-119.
    • (1986) Environ. Mutagen. , vol.8 , Issue.7 SUPPL. , pp. 1-119
    • Mortelmans, K.1    Haworth, S.2    Lawlor, T.3    Speck, W.4    Tainer, B.5    Zeiger, E.6
  • 103
    • 0024437577 scopus 로고
    • Conditions affecting the mutagenicity of trichloroethylene in Salmonella
    • McGregor, D. B., Reynolds, D. M., and Zeiger, E., Conditions affecting the mutagenicity of trichloroethylene in Salmonella, Environ. Mol. Mutagen., 1989; 13: 197-202.
    • (1989) Environ. Mol. Mutagen. , vol.13 , pp. 197-202
    • McGregor, D.B.1    Reynolds, D.M.2    Zeiger, E.3
  • 104
    • 0019571678 scopus 로고
    • Identification and mutagenic properties of some chlorinated aliphatic compounds in the spent liquor from kraft pulp chlorination
    • Kringstad, K. P., Ljungquist, P. O., de Sousa, F., and Strömberg, L. M., Identification and mutagenic properties of some chlorinated aliphatic compounds in the spent liquor from kraft pulp chlorination, Environ. Sci. Technol., 1981; 15: 562-566.
    • (1981) Environ. Sci. Technol. , vol.15 , pp. 562-566
    • Kringstad, K.P.1    Ljungquist, P.O.2    De Sousa, F.3    Strömberg, L.M.4
  • 106
    • 0021967948 scopus 로고
    • Mutagenicity of trichloroethylene, trichloroethanal and chloral hydrate in Aspergillus nidulans
    • Crebelli, R., Conti, G., Conti, L., and Carere A., Mutagenicity of trichloroethylene, trichloroethanal and chloral hydrate in Aspergillus nidulans, Mutat. Res., 1985; 155: 105-111.
    • (1985) Mutat. Res. , vol.155 , pp. 105-111
    • Crebelli, R.1    Conti, G.2    Conti, L.3    Carere, A.4
  • 107
    • 0020664031 scopus 로고
    • In vivo and in vitro mutagenicity studies of a possible carcinogen, trichloroethylene and its two stabilizers, epichlorohydrin and 1,2-epoxybutane
    • Rossi, A. M., Migliore, L., Barale, R., and Loprieno, N., In vivo and in vitro mutagenicity studies of a possible carcinogen, trichloroethylene and its two stabilizers, epichlorohydrin and 1,2-epoxybutane, Teratog. Carcinog. Mutagen., 1983; 3: 75-87.
    • (1983) Teratog. Carcinog. Mutagen. , vol.3 , pp. 75-87
    • Rossi, A.M.1    Migliore, L.2    Barale, R.3    Loprieno, N.4
  • 108
    • 0023883618 scopus 로고
    • The mutagenic activity of selected compounds at the TK locus: Rodent vs. human cells
    • Caspary, W. J., Langenbach, R., Penman, B. W., Crespi, C., Myhr, B. C., and Michell, A. D., The mutagenic activity of selected compounds at the TK locus: rodent vs. human cells, Mutat. Res. 1988; 196: 61-81.
    • (1988) Mutat. Res. , vol.196 , pp. 61-81
    • Caspary, W.J.1    Langenbach, R.2    Penman, B.W.3    Crespi, C.4    Myhr, B.C.5    Michell, A.D.6
  • 110
    • 0018185153 scopus 로고
    • Transforming activities of trichlororethylene and proposed industrial alternatives
    • Price, P. J., Hassett, C. M., and Mansfield, J. L. Transforming activities of trichlororethylene and proposed industrial alternatives, In Vitro, 1978; 14: 290-293.
    • (1978) In Vitro , vol.14 , pp. 290-293
    • Price, P.J.1    Hassett, C.M.2    Mansfield, J.L.3
  • 111
    • 0020002153 scopus 로고
    • 2 and interaction of a metabolic with liver DNA in rats and mice
    • 2 and interaction of a metabolic with liver DNA in rats and mice, J. Toxicol. Environ. Health, 1982; 9: 797-813.
    • (1982) J. Toxicol. Environ. Health , vol.9 , pp. 797-813
    • Parchman, L.G.1    Magee, P.N.2
  • 112
    • 0022538708 scopus 로고
    • Induction of single-strand breaks in DNA of mice by trichloroethylene and tetrachloroethylene
    • Walles, S. A. S., Induction of single-strand breaks in DNA of mice by trichloroethylene and tetrachloroethylene, Toxicol. Lett. 1986; 31: 31-35.
    • (1986) Toxicol. Lett. , vol.31 , pp. 31-35
    • Walles, S.A.S.1
  • 113
    • 0023887960 scopus 로고
    • Induction of strand breaks in DNA by trichloroethylene and metabolites in rat and mouse liver in vivo
    • Nelson, M. A. and Bull, R. J., Induction of strand breaks in DNA by trichloroethylene and metabolites in rat and mouse liver in vivo, Toxicol., Appl. Pharmacol., 1988; 94: 45-54.
    • (1988) Toxicol., Appl. Pharmacol. , vol.94 , pp. 45-54
    • Nelson, M.A.1    Bull, R.J.2
  • 114
    • 0017659752 scopus 로고
    • The mammalian spot test (Fallfleckentest) with mice
    • Fahrig, R., The mammalian spot test (Fallfleckentest) with mice, Arch. Toxicol. 1977; 38: 87-98.
    • (1977) Arch. Toxicol. , vol.38 , pp. 87-98
    • Fahrig, R.1
  • 115
    • 0023233965 scopus 로고
    • The in vivo - In vitro hepatocyte assay for assessing DNA repair and DNA replication: Studies in the CD-1 mouse
    • Doolittle, D. J., Müller, G., and Scribner, H. E., The in vivo - in vitro hepatocyte assay for assessing DNA repair and DNA replication: studies in the CD-1 mouse. Food Chem. Toxicol., 1987; 25: 399-405.
    • (1987) Food Chem. Toxicol. , vol.25 , pp. 399-405
    • Doolittle, D.J.1    Müller, G.2    Scribner, H.E.3
  • 116
    • 0018881140 scopus 로고
    • Cytogenectic effect of trichloroethylene in the mouse as evaluated by the micronucleus test
    • Duprat, P. and Gradinski, D., Cytogenectic effect of trichloroethylene in the mouse as evaluated by the micronucleus test. IRCS Med. Sci., 1980; 8: 182.
    • (1980) IRCS Med. Sci. , vol.8 , pp. 182
    • Duprat, P.1    Gradinski, D.2
  • 117
    • 0023876298 scopus 로고
    • Mortality of aircraft manufacturing workers in Southern California
    • Garabrant, D. H., Held, J., Langholz, B., and Bernstein, L., Mortality of aircraft manufacturing workers in Southern California, Am. J. Ind. Med., 1988; 13: 683-693.
    • (1988) Am. J. Ind. Med. , vol.13 , pp. 683-693
    • Garabrant, D.H.1    Held, J.2    Langholz, B.3    Bernstein, L.4
  • 118
    • 0027526525 scopus 로고
    • Evaluation of a three-exposure mouse bone marrow micronucleus protocol. Results with 49 chemicals
    • Shelby, M. D., Erexson, G. L., Hook, G. J., and Tice, R. R., Evaluation of a three-exposure mouse bone marrow micronucleus protocol. Results with 49 chemicals, Environ. Mol. Mutagen., 1993; 21: 160-179.
    • (1993) Environ. Mol. Mutagen. , vol.21 , pp. 160-179
    • Shelby, M.D.1    Erexson, G.L.2    Hook, G.J.3    Tice, R.R.4
  • 119
    • 0028179641 scopus 로고
    • Spermatid micronucleus analyses of trichloroethylene and chloral hydrate effects in mice
    • Allen, J. W., Collins, B. W., and Evansky, P. A., Spermatid micronucleus analyses of trichloroethylene and chloral hydrate effects in mice, Mutat. Res., 1994; 323: 81-88.
    • (1994) Mutat. Res. , vol.323 , pp. 81-88
    • Allen, J.W.1    Collins, B.W.2    Evansky, P.A.3
  • 121
    • 0018823054 scopus 로고
    • Trichloroethylene vapours do not produce dominant lethal mutations in male mice
    • Slacik-Erben, R., Roll, R., Franke, G., and Uehleke, H., Trichloroethylene vapours do not produce dominant lethal mutations in male mice, Arch.Toxicol., 1980; 45: 37-44.
    • (1980) Arch.Toxicol. , vol.45 , pp. 37-44
    • Slacik-Erben, R.1    Roll, R.2    Franke, G.3    Uehleke, H.4
  • 122
    • 0018840773 scopus 로고
    • Carcinogenicity study of trichloroethylene by long-term inhalation in three animal species
    • Henschler, D., Romen, W., Elsässer H. M., Reichert, D., Eder, E., and Radwan, Z., Carcinogenicity study of trichloroethylene by long-term inhalation in three animal species, Arch. Toxicol., 1980; 43: 237-248.
    • (1980) Arch. Toxicol. , vol.43 , pp. 237-248
    • Henschler, D.1    Romen, W.2    Elsässer, H.M.3    Reichert, D.4    Eder, E.5    Radwan, Z.6
  • 123
    • 0021067936 scopus 로고
    • Inhalation carcinogenicity of trichloroethylene in mice and rats
    • Fukuda, K., Takemoto, K., and Tsurata, H., Inhalation carcinogenicity of trichloroethylene in mice and rats, Ind. Health, 1983; 21: 243-254.
    • (1983) Ind. Health , vol.21 , pp. 243-254
    • Fukuda, K.1    Takemoto, K.2    Tsurata, H.3
  • 124
    • 0023690866 scopus 로고
    • Long-term carcinogenicity bioassays on trichloroethylene administered by inhalation to Sprague-Dawley rats and Swiss and B6C3F1 mice
    • Maltoni, C., Lefemine, G., Cotti G., and Perino, G., Long-term carcinogenicity bioassays on trichloroethylene administered by inhalation to Sprague-Dawley rats and Swiss and B6C3F1 mice, Ann. N.Y. Acad. Sci., 1988; 534: 316-342.
    • (1988) Ann. N.Y. Acad. Sci. , vol.534 , pp. 316-342
    • Maltoni, C.1    Lefemine, G.2    Cotti, G.3    Perino, G.4
  • 125
    • 0013395630 scopus 로고
    • Bioassay of trichloroethylene for possible carcinogenicity
    • Bethesda, MD: US Dept. of Health, Education, and Welfare
    • NCI, National Cancer Institute, Bioassay of trichloroethylene for possible carcinogenicity. NCI Technical Report, No. 2. Bethesda, MD: US Dept. of Health, Education, and Welfare, 1976.
    • (1976) NCI Technical Report, No. 2
  • 126
    • 0021141224 scopus 로고
    • Carcinogenicity study of trichloroethylene, with and without epoxide stabilizers, in mice
    • Henschler, D., Elsässer, H., Romen, W., and Eder, E., Carcinogenicity study of trichloroethylene, with and without epoxide stabilizers, in mice, J. Cancer Res. Clin. Oncol., 1984; 107: 149-156.
    • (1984) J. Cancer Res. Clin. Oncol. , vol.107 , pp. 149-156
    • Henschler, D.1    Elsässer, H.2    Romen, W.3    Eder, E.4
  • 130
    • 0024917714 scopus 로고
    • Examination of mutagenicity of organic microcontaminations of the environment. IV. Communication
    • Mersh-Sundermann, V., Miller, G., and Hofmeister, A., Examination of mutagenicity of organic microcontaminations of the environment. IV. Communication. Zbl. Hyg., 1989; 189: 266-271.
    • (1989) Zbl. Hyg. , vol.189 , pp. 266-271
    • Mersh-Sundermann, V.1    Miller, G.2    Hofmeister, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.