Smads 2 and 3 are differentially activated by transforming growth factor-β (TGF-β) in quiescent and activated hepatic stellate cells: Constitutive nuclear localization of Smads in activated cells is TGF-β-independent

Journal of Biological Chemistry

Volumn 278, Issue 13, 2003, Pages 11721-11728

  Liu, Chenghai ^a,b   Gaça, Marianna D A ^a   Swenson, E Scott ^a   Vellucci, Vincent F ^a   Reiss, Michael ^a,c   Wells, Rebecca G ^a,d  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b SHANGHAI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^c ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

^d UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODIES; CELLS; PROTEINS;

HEPATIC STELLATE CELLS (HSC);

BIOCHEMISTRY;

ACTIVIN; CYTOKINE ANTIBODY; LEPTOMYCIN B; LINK PROTEIN; PHOSPHOTRANSFERASE INHIBITOR; SMAD ANCHOR FOR RECEPTOR ACTIVATION PROTEIN; SMAD2 PROTEIN; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; DNA BINDING PROTEIN; MADH2 PROTEIN, RAT; MADH3 PROTEIN, RAT; PRIMER DNA; TRANSACTIVATOR PROTEIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL ACTIVATION; CELL DIFFERENTIATION; CELL NUCLEUS; CELL TYPE; CONTROLLED STUDY; CYTOPLASM; EXTRACELLULAR MATRIX; FIBROGENESIS; IN VITRO STUDY; LIVER; LIVER FIBROSIS; MYOFIBROBLAST; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN FAMILY; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION; STELLATE CELL; ANIMAL; CYTOLOGY; METABOLISM; PHOSPHORYLATION; SPRAGUE DAWLEY RAT;

ANIMALIA;

ANIMALS; BASE SEQUENCE; CELL NUCLEUS; DNA PRIMERS; DNA-BINDING PROTEINS; LIVER; PHOSPHORYLATION; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; SMAD2 PROTEIN; SMAD3 PROTEIN; TRANS-ACTIVATORS; TRANSFORMING GROWTH FACTOR BETA;

EID: 0037837754     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M207728200     Document Type: Article

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