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Volumn 1, Issue 3, 2002, Pages 317-340

Exoerythrocytic malaria vaccine development: Understanding host-parasite immunobiology underscores strategic success

Author keywords

Antigen; Immunity; Liver stage; Malaria; Plasmodium; Sporozoite; Vaccine

Indexed keywords

CIRCUMSPOROZOITE PROTEIN 2 VACCINE; CIRCUMSPROZOITE PROTEIN VACCINE; EPITOPE; GLUCOSE REGULATED PROTEIN 70 VACCINE; GLUTAMATE RICH PROTEIN VACCINE; HEAT SHOCK PROTEIN 70 VACCINE; LIVER STAGE ANTIGEN 1 VACCINE; LIVER STAGE ANTIGEN 2 VACCINE; LIVER STAGE ANTIGEN 3 VACCINE; MALARIA VACCINE; MEROZOITE SURFACE PROTEIN 1 VACCINE; PARASITE ANTIGEN; PLASMODIUM FALCIPARUM EXPORTED PROTEIN 1 VACCINE; PLASMODIUM YOELII HEPATIC AND ERYTHROCYTIC STAGE PROTEIN VACCINE; SPOROZOITE AND LIVER STAGE ANTIGEN; SPOROZOITE THREONINE AND ASPARAGINE RICH PROTEIN VACCINE; THROMBOSPONDIN RELATED ADHESION PROTEIN; TOMATINE; UNCLASSIFIED DRUG;

EID: 0037654956     PISSN: 14760584     EISSN: None     Source Type: Journal    
DOI: 10.1586/14760584.1.3.317     Document Type: Review
Times cited : (4)

References (179)
  • 1
    • 0002507116 scopus 로고
    • Clinical features of malaria
    • Gilles HM, Warrell DA (Eds), Edward Arnold, London, UK
    • Warrell DA. Clinical features of malaria. In: Bruce-Chwatt's Essential Malariology, 3rd edn. Gilles HM, Warrell DA (Eds), Edward Arnold, London, UK, 35-49 (1993).
    • (1993) Bruce-Chwatt's Essential Malariology, 3rd Edn. , pp. 35-49
    • Warrell, D.A.1
  • 2
    • 0033629523 scopus 로고    scopus 로고
    • Vaccination against malaria: Targets, strategies and potentiation of immunity to blood stage parasites
    • Taylor-Robinson AW. Vaccination against malaria: targets, strategies and potentiation of immunity to blood stage parasites. Front. Biosci. 5, 16-29 (2000).
    • (2000) Front. Biosci. , vol.5 , pp. 16-29
    • Taylor-Robinson, A.W.1
  • 4
    • 0037034009 scopus 로고    scopus 로고
    • Medical need, scientific opportunity and the drive for antimalarial drugs
    • Ridley RG. Medical need, scientific opportunity and the drive for antimalarial drugs. Nature 415, 686-693 (2002). Excellent consideration of the need for novel antimalarial strategies and the public-private partnerships that need to be forged in order to build on scientific opportunities.
    • (2002) Nature , vol.415 , pp. 686-693
    • Ridley, R.G.1
  • 5
    • 0031941178 scopus 로고    scopus 로고
    • Immunoregulation of malarial infection: Balancing the vices and virtues
    • Taylor-Robinson AW. Immunoregulation of malarial infection: balancing the vices and virtues. Int. J. Parasitol. 28, 135-148 (1998).
    • (1998) Int. J. Parasitol. , vol.28 , pp. 135-148
    • Taylor-Robinson, A.W.1
  • 6
    • 0032742301 scopus 로고    scopus 로고
    • A role for cytokines in potentiation of malaria vaccines through immunological modulation of blood stage infection
    • Taylor-Robinson AW, Smith EC. A role for cytokines in potentiation of malaria vaccines through immunological modulation of blood stage infection. Immunol. Rev. 171, 105-123 (1999).
    • (1999) Immunol. Rev. , vol.171 , pp. 105-123
    • Taylor-Robinson, A.W.1    Smith, E.C.2
  • 7
    • 0003136886 scopus 로고
    • Immunology of human malaria
    • Gilles HM, Warrell DA (Eds), Edward Arnold, London, UK
    • Marsh K. Immunology of human malaria. In: Bruce-Chwatt's Essential Malarioloy, 3rd edn. Gilles HM, Warrell DA (Eds), Edward Arnold, London, UK, 60-77 (1993).
    • (1993) Bruce-Chwatt's Essential Malarioloy, 3rd Edn. , pp. 60-77
    • Marsh, K.1
  • 8
    • 0031960217 scopus 로고    scopus 로고
    • Research towards vaccines against malaria
    • Miller L, Hoffman S. Research towards vaccines against malaria. Nature Med. 4, 520-524 (1998).
    • (1998) Nature Med. , vol.4 , pp. 520-524
    • Miller, L.1    Hoffman, S.2
  • 9
    • 0027207375 scopus 로고
    • Bidirectional cytokine interactions in the maternal-fetal relationship: Is successful pregnancy a Th2 phenomenon?
    • Wegmann TG, Lin H, Guilbert L, Mosmann TR. Bidirectional cytokine interactions in the maternal-fetal relationship: is successful pregnancy a Th2 phenomenon? Immunol. Today 14, 353-356 (1993).
    • (1993) Immunol. Today , vol.14 , pp. 353-356
    • Wegmann, T.G.1    Lin, H.2    Guilbert, L.3    Mosmann, T.R.4
  • 12
    • 0037230928 scopus 로고    scopus 로고
    • Immunity to liver stage malaria: Considerations for vaccine design
    • Taylor-Robinson AW. Immunity to liver stage malaria: considerations for vaccine design. Immunol. Res. 27, 13-29 (2002). Useful summary of recent research on immunity to the intrahepatic malaria parasite, especially the role of LSA-1 as a vaccine candidate molecule.
    • (2002) Immunol. Res. , vol.27 , pp. 13-29
    • Taylor-Robinson, A.W.1
  • 13
    • 0015699215 scopus 로고
    • Immunization of man against sporozite-induced falciparum malaria
    • Clyde DF, Most H, McCarthy VC, Vanderberg JP. Immunization of man against sporozite-induced falciparum malaria. Am. J. Med Sci. 266, 169-177 (1973).
    • (1973) Am. J. Med Sci. , vol.266 , pp. 169-177
    • Clyde, D.F.1    Most, H.2    McCarthy, V.C.3    Vanderberg, J.P.4
  • 14
    • 0037090258 scopus 로고    scopus 로고
    • Protection of humans against malaria by immunization with radiation-attenuated Plasmodium falciparum sporozoites
    • Hoffman SL, Goh LM, Luke TC et al. Protection of humans against malaria by immunization with radiation-attenuated Plasmodium falciparum sporozoites. J. Infect. Dis. 185, 1155-1164 (2002).
    • (2002) J. Infect. Dis. , vol.185 , pp. 1155-1164
    • Hoffman, S.L.1    Goh, L.M.2    Luke, T.C.3
  • 15
    • 0014202885 scopus 로고
    • Protective immunity produced by the injection of x-irradiated sporozoites of Plasmodium berghei
    • Nussenzweig RS, Vanderberg J, Most H, Orton C. Protective immunity produced by the injection of x-irradiated sporozoites of Plasmodium berghei. Nature 216, 160-162 (1967).
    • (1967) Nature , vol.216 , pp. 160-162
    • Nussenzweig, R.S.1    Vanderberg, J.2    Most, H.3    Orton, C.4
  • 16
    • 0028201732 scopus 로고
    • Tolerance, danger and the extended family
    • Matzinger P. Tolerance, danger and the extended family. Annu. Rev. Immunol. 12, 991-1045 (1994).
    • (1994) Annu. Rev. Immunol. , vol.12 , pp. 991-1045
    • Matzinger, P.1
  • 17
    • 0002420763 scopus 로고    scopus 로고
    • Why does Plasmodium have a pre-erythrocytic cycle?
    • Rajan TV. Why does Plasmodium have a pre-erythrocytic cycle? Parasitol. Today 13, 284-286 (1997).
    • (1997) Parasitol. Today , vol.13 , pp. 284-286
    • Rajan, T.V.1
  • 18
    • 0001963074 scopus 로고    scopus 로고
    • Malaria and the liver: Tolerance and immunity to attenuated plasmodia sporozoites
    • Crispe IN (Ed.), Wiley-Liss, New York, NY, USA
    • Krzych U, Guebre-Xabier M, Schwenk R. Malaria and the liver: tolerance and immunity to attenuated plasmodia sporozoites. In: T-lymphocytes in the Liver: Immunobiology, Pathology and Host Defense. Crispe IN (Ed.), Wiley-Liss, New York, NY, USA, 163-195 (1999). Considers the evidence for and against the liver as an immunologically privileged site for Plasmodium survival.
    • (1999) T-lymphocytes in the Liver: Immunobiology, Pathology and Host Defense , pp. 163-195
    • Krzych, U.1    Guebre-Xabier, M.2    Schwenk, R.3
  • 19
    • 0026471097 scopus 로고
    • Molecular analysis of the association of HLA-B53 and resistance to severe malaria
    • Hill AVS, Elvin J, Willis AC et al. Molecular analysis of the association of HLA-B53 and resistance to severe malaria. Nature 360, 434-439 (1992). Reveals the association between the human leukocyte antigen HLA-B53 that is common in West Africans and resistance to severe P. falcifarum malaria.
    • (1992) Nature , vol.360 , pp. 434-439
    • Hill, A.V.S.1    Elvin, J.2    Willis, A.C.3
  • 20
    • 0025913521 scopus 로고
    • Common west African HLA antigens are associated with protection from severe malaria
    • + T- cell-dependent protective immunity to an exoerythrocytic antigen of P. falciparum.
    • (1991) Nature , vol.352 , pp. 595-600
    • Hill, A.V.S.1    Allsopp, C.E.2    Kwiatkowski, D.3
  • 21
    • 0030297312 scopus 로고    scopus 로고
    • Strange brew: T-cells in the liver
    • Crispe IN, Mehal WZ. Strange brew: T-cells in the liver. Immunol. Today 17, 522-525 (1996).
    • (1996) Immunol. Today , vol.17 , pp. 522-525
    • Crispe, I.N.1    Mehal, W.Z.2
  • 22
    • 0036094686 scopus 로고    scopus 로고
    • Effects of irradiation on Plasmodium falciparum sporozoite hepatic development: Implications for the design of pre-erythrocytic malaria vaccines
    • Silvie O, Semblat JP, Franetich JF, Hannoun L, Eling W, Mazier D. Effects of irradiation on Plasmodium falciparum sporozoite hepatic development: implications for the design of pre-erythrocytic malaria vaccines. Parasite Immunol. 24, 221-223 (2002).
    • (2002) Parasite Immunol. , vol.24 , pp. 221-223
    • Silvie, O.1    Semblat, J.P.2    Franetich, J.F.3    Hannoun, L.4    Eling, W.5    Mazier, D.6
  • 23
    • 0019890244 scopus 로고
    • In vitro culture of the exoerythrocytic stage of Plasmodium berghei from sporozoites
    • Hollingdale MR, Leef JL, McCullough M, Beaudoin RL. In vitro culture of the exoerythrocytic stage of Plasmodium berghei from sporozoites. Science 213, 1021-1022 (1981).
    • (1981) Science , vol.213 , pp. 1021-1022
    • Hollingdale, M.R.1    Leef, J.L.2    McCullough, M.3    Beaudoin, R.L.4
  • 24
    • 0037083712 scopus 로고    scopus 로고
    • Researchers crack malaria genome
    • Enserink M, Pennisi E. Researchers crack malaria genome. Science 295, 1207 (2002).
    • (2002) Science , vol.295 , pp. 1207
    • Enserink, M.1    Pennisi, E.2
  • 27
    • 0027457377 scopus 로고
    • Malaria circumsporozoite protein binds to heparan sulfate proteoglycans associated with the surface membrane of hepatocytes
    • Frevert U, Sinnis P, Cerami C, Shreffler W, Takacs B, Nussenzweig V. Malaria circumsporozoite protein binds to heparan sulfate proteoglycans associated with the surface membrane of hepatocytes. J. Exp. Med. 177, 1287-1298 (1993).
    • (1993) J. Exp. Med. , vol.177 , pp. 1287-1298
    • Frevert, U.1    Sinnis, P.2    Cerami, C.3    Shreffler, W.4    Takacs, B.5    Nussenzweig, V.6
  • 28
    • 0027326632 scopus 로고
    • Thrombospondin-related anonymous protein of Plasdmodium falciparum binds specifically to sulfated glycoconjugates and to HepG2 hepatoma cells, suggesting a role for this molecule in sporozoite invasion of hepatocytes
    • Müller HM, Reckmann I, Hollingdale MR, Bujard H, Robson KJ, Crisanti A. Thrombospondin-related anonymous protein of Plasdmodium falciparum binds specifically to sulfated glycoconjugates and to HepG2 hepatoma cells, suggesting a role for this molecule in sporozoite invasion of hepatocytes. EMBO J. 12, 2881-2889 (1993).
    • (1993) EMBO J. , vol.12 , pp. 2881-2889
    • Müller, H.M.1    Reckmann, I.2    Hollingdale, M.R.3    Bujard, H.4    Robson, K.J.5    Crisanti, A.6
  • 30
    • 0022509728 scopus 로고
    • Fine structure of the liver forms of the malaria parasite Plasmodium falciparum in human hepatocytes in vitro
    • Meis JFGM, Verhave JP, Ponnudurai T et al. Fine structure of the liver forms of the malaria parasite Plasmodium falciparum in human hepatocytes in vitro. Cell Tissue Res. 244, 345-350 (1985).
    • (1985) Cell Tissue Res. , vol.244 , pp. 345-350
    • Meis, J.F.G.M.1    Verhave, J.P.2    Ponnudurai, T.3
  • 31
    • 0021717145 scopus 로고
    • Ultrastructure of in vitro cultured exoerythrocytic stage of Plasmodium berghei in a hepatoma cell line
    • Aikawa M, Schwartz AL, Uni S, Nussenzweig RS, Hollingdale MR. Ultrastructure of in vitro cultured exoerythrocytic stage of Plasmodium berghei in a hepatoma cell line. Am. J. Trop. Med. Hyg. 33, 792-799 (1984).
    • (1984) Am. J. Trop. Med. Hyg. , vol.33 , pp. 792-799
    • Aikawa, M.1    Schwartz, A.L.2    Uni, S.3    Nussenzweig, R.S.4    Hollingdale, M.R.5
  • 32
    • 0024406930 scopus 로고
    • Expression of Plasmodium berghei circumsporozoite protein on the surface of exoerythrocytic schizonts and merozoites
    • Atkinson CT, Aley SB, Hollingdale MR, Aikawa M. Expression of Plasmodium berghei circumsporozoite protein on the surface of exoerythrocytic schizonts and merozoites. Am. J. Trop. Med. Hyg. 41, 9-17 (1989).
    • (1989) Am. J. Trop. Med. Hyg. , vol.41 , pp. 9-17
    • Atkinson, C.T.1    Aley, S.B.2    Hollingdale, M.R.3    Aikawa, M.4
  • 33
    • 0025363462 scopus 로고
    • A malaria-heat-shock-like determinant expressed on the infected hepatocyte surface is a target of antibody-dependent cell-mediated cytotoxic mechanisms by nonparenchymal liver cells
    • Renia L, Mattei D, Gonna J et al. A malaria-heat-shock-like determinant expressed on the infected hepatocyte surface is a target of antibody-dependent cell-mediated cytotoxic mechanisms by nonparenchymal liver cells. Eur. J. Immunol. 20, 1445-1449 (1990).
    • (1990) Eur. J. Immunol. , vol.20 , pp. 1445-1449
    • Renia, L.1    Mattei, D.2    Gonna, J.3
  • 34
    • 0022521130 scopus 로고
    • Observations on early and late post-sporozoite tissue stages in primate malaria. IV. Pre-erythrocytic schizonts and/or hypnozoites of Chesson and North Korean strains of Plasmodium vivax in the chimpanzee
    • Krotoski WA, Garnham PCC, Cogswell FB et al. Observations on early and late post-sporozoite tissue stages in primate malaria. IV. Pre-erythrocytic schizonts and/or hypnozoites of Chesson and North Korean strains of Plasmodium vivax in the chimpanzee. Am. J. Trop. Med. Hyg. 35, 263-274 (1986).
    • (1986) Am. J. Trop. Med. Hyg. , vol.35 , pp. 263-274
    • Krotoski, W.A.1    Garnham, P.C.C.2    Cogswell, F.B.3
  • 35
    • 0021170248 scopus 로고
    • In vitro infectivity of irradiated P. berghei sporozoites to cultured hepatoma cells
    • Sigler CL, Leland P, Hollingdale MR. In vitro infectivity of irradiated P. berghei sporozoites to cultured hepatoma cells. Am. J. Trop. Med. Hyg. 33, 544-547 (1984).
    • (1984) Am. J. Trop. Med. Hyg. , vol.33 , pp. 544-547
    • Sigler, C.L.1    Leland, P.2    Hollingdale, M.R.3
  • 36
    • 0025358702 scopus 로고
    • Stage-specific ribosomal RNA expression switched during sporozoite invasion of hepatocytes
    • Zhu J, Waters AP, Appiah A, McCutchan TF, Lal AA, Hollingdale MR. Stage-specific ribosomal RNA expression switched during sporozoite invasion of hepatocytes. J. Biol. Chem. 21, 12740-12744 (1990).
    • (1990) J. Biol. Chem. , vol.21 , pp. 12740-12744
    • Zhu, J.1    Waters, A.P.2    Appiah, A.3    McCutchan, T.F.4    Lal, A.A.5    Hollingdale, M.R.6
  • 37
    • 0029031772 scopus 로고
    • Maintenance of protective immunity against malaria by persistent hepatic parasites derived from irradiated sporozoites
    • Scheller LF, Azad AF. Maintenance of protective immunity against malaria by persistent hepatic parasites derived from irradiated sporozoites. Proc. Natl Acad. Sci. USA 92, 4066-4068 (1995).
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 4066-4068
    • Scheller, L.F.1    Azad, A.F.2
  • 38
    • 0023202813 scopus 로고
    • A liver stage-specific antigen of Plasmodium falciparum characterized by gene cloning
    • Guérin-Marchand C, Druilhe P, Galey B et al. A liver stage-specific antigen of Plasmodium falciparum characterized by gene cloning. Nature 329, 164-167 (1987).
    • (1987) Nature , vol.329 , pp. 164-167
    • Guérin-Marchand, C.1    Druilhe, P.2    Galey, B.3
  • 39
    • 0025799806 scopus 로고
    • Structure of Plasmodium falciparum liver stage antigen-1
    • Zhu J, Hollingdale MR. Structure of Plasmodium falciparum liver stage antigen-1. Mol. Biochem. Parasitol. 48, 223-226 (1991).
    • (1991) Mol. Biochem. Parasitol. , vol.48 , pp. 223-226
    • Zhu, J.1    Hollingdale, M.R.2
  • 40
    • 0028276443 scopus 로고
    • Plasmodium falciparum liver stage antigen-1 is well conserved and contains potent B and T-cell determinants
    • Fidock DA, Gras Masse H, Lepers JP et al. Plasmodium falciparum liver stage antigen-1 is well conserved and contains potent B and T-cell determinants. J. Immunol. 153, 190-204 (1994).
    • (1994) J. Immunol. , vol.153 , pp. 190-204
    • Fidock, D.A.1    Gras Masse, H.2    Lepers, J.P.3
  • 42
    • 0018627235 scopus 로고
    • Exoerythrocytic merozoites of Plasmodium berghei in rat hepatic Kupffer cells
    • Terzakis JA, Vanderberg JP, Foley D, Shustak S. Exoerythrocytic merozoites of Plasmodium berghei in rat hepatic Kupffer cells. J. Protozool. 26, 385-389 (1979).
    • (1979) J. Protozool. , vol.26 , pp. 385-389
    • Terzakis, J.A.1    Vanderberg, J.P.2    Foley, D.3    Shustak, S.4
  • 43
    • 0026629038 scopus 로고
    • Localization of a 230 kDa parasitophorous vacuole membrane antigen of Plasmodium berghei exoerythrocytic schizonts (LSA-2) by immunoelectron and confocal laser scanning microscopy
    • Atkinson CT, Hollingdale MR, Aikawa M. Localization of a 230 kDa parasitophorous vacuole membrane antigen of Plasmodium berghei exoerythrocytic schizonts (LSA-2) by immunoelectron and confocal laser scanning microscopy. Am. J. Trop. Med. Hyg. 46, 533-537 (1992).
    • (1992) Am. J. Trop. Med. Hyg. , vol.46 , pp. 533-537
    • Atkinson, C.T.1    Hollingdale, M.R.2    Aikawa, M.3
  • 44
    • 0033985760 scopus 로고    scopus 로고
    • Analysis of immune responses against T- and B-cell epitopes from Plasmodium falciparum liver-stage antigen 1 in rodent malaria models and malaria-exposed human subjects in India
    • Joshi SK, Bharadwaj A, Chatterjee S, Chauchan VS. Analysis of immune responses against T- and B-cell epitopes from Plasmodium falciparum liver-stage antigen 1 in rodent malaria models and malaria-exposed human subjects in India. Infect. Immun. 68, 141-150 (2000).
    • (2000) Infect. Immun. , vol.68 , pp. 141-150
    • Joshi, S.K.1    Bharadwaj, A.2    Chatterjee, S.3    Chauchan, V.S.4
  • 45
    • 0033710323 scopus 로고    scopus 로고
    • Protection against Plasmodium falciparum malaria in chimpanzees by immunization with the conserved pre-erythrocytic liverstage antigen 3
    • Daubersies P, Thomas AW, Millet P et al. Protection against Plasmodium falciparum malaria in chimpanzees by immunization with the conserved pre-erythrocytic liverstage antigen 3. Nat. Med. 6, 1258-1263 (2000). In chimpanzees, which share a susceptability to P. falciparum liver-stage infection with humans, immunization with LSA-3 induced protection against sporozite challenge.
    • (2000) Nat. Med. , vol.6 , pp. 1258-1263
    • Daubersies, P.1    Thomas, A.W.2    Millet, P.3
  • 46
    • 0030584780 scopus 로고    scopus 로고
    • A novel Plasmodium falciparum sporozoite and liver stage antigen (SALSA) defines major B, T-helper and CTL epitopes
    • Bottius E, Mohamed L, Brahimi K et al. A novel Plasmodium falciparum sporozoite and liver stage antigen (SALSA) defines major B, T-helper and CTL epitopes. J. Immunol. 156, 2874-2884 (1996).
    • (1996) J. Immunol. , vol.156 , pp. 2874-2884
    • Bottius, E.1    Mohamed, L.2    Brahimi, K.3
  • 48
    • 0029058866 scopus 로고
    • Plasmodium yoelii: 17-kDa hepatic and erythrocytic stage protein is the target of an inhibitory monoclonal antibody
    • Charoenvit Y, Mellouk S, Sedegah M et al. Plasmodium yoelii: 17-kDa hepatic and erythrocytic stage protein is the target of an inhibitory monoclonal antibody. Exp. Parasitol. 80, 419-429 (1995).
    • (1995) Exp. Parasitol. , vol.80 , pp. 419-429
    • Charoenvit, Y.1    Mellouk, S.2    Sedegah, M.3
  • 49
    • 0022431819 scopus 로고
    • The gene for an exported antigen of the malaria parasite Plasmodium falciparum cloned and expressed in Escherichia coli
    • Hope IA, Mackay M, Hyde JE, Goman M, Scaife J. The gene for an exported antigen of the malaria parasite Plasmodium falciparum cloned and expressed in Escherichia coli. Nucleic Acids Res. 13, 369-379 (1985).
    • (1985) Nucleic Acids Res. , vol.13 , pp. 369-379
    • Hope, I.A.1    Mackay, M.2    Hyde, J.E.3    Goman, M.4    Scaife, J.5
  • 51
    • 0027323768 scopus 로고
    • P. berghei sporozoite immunization protects against P. berghei sporozoite infection
    • Sina BJ, do Rosario VE, Woollett G, Hollingdale MR. P. berghei sporozoite immunization protects against P. berghei sporozoite infection. Exp. Parasitol. 77, 129-135 (1993).
    • (1993) Exp. Parasitol. , vol.77 , pp. 129-135
    • Sina, B.J.1    Do Rosario, V.E.2    Woollett, G.3    Hollingdale, M.R.4
  • 52
    • 0026876582 scopus 로고
    • A protective monoclonal antibody with dual specificity for Plasmodium falciparum and P. berghei circumsporozoite proteins
    • Sina BJ, Wright C, Ballou WR, Hollingdale MR. A protective monoclonal antibody with dual specificity for Plasmodium falciparum and P. berghei circumsporozoite proteins. Exp. Parasitol. 74, 431-440 (1992).
    • (1992) Exp. Parasitol. , vol.74 , pp. 431-440
    • Sina, B.J.1    Wright, C.2    Ballou, W.R.3    Hollingdale, M.R.4
  • 53
    • 0027513002 scopus 로고
    • Expression of heat shock proteins (members of the hsp70 family) in the hepatic stages of Plasmodium falciparum and P. berghei
    • Kumar N, Nagasawa H, Sacci JB et al. Expression of heat shock proteins (members of the hsp70 family) in the hepatic stages of Plasmodium falciparum and P. berghei. Parasitol. Res. 79, 109-113 (1993).
    • (1993) Parasitol. Res. , vol.79 , pp. 109-113
    • Kumar, N.1    Nagasawa, H.2    Sacci, J.B.3
  • 54
    • 0023882451 scopus 로고
    • Mature liver stages of cloned Plasmodium falciparum share epitopes with proteins from sporozoites and asexual blood stages
    • Szarfman A, Lyon JA, Walliker D et al. Mature liver stages of cloned Plasmodium falciparum share epitopes with proteins from sporozoites and asexual blood stages. Parasite Immunol. 10, 339-351 (1988).
    • (1988) Parasite Immunol. , vol.10 , pp. 339-351
    • Szarfman, A.1    Lyon, J.A.2    Walliker, D.3
  • 55
    • 0024353079 scopus 로고
    • Th1 and Th2 cells: Different patterns of lymphokine secretion lead to different functional properties
    • Mosmann TR, Coffman RL. Th1 and Th2 cells: different patterns of lymphokine secretion lead to different functional properties. Annu. Rev. Immunol. 7, 145-173 (1989).
    • (1989) Annu. Rev. Immunol. , vol.7 , pp. 145-173
    • Mosmann, T.R.1    Coffman, R.L.2
  • 56
    • 0029928417 scopus 로고    scopus 로고
    • The expanding universe of T-cell subsets: Th1, Th2 and more
    • Mosmann TR, Sad S. The expanding universe of T-cell subsets: Th1, Th2 and more. Immunol. Today 17, 138-146 (1996).
    • (1996) Immunol. Today , vol.17 , pp. 138-146
    • Mosmann, T.R.1    Sad, S.2
  • 57
    • 0022508711 scopus 로고
    • Interferon-γ inhibits the action of B-cell stimulatory factor-1 on resting B-cells
    • Rabin EM, Mond JJ, Ohara J, Paul WE. Interferon-γ inhibits the action of B-cell stimulatory factor-1 on resting B-cells. J. Immunol. 137, 1573-1576 (1986).
    • (1986) J. Immunol. , vol.137 , pp. 1573-1576
    • Rabin, E.M.1    Mond, J.J.2    Ohara, J.3    Paul, W.E.4
  • 59
    • 0023726937 scopus 로고
    • Antiproliferative effect of IFN-γ in immune regulation. IFN-γ inhibits the proliferation of Th2 but not Th1 murine helper T-lymphocyte clones
    • Gajewski TF, Fitch FW. Antiproliferative effect of IFN-γ in immune regulation. IFN-γ inhibits the proliferation of Th2 but not Th1 murine helper T-lymphocyte clones. J. Immunol. 140, 4245-4252 (1988).
    • (1988) J. Immunol. , vol.140 , pp. 4245-4252
    • Gajewski, T.F.1    Fitch, F.W.2
  • 60
    • 0030746897 scopus 로고    scopus 로고
    • Th1-Th2: Reliable paradigm or dangerous dogma?
    • Allen JE, Maizels RM. Th1-Th2: reliable paradigm or dangerous dogma? Immunol. Today 18, 387-392 (1997).
    • (1997) Immunol. Today , vol.18 , pp. 387-392
    • Allen, J.E.1    Maizels, R.M.2
  • 61
    • 0029557309 scopus 로고
    • Interleukin-12: A pro-inflammatory cytokine with immunoregulatory functions
    • Trinchieri G, Scott P. Interleukin-12: a pro-inflammatory cytokine with immunoregulatory functions. Res. Immunol. 146, 423-431 (1995).
    • (1995) Res. Immunol. , vol.146 , pp. 423-431
    • Trinchieri, G.1    Scott, P.2
  • 62
    • 0026691714 scopus 로고
    • Regulation of human cytolytic lymphocyte responses by interleukin-12
    • Gately MK, Wolitzky AG, Quinn PM, Chizzonite R. Regulation of human cytolytic lymphocyte responses by interleukin-12. Cell. Immunol. 143, 127-142 (1992).
    • (1992) Cell. Immunol. , vol.143 , pp. 127-142
    • Gately, M.K.1    Wolitzky, A.G.2    Quinn, P.M.3    Chizzonite, R.4
  • 64
    • 0028037226 scopus 로고
    • Interleukin-12 induction of interferon gamma-dependent protection against malaria
    • Sedegah M, Finkelman F, Hoffman SL. Interleukin-12 induction of interferon gamma-dependent protection against malaria. Proc. Natl Acad. Sci. USA 91, 10700-10702 (1994). Indicates that IL-12 stimulates non-B, non-T-cells to produce IFN-γ that kills intrahepatic parasites by stimulating NO production.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 10700-10702
    • Sedegah, M.1    Finkelman, F.2    Hoffman, S.L.3
  • 65
    • 0033178522 scopus 로고    scopus 로고
    • Immune effector mechanisms in malaria
    • Good MF, Doolan DL. Immune effector mechanisms in malaria. Curr. Opin. Immunol. 11, 412-419 (1999).
    • (1999) Curr. Opin. Immunol. , vol.11 , pp. 412-419
    • Good, M.F.1    Doolan, D.L.2
  • 66
    • 0034254649 scopus 로고    scopus 로고
    • The complexity of protective immunity against liver-stage malaria
    • Doolan DL, Hoffman SL. The complexity of protective immunity against liver-stage malaria. J. Immunol. 165, 1453-1462 (2000).
    • (2000) J. Immunol. , vol.165 , pp. 1453-1462
    • Doolan, D.L.1    Hoffman, S.L.2
  • 67
    • 0021368476 scopus 로고
    • Inhibition of entry of Plasmodium falciparum and P. vivax sporozoites into cultured cells; an in vitro assay of protective antibodies
    • Hollingdale MR, Nardin EH, Tharavanij S, Schwartz AL, Nussenzweig RS. Inhibition of entry of Plasmodium falciparum and P. vivax sporozoites into cultured cells; an in vitro assay of protective antibodies. J. Immunol. 132, 909-913 (1984).
    • (1984) J. Immunol. , vol.132 , pp. 909-913
    • Hollingdale, M.R.1    Nardin, E.H.2    Tharavanij, S.3    Schwartz, A.L.4    Nussenzweig, R.S.5
  • 68
    • 0018891152 scopus 로고
    • Hybridoma produces antibodies directed against the sporozoite stage of malaria parasite
    • Yoshida N, Nussenzweig RS, Potocnjak P, Nussenzweig V, Aikawa M. Hybridoma produces antibodies directed against the sporozoite stage of malaria parasite. Science 207, 71-73 (1980).
    • (1980) Science , vol.207 , pp. 71-73
    • Yoshida, N.1    Nussenzweig, R.S.2    Potocnjak, P.3    Nussenzweig, V.4    Aikawa, M.5
  • 69
    • 0029097457 scopus 로고
    • T-lymphocytes from volunteers immunized with irradiated Plasmodium falciparum sporozoites recognize liver and blood stage antigens
    • Krzych U, Lyon J, Jareed T et al. T-lymphocytes from volunteers immunized with irradiated Plasmodium falciparum sporozoites recognize liver and blood stage antigens. J. Immunol. 155, 4072-4077 (1995).
    • (1995) J. Immunol. , vol.155 , pp. 4072-4077
    • Krzych, U.1    Lyon, J.2    Jareed, T.3
  • 70
    • 0023869487 scopus 로고
    • Human T-cell recognition of the circumsporozoite protein of Plasmodium falciparum: Immunodominant T-cell domains map to the polymorphic regions of the molecule
    • Good MF, Pombo D, Quakyi I et al. Human T-cell recognition of the circumsporozoite protein of Plasmodium falciparum: immunodominant T-cell domains map to the polymorphic regions of the molecule. Proc. Natl Acad. Sci. USA 85, 1199-1203 (1987).
    • (1987) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 1199-1203
    • Good, M.F.1    Pombo, D.2    Quakyi, I.3
  • 71
    • 0028276443 scopus 로고
    • Plasmodium falciparum liver stage antigen-1 is well conserved and contains potent B and T-cell determinants
    • Fidock DA, Gras-Masse H, Lepers JP et al. Plasmodium falciparum liver stage antigen-1 is well conserved and contains potent B and T-cell determinants. J. Immunol. 153, 190-204 (1994).
    • (1994) J. Immunol. , vol.153 , pp. 190-204
    • Fidock, D.A.1    Gras-Masse, H.2    Lepers, J.P.3
  • 72
    • 0024413594 scopus 로고
    • Sporozoite vaccine induces genetically restricted T-cell elimination of malaria from hepatocytes
    • Hoffman SL, Isenbarger D, Long G et al. Sporozoite vaccine induces genetically restricted T-cell elimination of malaria from hepatocytes. Science 244, 1078-1081 (1989).
    • (1989) Science , vol.244 , pp. 1078-1081
    • Hoffman, S.L.1    Isenbarger, D.2    Long, G.3
  • 75
    • 0026675372 scopus 로고
    • A T-cell done directed at the circurmsporozoite protein which protects mice against both Plasmodium yoelii and P. berghei
    • Weiss WR, Berzofsky JA, Houghten RA, Sedegah M, Hollingdale MR, Hoffman SL. A T-cell done directed at the circurmsporozoite protein which protects mice against both Plasmodium yoelii and P. berghei. J. Immunol. 149, 2103-2109 (1992).
    • (1992) J. Immunol. , vol.149 , pp. 2103-2109
    • Weiss, W.R.1    Berzofsky, J.A.2    Houghten, R.A.3    Sedegah, M.4    Hollingdale, M.R.5    Hoffman, S.L.6
  • 76
    • 37049185845 scopus 로고
    • Inhibition of development of exoerythrocytic forms of malaria parasites by gamma-interferon
    • Ferreira A, Schofield L, Enea V et al. Inhibition of development of exoerythrocytic forms of malaria parasites by gamma-interferon. Science 232, 881-884 (1986).
    • (1986) Science , vol.232 , pp. 881-884
    • Ferreira, A.1    Schofield, L.2    Enea, V.3
  • 78
    • 0025761982 scopus 로고
    • IFN-gamma inhibits development of Plasmodium berghei exoerythrocytic stages in hepatocytes by an L-arginine-dependent effector mechanism
    • Mellouk S, Green SJ, Nacy CA, Hoffman SI. IFN-gamma inhibits development of Plasmodium berghei exoerythrocytic stages in hepatocytes by an L-arginine-dependent effector mechanism J. Immunol. 146, 3971-3976 (1991).
    • (1991) J. Immunol. , vol.146 , pp. 3971-3976
    • Mellouk, S.1    Green, S.J.2    Nacy, C.A.3    Hoffman, S.I.4
  • 80
    • 16944364593 scopus 로고    scopus 로고
    • Sterile protection of monkeys against malaria after administration of interleukin-12
    • Hoffman SL, Crutcher JM, Puff SK et al. Sterile protection of monkeys against malaria after administration of interleukin-12. Nat. Med. 3, 80-83 (1997).
    • (1997) Nat. Med. , vol.3 , pp. 80-83
    • Hoffman, S.L.1    Crutcher, J.M.2    Puff, S.K.3
  • 81
    • 0001153209 scopus 로고    scopus 로고
    • Polymorphism in promoter region of inducible nitric oxide synthase gene and protection against malaria
    • Kun JFJ, Lell B, Lehman LG, Luckner D, Kremsner PG. Polymorphism in promoter region of inducible nitric oxide synthase gene and protection against malaria. Lancet 351, 265 (1998). Expression of an iNOS gene mutation is inversely proportional to the severity of clinical P. falciparum. Provides correlative support for NO-mediated protection.
    • (1998) Lancet , vol.351 , pp. 265
    • Kun, J.F.J.1    Lell, B.2    Lehman, L.G.3    Luckner, D.4    Kremsner, P.G.5
  • 82
    • 0027937745 scopus 로고
    • Cytolytic T-cell cytotoxicity is mediated through perforin and Fas lytic pathways
    • Lowin B, Hahne M, Mattmann C, Tschopp J. Cytolytic T-cell cytotoxicity is mediated through perforin and Fas lytic pathways. Nature 370, 650-652 (1994).
    • (1994) Nature , vol.370 , pp. 650-652
    • Lowin, B.1    Hahne, M.2    Mattmann, C.3    Tschopp, J.4
  • 83
    • 0030929615 scopus 로고    scopus 로고
    • Elimination of P. berghei liver stages is independent of Fas (CD95/Apo-I) or perforin-mediated cytotoxicity
    • Renggli J, Hahne M, Matile H, Betschart B, Tschopp J, Corradin G. Elimination of P. berghei liver stages is independent of Fas (CD95/Apo-I) or perforin-mediated cytotoxicity. Parasite Immunol. 19, 145-148 (1997).
    • (1997) Parasite Immunol. , vol.19 , pp. 145-148
    • Renggli, J.1    Hahne, M.2    Matile, H.3    Betschart, B.4    Tschopp, J.5    Corradin, G.6
  • 84
    • 0029421460 scopus 로고
    • Perforin- and Fas-mediated cytotoxic pathways are not required for allogeneic resistance to bone marrow grafts in mice
    • Baker MB, Podack ER, Levy RB. Perforin- and Fas-mediated cytotoxic pathways are not required for allogeneic resistance to bone marrow grafts in mice. Biol. Blood Marrow Transplant. 1, 69-73 (1995).
    • (1995) Biol. Blood Marrow Transplant. , vol.1 , pp. 69-73
    • Baker, M.B.1    Podack, E.R.2    Levy, R.B.3
  • 85
    • 0033914763 scopus 로고    scopus 로고
    • Central role of endogenous gamma interferon in protective immunity against blood-stage Plasmodium chabaudi AS infection
    • Su Z, Stevenson MM. Central role of endogenous gamma interferon in protective immunity against blood-stage Plasmodium chabaudi AS infection. Infect. Immun. 68, 4399-4406 (2000).
    • (2000) Infect. Immun. , vol.68 , pp. 4399-4406
    • Su, Z.1    Stevenson, M.M.2
  • 88
    • 0031202831 scopus 로고    scopus 로고
    • Binding of malaria T-cell epitopes to DR and DQ molecules in vitro correlates with immunogenicity in vivo: Identification of a universal T-cell epitope in the Plasmodium falciparum circumsporozoite protein
    • Calvo-Calle JM, Hammer J, Sinigaglia F, Clavijo P, Moya-Castro ZR, Nardin EH. Binding of malaria T-cell epitopes to DR and DQ molecules in vitro correlates with immunogenicity in vivo: identification of a universal T-cell epitope in the Plasmodium falciparum circumsporozoite protein. J. Immunol. 159, 1362-1373 (1997).
    • (1997) J. Immunol. , vol.159 , pp. 1362-1373
    • Calvo-Calle, J.M.1    Hammer, J.2    Sinigaglia, F.3    Clavijo, P.4    Moya-Castro, Z.R.5    Nardin, E.H.6
  • 90
    • 0033621811 scopus 로고    scopus 로고
    • Gamma delta T-cells are a component of early immunity against preerythrocytic malaria parasites
    • McKenna KC, Tsuji M, Sarzotti M, Sacci JB, Witney AA, Azad AF. Gamma delta T-cells are a component of early immunity against preerythrocytic malaria parasites. Infect. Immun. 68, 2224-2230 (2000). Demonstrates that the γδT-cell is a distinct component of early immunity to pre-erythrocytic parasites.
    • (2000) Infect. Immun. , vol.68 , pp. 2224-2230
    • McKenna, K.C.1    Tsuji, M.2    Sarzotti, M.3    Sacci, J.B.4    Witney, A.A.5    Azad, A.F.6
  • 91
    • 0029883981 scopus 로고    scopus 로고
    • + T-lymphocytes is required for protective immunity against Plasmodium berghei
    • + T- lymphocytes is required for protective immunity against Plasmodium berghei. J. Immunol. 156, 3374-3381 (1996).
    • (1996) J. Immunol. , vol.156 , pp. 3374-3381
    • White, K.L.1    Link-Snyder, H.2    Krzych, U.3
  • 92
    • 0033182171 scopus 로고    scopus 로고
    • Pre-erythrocytic malaria vaccine: Mechanisms of protective immunity and human vaccine trials
    • Nardin E, Zavala F, Nussenzweig V, Nussenzweig RS. Pre-erythrocytic malaria vaccine: mechanisms of protective immunity and human vaccine trials. Parassitologia 41, 397-402 (1999).
    • (1999) Parassitologia , vol.41 , pp. 397-402
    • Nardin, E.1    Zavala, F.2    Nussenzweig, V.3    Nussenzweig, R.S.4
  • 93
    • 0033200139 scopus 로고    scopus 로고
    • Prometheus through the looking glass: Reflections on the hepatic immune system
    • O'Farrelly C, Crispe IN. Prometheus through the looking glass: reflections on the hepatic immune system. Immunol. Today 20, 394-398 (1999).
    • (1999) Immunol. Today , vol.20 , pp. 394-398
    • O'Farrelly, C.1    Crispe, I.N.2
  • 94
    • 0026327921 scopus 로고
    • Eosinophilrich, granulomatous inflammatory response to Plasmodium berghei hepatic schizonts in non-immunized rats is agerelated
    • Khan ZM, Vanderberg JP. Eosinophilrich, granulomatous inflammatory response to Plasmodium berghei hepatic schizonts in non-immunized rats is agerelated. Am. J. Trop. Med. Hyg. 45, 190-201 (1991).
    • (1991) Am. J. Trop. Med. Hyg. , vol.45 , pp. 190-201
    • Khan, Z.M.1    Vanderberg, J.P.2
  • 95
    • 0028093337 scopus 로고
    • Characterization of liver lymphomyloid cells in mice infected with Plasmodium yoelii sporozoites
    • Faure P, Marussig M, Goosens P, Miltgen F, Mazier D. Characterization of liver lymphomyloid cells in mice infected with Plasmodium yoelii sporozoites. Immunology 82, 645-650 (1994).
    • (1994) Immunology , vol.82 , pp. 645-650
    • Faure, P.1    Marussig, M.2    Goosens, P.3    Miltgen, F.4    Mazier, D.5
  • 96
    • 0028862485 scopus 로고
    • Protective immunity against malaria: Cellular changes in the liver vary according to the method of immunization
    • Faure P, Hukier E, Miltgen F, Renia L, Mazier D. Protective immunity against malaria: Cellular changes in the liver vary according to the method of immunization. Parasite Immunol. 17, 469-477 (1995).
    • (1995) Parasite Immunol. , vol.17 , pp. 469-477
    • Faure, P.1    Hukier, E.2    Miltgen, F.3    Renia, L.4    Mazier, D.5
  • 97
    • 0034037819 scopus 로고    scopus 로고
    • The role of intrahepatic lymphocytes in mediating protective immunity induced by attenuated Plasmodium berghei sporozoites
    • Krzych U, Schwenk R, Guebre-Xabier M et al. The role of intrahepatic lymphocytes in mediating protective immunity induced by attenuated Plasmodium berghei sporozoites. Immunol. Rev. 174, 123-134 (2000).
    • (2000) Immunol. Rev. , vol.174 , pp. 123-134
    • Krzych, U.1    Schwenk, R.2    Guebre-Xabier, M.3
  • 98
    • 0032711933 scopus 로고    scopus 로고
    • + T-cells persist in livers of mice protected against malaria by immunization with attenuated Plasmodium berghei sporozoites
    • + T-cell response to antigenic depots in the liver maintains protection against malaria.
    • (1999) Eur. J. Immunol. , vol.29 , pp. 3978-3986
    • Guebre-Xabier, M.1    Schwenk, R.2    Krzych, U.3
  • 99
    • 0034078355 scopus 로고    scopus 로고
    • The liver as a site of T-cell apoptosis: Graveyard, or killing field?
    • Crispe IN, Dao T Klugewitz K, Mehal WZ, Metz DP. The liver as a site of T-cell apoptosis: graveyard, or killing field? Immunol. Rev. 174, 47-62 (2000).
    • (2000) Immunol. Rev. , vol.174 , pp. 47-62
    • Crispe, I.N.1    Dao, T.2    Klugewitz, K.3    Mehal, W.Z.4    Metz, D.P.5
  • 100
    • 0029072487 scopus 로고
    • + T-cell protective immunity induced by immunization with Plasmodium berghei CS protein-derived synthetic peptides: Evidence that localization of peptide-specific CTLs is crucial for protection against malaria
    • + T-cell protective immunity induced by immunization with Plasmodium berghei CS protein-derived synthetic peptides: evidence that localization of peptide-specific CTLs is crucial for protection against malaria. Immunol. Lett 46, 199-205 (1995).
    • (1995) Immunol. Lett. , vol.46 , pp. 199-205
    • Renggli, J.1    Valmori, D.2    Romero, J.F.3
  • 102
    • 0029122495 scopus 로고
    • + cells: New clues to their origin, specificity and function
    • + cells: New clues to their origin, specificity and function. J. Exp. Med. 182, 633-638 (1995).
    • (1995) J. Exp. Med. , vol.182 , pp. 633-638
    • MacDonald, H.R.1
  • 104
    • 0029011119 scopus 로고
    • + αβ T-cells with intermediary TCR induced in the liver of mice by IL-12
    • + αβ T-cells with intermediary TCR induced in the liver of mice by IL-12. J. Immunol. 154, 4333-4340 (1995).
    • (1995) J. Immunol. , vol.154 , pp. 4333-4340
    • Hashimoto, W.1    Takeda, K.2    Anzai, R.3
  • 105
    • 0033565408 scopus 로고    scopus 로고
    • + T-cells in the Plasmodium yoelii model
    • + T-cells in the Plasmodium yoelii model. J. Immunol. 163, 884-892 (1999).
    • (1999) J. Immunol. , vol.163 , pp. 884-892
    • Doolan, D.L.1    Hoffman, S.L.2
  • 107
    • 0029966335 scopus 로고    scopus 로고
    • + αβ T-cells activated by IL-12 as a major inhibition of experimental tumor metastasis
    • + αβ T-cells activated by IL-12 as a major inhibition of experimental tumor metastasis. J. Immunol. 156, 3366-3373 (1996).
    • (1996) J. Immunol. , vol.156 , pp. 3366-3373
    • Takeda, K.1    Seki, S.2    Ogasawara, K.3
  • 108
    • 0027462422 scopus 로고
    • Immunity to intracellular bacteria
    • Kaufman SHE. Immunity to intracellular bacteria. Annu. Rev. Immunol. 11, 129-163 (1993).
    • (1993) Annu. Rev. Immunol. , vol.11 , pp. 129-163
    • Kaufman, S.H.E.1
  • 110
    • 0031572206 scopus 로고    scopus 로고
    • + T-lymphocytes producing IL-4 in response to antigens on Plasmodium falciparum erythrocytes: An in vitro correlate of protective immunity induced with attenuated Plasmodium falciparum sporozoites
    • + T-lymphocytes producing IL-4 in response to antigens on Plasmodium falciparum erythrocytes: an in vitro correlate of protective immunity induced with attenuated Plasmodium falciparum sporozoites. Cell. Immunol. 180, 143-152 (1997).
    • (1997) Cell. Immunol. , vol.180 , pp. 143-152
    • Bergmann, E.S.1    Ballou, R.W.2    Krzych, U.3
  • 111
    • 0034142340 scopus 로고    scopus 로고
    • + TCR alpha beta intermediate cells increase during experimental malaria infection and are able to exhibit inhibitory activity against the parasite liver stage in vitro
    • + TCR alpha beta intermediate cells increase during experimental malaria infection and are able to exhibit inhibitory activity against the parasite liver stage in vitro. J. Immunol. 164, 1463-1469 (2000).
    • (2000) J. Immunol. , vol.164 , pp. 1463-1469
    • Pied, S.1    Roland, J.2    Louise, A.3
  • 112
    • 0034013026 scopus 로고    scopus 로고
    • Predominance of one T-cell antigen receptor BV haplotype in African populations
    • Craddock TP, Zumla AM, Ollier WE et al. Predominance of one T-cell antigen receptor BV haplotype in African populations. Immunogenetics 51, 231-237 (2000).
    • (2000) Immunogenetics , vol.51 , pp. 231-237
    • Craddock, T.P.1    Zumla, A.M.2    Ollier, W.E.3
  • 113
    • 0030830230 scopus 로고    scopus 로고
    • T-cell immunity to peptide epitopes of liver-stage antigen 1 in an area of Papua New Guinea in which malaria is holoendemic
    • + T-cell-driven IFN-γ responses to conserved epitopes of LSA-1 common in residents of a malaria-endemic region is consistent with a role for this T-cell population in immunity to liver-stage P. falciparum in humans.
    • (1997) Infect. Immun. , vol.65 , pp. 5082-5087
    • Connelly, M.1    King, C.L.2    Bucci, K.3
  • 114
    • 0033775528 scopus 로고    scopus 로고
    • Influence of age and HLA type on IFN-γ responses to a naturally occurring polymorphic epitope of Plasmodium falciparum liver stage antigen-1
    • Bucci K, Kastens W, Hollingdale MR et al. Influence of age and HLA type on IFN-γ responses to a naturally occurring polymorphic epitope of Plasmodium falciparum liver stage antigen-1. Clin. Exp. Immunol. 122, 94-100 (2000). Supports the notions of MHC class I allele selection by malaria and of age-related cumulative exposure increasing the frequency of IFN-γ responses to LSAs.
    • (2000) Clin. Exp. Immunol. , vol.122 , pp. 94-100
    • Bucci, K.1    Kastens, W.2    Hollingdale, M.R.3
  • 115
    • 0033850034 scopus 로고    scopus 로고
    • Cytokine responses to Plasmodium falciparum liverstage antigen 1 vary in rainy and dry seasons in highland Kenya
    • John CC, Sumba PO, Ouma JH, Nahlen BL, King CL, Kazura JW. Cytokine responses to Plasmodium falciparum liverstage antigen 1 vary in rainy and dry seasons in highland Kenya. Infect. Immun. 68, 5198-5204 (2000).
    • (2000) Infect. Immun. , vol.68 , pp. 5198-5204
    • John, C.C.1    Sumba, P.O.2    Ouma, J.H.3    Nahlen, B.L.4    King, C.L.5    Kazura, J.W.6
  • 116
    • 0032948127 scopus 로고    scopus 로고
    • Interferon-gamma responses are associated with resistance to reinfection with Plasmodium falciparum in young African children
    • Luty AJ, Lell B, Schmidt-Ott R et al. Interferon-gamma responses are associated with resistance to reinfection with Plasmodium falciparum in young African children. J. Infect. Dis. 179, 980-988 (1999).
    • (1999) J. Infect. Dis. , vol.179 , pp. 980-988
    • Luty, A.J.1    Lell, B.2    Schmidt-Ott, R.3
  • 117
    • 0034746910 scopus 로고    scopus 로고
    • HLA-DQB1*0501-restricted Th 1 type immune responses to Plasmodium falciparum liver stage antigen 1 protect against malaria anemia and reinfections
    • May J, Lell B, Luty AJ, Meyer CG, Kremsner PG. HLA-DQB1*0501-restricted Th1 type immune responses to Plasmodium falciparum liver stage antigen 1 protect against malaria anemia and reinfections. J. Infect. Dis. 183, 168-172 (2001).
    • (2001) J. Infect. Dis. , vol.183 , pp. 168-172
    • May, J.1    Lell, B.2    Luty, A.J.3    Meyer, C.G.4    Kremsner, P.G.5
  • 118
    • 0033045397 scopus 로고    scopus 로고
    • Interleukin-10 responses to liver-stage antigen 1 predict human resistance to Plasmodium falciparum
    • Kurtis JD, Lanar DE, Opollo M, Duffy PE. Interleukin-10 responses to liver-stage antigen 1 predict human resistance to Plasmodium falciparum. Infect. Immun. 67, 3424-3429 (1999).
    • (1999) Infect. Immun. , vol.67 , pp. 3424-3429
    • Kurtis, J.D.1    Lanar, D.E.2    Opollo, M.3    Duffy, P.E.4
  • 119
    • 0032442755 scopus 로고    scopus 로고
    • Parasite antigen-specific interleukin-10 and antibody responses predict accelerated parasite clearance in Plasmodium falciparum malaria
    • Luty AJ, Lell B, Schmidt-Ott R et al. Parasite antigen-specific interleukin-10 and antibody responses predict accelerated parasite clearance in Plasmodium falciparum malaria. Eur. Cytokine Netw. 9, 639-646 (1998).
    • (1998) Eur. Cytokine Netw. , vol.9 , pp. 639-646
    • Luty, A.J.1    Lell, B.2    Schmidt-Ott, R.3
  • 120
    • 0033375692 scopus 로고    scopus 로고
    • Factors influencing resistance to reinfection with Plasmodium falciparum
    • Domarle O, Migot-Nabias F, Mvoukani JL et al. Factors influencing resistance to reinfection with Plasmodium falciparum. Am. J. Trop. Med. Hyg. 61, 926-931 (1999).
    • (1999) Am. J. Trop. Med. Hyg. , vol.61 , pp. 926-931
    • Domarle, O.1    Migot-Nabias, F.2    Mvoukani, J.L.3
  • 121
    • 0033790473 scopus 로고    scopus 로고
    • Immune response to Plasmodium falciparum liver stage antigen-1: Geographical variations within Central Africa and their relationship with protection from clinical malaria
    • Migot-Nabias F, Deloron P, Ringwald P et al. Immune response to Plasmodium falciparum liver stage antigen-1: geographical variations within Central Africa and their relationship with protection from clinical malaria. Trans. R. Soc. Trop. Med. Hyg. 94, 557-562 (2000).
    • (2000) Trans. R. Soc. Trop. Med. Hyg. , vol.94 , pp. 557-562
    • Migot-Nabias, F.1    Deloron, P.2    Ringwald, P.3
  • 123
    • 0026584291 scopus 로고
    • Interleukin-10 is a potent growth and differentiation factor for activated human B-lymphocytes
    • Rousset, F, Garcia E, Defrance T et al. Interleukin-10 is a potent growth and differentiation factor for activated human B-lymphocytes. Proc. Natl Acad. Sci. USA 89, 1890-1893 (1992).
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 1890-1893
    • Rousset, F.1    Garcia, E.2    Defrance, T.3
  • 125
    • 0033960941 scopus 로고    scopus 로고
    • Cytotoxic T-lymphocyte epitopes for HLA-B53 and other HLA types in the malaria vaccine candidate liver-stage antigen 3
    • Aidoo M, Lalvani A, Gilbert SC et al. Cytotoxic T-lymphocyte epitopes for HLA-B53 and other HLA types in the malaria vaccine candidate liver-stage antigen 3. Infect. Immun. 68, 227-232 (2000). Emphasizes that an effective pre-erythrocytic vaccine against P. falciparum is likely to require inclusion of components from several exoerythrocytic antigens.
    • (2000) Infect. Immun. , vol.68 , pp. 227-232
    • Aidoo, M.1    Lalvani, A.2    Gilbert, S.C.3
  • 126
    • 0030713016 scopus 로고    scopus 로고
    • Plasmodium falciparum sporozoite invasion is inhibited by naturally acquired or experimentally induced polyclonal antibodies to the STARP antigen
    • Pasquetto V, Fidock DA, Gras H et al. Plasmodium falciparum sporozoite invasion is inhibited by naturally acquired or experimentally induced polyclonal antibodies to the STARP antigen. Eur. J. Immunol. 27, 2502-2513 (1997).
    • (1997) Eur. J. Immunol. , vol.27 , pp. 2502-2513
    • Pasquetto, V.1    Fidock, D.A.2    Gras, H.3
  • 127
    • 0034064657 scopus 로고    scopus 로고
    • Cytophilic immunoglobulin responses to Plasmodium falciparum glutamate-rich protein are correlated with protection against clinical malaria in Dielmo, Senegal
    • Oeuvray C, Theisen M, Rogier C, Trape JF, Jepsen S, Druilhe P. Cytophilic immunoglobulin responses to Plasmodium falciparum glutamate-rich protein are correlated with protection against clinical malaria in Dielmo, Senegal. Infect. Immun. 68, 2617-2620 (2000).
    • (2000) Infect. Immun. , vol.68 , pp. 2617-2620
    • Oeuvray, C.1    Theisen, M.2    Rogier, C.3    Trape, J.F.4    Jepsen, S.5    Druilhe, P.6
  • 128
    • 0031975242 scopus 로고    scopus 로고
    • The glutamate-rich protein (GLURP) of Plasmodium falciparum is a target for antibody-dependent monocyte-mediated inhibition of parasite growth in vitro
    • Theisen M, Soe S, Oeuvray C et al. The glutamate-rich protein (GLURP) of Plasmodium falciparum is a target for antibody-dependent monocyte-mediated inhibition of parasite growth in vitro. Infect. Immun. 66, 11-17 (1998).
    • (1998) Infect. Immun. , vol.66 , pp. 11-17
    • Theisen, M.1    Soe, S.2    Oeuvray, C.3
  • 129
    • 0030200510 scopus 로고    scopus 로고
    • Cloning of a Plasmodium falciparum gene related to the human 60-kDa heat shock protein
    • Syin C, Goldman ND. Cloning of a Plasmodium falciparum gene related to the human 60-kDa heat shock protein. Mol. Biochem. Parasitol. 79, 13-19 (1996).
    • (1996) Mol. Biochem. Parasitol. , vol.79 , pp. 13-19
    • Syin, C.1    Goldman, N.D.2
  • 131
    • 0032738026 scopus 로고    scopus 로고
    • Advances in vaccine adjuvants
    • Singh M, O'Hagan D. Advances in vaccine adjuvants. Nat. Biotechnol. 17, 1075-1081 (1999).
    • (1999) Nat. Biotechnol. , vol.17 , pp. 1075-1081
    • Singh, M.1    O'Hagan, D.2
  • 132
    • 0004170486 scopus 로고    scopus 로고
    • A preliminary evaluation of a recombinant circumsporozoite protein vaccine against Plasmodium falciparum malaria
    • Stoute JA, Slaoui M, Heppner DG et al. A preliminary evaluation of a recombinant circumsporozoite protein vaccine against Plasmodium falciparum malaria. N. Engl. J. Med. 336, 86-91 (1997). RTS,S vaccine protected six out of seven volunteers against experimental challenge with P. falciparum sporozoites, thus indicating progression to field evaluation (see ref. [133]).
    • (1997) N. Engl. J. Med. , vol.336 , pp. 86-91
    • Stoute, J.A.1    Slaoui, M.2    Heppner, D.G.3
  • 133
    • 0035830278 scopus 로고    scopus 로고
    • Efficacy of RTS,S/AS02 malaria vaccine against Plasmodium falciparum infection in semi-immune adult men in The Gambia: A randomised trial
    • Bojang KA, Milligan PJ, Pinder M et al. Efficacy of RTS,S/AS02 malaria vaccine against Plasmodium falciparum infection in semi-immune adult men in The Gambia: a randomised trial. Lancet 358, 1927-1934 (2001). Describes clinical trial of the first pre-erythrocytic vaccine to show significant protection (34% over 15 weeks) against natural P. falciparum.
    • (2001) Lancet , vol.358 , pp. 1927-1934
    • Bojang, K.A.1    Milligan, P.J.2    Pinder, M.3
  • 134
    • 12944255911 scopus 로고    scopus 로고
    • α-galactosylceramide-activated Vα14 natural killer T-cells mediate protection against murine malaria
    • Gonzales-Aseguinolaza G, de Oliveira C, Tomaska M et al. α-galactosylceramide-activated Vα14 natural killer T-cells mediate protection against murine malaria. Proc. Natl Acad. Sci. USA 97, 8461-8466 (2000). See ref. [135].
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 8461-8466
    • Gonzales-Aseguinolaza, G.1    De Oliveira, C.2    Tomaska, M.3
  • 135
    • 0037018103 scopus 로고    scopus 로고
    • Natural killer T-cell ligand α-galactosylceramide enhances protective immunity induced by malaria vaccines
    • Gonzales-Aseguinolaza G, Van Kaer L, Bergmann CC et al. Natural killer T-cell ligand α-galactosylceramide enhances protective immunity induced by malaria vaccines. J. Exp. Med 195, 617-624 (2002). Shows the potential of α-GalCer as an adjuvant capable of enhancing cell-mediated immunity, through the activation of NK-T-cells.
    • (2002) J. Exp. Med. , vol.195 , pp. 617-624
    • Gonzales-Aseguinolaza, G.1    Van Kaer, L.2    Bergmann, C.C.3
  • 136
    • 0028931102 scopus 로고
    • CpG motifs in bacterial DNA trigger direct B-cell activation
    • Krieg AM, Yi AK, Matson S et al. CpG motifs in bacterial DNA trigger direct B-cell activation. Nature 374, 546-549 (1995).
    • (1995) Nature , vol.374 , pp. 546-549
    • Krieg, A.M.1    Yi, A.K.2    Matson, S.3
  • 137
  • 138
    • 0033941792 scopus 로고    scopus 로고
    • Gee whiz: CpG DNA allergy therapy!
    • Askenase PW. Gee whiz: CpG DNA allergy therapy! J. Allergy Clin. Immunol. 106, 37-40 (2000).
    • (2000) J. Allergy Clin. Immunol. , vol.106 , pp. 37-40
    • Askenase, P.W.1
  • 139
    • 0032944291 scopus 로고    scopus 로고
    • Immunostimulatory CpG motifs trigger a T-helper-1 immune response to human immunodeficiency virus type-1 (HIV-1) gp 160 envelope proteins
    • Deml L, Schirmbeck R, Reimann J, Wolf H, Wagner R. Immunostimulatory CpG motifs trigger a T-helper-1 immune response to human immunodeficiency virus type-1 (HIV-1) gp 160 envelope proteins. Clin. Chem. Lab. Med 37, 199-204 (1999).
    • (1999) Clin. Chem. Lab. Med. , vol.37 , pp. 199-204
    • Deml, L.1    Schirmbeck, R.2    Reimann, J.3    Wolf, H.4    Wagner, R.5
  • 140
    • 0032768534 scopus 로고    scopus 로고
    • Immunostimulatory DNA as an adjuvant in vaccination against Leishmania major
    • Stacey KJ, Blackwell JM. Immunostimulatory DNA as an adjuvant in vaccination against Leishmania major. Infect. Immun. 67, 3719-3726 (1999).
    • (1999) Infect. Immun. , vol.67 , pp. 3719-3726
    • Stacey, K.J.1    Blackwell, J.M.2
  • 142
    • 0031569601 scopus 로고    scopus 로고
    • Contribution of CpG motifs to the immunogenicity of DNA vaccines
    • Klinman DM, Yamshchikov G, Ishigatsubo Y. Contribution of CpG motifs to the immunogenicity of DNA vaccines. J. Immunol. 1158, 3635-3639 (1997).
    • (1997) J. Immunol. , vol.1158 , pp. 3635-3639
    • Klinman, D.M.1    Yamshchikov, G.2    Ishigatsubo, Y.3
  • 143
  • 144
    • 0033529512 scopus 로고    scopus 로고
    • Synthetic oligodeoxynucleotides containing CpG motifs enhance immunogenicity of a peptide malaria vaccine in Aotus monkeys
    • Jones TR, Obaldia N III, Gramzinski RA et al. Synthetic oligodeoxynucleotides containing CpG motifs enhance immunogenicity of a peptide malaria vaccine in Aotus monkeys. Vaccine 17, 3065-3071 (1999).
    • (1999) Vaccine , vol.17 , pp. 3065-3071
    • Jones, T.R.1    Obaldia N. III2    Gramzinski, R.A.3
  • 145
    • 0034002814 scopus 로고    scopus 로고
    • Uses of granulocyte-macrophage colony-stimulating factor in vaccine development
    • Warren TL, Weiner GJ. Uses of granulocyte-macrophage colony-stimulating factor in vaccine development. Curr. Opin. Hematol. 7, 168-173 (2000).
    • (2000) Curr. Opin. Hematol. , vol.7 , pp. 168-173
    • Warren, T.L.1    Weiner, G.J.2
  • 146
    • 0032944595 scopus 로고    scopus 로고
    • Co-immunization with DNA vaccines expressing granulocyte-macrophage colony-stimulating factor and mycobacterial secreted proteins enhances T-cell immunity but not protective efficacy against Mycobacterium tuberculosis
    • Kamath AT, Hanke T, Briscoe H, Britton WJ. Co-immunization with DNA vaccines expressing granulocyte-macrophage colony-stimulating factor and mycobacterial secreted proteins enhances T-cell immunity but not protective efficacy against Mycobacterium tuberculosis. Immunology 96, 511-516 (1999).
    • (1999) Immunology , vol.96 , pp. 511-516
    • Kamath, A.T.1    Hanke, T.2    Briscoe, H.3    Britton, W.J.4
  • 147
    • 0031768522 scopus 로고    scopus 로고
    • Enhancement of protective humoral (Th2) and cell-mediated (Th1) immune responses against herpes simplex virus-2 through co-delivery of granulocyte-macrophage colony-stimulating factor expression cassettes
    • Sin JI, Kim JJ, Ugen KE, Ciccarelli RB, Higgins TJ, Weiner DB. Enhancement of protective humoral (Th2) and cell-mediated (Th1) immune responses against herpes simplex virus-2 through co-delivery of granulocyte-macrophage colony-stimulating factor expression cassettes. Eur. J. Immunol. 28, 3530-3540 (1998).
    • (1998) Eur. J. Immunol. , vol.28 , pp. 3530-3540
    • Sin, J.I.1    Kim, J.J.2    Ugen, K.E.3    Ciccarelli, R.B.4    Higgins, T.J.5    Weiner, D.B.6
  • 148
    • 0032754052 scopus 로고    scopus 로고
    • Prevention of neonatal tolerance by a plasmid encoding granulocyte-macrophage colony stimulating factor
    • Ishii KJ, Weiss WR, Klinman DM. Prevention of neonatal tolerance by a plasmid encoding granulocyte-macrophage colony stimulating factor. Vaccine 18, 703-710 (1999).
    • (1999) Vaccine , vol.18 , pp. 703-710
    • Ishii, K.J.1    Weiss, W.R.2    Klinman, D.M.3
  • 149
    • 0031311029 scopus 로고    scopus 로고
    • Granulocyte-macrophage colony-stimulating factor production by T-lymphocytes in Plasmodium berghei-infected mice
    • Owhashi M, Uemura H, Kanbara H, Nawa Y. Granulocyte-macrophage colony-stimulating factor production by T-lymphocytes in Plasmodium berghei-infected mice. Southeast Asian J. Trop. Med. Public Health 28, 757-763 (1997).
    • (1997) Southeast Asian J. Trop. Med. Public Health , vol.28 , pp. 757-763
    • Owhashi, M.1    Uemura, H.2    Kanbara, H.3    Nawa, Y.4
  • 150
    • 0032167401 scopus 로고    scopus 로고
    • A plasmid encoding murine granulocyte-macrophage colony-stimulating factor increases protection conferred by a malaria DNA vaccine
    • Weiss WR, Ishii KJ, Hedstrom RC et al. A plasmid encoding murine granulocyte-macrophage colony-stimulating factor increases protection conferred by a malaria DNA vaccine. J. Immunol. 161, 2325-2332 (1998).
    • (1998) J. Immunol. , vol.161 , pp. 2325-2332
    • Weiss, W.R.1    Ishii, K.J.2    Hedstrom, R.C.3
  • 151
    • 18844463657 scopus 로고    scopus 로고
    • Improving protective immunity induced by DNA-based immunization: Priming with antigen and GM-CSF-encoding plasmid DNA and boosting with antigen-expressing recombinant poxvirus
    • Sedegah M, Weiss W, Sacci JB et al. Improving protective immunity induced by DNA-based immunization: priming with antigen and GM-CSF-encoding plasmid DNA and boosting with antigen-expressing recombinant poxvirus. J. Immunol. 164, 5905-5912 (2000).
    • (2000) J. Immunol. , vol.164 , pp. 5905-5912
    • Sedegah, M.1    Weiss, W.2    Sacci, J.B.3
  • 152
    • 0034939849 scopus 로고    scopus 로고
    • Safety of a GM-CSF adjuvant-plasmid DNA malaria vaccine
    • Parker SE, Monteith D, Horton H et al. Safety of a GM-CSF adjuvant-plasmid DNA malaria vaccine. Gene Ther. 8, 1011-1023 (2001).
    • (2001) Gene Ther. , vol.8 , pp. 1011-1023
    • Parker, S.E.1    Monteith, D.2    Horton, H.3
  • 153
    • 0024580966 scopus 로고
    • Lipopeptide derivatives of bacterial lipoprotein constitute potent immune adjuvants combined with or covalently coupled to antigen or hapten
    • Reitermann A, Metzger J, Wiesmuller KH, Jung G, Bessler WG. Lipopeptide derivatives of bacterial lipoprotein constitute potent immune adjuvants combined with or covalently coupled to antigen or hapten. Biol. Chem. Hoppe Seyler 370, 343-352 (1989).
    • (1989) Biol. Chem. Hoppe Seyler , vol.370 , pp. 343-352
    • Reitermann, A.1    Metzger, J.2    Wiesmuller, K.H.3    Jung, G.4    Bessler, W.G.5
  • 154
    • 0026634780 scopus 로고
    • Synthetic lipopeptides as novel adjuvants
    • Bessler WG, Jung G. Synthetic lipopeptides as novel adjuvants. Res. Immunol. 143, 548-553 (1992).
    • (1992) Res. Immunol. , vol.143 , pp. 548-553
    • Bessler, W.G.1    Jung, G.2
  • 155
    • 0026091287 scopus 로고
    • Efficiency of peptides and lipopeptides for in vivo priming of virus-specific cytotoxic T-cells
    • Schild H, Deres K, Wiesmuller KH, Jung G, Rammensee HG. Efficiency of peptides and lipopeptides for in vivo priming of virus-specific cytotoxic T-cells. Eur. J. Immunol. 21, 2649-2654 (1991).
    • (1991) Eur. J. Immunol. , vol.21 , pp. 2649-2654
    • Schild, H.1    Deres, K.2    Wiesmuller, K.H.3    Jung, G.4    Rammensee, H.G.5
  • 156
    • 0036284382 scopus 로고    scopus 로고
    • Tomatine as an adjuvant in malaria vaccine development
    • Taylor-Robinson AW, Morrow WJW. Tomatine as an adjuvant in malaria vaccine development. Drugs Fut. 27, 391-402 (2002).
    • (2002) Drugs Fut. , vol.27 , pp. 391-402
    • Taylor-Robinson, A.W.1    Morrow, W.J.W.2
  • 158
    • 17344363385 scopus 로고    scopus 로고
    • Phase I/IIa safety, immunogenicity and efficacy trial of NYVAC-Pf7, a pox-vectored, multiantigen, multistage vaccine candidate for Plasmodium falciparum malaria
    • Ockenhouse CF, Sun PF, Lanar DE et al. Phase I/IIa safety, immunogenicity and efficacy trial of NYVAC-Pf7, a pox-vectored, multiantigen, multistage vaccine candidate for Plasmodium falciparum malaria. J. Infect. Dis. 177, 1664-1673 (1998).
    • (1998) J. Infect. Dis. , vol.177 , pp. 1664-1673
    • Ockenhouse, C.F.1    Sun, P.F.2    Lanar, D.E.3
  • 159
    • 0029650205 scopus 로고
    • Identification of conserved antigenic components for a cytotoxic T-lymphocyte-inducing vaccine against malaria
    • Aidoo M, Lalvani A, Allsopp CE et al. Identification of conserved antigenic components for a cytotoxic T-lymphocyte-inducing vaccine against malaria. Lancet 345, 1003-1007 (1995).
    • (1995) Lancet , vol.345 , pp. 1003-1007
    • Aidoo, M.1    Lalvani, A.2    Allsopp, C.E.3
  • 160
    • 0032876566 scopus 로고    scopus 로고
    • Expression and immunogenicity of a liver stage malaria epitope presented as a foreign peptide on the surface of RNA-free MS2 bacteriophage capsids
    • Heal KG, Hill HR, Stockley PG, Hollingdale MR, Taylor-Robinson AW. Expression and immunogenicity of a liver stage malaria epitope presented as a foreign peptide on the surface of RNA-free MS2 bacteriophage capsids. Vaccine 18, 251-258 (1999).
    • (1999) Vaccine , vol.18 , pp. 251-258
    • Heal, K.G.1    Hill, H.R.2    Stockley, P.G.3    Hollingdale, M.R.4    Taylor-Robinson, A.W.5
  • 161
    • 0030012266 scopus 로고    scopus 로고
    • Comparative efficiency of simple lipopeptide constructs for in vivo induction of virus-specific CTL
    • Deprez B, Sauzet JP, Boutillon C et al. Comparative efficiency of simple lipopeptide constructs for in vivo induction of virus-specific CTL. Vaccine 14, 375-382 (1996).
    • (1996) Vaccine , vol.14 , pp. 375-382
    • Deprez, B.1    Sauzet, J.P.2    Boutillon, C.3
  • 162
    • 0030959609 scopus 로고    scopus 로고
    • Lipopeptide immunization without adjuvant induces potent and long-lasting B, T-helper and cytotoxic T-lymphocyte responses against a malaria liver stage antigen in mice and chimpanzees
    • Ben Mohamed L, Gras-Masse H, Tartar A et al. Lipopeptide immunization without adjuvant induces potent and long-lasting B, T-helper and cytotoxic T-lymphocyte responses against a malaria liver stage antigen in mice and chimpanzees. Eur. J. Immunol. 27, 1242-1253 (1997).
    • (1997) Eur. J. Immunol. , vol.27 , pp. 1242-1253
    • Ben Mohamed, L.1    Gras-Masse, H.2    Tartar, A.3
  • 163
    • 0031840826 scopus 로고    scopus 로고
    • Immunogenicity of four Plasmodium falciparum preerythrocytic antigens in Aotus lemurinus monkeys
    • Perlaza BL, Arevalo-Herrera M, Brahimi K et al. Immunogenicity of four Plasmodium falciparum preerythrocytic antigens in Aotus lemurinus monkeys. Infect. Immun. 66, 3423-3428 (1998).
    • (1998) Infect. Immun. , vol.66 , pp. 3423-3428
    • Perlaza, B.L.1    Arevalo-Herrera, M.2    Brahimi, K.3
  • 164
    • 0034659607 scopus 로고    scopus 로고
    • High immunogenicity in chimpanzees of peptides and lipopeptides
    • Ben Mohamad L, Thomas A, Bossus M et al. High immunogenicity in chimpanzees of peptides and lipopeptides derived from four new Plasmodium falciparum pre-erythrocytic molecules. Vaccine 18, 2843-2855 (2000).
    • (2000) Vaccine , vol.18 , pp. 2843-2855
    • Ben Mohamad, L.1    Thomas, A.2    Bossus, M.3
  • 165
    • 0025836774 scopus 로고
    • Fine specificity of cytotoxic T-lymphocytes primed in vivo either with virus or synthetic lipopeptide vaccine or primed in vitro with peptide
    • Schild H, Norda M, Deres K et al. Fine specificity of cytotoxic T-lymphocytes primed in vivo either with virus or synthetic lipopeptide vaccine or primed in vitro with peptide. J. Exp. Med. 174, 1665-1668 (1991).
    • (1991) J. Exp. Med. , vol.174 , pp. 1665-1668
    • Schild, H.1    Norda, M.2    Deres, K.3
  • 166
    • 0028815171 scopus 로고
    • Antigenicity and immunogenicity of recombinant glutamate-rich protein of Plasmodium falciparum expressed in Escherichia coli
    • Theisen M, Vuust J, Gottschau A, Jepsen S, Hogh B. Antigenicity and immunogenicity of recombinant glutamate-rich protein of Plasmodium falciparum expressed in Escherichia coli. Clin. Diagn. Lab. Immunol. 2, 30-34 (1995).
    • (1995) Clin. Diagn. Lab. Immunol. , vol.2 , pp. 30-34
    • Theisen, M.1    Vuust, J.2    Gottschau, A.3    Jepsen, S.4    Hogh, B.5
  • 168
    • 0035949705 scopus 로고    scopus 로고
    • Complete, long-lasting protection against malaria of mice primed and boosted with two distinct viral vectors expressing the same plasmodial antigen
    • Bruna-Romero O, Gonzalez-Aseguinolaza G, Hafalla JC, Tsuji M, Nussenzweig RS. Complete, long-lasting protection against malaria of mice primed and boosted with two distinct viral vectors expressing the same plasmodial antigen. Proc. Natl Acad. Sci. USA 98, 11491-11496 (2001). See ref. [169].
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 11491-11496
    • Bruna-Romero, O.1    Gonzalez-Aseguinolaza, G.2    Hafalla, J.C.3    Tsuji, M.4    Nussenzweig, R.S.5
  • 170
    • 0032560547 scopus 로고    scopus 로고
    • Boosting with recombinant vaccinia increases immunogenicity and protective efficacy of malaria DNA vaccine
    • Sedegah M, Jones TR, Kaur M et al. Boosting with recombinant vaccinia increases immunogenicity and protective efficacy of malaria DNA vaccine. Proc. Natl Acad. Sci. USA 95, 7648-7653 (1998). See ref. [171].
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 7648-7653
    • Sedegah, M.1    Jones, T.R.2    Kaur, M.3
  • 171
    • 0032033577 scopus 로고    scopus 로고
    • Enhancement of MHC class I restricted peptide-specific T-cell induction by a DNA prime/MVA boost vaccination regime
    • Hanke T, Blanchard TJ, Schneider J et al. Enhancement of MHC class I restricted peptide-specific T-cell induction by a DNA prime/MVA boost vaccination regime. Vaccine 16, 439-445 (1998).
    • (1998) Vaccine , vol.16 , pp. 439-445
    • Hanke, T.1    Blanchard, T.J.2    Schneider, J.3
  • 173
    • 0034728778 scopus 로고    scopus 로고
    • Direct immunization of malaria DNA vaccine into the liver by gene gun protects against lethal challenge of Plasmodium berghei sporozoite
    • Yoshida S, Kashiwamura SI, Hosoya Yet al. Direct immunization of malaria DNA vaccine into the liver by gene gun protects against lethal challenge of Plasmodium berghei sporozoite. Biochem. Biophys. Res. Comm. 271, 107-115 (2000).
    • (2000) Biochem. Biophys. Res. Comm. , vol.271 , pp. 107-115
    • Yoshida, S.1    Kashiwamura, S.I.2    Hosoya, Y.3
  • 174
    • 9044243027 scopus 로고    scopus 로고
    • Induction of single and dual cytotoxic T-lymphocyte responses to viral proteins in mice using recombinant hybrid Ty-virus-like particles
    • Layton GT, Harris SJ, Myhan J et al. Induction of single and dual cytotoxic T-lymphocyte responses to viral proteins in mice using recombinant hybrid Ty-virus-like particles. Immunology 87, 171-178 (1996).
    • (1996) Immunology , vol.87 , pp. 171-178
    • Layton, G.T.1    Harris, S.J.2    Myhan, J.3
  • 175
    • 0033005077 scopus 로고    scopus 로고
    • Ty virus-like particles, DNA vaccines and modified vaccinia virus Ankara: Comparisons and combinations
    • Gilbert SC, Schneider J, Plebanski M et al. Ty virus-like particles, DNA vaccines and modified vaccinia virus Ankara: comparisons and combinations. Biol Chem. 380, 299-303 (1999).
    • (1999) Biol Chem. , vol.380 , pp. 299-303
    • Gilbert, S.C.1    Schneider, J.2    Plebanski, M.3
  • 176
    • 14444271599 scopus 로고    scopus 로고
    • Protection from Plasmodium berghei infection by priming and boosting T-cells to a single Class I-restricted epitope with recombinant carriers suitable for human use
    • Plebanski M, Gilbert SC, Schneider J et al. Protection from Plasmodium berghei infection by priming and boosting T-cells to a single Class I-restricted epitope with recombinant carriers suitable for human use. Eur. J. Immunol. 28, 4345-4355 (1998). See ref. [177].
    • (1998) Eur. J. Immunol. , vol.28 , pp. 4345-4355
    • Plebanski, M.1    Gilbert, S.C.2    Schneider, J.3
  • 177
    • 0030713343 scopus 로고    scopus 로고
    • A protein particle vaccine containing multiple malaria epitopes
    • Gilbert SC, Plebanski M, Harris SJ et al. A protein particle vaccine containing multiple malaria epitopes. Nat. Biotechnol. 12, 1280-1284 (1997). Provides a proof-of-concept for using Ty particles expressing plasmodial antigen, then recombinant virus, for prime-boost immunization against pre-erythrocytic malaria.
    • (1997) Nat. Biotechnol. , vol.12 , pp. 1280-1284
    • Gilbert, S.C.1    Plebanski, M.2    Harris, S.J.3
  • 178
    • 0033997173 scopus 로고    scopus 로고
    • + T-cell epitope of the CS protein of P. yoelii enhanced memory response by boosting with recombinant vaccinia virus
    • + T-cell epitope of the CS protein of P. yoelii enhanced memory response by boosting with recombinant vaccinia virus. Vaccine 18, 1863-1869 (2000).
    • (2000) Vaccine , vol.18 , pp. 1863-1869
    • Oliveira-Ferreira, J.1    Miyahira, Y.2    Layton, G.T.3
  • 179
    • 0037081381 scopus 로고    scopus 로고
    • Enhanced CD8 T-cell immunogenicity and protective efficacy in a mouse malaria model using a recombinant adenoviral vaccine in heterologous prime-boost immunisation regimes
    • Gilbert SC, Schneider J, Hannan CM et al. Enhanced CD8 T-cell immunogenicity and protective efficacy in a mouse malaria model using a recombinant adenoviral vaccine in heterologous prime-boost immunisation regimes. Vaccine 20, 1039-1045 (2002).
    • (2002) Vaccine , vol.20 , pp. 1039-1045
    • Gilbert, S.C.1    Schneider, J.2    Hannan, C.M.3


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