Interleukin-10 responses to liver-stage antigen 1 predict human resistance to Plasmodium falciparum

Infection and Immunity

Volumn 67, Issue 7, 1999, Pages 3424-3429

  Kurtis, Jonathan D ^a,c   Lanar, David E ^b   Opollo, Malachi ^a   Duffy, Patrick E ^a,b  

^a KENYA MEDICAL RESEARCH INSTITUTE   (Kenya)

^b WALTER REED ARMY INSTITUTE OF RESEARCH   (United States)

^c HOSPITAL OF THE UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 10; MALARIA VACCINE; PARASITE ANTIGEN; TUMOR NECROSIS FACTOR ALPHA;

ADOLESCENT; ADULT; ARTICLE; CHILD; CONTROLLED STUDY; CYTOKINE PRODUCTION; HUMAN; HUMAN TISSUE; HUMORAL IMMUNITY; IMMUNE RESPONSE; MAJOR CLINICAL STUDY; MALARIA; MALE; PARASITE IMMUNITY; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL;

EID: 0033045397     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/iai.67.7.3424-3429.1999     Document Type: Article

References (36)

1. Aidoo, M., A. Lalvani, C. E. Allsopp, M. Plebanski, S. J. Meisner, P. Krausa, M. Browning, J. S. Morris, F. Gotch, D. A. Fidock, M. Takiguchi, K. J. H. Robson, B. M. Greenwood, P. Druilhe, H. C. Whittle, and A. V. S. Hill. 1995. Identification of conserved antigenic components for a cytotoxic T lymphocyte-inducing vaccine against malaria. Lancet 345:1003-1007.
2. Beier, J. C., C. N. Oster, F. K. Onyango, J. D. Bales, J. A. Sherwood, P. V. Perkins, D. K. Chumo, D. V. Koech, R. E. Whitmire, C. R. Roberts, C. L. Diggs, and S. L. Hoffman. 1994. Plasmodium falciparum incidence relative to entomologic inoculation rates at a site proposed for testing malaria vaccines in western Kenya. Am. J. Trop. Med. Hyg. 50:529-536.
3. Beier, J. C., P. V. Perkins, F. K. Onyango, T. P. Gargan, C. N. Oster, R. E. Whitmire, D. K. Koech, and C. R. Roberts. 1990. Characterization of malaria transmission by Anopheles (Diptera: Culicidae) in western Kenya in preparation for malaria vaccine trials. J. Med. Entomol. 27:570-577.
4. Bouharoun-Tayoun, H., P. Attanath, A. Sabchareon, T. Chongsuphajaisiddhi, and P. Druilhe. 1990. Antibodies that protect humans against Plasmodium falciparum blood stages do not on their own inhibit parasite growth and invasion in vitro, but act in cooperation with monocytes. J. Exp. Med. 172: 1633-1641.
5. Bouharoun-Tayoun, H., C. Oeuvray, F. Lunel, and P. Druilhe. 1995. Mechanisms underlying the monocyte-mediated antibody-dependent killing of Plasmodium falciparum asexual blood stages. J. Exp. Med. 182:409-418.
6. Briere, F., C. Servet-Delprat, J. M. Bridon, J. M. Saint-Remy, and J. Banchereau. 1994. Human interleukin 10 induces naive surface immunoglobulin D+ (sIgD+) B cells to secrete IgG1 and IgG3. J. Exp. Med. 179:757-762.
7. Chen, W. F., and A. Zlotnik. 1991. IL-10: a novel cytotoxic T cell differentiation factor. J. Immunol. 147:528-534.
8. Connelly, M., C. L. King, K. Bucci, S. Walters, B. Genton, M. P. Alpers, M. Hollingdale, and J. W. Kazura. 1997. T-cell immunity to peptide epitopes of liver-stage antigen 1 in an area of Papua New Guinea in which malaria is holoendemic. Infect. Immun. 65:5082-5087.
9. Dieye, A., C. Regier, J. F. Trape, J. L. Sarthou, and P. Druilhe. 1997. HLA class I-associated resistance to severe malaria: a parasitological re-assessment. Parasitol. Today 13:48-49.
10. Doolan, D. L., C. Khamboonruang, H. P. Beck, R. A. Houghten, and M. F. Good. 1993. Cytotoxic T lymphocyte (CTL) low-responsiveness to the Plasmodium falciparum circumsporozoite protein in naturally-exposed endemic populations: analysis of human CTL response to most known variants. Int. Immunol. 5:37-46.
11. Ferreira da Cruz, M. F., D. C. Deslandes, F. J. Oliveira, J. S. Montenegro, A. Tartar, P. Druilhe, and R. C. Daniel. 1995. Antibody responses to Plasmodium falciparum sporozoite-, liver- and blood-stage synthetic peptides in migrant and autochthonous populations in malaria endemic areas. Parasite 2:23-29.
12. Fidock, D. A., H. Gras-Masse, J. P. Lepers, K. Brahimi, L. Benmohamed, S. Mellouk, C. Guerin-Marchand, A. Londono, L. Raharimalala, J. F. Meis, G. Langsley, C. Roussilhon, A. Tartar, and P. Druilhe. 1994. Plasmodium falciparum liver stage antigen-1 is well conserved and contains potent B and T cell determinants. J. Immunol. 153:190-204.
13. Fried, M., R. O. Muga, A. O. Misore, and P. E. Duffy. 1998. Malaria elicits type 1 cytokines in the human placenta: IFN-gamma and TNF-alpha associated with pregnancy outcomes. J. Immunol. 160:2523-2530.
14. Grau, G. E., T. E. Taylor, M. E. Molyneux, J. J. Wirima, P. Vassalli, M. Hommel, and P. H. Lambert. 1989. Tumor necrosis factor and disease severity in children with falciparum malaria. N. Engl. J. Med. 320:1586-1591.
15. Guerin-Marchand, C., P. Druilhe, B. Galey, A. Londono, J. Patarapotikul, R. L. Beaudoin, C. Dubeaux, A. Tartar, O. Mercereau-Puijalon, and G. Langsley. 1987. A liver-stage-specific antigen of Plasmodium falciparum characterized by gene cloning. Nature 329:164-167.
16. Hill, A. V., J. Elvin, A. C. Willis, M. Aidoo, C. E. Allsopp, F. M. Gotch, X. M. Gao, M. Takiguchi, B. M. Greenwood, A. R. Townsend, A. J. McMichael, and H. C. Whittle. 1992. Molecular analysis of the association of HLA-B53 and resistance to severe malaria. Nature 360:434-439.
17. Hollingdale, M. R., M. Aikawa, C. T. Atkinson, W. R. Ballou, G. Chen, J. Li, J. Meis, B. Sina, C. Wright, and J. Zhu. 1990. Non-CS pre-erythrocytic protective antigens. Immunol. Lett. 25:71-76.
18. Jakobsen, P. H., V. McKay, R N'Jie, B. O. Olaleye, U. D'Alessandro, K. Bendtzen, I. Schousboe, and B. M. Greenwood. 1996. Soluble products of inflammatory reactions are not induced in children with asymptomatic Plasmodium falciparum infections. Clin. Exp. Immunol. 105:69-73.
19. Jinquan, T., C. G. Larsen, B. Gesser, K. Matsushima, and K. Thestrup-Pedersen. 1993. Human IL-10 is a chemoattractant for CD8+ T lymphocytes and an inhibitor of IL-8-induced CD4+ T lymphocyte migration. J. Immunol. 151:4545-4551.
20. Kurtis, J. D., and P. E. Duffy. 1997. Unpublished data.
21. Lalani, I., K. Bhol, and A. R. Ahmed. 1997. Interleukin-10: biology, role in inflammation and autoimmunity. Ann. Allergy Asthma Immunol. 79:469-483.
22. Lalvani, A., N. Hurt, M. Aidoo, P. Kibatala, M. Tanner, and A. V. Hill. 1996. Cytotoxic T lymphocytes to Plasmodium falciparum epitopes in an area of intense and perennial transmission in Tanzania. Eur. J. Immunol. 26:773-779.
23. Luty, A. J., J. Mayombo, F. Lekoulou, and R. Mshana. 1994. Immunologic responses to soluble exoantigens of Plasmodium falciparum in Gabonese children exposed to continuous intense infection. Am. J. Trop. Med. Hyg. 51:720-729.
24. Malik, A., J. E. Egan, R. A. Houghten, J. C. Sadoff, and S. L. Hoffman. 1991. Human cytotoxic T lymphocytes against the Plasmodium falciparum circumsporozoite protein. Proc. Natl. Acad. Sci. USA 88:3300-3304.
25. Peyron, F., N. Burdin, P. Ringwald, J. P. Vuillez, F. Rousset, and J. Banchereau. 1994. High levels of circulating IL-10 in human malaria. Clin. Exp. Immunol. 95:300-303.
26. Rodrigues, M. M., A. S. Cordey, G. Arreaza, G. Corradin, P. Romero, J. L. Maryanski, R. S. Nussenzwelg, and F. Zavala. 1991. CD8+ cytolytic T cell clones derived against the Plasmodium yoelii circumsporozoite protein protect against malaria. Int. Immunol. 3:579-585.
27. Rousset, F., E. Garcia, T. Defrance, C. Peronne, N. Vezzio, D. H. Hsu, R. Kastelein, K. W. Moore, and J. Banchereau. 1992. Interleukin 10 is a potent growth and differentiation factor for activated human B lymphocytes. Proc. Natl. Acad. Sci. USA 89:1890-1893.
28. Schofield, L., J. Villaquiran, A. Ferreira, H. Schellekens, R. Nussenzweig, and V. Nussenzweig. 1987. Gamma Interferon, CD8+ T cells and antibodies required for immunity to malaria sporozoites. Nature 330:664-666.
29. te Velde, A., R. Malefijt, R. J. Huijbens, J. de Vries, and C. G. Figdor. 1992 IL-10 stimulates monocyte Fc gamma R surface expression and cytotoxic activity. Distinct regulation of antibody-dependent cellular cytotoxicity by IFN-gamma, IL-4, and IL-10. J. Immunol. 149:4048-4052.
30. van der Poll, T., J. Jansen, M. Levi, H. ten Cate, J. ten Cate, and S. van Deventer. 1994. Regulation of interleukin 10 release by tumor necrosis factor in humans and chimpanzees. J. Exp. Med. 180:185-1988.
31. Wang, R., Y. Charoenvit, G. Corradin, P. De La Vega, E. D. Franke, and S. L. Hoffman. 1996. Protection against malaria by Plasmodium yoelii sporozoite surface protein 2 linear peptide induction of CD4+ T cell- and IFN-gamma-dependent elimination of infected hepatocytes. J. Immunol. 157:4061-4067.
32. Weiss, W. R., S. Mellouk, R. A. Houghten, M. Sedegah, S. Kumar, M. F. Good, J. A. Berzofsky, L. H. Miller, and S. L. Hoffman. 1990. Cytotoxic T cells recognize a peptide from the circumsporozoite protein on malaria-infected hepatocytes. J. Exp. Med. 171:763-773.
33. Wizel, B., R. Houghten, P. Church, J. A. Tine, D. E. Lanar, D. M. Gordon, W. R. Ballou, A. Sette, and S. L. Hoffman. 1995. HLA-A2-restricted cytotoxic T lymphocyte responses to multiple Plasmodium falciparum sporozoite surface protein 2 epitopes in sporozoite-immunized volunteers. J. Immunol. 155:766-775.
34. Wizel, B., R. A. Houghten, K. C. Parker, J. E. Coligan, P. Church, D. M. Gordon, W. R. Ballou, and S. L. Hoffman. 1995. Irradiated sporozoite vaccine induces HLA-B8-restricted cytotoxic T lymphocyte responses against two overlapping epitopes of the Plasmodium falciparum sporozoite surface protein 2. J. Exp. Med. 182:1435-1445.
35. Yang, C., Y. P. Shi, V. Udhayakumar, M. P. Alpers, M. M. Povoa, W. A. Hawley, W. E. Collins, and A. A. Lal. 1995. Sequence variations in the non-repetitive regions of the liver stage-specific antigen-1 (LSA-1) of Plasmodium falciparum from field isolates. Mol. Biochem. Parasitol. 71:291-294.
36. Zhu, J., and M. R. Hollingdale. 1991. Structure of Plasmodium falciparum liver stage antigen-1. Mol. Biochem. Parasitol. 48:223-226.