메뉴 건너뛰기




Volumn 2, Issue 1, 2000, Pages 37-54

Delivery systems for molecular vaccination

Author keywords

Adjuvant; Antigen; Copolymer; Cytokine; Saponin

Indexed keywords

ADJUPHOS; ALUMINUM HYDROXIDE; ALUMINUM SALT; ANTIGEN; BACTERIAL DNA; BIOPOLYMER; CELL WALL SKELETON; COPOLYMER; CRL 1005; CYTOKINE; ENTEROTOXIN; FREUND ADJUVANT; IMMUNOLOGICAL ADJUVANT; ISCOM; ISCOPREP 7.03; L 121; LIPOSOME; MUROCTASIN; N ACETYLMURAMYLALANYL DEXTRO ISOGLUTAMINYLALANYL DIPALMITOYLPHOSPHATIDYLETHANOLAMINE; PHOSPHORYL LIPID A; POLYGLACTIN; PROVAX; QS 21; QUIL A; REHYDRAGEL; SAF; SAPONIN; TITERMAX; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VACCINE; VIRUS VECTOR;

EID: 0034057279     PISSN: 14648431     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (36)

References (162)
  • 1
    • 0003433982 scopus 로고    scopus 로고
    • Harvard University Press
    • Murray CJL, Lopez A (Eds): The Global Burden of Disease and injury. Harvard University Press (1996). A comprehensive report detailing the cost of disease and presenting valid statistical analyses of the socio-economic impact of disease.
    • (1996) The Global Burden of Disease and Injury
    • Murray, C.J.L.1    Lopez, A.2
  • 2
    • 0031966363 scopus 로고    scopus 로고
    • Vaccine visions and their global impact
    • Bloom BR, Widdus R: Vaccine visions and their global impact Nature Med (1998) 4(Suppl 5):480-484.
    • (1998) Nature Med , vol.4 , Issue.SUPPL. 5 , pp. 480-484
    • Bloom, B.R.1    Widdus, R.2
  • 3
    • 0032738026 scopus 로고    scopus 로고
    • Advances in vaccine adjuvants
    • Singh M, O'Hagan D: Advances In vaccine adjuvants. Nature Biotechnol (1999) 17:1075-1081.
    • (1999) Nature Biotechnol , vol.17 , pp. 1075-1081
    • Singh, M.1    O'Hagan, D.2
  • 4
    • 0029785488 scopus 로고    scopus 로고
    • Immunological adjuvants: Mechanisms of action and clinical applications
    • Sheikh N, Rajananthanan P, Morrow WJW: Immunological adjuvants: Mechanisms of action and clinical applications. Exp Opin Invest Drugs (1996) 5:1079-1099.
    • (1996) Exp Opin Invest Drugs , vol.5 , pp. 1079-1099
    • Sheikh, N.1    Rajananthanan, P.2    Morrow, W.J.W.3
  • 5
    • 0029200883 scopus 로고
    • A compendium of vaccine adjuvants and excipients
    • Powell MF, Newman MJ (Eds), Plenum Press
    • Vogel FR, Powell MF: A compendium of vaccine adjuvants and excipients. In: Vaccine Design, the Subunit Approach. Powell MF, Newman MJ (Eds), Plenum Press (1995):141-228. A definitive text detailing different adjuvants, their structures, trade names and their historical development.
    • (1995) Vaccine Design, the Subunit Approach , pp. 141-228
    • Vogel, F.R.1    Powell, M.F.2
  • 6
    • 0025959504 scopus 로고
    • Predicting the absorption of proteins by aluminium-containing adjuvants
    • Seeber SJ, White JL, Hem SL: Predicting the absorption of proteins by aluminium-containing adjuvants. Vaccine (1991) 9:201-203.
    • (1991) Vaccine , vol.9 , pp. 201-203
    • Seeber, S.J.1    White, J.L.2    Hem, S.L.3
  • 7
    • 0025769448 scopus 로고
    • Adverse reactions after injection of adsorbed diphtheria-pertussis-tetanus (DTP) vaccine are not due only to pertussis organisms or pertussis components in the vaccine
    • Gupta RK, Relyveld EH: Adverse reactions after injection of adsorbed diphtheria-pertussis-tetanus (DTP) vaccine are not due only to pertussis organisms or pertussis components In the vaccine. Vaccine (1991) 9:699-702.
    • (1991) Vaccine , vol.9 , pp. 699-702
    • Gupta, R.K.1    Relyveld, E.H.2
  • 8
    • 0029200884 scopus 로고
    • Strucure and properties of aluminium-containing adjuvants
    • Powell MF, Newman MJ (Eds), Plenum Press
    • Hem SL, White JL: Strucure and properties of aluminium-containing adjuvants. In: Vaccine Design, the Subunit Approach. Powell MF, Newman MJ (Eds), Plenum Press (1995):249-276.
    • (1995) Vaccine Design, the Subunit Approach , pp. 249-276
    • Hem, S.L.1    White, J.L.2
  • 9
    • 34047275052 scopus 로고
    • Induction of plasma cell neoplasms in BALB/c strain mice with mineral oil and mineral oil adjuvants
    • Potter M, Boyce CR: Induction of plasma cell neoplasms in BALB/c strain mice with mineral oil and mineral oil adjuvants. Nature (1962) 193:1086-1087. An early report showing the toxic side effects associated with Freund's type adjuvants (see also reference [15]).
    • (1962) Nature , vol.193 , pp. 1086-1087
    • Potter, M.1    Boyce, C.R.2
  • 10
    • 0027180418 scopus 로고
    • Studies of the adjuvant-independent antibody response to immunotargeting. Target structure dependence, Isotype distribution, and induction of long term memory
    • Skea DL, Barber BH: Studies of the adjuvant-independent antibody response to immunotargeting. Target structure dependence, Isotype distribution, and induction of long term memory. J Immunol (1993) 151:3557-3568.
    • (1993) J Immunol , vol.151 , pp. 3557-3568
    • Skea, D.L.1    Barber, B.H.2
  • 12
    • 0023803262 scopus 로고
    • The effect of adjuvants on the efficacy of a recombinant herpes simplex virus glycoprotein vaccine
    • Sanchez-Pescador L, Burke RL, Ott G, Van Nest G: The effect of adjuvants on the efficacy of a recombinant herpes simplex virus glycoprotein vaccine. J Immunol (1988) 141:1720-1727.
    • (1988) J Immunol , vol.141 , pp. 1720-1727
    • Sanchez-Pescador, L.1    Burke, R.L.2    Ott, G.3    Van Nest, G.4
  • 13
    • 0028709479 scopus 로고
    • Targeting of exogenous protein antigens to a novel endosomal processing pathway for class I-restricted presentation
    • Schirmbeck R, Reimann J: Targeting of exogenous protein antigens to a novel endosomal processing pathway for class I-restricted presentation. Behring Inst Mitt (1994) 95:14-22.
    • (1994) Behring Inst Mitt , vol.95 , pp. 14-22
    • Schirmbeck, R.1    Reimann, J.2
  • 14
    • 0001522148 scopus 로고
    • Recommendations for the assessment of adjuvants (Immunopotentiators)
    • Immunological Adjuvants and Vaccines
    • Stewart-Tull DES: Recommendations for the assessment of adjuvants (Immunopotentiators). In: Immunological Adjuvants and Vaccines. NATO ASI Series A: Life Sciences (1988) 179:213-216.
    • (1988) NATO ASI Series A: Life Sciences , vol.179 , pp. 213-216
    • Stewart-Tull, D.E.S.1
  • 15
    • 84961016706 scopus 로고
    • Development of arthritis, periarthritis and periostitis in rats given adjuvant
    • Pearson CM: Development of arthritis, periarthritis and periostitis in rats given adjuvant. Proc Soc Exp Biol Med (1956) 91:95-101. An early report showing the toxic side effects associated with Freund's type adjuvants (see also reference [9]).
    • (1956) Proc Soc Exp Biol Med , vol.91 , pp. 95-101
    • Pearson, C.M.1
  • 16
    • 0015310710 scopus 로고
    • Mineral oil adjuvants: Biological and chemical studies
    • Murray R, Cohen P, Hardegree MC: Mineral oil adjuvants: Biological and chemical studies. Ann Allergy (1972) 30:146-151.
    • (1972) Ann Allergy , vol.30 , pp. 146-151
    • Murray, R.1    Cohen, P.2    Hardegree, M.C.3
  • 17
    • 0000985192 scopus 로고
    • Immunization against neonatal tetanus in toxoid in New Guinea: Antitoxin responses of pregnant women to adjuvant and plain toxolds
    • Maclennan R, Shofield FD, Pittmann M: Immunization against neonatal tetanus in toxoid in New Guinea: Antitoxin responses of pregnant women to adjuvant and plain toxolds. Bull WHO (1965) 32:683-697.
    • (1965) Bull WHO , vol.32 , pp. 683-697
    • Maclennan, R.1    Shofield, F.D.2    Pittmann, M.3
  • 18
    • 0014188189 scopus 로고
    • Preparation and laboratory tests of oil-adjuvant cholera vaccine
    • Ogonuki H, Hashizume S, Takashashi B: Preparation and laboratory tests of oil-adjuvant cholera vaccine. Bull WHO (1967) 37:729-736.
    • (1967) Bull WHO , vol.37 , pp. 729-736
    • Ogonuki, H.1    Hashizume, S.2    Takashashi, B.3
  • 20
    • 0019487639 scopus 로고
    • The adjuvant activity of non-ionic block polymer surfactants I. The role of hydrophlle-lipophile balance
    • Hunter R, Strickland F, Kezdy F: The adjuvant activity of non-ionic block polymer surfactants I. The role of hydrophlle-lipophile balance. J Immunol (1981) 127:1244-1250.
    • (1981) J Immunol , vol.127 , pp. 1244-1250
    • Hunter, R.1    Strickland, F.2    Kezdy, F.3
  • 21
    • 0015326250 scopus 로고
    • Isolation and properties of a macromolecular, water-soluble, immunoadjuvant fraction from the cell wall of Mycobacterium smegmatis
    • Adam A, Clorbaru R, Petit JF, Lederer E: Isolation and properties of a macromolecular, water-soluble, immunoadjuvant fraction from the cell wall of Mycobacterium smegmatis. Proc Natl Acad Sci USA (1972) 69:851-854.
    • (1972) Proc Natl Acad Sci USA , vol.69 , pp. 851-854
    • Adam, A.1    Clorbaru, R.2    Petit, J.F.3    Lederer, E.4
  • 22
    • 0016200846 scopus 로고
    • Minimal structural requirements for adjuvant activity of bacterial peptidoglycan derivatives
    • Ellouz F, Adam A, Ciorbaru R, Lederer A: Minimal structural requirements for adjuvant activity of bacterial peptidoglycan derivatives. Biochem Biophys Res Commun (1974) 59:1317-1325.
    • (1974) Biochem Biophys Res Commun , vol.59 , pp. 1317-1325
    • Ellouz, F.1    Adam, A.2    Ciorbaru, R.3    Lederer, A.4
  • 23
    • 0016800299 scopus 로고
    • Immunoadjuvant activities of synthetic N-acetyl-muramyl-peptides or -amino acids
    • Kotani S, Watanabe Y, Kinoshita F, Shimono T, Morisaki I: Immunoadjuvant activities of synthetic N-acetyl-muramyl-peptides or -amino acids. Biken J (1975) 18:105-111.
    • (1975) Biken J , vol.18 , pp. 105-111
    • Kotani, S.1    Watanabe, Y.2    Kinoshita, F.3    Shimono, T.4    Morisaki, I.5
  • 24
    • 0020051811 scopus 로고
    • The composition of sleep-promoting factor isolated from human urine
    • Krueger JM, Pappenheimer JR, Kamovsky ML: The composition of sleep-promoting factor isolated from human urine. J Biol Chem (1982) 257:1664-1669.
    • (1982) J Biol Chem , vol.257 , pp. 1664-1669
    • Krueger, J.M.1    Pappenheimer, J.R.2    Kamovsky, M.L.3
  • 26
    • 0023730262 scopus 로고
    • Stimulation of non-specific resistance to infection by muroctasin
    • Otani T, Une T, Osada Y: Stimulation of non-specific resistance to infection by muroctasin. Arzneimittelforschung (1988) 38:969-976.
    • (1988) Arzneimittelforschung , vol.38 , pp. 969-976
    • Otani, T.1    Une, T.2    Osada, Y.3
  • 29
    • 0029190258 scopus 로고
    • Development of an emulsion-based muramyl dipeptide adjuvant formulation for vaccines
    • Powell MF, Newman MJ (Eds), Plenum Press
    • Lidgate DM, Byars NE: Development of an emulsion-based muramyl dipeptide adjuvant formulation for vaccines. In: Vaccine design, the Subunit and Adjuvant Approach. Powell MF, Newman MJ (Eds), Plenum Press (1995):313-324.
    • (1995) Vaccine Design, the Subunit and Adjuvant Approach , pp. 313-324
    • Lidgate, D.M.1    Byars, N.E.2
  • 30
    • 0001295075 scopus 로고
    • Studies on the O antigen of Salmonella typhosa. V. Enhancement of antibody responses to protein antigens by the purified polysaccharides
    • Johnson AG, Gains S, Landy M: Studies on the O antigen of Salmonella typhosa. V. Enhancement of antibody responses to protein antigens by the purified polysaccharides. J Exp Med (1956) 103:225-246.
    • (1956) J Exp Med , vol.103 , pp. 225-246
    • Johnson, A.G.1    Gains, S.2    Landy, M.3
  • 31
    • 68949104854 scopus 로고    scopus 로고
    • Adjuvant action of bacterial endotoxins on the primary antibody response
    • Landy M, Braun W (Eds), Rutgers University Press
    • Johnson Ag: Adjuvant action of bacterial endotoxins on the primary antibody response. In: Bacterial Endotoxins. Landy M, Braun W (Eds), Rutgers University Press (1964):252-262.
    • Bacterial Endotoxins , vol.1964 , pp. 252-262
    • Ag, J.1
  • 32
    • 0009367376 scopus 로고
    • Effects of bacteria and bacterial products on antibody response
    • Dixon FJ, Kunkel HG (Eds), Academic Press
    • Munoz J: Effects of bacteria and bacterial products on antibody response. In: Advances in immunology. Dixon FJ, Kunkel HG (Eds), Academic Press (1964):397-404.
    • (1964) Advances in Immunology , pp. 397-404
    • Munoz, J.1
  • 34
    • 0020367633 scopus 로고
    • Purification and structural determination of non-toxic lipid A obtained from the lipopolysaccharide of Salmonella typhimurium
    • Qureshi N, Takayama K, Ribi E: Purification and structural determination of non-toxic lipid A obtained from the lipopolysaccharide of Salmonella typhimurium. J Biol Chem (1982) 257:11808-11815.
    • (1982) J Biol Chem , vol.257 , pp. 11808-11815
    • Qureshi, N.1    Takayama, K.2    Ribi, E.3
  • 35
  • 36
    • 0002689855 scopus 로고
    • Ribi adjuvants: Chemistry, biology and utility in vaccines for human and veterinary medicine
    • Stewart-Tull DES (Ed), J Wiley & Sons
    • Rudbach JA, Johnson DA, Ulrich JT: Ribi adjuvants: Chemistry, biology and utility in vaccines for human and veterinary medicine. In: The Theory and Practical Application of Adjuvants. Stewart-Tull DES (Ed), J Wiley & Sons (1995):287-313.
    • (1995) The Theory and Practical Application of Adjuvants , pp. 287-313
    • Rudbach, J.A.1    Johnson, D.A.2    Ulrich, J.T.3
  • 37
    • 0027183555 scopus 로고
    • Monophosphoryl lipid A enhances specific CTL induction by a soluble protein antigen entrapped in liposomes
    • Zhou F, Huang L: Monophosphoryl lipid A enhances specific CTL induction by a soluble protein antigen entrapped In liposomes. Vaccine (1993) 11:1394-1144. One of the first studies showing that CTL could be induced against soluble protein when formulated with a delivery vehicle.
    • (1993) Vaccine , vol.11 , pp. 1394-11144
    • Zhou, F.1    Huang, L.2
  • 38
    • 0025871167 scopus 로고
    • Differential sensitivity of CD8+ suppressor and cytotoxic T-lymphocyte activity to bacterial monophosphoryl lipid A
    • Esquivel F, Taylor CE, Baker PJ: Differential sensitivity of CD8+ suppressor and cytotoxic T-lymphocyte activity to bacterial monophosphoryl lipid A. Infect Immun (1991) 59:2994-2998.
    • (1991) Infect Immun , vol.59 , pp. 2994-2998
    • Esquivel, F.1    Taylor, C.E.2    Baker, P.J.3
  • 39
    • 0029177836 scopus 로고
    • Liposome design and vaccine development
    • Powell MR, Newman MJ (Eds), Plenum Press
    • Pietrobon PJF: Liposome design and vaccine development In: Vaccine Design, the Subunit Approach. Powell MR, Newman MJ (Eds), Plenum Press (1995):347-361.
    • (1995) Vaccine Design, the Subunit Approach , pp. 347-361
    • Pietrobon, P.J.F.1
  • 40
    • 0016638575 scopus 로고
    • Adjuvant activity of mycobacterial fractions. I Purification of an in vivo adjuvant activity of cell wall skeletons of Mycobacterium bovis BCG, Nocardia asteroides 131 and Corynebacterium diptheriae PWB
    • Azuma I, Kanetsuna F, Taniyama T, Yamamura Y, Hori M: Adjuvant activity of mycobacterial fractions. I Purification of an in vivo adjuvant activity of cell wall skeletons of Mycobacterium bovis BCG, Nocardia asteroides 131 and Corynebacterium diptheriae PWB. Biken J (1975) 18:1-13.
    • (1975) Biken J , vol.18 , pp. 1-13
    • Azuma, I.1    Kanetsuna, F.2    Taniyama, T.3    Yamamura, Y.4    Hori, M.5
  • 41
    • 0017218139 scopus 로고
    • The adjuvant effect of microbial products on the immune response
    • White RG: The adjuvant effect of microbial products on the immune response. Annu Rev Microbiol (1976) 30:579-600.
    • (1976) Annu Rev Microbiol , vol.30 , pp. 579-600
    • White, R.G.1
  • 42
    • 0015694629 scopus 로고
    • The role of anaerobic coryneforms on specific and non-specific immunological reactions. I. Effect of particle clearance and humoral and cell-mediated immunological responses
    • O'Nelll GJ, Henderson DC, White RG: The role of anaerobic coryneforms on specific and non-specific immunological reactions. I. Effect of particle clearance and humoral and cell-mediated immunological responses. Immunology (1973) 24:977-995.
    • (1973) Immunology , vol.24 , pp. 977-995
    • O'Nelll, G.J.1    Henderson, D.C.2    White, R.G.3
  • 44
    • 0002842670 scopus 로고
    • Coploymer Adjuvants and TiterMax ®
    • Stewart-Tull DES (Ed), J Wiley & Sons
    • Hunter RL, Olsen MR, Bennett B. Coploymer Adjuvants and TiterMax ®. In: The Theory and Practical Application of Adjuvants. Stewart-Tull DES (Ed), J Wiley & Sons (1995):51-94. Comprehensive text on the historical development of copolymers, leading to development of TiterMax and other emulsion-based adjuvants.
    • (1995) The Theory and Practical Application of Adjuvants , pp. 51-94
    • Hunter, R.L.1    Olsen, M.R.2    Bennett, B.3
  • 46
    • 0029147797 scopus 로고
    • The induction of cytotoxic T-cells and tumor regression by soluble antigen formulation
    • Hariharan K, Braslawsky G, Black A, Raychaudhuri S, Hanna N: The induction of cytotoxic T-cells and tumor regression by soluble antigen formulation. Cancer Res (1995) 55:3486-3489.
    • (1995) Cancer Res , vol.55 , pp. 3486-3489
    • Hariharan, K.1    Braslawsky, G.2    Black, A.3    Raychaudhuri, S.4    Hanna, N.5
  • 47
    • 0033529479 scopus 로고    scopus 로고
    • Generation of antigen specific CD8+ cytotoxic T-cells following immunization with soluble protein formulated with novel glycoside adjuvants
    • Sheikh NA, Rajananthanan P, Attard GS, Morrow WJW: Generation of antigen specific CD8+ cytotoxic T-cells following immunization with soluble protein formulated with novel glycoside adjuvants. Vaccine (1999) 17:2974-2982.
    • (1999) Vaccine , vol.17 , pp. 2974-2982
    • Sheikh, N.A.1    Rajananthanan, P.2    Attard, G.S.3    Morrow, W.J.W.4
  • 48
    • 0031929959 scopus 로고    scopus 로고
    • Recent advances in immunological adjuvants: The development of paniculate antigen delivery systems
    • O'Hagan DT: Recent advances in immunological adjuvants: The development of paniculate antigen delivery systems. Exp Opin Invest Drugs (1998) 7:349-359. A relatively up-to-date compendia detailing current avaliable particulate adjuvant systems focusing in particular upon Chiron's MF59 adjuvant.
    • (1998) Exp Opin Invest Drugs , vol.7 , pp. 349-359
    • O'Hagan, D.T.1
  • 49
    • 0028792511 scopus 로고
    • Enhancement of humoral response against human influenza vaccine with the simple submicron oil/water emulsion adjuvant MF59
    • Ott G, Barchfeld GL, Van Nest G: Enhancement of humoral response against human influenza vaccine with the simple submicron oil/water emulsion adjuvant MF59. Vaccine (1995) 13:1557-1562.
    • (1995) Vaccine , vol.13 , pp. 1557-1562
    • Ott, G.1    Barchfeld, G.L.2    Van Nest, G.3
  • 51
    • 0027326731 scopus 로고
    • Pilot evaluation of influenza virus vaccine (IVV) combined with adjuvant
    • Keitel W, Couch R, Bond N, Adair S, Van Nest G, Dekker C: Pilot evaluation of influenza virus vaccine (IVV) combined with adjuvant. Vaccine (1993) 11:909-913.
    • (1993) Vaccine , vol.11 , pp. 909-913
    • Keitel, W.1    Couch, R.2    Bond, N.3    Adair, S.4    Van Nest, G.5    Dekker, C.6
  • 52
    • 0031917995 scopus 로고    scopus 로고
    • Intranasal Immunization of mice with herpes simplex virus type 2 recombinant gD2: The effect of adjuvants on mucosal and
    • Ugozzoli M, O'Hagan DT, Ott GS: Intranasal Immunization of mice with herpes simplex virus type 2 recombinant gD2: The effect of adjuvants on mucosal and serum antibody responses. Immunology (1998) 93:563-571.
    • (1998) Immunology , vol.93 , pp. 563-571
    • Ugozzoli, M.1    O'Hagan, D.T.2    Ott, G.S.3    Responses, S.A.4
  • 55
    • 0027988552 scopus 로고
    • Clinical and immunologie responses to human immunodeficiency virus (HIV) type 1SF2 gp120 subunit vaccine combined with MF59 adjuvant with or without muramyl tripeptide dipalmitoyl phosphatidylethanolamine in non-HIV-infected human volunteers
    • Kahn JO, Sinangil F, Baenziger J, Murcar N, Wynne D, Coleman RL, Steimer KS, Dekker CL, Chemoff D: Clinical and immunologie responses to human immunodeficiency virus (HIV) type 1SF2 gp120 subunit vaccine combined with MF59 adjuvant with or without muramyl tripeptide dipalmitoyl phosphatidylethanolamine in non-HIV-infected human volunteers. J Infect Dis (1994) 170:1288-1291.
    • (1994) J Infect Dis , vol.170 , pp. 1288-1291
    • Kahn, J.O.1    Sinangil, F.2    Baenziger, J.3    Murcar, N.4    Wynne, D.5    Coleman, R.L.6    Steimer, K.S.7    Dekker, C.L.8    Chemoff, D.9
  • 56
    • 0029000226 scopus 로고
    • A recombinant glycoprotein vaccine for herpes simplex virus type 2: Safety and immunogenicity
    • Langenberg AGM, Burke RL, Adair SF, Sekulovich R, Tigges M, Dekker CL, Corey L: A recombinant glycoprotein vaccine for herpes simplex virus type 2: Safety and immunogenicity. Ann Intern Med (1995) 122:889-898.
    • (1995) Ann Intern Med , vol.122 , pp. 889-898
    • Agm, L.1    Burke, R.L.2    Adair, S.F.3    Sekulovich, R.4    Tigges, M.5    Dekker, C.L.6    Corey, L.7
  • 57
    • 0029177785 scopus 로고
    • Development of vaccines based on formulations containing non-ionic block copolymers
    • Powell MF, Newman MJ (Eds), Plenum Press
    • Brey RN: Development of vaccines based on formulations containing non-ionic block copolymers. In: Vaccine Design, the Subunit and Adjuvant Approach. Powell MF, Newman MJ (Eds), Plenum Press (1995):297-311.
    • (1995) Vaccine Design, the Subunit and Adjuvant Approach , pp. 297-311
    • Brey, R.N.1
  • 58
    • 0031569334 scopus 로고    scopus 로고
    • Non-ionic triblock copolymers facilitate delivery of exogenous proteins into the MHC class I and class II processing pathways
    • Ke Y, McGraw CL, Hunter RL, Kapp JA: Non-ionic triblock copolymers facilitate delivery of exogenous proteins Into the MHC class I and class II processing pathways. Cell Immunol (1997) 176:113-121.
    • (1997) Cell Immunol , vol.176 , pp. 113-121
    • Ke, Y.1    McGraw, C.L.2    Hunter, R.L.3    Kapp, J.A.4
  • 59
    • 0015872838 scopus 로고
    • Chemical and biological basis of adjuvants
    • Kleinzeller A, Springer G, Wittmann H (Eds), Springer-Verlag
    • Jolies P, Paraf A: Chemical and biological basis of adjuvants. In: Molecular Biology and Biochemistry and Biophysics. Kleinzeller A, Springer G, Wittmann H (Eds), Springer-Verlag (1973):1-153.
    • (1973) Molecular Biology and Biochemistry and Biophysics , pp. 1-153
    • Jolies, P.1    Paraf, A.2
  • 60
    • 1642610331 scopus 로고
    • Biological properties of lipotelchoic acids
    • Schlessinger D (Ed), American Society Microbiology
    • Wicken A, Knox K: Biological properties of lipotelchoic acids. In: Microbiology. Schlessinger D (Ed), American Society Microbiology (1977):131-154.
    • (1977) Microbiology , pp. 131-154
    • Wicken, A.1    Knox, K.2
  • 61
    • 36048950697 scopus 로고
    • A review of block polymer surfactants
    • Schmoika IR: A review of block polymer surfactants. J Am Oil Chem Soc (1977) 54:110-116.
    • (1977) J Am Oil Chem Soc , vol.54 , pp. 110-116
    • Schmoika, I.R.1
  • 62
    • 0021676387 scopus 로고    scopus 로고
    • The adjuvant activity of nonionic block polymer surfactants. II. Antibody formation and inflammation related to the structure of triblock and octabloack copolymers
    • Hunter RL, Bennett B: The adjuvant activity of nonionic block polymer surfactants. II. Antibody formation and inflammation related to the structure of triblock and octabloack copolymers. J Immunol (1998) 133:3167-3175.
    • (1998) J Immunol , vol.133 , pp. 3167-3175
    • Hunter, R.L.1    Bennett, B.2
  • 63
    • 85012373035 scopus 로고
    • Diffusion of univalent ions across the lamellae of swollen phospholipids
    • Bangham AD, Standish MM, Watkins JC: Diffusion of univalent ions across the lamellae of swollen phospholipids. J Mol Biol (1965) 13:238-252.
    • (1965) J Mol Biol , vol.13 , pp. 238-252
    • Bangham, A.D.1    Standish, M.M.2    Watkins, J.C.3
  • 64
    • 0014360953 scopus 로고
    • Membrane models with phospholipids
    • Bangham AD: Membrane models with phospholipids. Prog Biophys Mol Biol (1968) 18:29-95.
    • (1968) Prog Biophys Mol Biol , vol.18 , pp. 29-95
    • Bangham, A.D.1
  • 65
    • 0002467273 scopus 로고
    • Enzyme entrapment in liposomes
    • Gregoriadis G, Leathwood PD: Enzyme entrapment in liposomes. FEBS Lett (1971) 14:95-99. One of the proposals for lipsome entrapment of protein.
    • (1971) FEBS Lett , vol.14 , pp. 95-99
    • Gregoriadis, G.1    Leathwood, P.D.2
  • 66
    • 0016309080 scopus 로고
    • Incorporation of lipid vesicles by mammalian cells provides a potential method for modifying cell behaviour
    • Papahadjopoulos D, Mayhew E, Poste G, Smith S, Vail WJ: Incorporation of lipid vesicles by mammalian cells provides a potential method for modifying cell behaviour. Nature (1974) 252:163-166.
    • (1974) Nature , vol.252 , pp. 163-166
    • Papahadjopoulos, D.1    Mayhew, E.2    Poste, G.3    Smith, S.4    Vail, W.J.5
  • 67
    • 0002121838 scopus 로고    scopus 로고
    • Stealth liposome technology: An overview
    • Martin FJ: Stealth liposome technology: An overview. Doxil Clinical Series (1996) 1:1-8.
    • (1996) Doxil Clinical Series , vol.1 , pp. 1-8
    • Martin, F.J.1
  • 68
    • 0025996054 scopus 로고
    • Liposome-encapsulated antigens engender lysosomal processing for class II MHC presentation and cytosolic processing for class I presentation
    • Harding CV, Collins DS, Kanagawa O, Unanue ER: Liposome-encapsulated antigens engender lysosomal processing for class II MHC presentation and cytosolic processing for class I presentation. J Immunol (1991) 147:2860-2863.
    • (1991) J Immunol , vol.147 , pp. 2860-2863
    • Harding, C.V.1    Collins, D.S.2    Kanagawa, O.3    Unanue, E.R.4
  • 69
    • 0026713158 scopus 로고
    • Class I restricted CTL recognition of a soluble protein delivered by liposomes containing lipophillc polylysines
    • Nair S, Zhou X, Huang L, Rouse BT: Class I restricted CTL recognition of a soluble protein delivered by liposomes containing lipophillc polylysines. J Immunol Methods (1992) 152:237-243. An early work by this group showing that CTL could be induced against soluble protein, the authors hypothesized that alternative antigen-processing pathways to the conventionally accepted cytosolic-baced pathways could be responsible for this nonconventional CTL generation. Further studies by the authors have shown their original premise to be true using in vitro systems.
    • (1992) J Immunol Methods , vol.152 , pp. 237-243
    • Nair, S.1    Zhou, X.2    Huang, L.3    Rouse, B.T.4
  • 70
    • 0027462372 scopus 로고
    • Electroporation and commercial liposomes efficiently deliver soluble protein into the MHC class I presentation pathway. Priming in vitro and in vivo for class I-restricted recognition of soluble antigen
    • Chen W, Carbone FR, McCluskey J: Electroporation and commercial liposomes efficiently deliver soluble protein Into the MHC class I presentation pathway. Priming in vitro and in vivo for class I-restricted recognition of soluble antigen. J Immunol Methods (1993) 160:49-57.
    • (1993) J Immunol Methods , vol.160 , pp. 49-57
    • Chen, W.1    Carbone, F.R.2    McCluskey, J.3
  • 71
    • 0033529590 scopus 로고    scopus 로고
    • Cytotoxic T-lymphocytes to Ebola Zaire virus are induced in mice by immunizing with liposomes containing lipid A
    • Rao M, matyas GR, Grieder F, Andersen K, Jahrling PB, Alving CR: Cytotoxic T-lymphocytes to Ebola Zaire virus are induced in mice by immunizing with liposomes containing lipid A. Vaccine (1999) 17:2991-2998.
    • (1999) Vaccine , vol.17 , pp. 2991-2998
    • Rao, M.1    Matyas, G.R.2    Grieder, F.3    Andersen, K.4    Jahrling, P.B.5    Alving, C.R.6
  • 72
    • 0028099634 scopus 로고
    • Liposome-mediated cytoplasmic delivery of proteins: An effective means of accessing the MHC class I-restricted antigen presentation pathway
    • Zhou F, Huang L: Liposome-mediated cytoplasmic delivery of proteins: An effective means of accessing the MHC class I-restricted antigen presentation pathway. Immunomethods (1994) 4:229-235.
    • (1994) Immunomethods , vol.4 , pp. 229-235
    • Zhou, F.1    Huang, L.2
  • 73
    • 49049150053 scopus 로고
    • Saponins in food: A review
    • Oakenfull D: Saponins in food: A review. Food Chem (1981) 6:19-40.
    • (1981) Food Chem , vol.6 , pp. 19-40
    • Oakenfull, D.1
  • 74
    • 0023064090 scopus 로고
    • The chemistry and biological significance of saponins in foods and feedingstuffs
    • Price KR, Johnson IT, Fenwick GR: The chemistry and biological significance of saponins in foods and feedingstuffs. Crit Rev Food Sci Nutr (1987) 26:127-135.
    • (1987) Crit Rev Food Sci Nutr , vol.26 , pp. 127-135
    • Price, K.R.1    Johnson, I.T.2    Fenwick, G.R.3
  • 75
    • 0022555408 scopus 로고
    • Marine pharmacology: Bioactive molecules from the sea
    • Kaul PN, Daftari P: Marine pharmacology: Bioactive molecules from the sea. Annu Rev Pharmacol Toxicol (1986) 26:117-142.
    • (1986) Annu Rev Pharmacol Toxicol , vol.26 , pp. 117-142
    • Kaul, P.N.1    Daftari, P.2
  • 76
    • 0343514147 scopus 로고
    • Nouveau vaccin antiaphteux a complexe glucoviral
    • Espinet RG: Nouveau vaccin antiaphteux a complexe glucoviral. Gac Vet (1951) 13:268-270.
    • (1951) Gac Vet , vol.13 , pp. 268-270
    • Espinet, R.G.1
  • 77
    • 0014487050 scopus 로고
    • The influence of aluminium hydroxide content, dose volume and the inclusion of saponln on the efficacy of inactivated foot-and-mouth disease vaccines
    • Hyslop NSG, Morrow AW: The influence of aluminium hydroxide content, dose volume and the inclusion of saponln on the efficacy of inactivated foot-and-mouth disease vaccines. Res Vet Sci (1969) 10:109-120. Early report describing the adjuvant efffect of saponin.
    • (1969) Res Vet Sci , vol.10 , pp. 109-120
    • Nsg, H.1    Morrow, A.W.2
  • 78
    • 0014905993 scopus 로고
    • Thin layer chromatography fingerprinting of commercially available saponins
    • Dalsgard K: Thin layer chromatography fingerprinting of commercially available saponins. Dan Tidsskr Farm (1970) 44:337-331.
    • (1970) Dan Tidsskr Farm , vol.44 , pp. 337-1331
    • Dalsgard, K.1
  • 82
    • 0028158885 scopus 로고
    • Vaccination with immunodomlnant peptides encapsulated in Quil A-containing liposomes induces peptide-specific primary CD8+ cytotoxic T-cells
    • Lipford GB, Wagner H, Heeg K: Vaccination with immunodomlnant peptides encapsulated In Quil A-containing liposomes induces peptide-specific primary CD8+ cytotoxic T-cells. Vaccine (1994) 12:73-80.
    • (1994) Vaccine , vol.12 , pp. 73-80
    • Lipford, G.B.1    Wagner, H.2    Heeg, K.3
  • 84
    • 0031171898 scopus 로고    scopus 로고
    • Induction of cross-reactive cytotoxic T-lymphocyte responses specific for HIV-1 gp120 using saponin adjuvant (QS-21) supplemented subunit vaccine formulations
    • Newman MJ, Wu JY, Gardner BH, Anderson CA, Kensil CR, Recchia J, Coughlin RT, Powell MF: Induction of cross-reactive cytotoxic T-lymphocyte responses specific for HIV-1 gp120 using saponin adjuvant (QS-21) supplemented subunit vaccine formulations. Vaccine (1997) 15:1001-1007.
    • (1997) Vaccine , vol.15 , pp. 1001-1007
    • Newman, M.J.1    Wu, J.Y.2    Gardner, B.H.3    Anderson, C.A.4    Kensil, C.R.5    Recchia, J.6    Coughlin, R.T.7    Powell, M.F.8
  • 85
    • 0031626756 scopus 로고    scopus 로고
    • QS-21 and QS-7: Purified saponin adjuvants
    • Kensil CR, Wu JY, Anderson CA, Wheeler DA, Amsden J: QS-21 and QS-7: Purified saponin adjuvants. Dev Biol Stand (1998) 92:41-47. Comprehensive review illustrating the use of two of the most widely used saponin derivatives as adjuvants.
    • (1998) Dev Biol Stand , vol.92 , pp. 41-47
    • Kensil, C.R.1    Wu, J.Y.2    Anderson, C.A.3    Wheeler, D.A.4    Amsden, J.5
  • 87
    • 0018819611 scopus 로고
    • Saponin and other haemolysins (vitamin A, aliphatic amines, polyene antibiotics) as adjuvants for SRBC in the mouse. Evidence for a role for cholesterol-binding in saponin adjuvanticity
    • Bomford R: Saponin and other haemolysins (vitamin A, aliphatic amines, polyene antibiotics) as adjuvants for SRBC In the mouse. Evidence for a role for cholesterol-binding in saponin adjuvanticity. Int Arch Allergy Appl Immunol (1980) 63:170-177.
    • (1980) Int Arch Allergy Appl Immunol , vol.63 , pp. 170-177
    • Bomford, R.1
  • 88
    • 0025005020 scopus 로고
    • The ISCOM: An Immuonstimulating system
    • Morein B: The ISCOM: An Immuonstimulating system. Immunol Lett (1990) 25:281-283. A simple description of the potentials of ISCOM use for vaccination.
    • (1990) Immunol Lett , vol.25 , pp. 281-283
    • Morein, B.1
  • 89
    • 0025762026 scopus 로고
    • Vaccination of class I major histocompatibllity complex (MHC)-restricted murine CD8+ cytotoxic T-lymphocytes towards soluble antigens: Immunostimulating-ovalbumin complexes enter the class I MHC-antigen pathway and allow sensitization against the immunodominant peptide
    • Heeg K, Kuon W, Wagner H: Vaccination of class I major histocompatibllity complex (MHC)-restricted murine CD8+ cytotoxic T-lymphocytes towards soluble antigens: Immunostimulating-ovalbumin complexes enter the class I MHC-antigen pathway and allow sensitization against the immunodominant peptide. Eur J Immunol (1991) 21:1523-1527.
    • (1991) Eur J Immunol , vol.21 , pp. 1523-1527
    • Heeg, K.1    Kuon, W.2    Wagner, H.3
  • 90
    • 0025998909 scopus 로고
    • ISCOMS - A novel strategy for mucosal immunizations?
    • Mowatt AM, Donachie AM: ISCOMS - a novel strategy for mucosal immunizations? Immunol Today (1991) 12:383-385.
    • (1991) Immunol Today , vol.12 , pp. 383-385
    • Mowatt, A.M.1    Donachie, A.M.2
  • 91
    • 0030581353 scopus 로고    scopus 로고
    • Linkage of a fusion peptide to a CTL epitope from the nucleoprotein of measles virus enables incorporation into ISCOMs and induction of CTL responses following intranasal immunization
    • Hsu SC, Schadeck EB, Delmas A, Shaw M, Steward MW: Linkage of a fusion peptide to a CTL epitope from the nucleoprotein of measles virus enables incorporation into ISCOMs and induction of CTL responses following intranasal immunization. Vaccine (1996) 14:1159-1166.
    • (1996) Vaccine , vol.14 , pp. 1159-1166
    • Hsu, S.C.1    Schadeck, E.B.2    Delmas, A.3    Shaw, M.4    Steward, M.W.5
  • 93
    • 0032502592 scopus 로고    scopus 로고
    • Internalization of ISCOM-borne antigens and presentation under MHC-Class I or class II restriction
    • Villacres MC, Behboudi S, Nikkila T, Lovgren-Bengtsson K, Morein B: Internalization of ISCOM-borne antigens and presentation under MHC-Class I or class II restriction. Cell Immunol (1997) 185:30-38. A finely constructed study showing ISCOM affect upon enhancing both humoral and cell-mediated immune responses. Additionally, the authors showed ISCOM localization within various cellular agtigen-processing compartments leading to the conclusion that ISCOMs did not target particular agtigen processing pathways but acted in a non-specific manner, delivering their load to many different cellular compartments.
    • (1997) Cell Immunol , vol.185 , pp. 30-38
    • Villacres, M.C.1    Behboudi, S.2    Nikkila, T.3    Lovgren-Bengtsson, K.4    Morein, B.5
  • 97
    • 0033605353 scopus 로고    scopus 로고
    • Evaluation of novel aggregate structures as adjuvants: Composition, toxicity studies and humoral responses
    • Rajananthanan P, Attard GS, Sheikh NA, Morrow WJW: Evaluation of novel aggregate structures as adjuvants: Composition, toxicity studies and humoral responses. Vaccine (1999) 17:715-730.
    • (1999) Vaccine , vol.17 , pp. 715-730
    • Rajananthanan, P.1    Attard, G.S.2    Sheikh, N.A.3    Morrow, W.J.W.4
  • 100
    • 0028307848 scopus 로고
    • Microsphere absorption by the nasal mucosa of the rat
    • Alpar HO, Almeida AJ, Brown MRW: Microsphere absorption by the nasal mucosa of the rat J Drug Targeting (1994) 2:147-149.
    • (1994) J Drug Targeting , vol.2 , pp. 147-149
    • Alpar, H.O.1    Almeida, A.J.2    Brown, M.R.W.3
  • 101
    • 0031251876 scopus 로고    scopus 로고
    • The Immunotargeting approach to adjuvant-independent subunlt vaccine design
    • Barber BH: The Immunotargeting approach to adjuvant-independent subunlt vaccine design. Semin Immunol (1997) 9:293-301.
    • (1997) Semin Immunol , vol.9 , pp. 293-301
    • Barber, B.H.1
  • 102
    • 0022638799 scopus 로고
    • Enhancement of antigenic potency in vitro and immunogenicity in vivo by coupling the antigen to anti-immunoglobulin
    • Kawamura H, Berzofsky JA: Enhancement of antigenic potency in vitro and immunogenicity in vivo by coupling the antigen to anti-immunoglobulin. J Immunol (1986) 136:58-65.
    • (1986) J Immunol , vol.136 , pp. 58-65
    • Kawamura, H.1    Berzofsky, J.A.2
  • 104
    • 0026785269 scopus 로고
    • Synthetic peptides as vaccines
    • Arnon R, Horwitz RJ: Synthetic peptides as vaccines. Curr Opin Immunol (1992) 4:449-453.
    • (1992) Curr Opin Immunol , vol.4 , pp. 449-453
    • Arnon, R.1    Horwitz, R.J.2
  • 106
    • 0030048724 scopus 로고    scopus 로고
    • Peptide-pulsed dendritic cells induce antigen-specific CTL-mediated protective tumor immunity
    • Celluzzi CM, Mayordomo JI, Storkus WJ, Lotze MT, Falo LD: Peptide-pulsed dendritic cells induce antigen-specific CTL-mediated protective tumor immunity. J Exp Med (1996) 183:283-287.
    • (1996) J Exp Med , vol.183 , pp. 283-287
    • Celluzzi, C.M.1    Mayordomo, J.I.2    Storkus, W.J.3    Lotze, M.T.4    Falo, L.D.5
  • 107
    • 0033120074 scopus 로고    scopus 로고
    • Therapy of murine tumors with recombinant Bordetella pertussis adenylate cyclase carrying a cytotoxic T-cell epitope
    • Fayolle C, Ladant D, Karimova G, Ullmann A, Leclerc C: Therapy of murine tumors with recombinant Bordetella pertussis adenylate cyclase carrying a cytotoxic T-cell epitope. J Immunol (1999) 162:4157-4162. One in a series of many studies by this group showing how antigen can be delivered directly into the class I processing pathway using bacterial membrane insertion vector technology.
    • (1999) J Immunol , vol.162 , pp. 4157-4162
    • Fayolle, C.1    Ladant, D.2    Karimova, G.3    Ullmann, A.4    Leclerc, C.5
  • 108
    • 0032514638 scopus 로고    scopus 로고
    • Charge-dependent translocation of Bordetella pertussis adenylate cyclase toxin into eukaryotic cells: Implication for the in vivo delivery of CD8(+) T-cell epitopes into antigen-presenting cells
    • Karimova G, Fayolle C, Ullmann A, Leclerc C, Ladant D: Charge-dependent translocation of Bordetella pertussis adenylate cyclase toxin into eukaryotic cells: Implication for the in vivo delivery of CD8(+) T-cell epitopes into antigen-presenting cells. Proc Natl Acad Sci USA (1998) 95:12532-12537.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 12532-12537
    • Karimova, G.1    Fayolle, C.2    Ullmann, A.3    Leclerc, C.4    Ladant, D.5
  • 109
    • 0026574666 scopus 로고
    • Distinct steps in the penetration of adenylate cyclase toxin of Bordetella pertussis into sheep erythrocytes. Translocation of the toxin across the membrane
    • Rogel A, Hanski E: Distinct steps in the penetration of adenylate cyclase toxin of Bordetella pertussis into sheep erythrocytes. Translocation of the toxin across the membrane. J Biol Chem (1992) 267:22599-22605.
    • (1992) J Biol Chem , vol.267 , pp. 22599-22605
    • Rogel, A.1    Hanski, E.2
  • 110
    • 0024449602 scopus 로고
    • Bordetella pertussis adenylate cyclase: Purification and characterization of the toxic form of the enzyme
    • Rogel A, Schultz JE, Brownlie RM, Coote JG, Parton R, Hanski E: Bordetella pertussis adenylate cyclase: Purification and characterization of the toxic form of the enzyme. EMBO J (1989) 8:2755-2760.
    • (1989) EMBO J , vol.8 , pp. 2755-2760
    • Rogel, A.1    Schultz, J.E.2    Brownlie, R.M.3    Coote, J.G.4    Parton, R.5    Hanski, E.6
  • 111
    • 0022262657 scopus 로고
    • Bordetella pertussis invasive adenylate cyclase. Partial resolution and properties of its cellular penetration
    • Hanski E, Fartel Z: Bordetella pertussis invasive adenylate cyclase. Partial resolution and properties of its cellular penetration. J Biol Chem (1985) 260:5526-5532.
    • (1985) J Biol Chem , vol.260 , pp. 5526-5532
    • Hanski, E.1    Fartel, Z.2
  • 112
    • 0028941589 scopus 로고
    • Membrane depolarization prevents cell invasion by Bordetella pertussis adenylate cyclase toxin
    • Otero AS, Yi XB, Gray MC, Szabo G, Hewlett EL: Membrane depolarization prevents cell invasion by Bordetella pertussis adenylate cyclase toxin. J Biol Chem (1995) 270:9695-9697.
    • (1995) J Biol Chem , vol.270 , pp. 9695-9697
    • Otero, A.S.1    Yi, X.B.2    Gray, M.C.3    Szabo, G.4    Hewlett, E.L.5
  • 115
    • 0030992213 scopus 로고    scopus 로고
    • Induction of neutralizing antibody and T-cell responses to varicella-zoster virus (VZV) using Ty-virus-like particles carrying fragments of glycoproteln E (gE)
    • Garcia-Valcarcel M, Fowler WJ, Harper DR, Jeffries DJ, Layton GT: Induction of neutralizing antibody and T-cell responses to varicella-zoster virus (VZV) using Ty-virus-like particles carrying fragments of glycoproteln E (gE). Vaccine (1997) 15:709-719.
    • (1997) Vaccine , vol.15 , pp. 709-719
    • Garcia-Valcarcel, M.1    Fowler, W.J.2    Harper, D.R.3    Jeffries, D.J.4    Layton, G.T.5
  • 117
    • 0032839902 scopus 로고    scopus 로고
    • A recombinant human papillomavirus (HPV) type 16 L1-vaccinia virus murine challenge model demonstrates cell-mediated immunity against HPV virus-like particles
    • Marals D, Passmore JA, Maclean J, Rose R, Williamson AL: A recombinant human papillomavirus (HPV) type 16 L1-vaccinia virus murine challenge model demonstrates cell-mediated immunity against HPV virus-like particles. J Gen Virol (1999) 80:2471-2475.
    • (1999) J Gen Virol , vol.80 , pp. 2471-2475
    • Marals, D.1    Passmore, J.A.2    Maclean, J.3    Rose, R.4    Williamson, A.L.5
  • 118
    • 0032722995 scopus 로고    scopus 로고
    • Nucleic acid Immunization: Concepts and techniques associated with third generation vaccines
    • Hasan UA, Abal AM, Harper DR, Wren BW, Morrow WJW: Nucleic acid Immunization: Concepts and techniques associated with third generation vaccines. J Immunol Methods (1999) 229:1-22.
    • (1999) J Immunol Methods , vol.229 , pp. 1-22
    • Hasan, U.A.1    Abal, A.M.2    Harper, D.R.3    Wren, B.W.4    Morrow, W.J.W.5
  • 119
    • 0029878034 scopus 로고    scopus 로고
    • Induction of cytotoxic T-lymphocytes and antitumor immunity with DNA vaccines expressing single T-cell epitopes
    • Ciernik IF, Berzofsky JA, Carbone DP: Induction of cytotoxic T-lymphocytes and antitumor immunity with DNA vaccines expressing single T-cell epitopes. J Immunol (1996) 156:2369-2375.
    • (1996) J Immunol , vol.156 , pp. 2369-2375
    • Ciernik, I.F.1    Berzofsky, J.A.2    Carbone, D.P.3
  • 123
    • 0033215423 scopus 로고    scopus 로고
    • Oligodeoxynucleotides containing palindrome sequences with internal 5′-CpG-3′ act directly on human NK and activated T-cells to induce IFN-γ production in vitro
    • Iho S, Yamamoto T, Takahashi T, Yamamoto S: Oligodeoxynucleotides containing palindrome sequences with internal 5′-CpG-3′ act directly on human NK and activated T-cells to induce IFN-γ production in vitro. J Immunol (1999) 163:3642-3652.
    • (1999) J Immunol , vol.163 , pp. 3642-3652
    • Iho, S.1    Yamamoto, T.2    Takahashi, T.3    Yamamoto, S.4
  • 124
    • 0031964257 scopus 로고    scopus 로고
    • CpG DNA is a potent enhancer of specific immunity in mice immunized with recombinant hepatitis B surface antigen
    • Davis HL, Weeratna R, Waldschmidt TJ, Tygrett L, Schorr J, Krieg AM: CpG DNA is a potent enhancer of specific immunity in mice immunized with recombinant hepatitis B surface antigen. J Immunol (1998) 160:870-876.
    • (1998) J Immunol , vol.160 , pp. 870-876
    • Davis, H.L.1    Weeratna, R.2    Waldschmidt, T.J.3    Tygrett, L.4    Schorr, J.5    Krieg, A.M.6
  • 125
    • 0030175501 scopus 로고    scopus 로고
    • Mechanisms of antigen uptake for presentation
    • Lanzavecchia A: Mechanisms of antigen uptake for presentation. Curr Opin Immunol (1996) 8:348-354. Informative review detailing the concept of how DCs are able to function as both antigen processors and antigen presenters depending on their maturation stage.
    • (1996) Curr Opin Immunol , vol.8 , pp. 348-354
    • Lanzavecchia, A.1
  • 126
    • 0029913425 scopus 로고    scopus 로고
    • New insights into the mobilization and phagocytic activity of dendritic cells
    • Austyn JM: New insights into the mobilization and phagocytic activity of dendritic cells. J Exp Med (1996) 163:1287-1292.
    • (1996) J Exp Med , vol.163 , pp. 1287-1292
    • Austyn, J.M.1
  • 127
    • 0032482274 scopus 로고    scopus 로고
    • Immunology. Licence to kill
    • Lanzavecchia A: Immunology. Licence to kill. Nature (1998) 393:413-414.
    • (1998) Nature , vol.393 , pp. 413-414
    • Lanzavecchia, A.1
  • 128
    • 0032752777 scopus 로고    scopus 로고
    • Dendritic cells as natural adjuvants
    • Citterio S, Rescigno M, Foti M, Granucci F, Aggujaro D, Gasperi C, Matyszak MK, Girolomoni G, Ricciardi-Castagnoli P: Dendritic cells as natural adjuvants. Methods (1999) 19:142-147. A simple review showing the potential of DCs as cencer immunotherapy strategies, as well as detailing methods to purify, expand and mature DCs in vitro. Ricciardi-Castagnoli has published a series of papers in the field of DC research, in particular citing their use as adjuvants.
    • (1999) Methods , vol.19 , pp. 142-147
    • Citterio, S.1    Rescigno, M.2    Foti, M.3    Granucci, F.4    Aggujaro, D.5    Gasperi, C.6    Matyszak, M.K.7    Girolomoni, G.8    Ricciardi-Castagnoli, P.9
  • 129
    • 0034142253 scopus 로고    scopus 로고
    • Retrovirally transduced mouse dendritic cells require CD4+ T-cell help to elicit antitumor immunity: Implications for the clinical use of dendritic cells
    • Schnell S, Young JW, Houghton AN, Sadelain M: Retrovirally transduced mouse dendritic cells require CD4+ T-cell help to elicit antitumor immunity: Implications for the clinical use of dendritic cells. J Immunol (2000) 164:1243-1250.
    • (2000) J Immunol , vol.164 , pp. 1243-1250
    • Schnell, S.1    Young, J.W.2    Houghton, A.N.3    Sadelain, M.4
  • 130
    • 0034681178 scopus 로고    scopus 로고
    • Rapid antibody responses by low-dose, single-step, dendritic cell-targeted immunization
    • Wang H, Griffiths MM, Burton DR, Ghazal P: Rapid antibody responses by low-dose, single-step, dendritic cell-targeted immunization. Proc Natl Acad Sci USA (2000) 97:847-852.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 847-852
    • Wang, H.1    Griffiths, M.M.2    Burton, D.R.3    Ghazal, P.4
  • 133
    • 0033405438 scopus 로고    scopus 로고
    • Vaccination with mage-3A1 peptide-pulsed mature, monocyte-derived dendritic cells expands specific cytotoxic T-cells and induces regression of some metastases in advanced stage IV melanoma
    • Thumer B, Haendle I, Roder C, Dieckmann D, Kelkavoussi P, Jonuteit H, Bender A, Maczek C, Schreiner D, von den Driesch P, Brocker EB, Steinman RM, Enk A, Kampgen E, Schuler G: Vaccination with mage-3A1 peptide-pulsed mature, monocyte-derived dendritic cells expands specific cytotoxic T-cells and induces regression of some metastases in advanced stage IV melanoma. J Exp Med (1999) 190:1669-1678. Incisive and detailed report on a clinical trial using DCs as a vaccination therapy. The authors showed that this strategy was able to regress turnors and that this was due in part to CD8+ CTL infiltrates.
    • (1999) J Exp Med , vol.190 , pp. 1669-1678
    • Thumer, B.1    Haendle, I.2    Roder, C.3    Dieckmann, D.4    Kelkavoussi, P.5    Jonuteit, H.6    Bender, A.7    Maczek, C.8    Schreiner, D.9    Von Den Driesch, P.10    Brocker, E.B.11    Steinman, R.M.12    Enk, A.13    Kampgen, E.14    Schuler, G.15
  • 135
    • 0032745343 scopus 로고    scopus 로고
    • Interferon-γ and interleukin-12 mediate protection to acute Neospora caninum infection in BALB/c mice
    • Baszler TV, Long MT, McElwain TF, Mathison BA: Interferon-γ and interleukin-12 mediate protection to acute Neospora caninum infection in BALB/c mice. Int J Parasitol (1999) 29:1635-1646.
    • (1999) Int J Parasitol , vol.29 , pp. 1635-1646
    • Baszler, T.V.1    Long, M.T.2    McElwain, T.F.3    Mathison, B.A.4
  • 136
    • 0345718513 scopus 로고    scopus 로고
    • Interleukin-6 and Interleukin-12 participate in induction of a type 1 protective T-cell response during vaccination with a tuberculosis subunit vaccine
    • Leal IS, Smedegard B, Andersen P, Appelberg R: Interleukin-6 and Interleukin-12 participate in induction of a type 1 protective T-cell response during vaccination with a tuberculosis subunit vaccine. Infect Immun (1999) 67:5747-5754.
    • (1999) Infect Immun , vol.67 , pp. 5747-5754
    • Leal, I.S.1    Smedegard, B.2    Andersen, P.3    Appelberg, R.4
  • 137
    • 0033427204 scopus 로고    scopus 로고
    • Induction of antitumor immunity with modified autologous cells expressing membrane-bound murine cytokines
    • el-Shami KM, Tzehoval E, Vadai E, Feldman M, Eisenbach L: Induction of antitumor immunity with modified autologous cells expressing membrane-bound murine cytokines. J Interferon Cytokine Res (1999) 19:1391-1401.
    • (1999) J Interferon Cytokine Res , vol.19 , pp. 1391-1401
    • El-Shami, K.M.1    Tzehoval, E.2    Vadai, E.3    Feldman, M.4    Eisenbach, L.5
  • 138
    • 0032526346 scopus 로고    scopus 로고
    • Expanding dendritic cells in vivo enhances the induction of oral tolerance
    • Viney JL, Mowat AM, O'Malley JM, Williamson E, Fanger NA: Expanding dendritic cells in vivo enhances the induction of oral tolerance. J Immunol (1998) 160:5815-5825.
    • (1998) J Immunol , vol.160 , pp. 5815-5825
    • Viney, J.L.1    Mowat, A.M.2    O'Malley, J.M.3    Williamson, E.4    Fanger, N.A.5
  • 140
    • 0032883179 scopus 로고    scopus 로고
    • Generating a T-cell tumor-specific immune response in vivo: Can flt3-ligand-generated dendritic cells tip the balance?
    • McKenna HJ: Generating a T-cell tumor-specific immune response In vivo: Can flt3-ligand-generated dendritic cells tip the balance? Cancer Immunol Immunother (1999) 48:281-286.
    • (1999) Cancer Immunol Immunother , vol.48 , pp. 281-286
    • McKenna, H.J.1
  • 141
    • 0033572416 scopus 로고    scopus 로고
    • Flt3-ligand administration after radiation therapy prolongs survival in a murine model of metastatic lung cancer
    • Chakravarty PK, Alfieri A, Thomas EK, Beri V, Tanaka KE, Vikram B, Guha C: Flt3-ligand administration after radiation therapy prolongs survival in a murine model of metastatic lung cancer. Cancer Res (1999) 59:6028-6032.
    • (1999) Cancer Res , vol.59 , pp. 6028-6032
    • Chakravarty, P.K.1    Alfieri, A.2    Thomas, E.K.3    Beri, V.4    Tanaka, K.E.5    Vikram, B.6    Guha, C.7
  • 142
    • 0033199589 scopus 로고    scopus 로고
    • Flt3 ligand antitumor activity in a murine breast cancer model: A comparison with granulocyte-macrophage colony-stimulating factor and a potential mechanism of action
    • Braun SE, Chen K, Blazar BR, Orchard PJ, Sledge G, Robertson MJ, Broxmeyer HE, Cometta K: Flt3 ligand antitumor activity in a murine breast cancer model: A comparison with granulocyte-macrophage colony-stimulating factor and a potential mechanism of action. Hum Gene Ther (1999) 10:2141-2151.
    • (1999) Hum Gene Ther , vol.10 , pp. 2141-2151
    • Braun, S.E.1    Chen, K.2    Blazar, B.R.3    Orchard, P.J.4    Sledge, G.5    Robertson, M.J.6    Broxmeyer, H.E.7    Cometta, K.8
  • 143
    • 0033213958 scopus 로고    scopus 로고
    • Modulating dendritic cells to optimize mucosal immunization protocols
    • Williamson E, Westrich GM, Viney JL: Modulating dendritic cells to optimize mucosal immunization protocols. J Immunol (1999) 163:3668-3675.
    • (1999) J Immunol , vol.163 , pp. 3668-3675
    • Williamson, E.1    Westrich, G.M.2    Viney, J.L.3
  • 144
    • 0024353079 scopus 로고
    • H2 cells: Differential patterns of lymphokine secretion lead to differential functional properties
    • H2 cells: Differential patterns of lymphokine secretion lead to differential functional properties. Annu Rev Immunol (1989) 7:145-173.
    • (1989) Annu Rev Immunol , vol.7 , pp. 145-173
    • Mosmann, T.R.1    Coffman, R.L.2
  • 145
    • 0031128434 scopus 로고    scopus 로고
    • Functions of CDS T-cell subsets secreting different cytokine patterns
    • Mosmann TR, Li L, Sad S: Functions of CDS T-cell subsets secreting different cytokine patterns. Semin Immunol (1997) 9:87-92. A comprehensive review of T-cell cytokine-secreting patterns and their function.
    • (1997) Semin Immunol , vol.9 , pp. 87-92
    • Mosmann, T.R.1    Li, L.2    Sad, S.3
  • 146
    • 0033514943 scopus 로고    scopus 로고
    • Interferon γ expressed by a recombinant respiratory syncytial virus attenuates virus replication in mice without compromising immunogenicity
    • Bukreyev A, Whitehead SS, Bukreyeva N, Murphy BR, Collins PL: Interferon γ expressed by a recombinant respiratory syncytial virus attenuates virus replication in mice without compromising immunogenicity. Proc Natl Acad Sci USA (1999) 96:2367-2372.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 2367-2372
    • Bukreyev, A.1    Whitehead, S.S.2    Bukreyeva, N.3    Murphy, B.R.4    Collins, P.L.5
  • 147
    • 0029099861 scopus 로고
    • Interleukln-12 treatment during immunization elicits a T-helper cell type 1-like immune response in mice challenged with respiratory syncytial virus and improves vaccine immunogenicity
    • Tang YW, Graham BS: Interleukln-12 treatment during immunization elicits a T-helper cell type 1-like immune response in mice challenged with respiratory syncytial virus and improves vaccine immunogenicity. J Infect Dis (1995) 172:734-738.
    • (1995) J Infect Dis , vol.172 , pp. 734-738
    • Tang, Y.W.1    Graham, B.S.2
  • 148
    • 0031010847 scopus 로고    scopus 로고
    • T-cell source of type 1 cytokines determines illness patterns in respiratory syncytial virus-infected mice
    • Tang YW, Graham BS: T-cell source of type 1 cytokines determines illness patterns in respiratory syncytial virus-infected mice. J Clin Invest (1997) 99:2183-2191.
    • (1997) J Clin Invest , vol.99 , pp. 2183-2191
    • Tang, Y.W.1    Graham, B.S.2
  • 149
    • 0028110057 scopus 로고
    • Anti-IL-4 treatment at immunization modulates cytoklne expression, reduces illness, and increases cytotoxic T-lymphocyte activity in mice challenged with respiratory syncytial virus
    • Tang YW, Graham BS: Anti-IL-4 treatment at immunization modulates cytoklne expression, reduces illness, and increases cytotoxic T-lymphocyte activity in mice challenged with respiratory syncytial virus. J Clin Invest (1994) 94:1953-1958. One of a number of studies by Tang and Graham detalling how the Th1/Th2 balance can be manipulated to influence the immune response to a vaccine.
    • (1994) J Clin Invest , vol.94 , pp. 1953-1958
    • Tang, Y.W.1    Graham, B.S.2
  • 150
    • 0032875711 scopus 로고    scopus 로고
    • Interleukin-4 diminishes CD8(+) respiratory syncytial virus-specific cytotoxic T-lymphocyte activity in vivo
    • Aung S, Tang YW, Graham BS: Interleukin-4 diminishes CD8(+) respiratory syncytial virus-specific cytotoxic T-lymphocyte activity in vivo. J Virol (1999) 73:8944-8949.
    • (1999) J Virol , vol.73 , pp. 8944-8949
    • Aung, S.1    Tang, Y.W.2    Graham, B.S.3
  • 152
    • 0027989619 scopus 로고
    • Oral immunization with recombinant Salmonella typhimurium expressing surface protein antigen A of Streptococcus sobrinus: Persistence and induction of humoral responses in rats
    • Redman TK, Harmon CC, Michalek SM: Oral immunization with recombinant Salmonella typhimurium expressing surface protein antigen A of Streptococcus sobrinus: Persistence and induction of humoral responses in rats. Infect Immun (1994) 62:3162-3171.
    • (1994) Infect Immun , vol.62 , pp. 3162-3171
    • Redman, T.K.1    Harmon, C.C.2    Michalek, S.M.3
  • 154
    • 0344141395 scopus 로고    scopus 로고
    • The attenuated Salmonella vaccine approach for the control of Hellcobacter pylori-related diseases
    • Gomez-Duarte OG, Bumann D, Meyer TF: The attenuated Salmonella vaccine approach for the control of Hellcobacter pylori-related diseases. Vaccine (1999) 17:1667-1673.
    • (1999) Vaccine , vol.17 , pp. 1667-1673
    • Gomez-Duarte, O.G.1    Bumann, D.2    Meyer, T.F.3
  • 155
    • 0027048769 scopus 로고
    • Expression of hepatitis B surface antigen in transgenic plants
    • Mason HS, Lam DM-K, Arntzen CJ: Expression of hepatitis B surface antigen in transgenic plants. Proc Natl Acad Sci USA (1992) 87:11745-11749. First report of the production of foreign protein by a plant for use as an immunogen.
    • (1992) Proc Natl Acad Sci USA , vol.87 , pp. 11745-11749
    • Mason, H.S.1    Lam, D.M.-K.2    Arntzen, C.J.3
  • 157
    • 0029055060 scopus 로고
    • Oral immunization with a recombinant bacterial antigen produced in transgenic plants
    • Haq TA, Mason HS, Clements JD, Amtzen CJ: Oral immunization with a recombinant bacterial antigen produced in transgenic plants. Science (1995) 268:714-716.
    • (1995) Science , vol.268 , pp. 714-716
    • Haq, T.A.1    Mason, H.S.2    Clements, J.D.3    Amtzen, C.J.4
  • 159
    • 0029891823 scopus 로고    scopus 로고
    • Expression of Norwalk virus capsid protein in transgenic tobacco and potato and its oral immunogenlcity in mice
    • Mason HS, Ball JM, Shi JJ, Jiang X, Estes MK, Arntzen CJ: Expression of Norwalk virus capsid protein in transgenic tobacco and potato and its oral immunogenlcity in mice. Proc Natl Acad Sci USA (1996) 93:5335-5340
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 5335-5340
    • Mason, H.S.1    Ball, J.M.2    Shi, J.J.3    Jiang, X.4    Estes, M.K.5    Arntzen, C.J.6
  • 161
    • 0031863854 scopus 로고    scopus 로고
    • Immunogenicity in humans of a recombinant bacterial antigen delivered in a transgenic potato
    • Tacket CO, Mason HS, Losonsky G, Clements JD, Levine MM, Amtzen CJ: Immunogenicity in humans of a recombinant bacterial antigen delivered in a transgenic potato. Nature Med (1998) 4:607-609. NIH sponsored phase I 'proof-of-concept' clinical trial using potatoes expressing Escherichia coll toxin as an immunogen. Subjects were fed raw potato and then studied for both serum and stool antibody responses - Indicative of systemic and localized mucosal responses.
    • (1998) Nature Med , vol.4 , pp. 607-609
    • Tacket, C.O.1    Mason, H.S.2    Losonsky, G.3    Clements, J.D.4    Levine, M.M.5    Amtzen, C.J.6
  • 162
    • 0344339017 scopus 로고    scopus 로고
    • Protection of mice against challenge with foot and mouth disease virus (FMDV) by immunization with foliar extracts from plants infected with recombinant tobacco mosaic virus expressing the FMDV structural protein VP1
    • Wigdorovitz A, Perez Filguelra DM, Robertson N, Carrillo C, Sadir AM, Morris TJ, Borca MV: Protection of mice against challenge with foot and mouth disease virus (FMDV) by immunization with foliar extracts from plants infected with recombinant tobacco mosaic virus expressing the FMDV structural protein VP1. Virology (1999) 264:85-91.
    • (1999) Virology , vol.264 , pp. 85-91
    • Wigdorovitz, A.1    Perez Filguelra, D.M.2    Robertson, N.3    Carrillo, C.4    Sadir, A.M.5    Morris, T.J.6    Borca, M.V.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.