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Volumn 2, Issue 9, 2001, Pages 659-668

The art and design of genetic screens: Yeast

Author keywords

[No Author keywords available]

Indexed keywords

EUKARYOTA; SCHIZOSACCHAROMYCETACEAE;

EID: 0035458366     PISSN: 14710056     EISSN: None     Source Type: Journal    
DOI: 10.1038/35088500     Document Type: Review
Times cited : (195)

References (47)
  • 1
    • 10244239321 scopus 로고    scopus 로고
    • Life with 6000 genes
    • Goffeau, A. et al. Life with 6000 genes. Science 274, 546-567 (1996).
    • (1996) Science , vol.274 , pp. 546-567
    • Goffeau, A.1
  • 2
    • 0018180547 scopus 로고
    • Transformation of yeast by a replicating hybrid plasmid
    • Beggs, J. D. Transformation of yeast by a replicating hybrid plasmid. Nature 275, 104-109 (1978).
    • (1978) Nature , vol.275 , pp. 104-109
    • Beggs, J.D.1
  • 3
    • 0020645054 scopus 로고
    • One step gene disruption in yeast
    • Rothstein, R. One step gene disruption in yeast. Methods Enzymol. 101, 202-211 (1983).
    • (1983) Methods Enzymol. , vol.101 , pp. 202-211
    • Rothstein, R.1
  • 4
    • 0030750492 scopus 로고    scopus 로고
    • From gene to screen with yeast
    • Oliver, S. G. From gene to screen with yeast. Curr. Opin. Genet. Dev. 7, 405-409 (1997).
    • (1997) Curr. Opin. Genet. Dev. , vol.7 , pp. 405-409
    • Oliver, S.G.1
  • 6
    • 0029150840 scopus 로고
    • Phylogenesis of fission yeasts -contradictions surrounding the origin of a century old genus
    • Sipiczki, M. Phylogenesis of fission yeasts -contradictions surrounding the origin of a century old genus. Antonie Van Leeuwenhoek 68, 119-149 (1995).
    • (1995) Antonie Van Leeuwenhoek , vol.68 , pp. 119-149
    • Sipiczki, M.1
  • 7
    • 0030993742 scopus 로고    scopus 로고
    • The fungal mitochondrial genome project: Evolution of fungal mitochondrial genomes and their gene expression
    • Paquin, B. et al. The fungal mitochondrial genome project: evolution of fungal mitochondrial genomes and their gene expression. Curr. Genet. 31, 380-395 (1997).
    • (1997) Curr. Genet. , vol.31 , pp. 380-395
    • Paquin, B.1
  • 8
    • 0027883238 scopus 로고
    • Dating the evolutionary radiations of the true fungi
    • Berbee, M. L. & Taylor, J. W. Dating the evolutionary radiations of the true fungi. Can. J. Bot. 71, 1114-1127 (1993).
    • (1993) Can. J. Bot. , vol.71 , pp. 1114-1127
    • Berbee, M.L.1    Taylor, J.W.2
  • 9
    • 0032579778 scopus 로고    scopus 로고
    • Evolution of gene order and chromosome number in Saccharomyces, Kluyveromyces and related fungi
    • Keogh, R. S., Seoighe, C. & Wolfe, K. H. Evolution of gene order and chromosome number in Saccharomyces, Kluyveromyces and related fungi. Yeast 14, 443-457 (1998).
    • (1998) Yeast , vol.14 , pp. 443-457
    • Keogh, R.S.1    Seoighe, C.2    Wolfe, K.H.3
  • 10
    • 0033199801 scopus 로고    scopus 로고
    • The best yeast
    • Forsburg, S. L. The best yeast. Trends Genet. 15, 340-344 (1999). Summarizes some differences in the biology of the two yeast species.
    • (1999) Trends Genet. , vol.15 , pp. 340-344
    • Forsburg, S.L.1
  • 11
    • 0025994140 scopus 로고
    • Guide to yeast genetics and molecular biology
    • Guthrie, C. & Fink, G. R. (eds) Guide to yeast genetics and molecular biology. Methods Enzymol. 194, 1-863 (1991). Describes more specific methods and protocols for both yeast species.
    • (1991) Methods Enzymol. , vol.194 , pp. 1-863
    • Guthrie, C.1    Fink, G.R.2
  • 12
    • 0026025891 scopus 로고
    • Molecular genetic analysis of the fission yeast Schizosaccharomyces pombe
    • Moreno, S., Klar, A. & Nurse, P. Molecular genetic analysis of the fission yeast Schizosaccharomyces pombe. Methods Enzymol. 194, 795-823 (1991).
    • (1991) Methods Enzymol. , vol.194 , pp. 795-823
    • Moreno, S.1    Klar, A.2    Nurse, P.3
  • 13
    • 0035319601 scopus 로고    scopus 로고
    • Emerging technologies in yeast genomics
    • Kumar, A. & Snyder, M. Emerging technologies in yeast genomics. Nature Rev. Genet. 2, 302-312 (2001). The genomics revolution complements the classical genetics approach.
    • (2001) Nature Rev. Genet. , vol.2 , pp. 302-312
    • Kumar, A.1    Snyder, M.2
  • 14
    • 0034054269 scopus 로고    scopus 로고
    • Mutagenesis and gene cloning in Schizosaccharomyces pombe using nonhomologous plasmid integration and rescue
    • Hoffman, C. S. & Welton, R. Mutagenesis and gene cloning in Schizosaccharomyces pombe using nonhomologous plasmid integration and rescue. Biotechniques 28, 532-539 (2000).
    • (2000) Biotechniques , vol.28 , pp. 532-539
    • Hoffman, C.S.1    Welton, R.2
  • 15
    • 0034200889 scopus 로고    scopus 로고
    • Insertional mutagenesis based on illegitimate recombination in Schizosaccharomyces pombe
    • Chua, G., Taricani, L., Strangle, W. & Young, P. G. Insertional mutagenesis based on illegitimate recombination in Schizosaccharomyces pombe. Nucleic Acids Res. 28, E53 (2000).
    • (2000) Nucleic Acids Res. , vol.28
    • Chua, G.1    Taricani, L.2    Strangle, W.3    Young, P.G.4
  • 16
    • 0027299203 scopus 로고
    • A study of integrative transformation in Schizosaccharomyces pombe
    • Grallert, B., Nurse, P. & Patterson, T. E. A study of integrative transformation in Schizosaccharomyces pombe. Mol. Gen. Genet. 238, 26-32 (1993).
    • (1993) Mol. Gen. Genet. , vol.238 , pp. 26-32
    • Grallert, B.1    Nurse, P.2    Patterson, T.E.3
  • 17
    • 17444446946 scopus 로고    scopus 로고
    • Widespread aneuploidy revealed by DNA microarray expression profiling
    • Hughes, T. R. et al. Widespread aneuploidy revealed by DNA microarray expression profiling. Nature Genet. 25, 333-337 (2000).
    • (2000) Nature Genet. , vol.25 , pp. 333-337
    • Hughes, T.R.1
  • 18
    • 0030947344 scopus 로고    scopus 로고
    • Molecular evidence for an ancient duplication of the entire yeast genome
    • Wolfe, K. H. & Shields, D. C. Molecular evidence for an ancient duplication of the entire yeast genome. Nature 387, 708-713 (1997).
    • (1997) Nature , vol.387 , pp. 708-713
    • Wolfe, K.H.1    Shields, D.C.2
  • 19
    • 0033048778 scopus 로고    scopus 로고
    • Genomic profiling of drug sensitivities via induced haploinsufficiency
    • Giaever, G. et al. Genomic profiling of drug sensitivities via induced haploinsufficiency. Nature Genet. 21, 278-283 (1999).
    • (1999) Nature Genet. , vol.21 , pp. 278-283
    • Giaever, G.1
  • 20
    • 0014804012 scopus 로고
    • Genetic control of the cell division cycle in yeast. I. Detection of mutants
    • Hartwell, L., Culotti, J. & Reid, B. Genetic control of the cell division cycle in yeast. I. Detection of mutants. Proc. Natl Acad. Sci. USA 66, 352-359 (1970).
    • (1970) Proc. Natl Acad. Sci. USA , vol.66 , pp. 352-359
    • Hartwell, L.1    Culotti, J.2    Reid, B.3
  • 21
    • 0016793098 scopus 로고
    • Genetic control of cell size at cell division in yeast
    • Nurse, P. Genetic control of cell size at cell division in yeast. Nature 256, 547-551 (1975).
    • (1975) Nature , vol.256 , pp. 547-551
    • Nurse, P.1
  • 22
    • 0025246110 scopus 로고
    • Universal control mechanism regulating onset of M phase
    • Nurse, P. Universal control mechanism regulating onset of M phase. Nature 344, 503-508 (1990).
    • (1990) Nature , vol.344 , pp. 503-508
    • Nurse, P.1
  • 23
    • 0026482601 scopus 로고
    • Fission yeast genes involved in coupling mitosis to completion of DNA replication
    • Enoch, T., Carr, A. M. & Nurse, P. Fission yeast genes involved in coupling mitosis to completion of DNA replication. Genes Dev. 6, 2035-2046 (1992).
    • (1992) Genes Dev. , vol.6 , pp. 2035-2046
    • Enoch, T.1    Carr, A.M.2    Nurse, P.3
  • 24
    • 0026009964 scopus 로고
    • Feedback control of mitosis in budding yeast
    • Li, R. & Murray, A. W. Feedback control of mitosis in budding yeast. Cell 66, 519-532 (1991).
    • (1991) Cell , vol.66 , pp. 519-532
    • Li, R.1    Murray, A.W.2
  • 25
    • 0025941405 scopus 로고
    • S. cerevisiae genes required for cell cycle arrest in response to loss of microtubule function
    • Hoyt, M. A., Totis, L. & Roberts, B. T. S. cerevisiae genes required for cell cycle arrest in response to loss of microtubule function. Cell 66, 507-517 (1991).
    • (1991) Cell , vol.66 , pp. 507-517
    • Hoyt, M.A.1    Totis, L.2    Roberts, B.T.3
  • 26
    • 0021906691 scopus 로고
    • Genetic analysis of the mitotic transmission of minichromosomes
    • Koshland, D., Kent, J. C. & Hartwell, L. H. Genetic analysis of the mitotic transmission of minichromosomes. Cell 40, 393-403 (1985).
    • (1985) Cell , vol.40 , pp. 393-403
    • Koshland, D.1    Kent, J.C.2    Hartwell, L.H.3
  • 27
    • 0021906690 scopus 로고
    • Mitotic stability of yeast chromosomes: A colony color assay that measures nondisjunction and chromosome loss
    • Hieter, P., Mann, C., Snyder, M. & Davis, R. W. Mitotic stability of yeast chromosomes: a colony color assay that measures nondisjunction and chromosome loss. Cell 40, 381-382 (1985).
    • (1985) Cell , vol.40 , pp. 381-382
    • Hieter, P.1    Mann, C.2    Snyder, M.3    Davis, R.W.4
  • 28
    • 0025980956 scopus 로고
    • Gene overexpression in studies of Saccharomyces cerevisiae
    • Rine, J. Gene overexpression in studies of Saccharomyces cerevisiae. Methods Enzymol. 194, 239-251 (1991).
    • (1991) Methods Enzymol. , vol.194 , pp. 239-251
    • Rine, J.1
  • 29
    • 0035957433 scopus 로고    scopus 로고
    • A large-scale overexpression screen in Saccharomyces cerevisiae identifies previously uncharacterized cell cycle genes
    • Stevenson, L. F., Kennedy, B. K. & Harlow, E. A large-scale overexpression screen in Saccharomyces cerevisiae identifies previously uncharacterized cell cycle genes. Proc. Natl Acad. Sci. USA 98, 3946-3951 (2001).
    • (2001) Proc. Natl Acad. Sci. USA , vol.98 , pp. 3946-3951
    • Stevenson, L.F.1    Kennedy, B.K.2    Harlow, E.3
  • 30
    • 0023239517 scopus 로고
    • Functional inactivation of genes by dominant negative mutations
    • Herskowitz, I. Functional inactivation of genes by dominant negative mutations. Nature 329, 219-222 (1937).
    • (1937) Nature , vol.329 , pp. 219-222
    • Herskowitz, I.1
  • 31
    • 0033168997 scopus 로고    scopus 로고
    • Suppression mechanisms: Themes from variations
    • Prelich, G. Suppression mechanisms: themes from variations. Trends Genet. 15, 261-266 (1999).
    • (1999) Trends Genet. , vol.15 , pp. 261-266
    • Prelich, G.1
  • 32
    • 0027515605 scopus 로고
    • Synthetic enhancement in gene interaction: A genetic tool come of age
    • Guarente, L. Synthetic enhancement in gene interaction: a genetic tool come of age. Trends Genet. 9, 362-366 (1993). References 28 and 30-32 are classic reviews describing the main features of the screens covered In this article and providing some theoretical background.
    • (1993) Trends Genet. , vol.9 , pp. 362-366
    • Guarente, L.1
  • 33
  • 34
    • 0030734377 scopus 로고    scopus 로고
    • Allele-specific suppression by formation of new protein-protein interactions in yeast
    • Sandrock, T. M., O'Dell, J. L. & Adams, A. E. Allele-specific suppression by formation of new protein-protein interactions in yeast. Genetics 147, 1635-1642 (1997).
    • (1997) Genetics , vol.147 , pp. 1635-1642
    • Sandrock, T.M.1    O'Dell, J.L.2    Adams, A.E.3
  • 35
    • 0034634533 scopus 로고    scopus 로고
    • The hexameric eukaryotic MCM helicase: Building symmetry from nonidentical parts
    • Tye, B. K. & Sawyer, S. The hexameric eukaryotic MCM helicase: building symmetry from nonidentical parts. J. Biol. Chem. 275, 34833-34836 (2000).
    • (2000) J. Biol. Chem. , vol.275 , pp. 34833-34836
    • Tye, B.K.1    Sawyer, S.2
  • 37
    • 0023647143 scopus 로고
    • Complementation used to clone a human homologue of the fission yeast cell cycle control gene cdc2
    • Lee, M. G. & Nurse, P. Complementation used to clone a human homologue of the fission yeast cell cycle control gene cdc2. Nature 327, 31-35 (1937).
    • (1937) Nature , vol.327 , pp. 31-35
    • Lee, M.G.1    Nurse, P.2
  • 38
    • 0030826573 scopus 로고    scopus 로고
    • An approach to identify functional homologues and suppressors of genes in fission yeast
    • Grallert, B. & Nurse, P. An approach to identify functional homologues and suppressors of genes in fission yeast. Curr. Genet. 32, 27-31 (1997).
    • (1997) Curr. Genet. , vol.32 , pp. 27-31
    • Grallert, B.1    Nurse, P.2
  • 40
    • 0025821897 scopus 로고
    • A group of interacting yeast DNA replication genes
    • Hennessy, K. M., Lee, A., Chen, E. & Botstein, D. A group of interacting yeast DNA replication genes. Genes Dev. 5, 958-969 (1991).
    • (1991) Genes Dev. , vol.5 , pp. 958-969
    • Hennessy, K.M.1    Lee, A.2    Chen, E.3    Botstein, D.4
  • 41
    • 0029870293 scopus 로고    scopus 로고
    • Establishing genetic interactions by a synthetic dosage lethality phenotype
    • Kroll, E. S., Hyland, K. M., Hieter, P. & Li, J. J. Establishing genetic interactions by a synthetic dosage lethality phenotype. Genetics 143, 95-102 (1996).
    • (1996) Genetics , vol.143 , pp. 95-102
    • Kroll, E.S.1    Hyland, K.M.2    Hieter, P.3    Li, J.J.4
  • 42
    • 0032760517 scopus 로고    scopus 로고
    • Nuclear localization of fission yeast Mcm2/Cdc19p requires MCM complex formation
    • Pasion, S. G. & Forsburg, S. L. Nuclear localization of fission yeast Mcm2/Cdc19p requires MCM complex formation. Mol. Biol. Cell 10, 4043-4057 (1999).
    • (1999) Mol. Biol. Cell , vol.10 , pp. 4043-4057
    • Pasion, S.G.1    Forsburg, S.L.2
  • 43
    • 0032054999 scopus 로고    scopus 로고
    • Centromeres: Proteins, protein complexes, and repeated domains at centromeres of simple eukaryotes
    • Clarke, L. Centromeres: proteins, protein complexes, and repeated domains at centromeres of simple eukaryotes. Curr. Opin. Genet. Dev. 8, 212-218 (1998).
    • (1998) Curr. Opin. Genet. Dev. , vol.8 , pp. 212-218
    • Clarke, L.1
  • 44
    • 0026090063 scopus 로고
    • In vitro mutagenesis and plasmid shuffling: From cloned gene to mutant yeast
    • Sikorski, R. S. & Boeke, J. D. In vitro mutagenesis and plasmid shuffling: from cloned gene to mutant yeast. Methods Enzymol. 194, 302-318 (1991).
    • (1991) Methods Enzymol. , vol.194 , pp. 302-318
    • Sikorski, R.S.1    Boeke, J.D.2
  • 45
    • 0346495923 scopus 로고    scopus 로고
    • + (MCM10) and interactions with replication checkpoints
    • in the press
    • + (MCM10) and interactions with replication checkpoints. Genetics (in the press).
    • Genetics
    • Liang, D.T.1    Forsburg, S.L.2
  • 46
    • 0033664379 scopus 로고    scopus 로고
    • The yeast genome: On the road to the Golden Age
    • Johnston, M. The yeast genome: on the road to the Golden Age. Curr. Opin. Genet. Dev. 10, 617-623 (2000).
    • (2000) Curr. Opin. Genet. Dev. , vol.10 , pp. 617-623
    • Johnston, M.1
  • 47
    • 0035148955 scopus 로고    scopus 로고
    • Requirement for three novel protein complexes in the absence of the Sgs1 DNA helicase in Saccharomyces cerevisiae
    • Mullen, J. R., Kaliaraman, V., Ibrahim, S. S. & Brill, S. J. Requirement for three novel protein complexes in the absence of the Sgs1 DNA helicase in Saccharomyces cerevisiae. Genetics 157, 103-118 (2001). An excellent example of a synthetic lethal screen and plasmid shuffle analysis.
    • (2001) Genetics , vol.157 , pp. 103-118
    • Mullen, J.R.1    Kaliaraman, V.2    Ibrahim, S.S.3    Brill, S.J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.