-
1
-
-
0033938994
-
Recurring views on the structure and function of the cytoskeleton: A 300 year epic
-
Frixione E. Recurring views on the structure and function of the cytoskeleton: a 300 year epic. Cell Motil Cytoskeleton 2000;46:73-94.
-
(2000)
Cell Motil Cytoskeleton
, vol.46
, pp. 73-94
-
-
Frixione, E.1
-
2
-
-
0029037739
-
Protein molecules as computational elements in living cells
-
Bray D. Protein molecules as computational elements in living cells. Nature 1995;376:307-312.
-
(1995)
Nature
, vol.376
, pp. 307-312
-
-
Bray, D.1
-
3
-
-
0032702258
-
Proteins that regulate dynamic actin remodeling in response to membrane signaling
-
Yin HL, Stull JT. Proteins that regulate dynamic actin remodeling in response to membrane signaling. J Biol Chem 1999;174:32529-32530.
-
(1999)
J Biol Chem
, vol.174
, pp. 32529-32530
-
-
Yin, H.L.1
Stull, J.T.2
-
4
-
-
0032480279
-
Three-dimensional segregation of supramolecular activation clusters in T cells
-
Monks CR, Freiberg BA, Kupfer H, Sciaky N, Kupfer A. Three-dimensional segregation of supramolecular activation clusters in T cells. Nature 1998;395:82-86.
-
(1998)
Nature
, vol.395
, pp. 82-86
-
-
Monks, C.R.1
Freiberg, B.A.2
Kupfer, H.3
Sciaky, N.4
Kupfer, A.5
-
5
-
-
0032568580
-
Visualizing the dynamics of T cell activation: Intracellular adhesion molecule 1 migrates rapidly to the T cell/B cell interface and acts to sustain calcium levels
-
Wülfing C, Sjaastad MD, Davis MM. Visualizing the dynamics of T cell activation: intracellular adhesion molecule 1 migrates rapidly to the T cell/B cell interface and acts to sustain calcium levels. Proc Nat/Acad Sci USA 1998;95:6302-6307.
-
(1998)
Proc Nat/Acad Sci USA
, vol.95
, pp. 6302-6307
-
-
Wülfing, C.1
Sjaastad, M.D.2
Davis, M.M.3
-
6
-
-
0032545218
-
A receptor/cytoskeletal movement triggered by costimulation during T cell activation
-
Wülfing C, Davis MM. A receptor/cytoskeletal movement triggered by costimulation during T cell activation. Science 1998;282:2266-2269.
-
(1998)
Science
, vol.282
, pp. 2266-2269
-
-
Wülfing, C.1
Davis, M.M.2
-
7
-
-
0027937223
-
Isolation of a novel gene mutated in Wiskott-Aldrich syndrome
-
Derry JM, Ochs HD, Francke U. Isolation of a novel gene mutated in Wiskott-Aldrich syndrome. Cell 1994;79:635-644.
-
(1994)
Cell
, vol.79
, pp. 635-644
-
-
Derry, J.M.1
Ochs, H.D.2
Francke, U.3
-
8
-
-
0014276174
-
Wiskott-Aldrich syndrome. An immunologic deficiency disease involving the afferent limb of immunity
-
Cooper MD, Chae HP, Lowman JT, Krivit W, Good RA. Wiskott-Aldrich syndrome. An immunologic deficiency disease involving the afferent limb of immunity. Am J Med 1968;44:499-513.
-
(1968)
Am J Med
, vol.44
, pp. 499-513
-
-
Cooper, M.D.1
Chae, H.P.2
Lowman, J.T.3
Krivit, W.4
Good, R.A.5
-
9
-
-
0029988146
-
Defects in Wiskott-Aldrich syndrome blood cells
-
Remold-O'Donnell E, Rosen FS, Kenney DM. Defects in Wiskott-Aldrich syndrome blood cells. Blood 1996;87:2621-2631.
-
(1996)
Blood
, vol.87
, pp. 2621-2631
-
-
Remold-O'Donnell, E.1
Rosen, F.S.2
Kenney, D.M.3
-
10
-
-
0030816363
-
Defective actin reorganization and polymerization of Wiskott-Aldrich T cells in response to CD3-mediated stimulation
-
Galego MD, Santamaria M, Pena J, Molina IJ. Defective actin reorganization and polymerizationof Wiskott-Aldrich T cells in response to CD3-mediated stimulation. Blood 1997;90:3089-3097.
-
(1997)
Blood
, vol.90
, pp. 3089-3097
-
-
Galego, M.D.1
Santamaria, M.2
Pena, J.3
Molina, I.J.4
-
11
-
-
0030824870
-
Flow cytometric analysis of platelets from children with the Wiskott-Aldrich syndrome reveals defects in platelet development, activation and structure
-
Semple JW, et al. Flow cytometric analysis of platelets from children with the Wiskott-Aldrich syndrome reveals defects in platelet development, activation and structure. Br J Haematol 1997;97:747-754.
-
(1997)
Br J Haematol
, vol.97
, pp. 747-754
-
-
Semple, J.W.1
-
12
-
-
0023919711
-
Wiskott-Aldrich syndrome: New perspectives in pathogenesis and management
-
Standen GR. Wiskott-Aldrich syndrome: new perspectives in pathogenesis and management. J R Coll Physicians London 1988;22:80-83.
-
(1988)
J R Coll Physicians London
, vol.22
, pp. 80-83
-
-
Standen, G.R.1
-
14
-
-
0029999252
-
Wiskott-Aldrich syndrome: No strict genotype-phenotype correlations but clustering of missense mutations in the amino-terminal part of the WASp gene product
-
Schindelhauer D, et al. Wiskott-Aldrich syndrome: no strict genotype-phenotype correlations but clustering of missense mutations in the amino-terminal part of the WASp gene product. Hum Genet 1996;98:68-76.
-
(1996)
Hum Genet
, vol.98
, pp. 68-76
-
-
Schindelhauer, D.1
-
15
-
-
0029998118
-
Identification of WASp mutations, mutation hotspots and genotype-phenotype disparities in 24 patients with the Wiskott-Aldrich syndrome
-
Greer WL, Shehabeldin A, Schulman J, Junker A, Siminovitch KA. Identification of WASp mutations, mutation hotspots and genotype-phenotype disparities in 24 patients with the Wiskott-Aldrich syndrome. Hum Genet 1996;98:685-690.
-
(1996)
Hum Genet
, vol.98
, pp. 685-690
-
-
Greer, W.L.1
Shehabeldin, A.2
Schulman, J.3
Junker, A.4
Siminovitch, K.A.5
-
16
-
-
0034943052
-
Protein assays for diagnosis of Wiskott-Aldrich syndrome and X-linked thrombocytopenia
-
Qasim W, et al. Protein assays for diagnosis of Wiskott-Aldrich syndrome and X-linked thrombocytopenia. Br J Haematol 2001;113:861-865.
-
(2001)
Br J Haematol
, vol.113
, pp. 861-865
-
-
Qasim, W.1
-
17
-
-
0029982620
-
Studies of the expression of the Wiskott-Aldrich syndrome protein
-
Stewart DM, Treiber-Held S, Kurman CC, Facchetti F, Notarangelo LD, Nelson DL. Studies of the expression of the Wiskott-Aldrich syndrome protein. J Clin Invest 1996;97:2627-2634.
-
(1996)
J Clin Invest
, vol.97
, pp. 2627-2634
-
-
Stewart, D.M.1
Treiber-Held, S.2
Kurman, C.C.3
Facchetti, F.4
Notarangelo, L.D.5
Nelson, D.L.6
-
18
-
-
0029815611
-
2-dependent manner downstream of tyrosine kinases
-
2-dependent manner downstream of tyrosine kinases. EMBO J 1996;15:5326-5335.
-
(1996)
EMBO J
, vol.15
, pp. 5326-5335
-
-
Miki, H.1
Miura, K.2
Takenawa, T.3
-
19
-
-
0032494137
-
SCAR a WASp-related protein, isolated as a suppressor of receptor defects in late Dictyostelium development
-
Bear JE, Rawls JF, Saxe CL III. SCAR, a WASp-related protein, isolated as a suppressor of receptor defects in late Dictyostelium development. J Cell Biol 1998;142:1325-1335.
-
(1998)
J Cell Biol
, vol.142
, pp. 1325-1335
-
-
Bear, J.E.1
Rawls, J.F.2
Saxe C.L. III3
-
20
-
-
0032403083
-
WAVE, a novel WASp family protein involved in actin reorganization induced by Rac
-
Miki H, Suetsugu S, Takenawa T. WAVE, a novel WASp family protein involved in actin reorganization induced by Rac. EMBO J 1998;23:6932-6941.
-
(1998)
EMBO J
, vol.23
, pp. 6932-6941
-
-
Miki, H.1
Suetsugu, S.2
Takenawa, T.3
-
21
-
-
0033600187
-
Identification of two human WAVE/SCAR homologues as general actin regulatory molecules which associate with the Arp 2/3 complex
-
Suetsugu S, Miki H, Takenawa T. Identification of two human WAVE/SCAR homologues as general actin regulatory molecules which associate with the Arp 2/3 complex. Biochem Biophys Res Commun 1999;260:296-302.
-
(1999)
Biochem Biophys Res Commun
, vol.260
, pp. 296-302
-
-
Suetsugu, S.1
Miki, H.2
Takenawa, T.3
-
22
-
-
0035825181
-
WASp, the Drosophila Wiskott-Aldrich syndrome gene homologue, is required for cell fate decisions mediated by Notch signaling
-
Ben-Yaacov S, Le Borgne R, Abramson I, Schweisguth F, Schejter ED. WASp, the Drosophila Wiskott-Aldrich syndrome gene homologue, is required for cell fate decisions mediated by Notch signaling. J Cell Biol 2001;152:1-13.
-
(2001)
J Cell Biol
, vol.152
, pp. 1-13
-
-
Ben-Yaacov, S.1
Le Borgne, R.2
Abramson, I.3
Schweisguth, F.4
Schejter, E.D.5
-
23
-
-
0031045512
-
Beel, a yeast protein with homology to Wiskott-Aldrich syndrome protein, is critical for the assembly of cortical actin cytoskeleton
-
Li R. Beel, a yeast protein with homology to Wiskott-Aldrich syndrome protein, is critical for the assembly of cortical actin cytoskeleton. J Cell Biol 1997;136:649-658.
-
(1997)
J Cell Biol
, vol.136
, pp. 649-658
-
-
Li, R.1
-
24
-
-
0030592559
-
Mena, a relative of WASp and Drosophila Enabled, is implicated in the control of microfilament dynamics
-
Gertler FB, Niebuhr K, Reinhard M, Wehland J, Soriano P. Mena, a relative of WASp and Drosophila Enabled, is implicated in the control of microfilament dynamics. Cell 1996;87:227-239.
-
(1996)
Cell
, vol.87
, pp. 227-239
-
-
Gertler, F.B.1
Niebuhr, K.2
Reinhard, M.3
Wehland, J.4
Soriano, P.5
-
25
-
-
0033551783
-
The EVH2 domain of the vasodilator-stimulated phosphoprotein mediates tetramerization, F-actin binding and actin bundle formation
-
Bachmann C, Fisher L, Walter U, Reinhard M. The EVH2 domain of the vasodilator-stimulated phosphoprotein mediates tetramerization, F-actin binding and actin bundle formation. J Biol Chem 1999;174:23549-23557.
-
(1999)
J Biol Chem
, vol.174
, pp. 23549-23557
-
-
Bachmann, C.1
Fisher, L.2
Walter, U.3
Reinhard, M.4
-
26
-
-
0030970135
-
Homer: A protein that selectively binds metabotropic glutamate receptors
-
Brakeman PR, et al. Homer: a protein that selectively binds metabotropic glutamate receptors. Nature 1997;386:284-288.
-
(1997)
Nature
, vol.386
, pp. 284-288
-
-
Brakeman, P.R.1
-
27
-
-
0037157144
-
An EVH1/WH1 domain as a key actor in TGFβ signaling
-
Callebaut I. An EVH1/WH1 domain as a key actor in TGFβ signaling. FEBS Lett 2002;519:178-180.
-
(2002)
FEBS Lett
, vol.519
, pp. 178-180
-
-
Callebaut, I.1
-
28
-
-
0030864520
-
A novel proline-rich motif present in ActA of Listeria monocytogenes and cytoskeletal proteins is the ligand for the EVH1 domain, a protein module present in the Ena/VASP family
-
Niebuhr K, et al. A novel proline-rich motif present in ActA of Listeria monocytogenes and cytoskeletal proteins is the ligand for the EVH1 domain, a protein module present in the Ena/VASP family. EMBO J 1997;16:5433-5444.
-
(1997)
EMBO J
, vol.16
, pp. 5433-5444
-
-
Niebuhr, K.1
-
29
-
-
0033031122
-
Structure of EVH1, a novel proline-rich ligand-binding module involved in cytoskeletal dynamics and neural function
-
Fedorov AA, Fedorov E, Gertler F, Almo SC. Structure of EVH1, a novel proline-rich ligand-binding module involved in cytoskeletal dynamics and neural function. Nat Struct Biol 1999;6:661-665.
-
(1999)
Nat Struct Biol
, vol.6
, pp. 661-665
-
-
Fedorov, A.A.1
Fedorov, E.2
Gertler, F.3
Almo, S.C.4
-
30
-
-
0028148629
-
Structural determinants of peptide-binding orientation and of sequence specificity in SH3 domains
-
Lim WA, Richards FM, Fox RO. Structural determinants of peptide-binding orientation and of sequence specificity in SH3 domains. Nature 1994;372:375-379.
-
(1994)
Nature
, vol.372
, pp. 375-379
-
-
Lim, W.A.1
Richards, F.M.2
Fox, R.O.3
-
31
-
-
0037112347
-
Structure of the N-WASp EVH1 domain-WIP complex. Insight into the molecular basis of Wiskott-Aldrich syndrome
-
Volkman BF, Prehoda KE, Scott JA, Peterson FC, Lim WA. Structure of the N-WASp EVH1 domain-WIP complex. Insight into the molecular basis of Wiskott-Aldrich syndrome. Cell 2002;11:565-576.
-
(2002)
Cell
, vol.11
, pp. 565-576
-
-
Volkman, B.F.1
Prehoda, K.E.2
Scott, J.A.3
Peterson, F.C.4
Lim, W.A.5
-
32
-
-
0031446340
-
WIP a protein associated with Wiskott-Aldrich syndrome protein, induces actin polymerization and redistribution in lymphoid cells
-
Ramesh N, Anton IM, Hartwig JH, Geha RS. WIP, a protein associated with Wiskott-Aldrich syndrome protein, induces actin polymerization and redistribution in lymphoid cells. Proc Natl Acad Sci USA 1997;94:14471-14676.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 14471-14676
-
-
Ramesh, N.1
Anton, I.M.2
Hartwig, J.H.3
Geha, R.S.4
-
33
-
-
0035003138
-
WIP regulates N-WASp-mediated actin polymerization and filopodium formation
-
Martinez-Quiles N, et al. WIP regulates N-WASp-mediated actin polymerization and filopodium formation. Nat Cell Biol 2001;3:484-491.
-
(2001)
Nat Cell Biol
, vol.3
, pp. 484-491
-
-
Martinez-Quiles, N.1
-
34
-
-
0034654348
-
WIP a binding partner for Wiskott-Aldrich syndrome protein, cooperates with Vav in the regulation of T cell activation
-
Savoy DN, Billadeau DD, Leibson PJ. WIP, a binding partner for Wiskott-Aldrich syndrome protein, cooperates with Vav in the regulation of T cell activation. J Immunol 2000;164:2866-2870.
-
(2000)
J Immunol
, vol.164
, pp. 2866-2870
-
-
Savoy, D.N.1
Billadeau, D.D.2
Leibson, P.J.3
-
35
-
-
0036083157
-
WICH, a novel verprolin homology domain-containing protein that functions cooperatively with N-WASp in actin-microspike formation
-
Kato M, et al. WICH, a novel verprolin homology domain-containing protein that functions cooperatively with N-WASp in actin-microspike formation. Biochem Biophys Res Commun 2002;291:41-47.
-
(2002)
Biochem Biophys Res Commun
, vol.291
, pp. 41-47
-
-
Kato, M.1
-
36
-
-
0035949469
-
CR16 forms a complex with N-WASp in brain and is a novel member of a conserved proline-rich actin-binding protein family
-
Ho HY, Rohatgi R, Ma L, Kirschner MW. CR16 forms a complex with N-WASp in brain and is a novel member of a conserved proline-rich actin-binding protein family. Proc Natl Acad Sci USA 2001;98:11306-11311.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 11306-11311
-
-
Ho, H.Y.1
Rohatgi, R.2
Ma, L.3
Kirschner, M.W.4
-
37
-
-
0029680639
-
Two GTPases, Cdc42 and Rac, bind directly to a protein implicated in the immunodeficiency disorder Wiskott-Aldrich syndrome
-
Aspenstrom P, Lindberg U, Hall A. Two GTPases, Cdc42 and Rac, bind directly to a protein implicated in the immunodeficiency disorder Wiskott-Aldrich syndrome. Curr Biol 1996;6:70-75.
-
(1996)
Curr Biol
, vol.6
, pp. 70-75
-
-
Aspenstrom, P.1
Lindberg, U.2
Hall, A.3
-
38
-
-
0028786020
-
A conserved binding motif defines numerous candidate target proteins for both Cdc42 and Rac GTPases
-
Burbelo PD, Drechsel D, Hall A. A conserved binding motif defines numerous candidate target proteins for both Cdc42 and Rac GTPases. J Biol Chem 1995;270:29071-29074.
-
(1995)
J Biol Chem
, vol.270
, pp. 29071-29074
-
-
Burbelo, P.D.1
Drechsel, D.2
Hall, A.3
-
39
-
-
0032559362
-
Rho GTPases and the actin cytoskeleton
-
Hall A. Rho GTPases and the actin cytoskeleton. Science 1998;279:509-514.
-
(1998)
Science
, vol.279
, pp. 509-514
-
-
Hall, A.1
-
40
-
-
0030006284
-
Wiskott-Aldrich syndrome protein, a novel effector for the GTPase CDC42HS, is implicated in actin polymerization
-
Symons M, et al. Wiskott-Aldrich syndrome protein, a novel effector for the GTPase CDC42HS, is implicated in actin polymerization. Cell 1996;84:723-734.
-
(1996)
Cell
, vol.84
, pp. 723-734
-
-
Symons, M.1
-
41
-
-
0033578780
-
Wiskott-Aldrich syndrome protein induces actin clustering without direct binding to Cdc42
-
Kato M, et al. Wiskott-Aldrich syndrome protein induces actin clustering without direct binding to Cdc42. J Biol Chem 1999;274:27225-27230.
-
(1999)
J Biol Chem
, vol.274
, pp. 27225-27230
-
-
Kato, M.1
-
42
-
-
0033574722
-
The interaction between N-WASp and the Arp 2/3 complex links Cdc42-dependent signals to actin assembly
-
Rohatgi R, et al. The interaction between N-WASp and the Arp 2/3 complex links Cdc42-dependent signals to actin assembly. Cell 1999;97:221-231.
-
(1999)
Cell
, vol.97
, pp. 221-231
-
-
Rohatgi, R.1
-
43
-
-
0034721696
-
Integration of multiple signals through cooperative regulation of the N-WASp-Arp2/3 complex
-
Prehoda KE, Scott JA, Mullins RD, Lim WA. Integration of multiple signals through cooperative regulation of the N-WASp-Arp2/3 complex. Science 2000;290:801-806.
-
(2000)
Science
, vol.290
, pp. 801-806
-
-
Prehoda, K.E.1
Scott, J.A.2
Mullins, R.D.3
Lim, W.A.4
-
44
-
-
0034624753
-
Autoinhibition and activation mechanisms of the Wiskott-Aldrich syndrome protein
-
Kim AS, Kakalis LT, Abdul-Manan N, Liu GA, Rosen MK. Autoinhibition and activation mechanisms of the Wiskott-Aldrich syndrome protein. Nature 2000;404:151-158.
-
(2000)
Nature
, vol.404
, pp. 151-158
-
-
Kim, A.S.1
Kakalis, L.T.2
Abdul-Manan, N.3
Liu, G.A.4
Rosen, M.K.5
-
45
-
-
0035093787
-
Constitutively activating mutation in WASp causes X-linked severe congenital neutropenia
-
Devriendt K, et al. Constitutively activating mutation in WASp causes X-linked severe congenital neutropenia. Nat Genet 2001;27:313-317.
-
(2001)
Nat Genet
, vol.27
, pp. 313-317
-
-
Devriendt, K.1
-
46
-
-
0034877142
-
WASp recruitment to the T cell: APC contact site occurs independendy of Cdc42 activation
-
Cannon JL, et al. WASp recruitment to the T cell: APC contact site occurs independendy of Cdc42 activation. Immunity 2001;15:249-259.
-
(2001)
Immunity
, vol.15
, pp. 249-259
-
-
Cannon, J.L.1
-
47
-
-
0032541137
-
The Cdc42/Rac interactive binding region of the Wiskott-Aldrich syndrome protein (WASp) is necessary but not sufficient for tight binding to Cdc42 and structure formation
-
Rudolph MG, Bayer P, Abo A, Kuhlmann J, Vetter IR, Wittinghofer A. The Cdc42/Rac interactive binding region of the Wiskott-Aldrich syndrome protein (WASp) is necessary but not sufficient for tight binding to Cdc42 and structure formation. J Biol Chem 1998;273:18067-18076.
-
(1998)
J Biol Chem
, vol.273
, pp. 18067-18076
-
-
Rudolph, M.G.1
Bayer, P.2
Abo, A.3
Kuhlmann, J.4
Vetter, I.R.5
Wittinghofer, A.6
-
48
-
-
0034683746
-
Mechanisms of N-WASp activation by Cdc42 and phosphatidylinositol 4,5-bisphosphate
-
Rohatgi R, Ho HY, Kirschner MW. Mechanisms of N-WASp activation by Cdc42 and phosphatidylinositol 4,5-bisphosphate. J Cell Biol 2000;150:1299-1310.
-
(2000)
J Cell Biol
, vol.150
, pp. 1299-1310
-
-
Rohatgi, R.1
Ho, H.Y.2
Kirschner, M.W.3
-
49
-
-
0034683671
-
Activation by Cdc42 and PIP2 of Wiskott-Aldrich syndrome protein (WASp) stimulates actin nucleation by Arp 2/3 complex
-
Higgs HN, Pollard TD. Activation by Cdc42 and PIP2 of Wiskott-Aldrich syndrome protein (WASp) stimulates actin nucleation by Arp 2/3 complex. J Cell Biol 2000;150:1311-1320.
-
(2000)
J Cell Biol
, vol.150
, pp. 1311-1320
-
-
Higgs, H.N.1
Pollard, T.D.2
-
50
-
-
0029126878
-
Wiskott-Aldrich syndrome protein physically associates with Nck through Src homology 3 domains
-
Rivero-Lezcano OM, Marcilla A, Sameshima JH, Robbins KC. Wiskott-Aldrich syndrome protein physically associates with Nck through Src homology 3 domains. Mol Cell Biol 1995;15:5725-5731.
-
(1995)
Mol Cell Biol
, vol.15
, pp. 5725-5731
-
-
Rivero-Lezcano, O.M.1
Marcilla, A.2
Sameshima, J.H.3
Robbins, K.C.4
-
51
-
-
0030221475
-
Wiskott-Aldrich syndrome protein function (WASp) is a binding partner for c-Src family protein-tyrosine kinases
-
Banin S, Truong O, Katz DR, Waterfield MD, Bickell PM, Gout I. Wiskott-Aldrich syndrome protein function (WASp) is a binding partner for c-Src family protein-tyrosine kinases. Curr Biol 1996;6:981-988.
-
(1996)
Curr Biol
, vol.6
, pp. 981-988
-
-
Banin, S.1
Truong, O.2
Katz, D.R.3
Waterfield, M.D.4
Bickell, P.M.5
Gout, I.6
-
52
-
-
0031032251
-
Tyrosine kinase signaling regulates Wiskott-Aldrich syndrome protein function, which is essential for megakaryocyte differentiation
-
Miki H, Nonoyama S, Zhu Q, Aruffo A, Ochs HD, Takenawa T. Tyrosine kinase signaling regulates Wiskott-Aldrich syndrome protein function, which is essential for megakaryocyte differentiation. Cell Growth Differ 1997;8:195-202.
-
(1997)
Cell Growth Differ
, vol.8
, pp. 195-202
-
-
Miki, H.1
Nonoyama, S.2
Zhu, Q.3
Aruffo, A.4
Ochs, H.D.5
Takenawa, T.6
-
53
-
-
0033559321
-
Involvement of Wiskott-Aldrich syndrome protein in B-cell cytoplasmic tyrosine kinase pathway
-
Baba Y, et al. Involvement of Wiskott-Aldrich syndrome protein in B-cell cytoplasmic tyrosine kinase pathway. Blood 1999;93:2003-2012.
-
(1999)
Blood
, vol.93
, pp. 2003-2012
-
-
Baba, Y.1
-
54
-
-
0034677932
-
Cdc42-interacting protein 4 mediates binding of the Wiskott-Aldrich syndrome protein to microtubules
-
Tian L, Nelson DL, Stewart DM. Cdc42-interacting protein 4 mediates binding of the Wiskott-Aldrich syndrome protein to microtubules. J Biol Chem 2000;275:7854-7861.
-
(2000)
J Biol Chem
, vol.275
, pp. 7854-7861
-
-
Tian, L.1
Nelson, D.L.2
Stewart, D.M.3
-
55
-
-
0035353161
-
CrkL is an adapter for Wiskott-Aldrich syndrome protein and Syk
-
Oda A, et al. CrkL is an adapter for Wiskott-Aldrich syndrome protein and Syk. Blood 2001;97:2633-2639.
-
(2001)
Blood
, vol.97
, pp. 2633-2639
-
-
Oda, A.1
-
56
-
-
0035905308
-
The intersectin 2 adaptor links Wiskott-Aldrich syndrome protein (WASp)-mediated actin polymerization to T cell antigen receptor endocytosis
-
McGavin MKH, Badour K, Hardy LA, Kubiseski TJ, Zhang J, Siminovitch KA. The intersectin 2 adaptor links Wiskott-Aldrich syndrome protein (WASp)-mediated actin polymerization to T cell antigen receptor endocytosis. J Exp Med 2001;194:1777-1787.
-
(2001)
J Exp Med
, vol.194
, pp. 1777-1787
-
-
McGavin, M.K.H.1
Badour, K.2
Hardy, L.A.3
Kubiseski, T.J.4
Zhang, J.5
Siminovitch, K.A.6
-
57
-
-
0037241232
-
The Wiskott-Aldrich syndrome protein acts downstream of CD2 and the CD2AP and PSTPIP1 adaptors to promote formation of the immunological synapse
-
Badour K, et al. The Wiskott-Aldrich syndrome protein acts downstream of CD2 and the CD2AP and PSTPIP1 adaptors to promote formation of the immunological synapse. Immunity 2003;18:141-154.
-
(2003)
Immunity
, vol.18
, pp. 141-154
-
-
Badour, K.1
-
58
-
-
0030292702
-
Evidence that the Wiskott-Aldrich syndrome protein may be involved in lymphoid cell signaling pathways
-
Cory GO, et al. Evidence that the Wiskott-Aldrich syndrome protein may be involved in lymphoid cell signaling pathways. J Immunol 1996;157:3791-3795.
-
(1996)
J Immunol
, vol.157
, pp. 3791-3795
-
-
Cory, G.O.1
-
59
-
-
0030793720
-
Wiskott-Aldrich syndrome protein is associated with the adaptor Grb2 and the epidermal growth factor receptor in living cells
-
She HY, et al. Wiskott-Aldrich syndrome protein is associated with the adaptor Grb2 and the epidermal growth factor receptor in living cells. Mol Biol Cell 1997;8:1709-1721.
-
(1997)
Mol Biol Cell
, vol.8
, pp. 1709-1721
-
-
She, H.Y.1
-
60
-
-
0037084459
-
N-WASp activation by a β1-integrin-dependent mechanism supports P13K-independent chemotaxis stimulated by urokinase-type plasminogen activator
-
Sturge J, Hamelin J, Jones GE. N-WASp activation by a β1-integrin-dependent mechanism supports P13K-independent chemotaxis stimulated by urokinase-type plasminogen activator. J Cell Sci 2002;115:699-711.
-
(2002)
J Cell Sci
, vol.115
, pp. 699-711
-
-
Sturge, J.1
Hamelin, J.2
Jones, G.E.3
-
61
-
-
0035854732
-
Nck and phosphatidylinositol 4,5-biphosphate synergistically activate actm polymerization through the N-WASp-Arp 2/3 pathway
-
Rohatgi R, Nollau P, Ho HY, Kirschner MW, Mayer BJ. Nck and phosphatidylinositol 4,5-biphosphate synergistically activate actm polymerization through the N-WASp-Arp 2/3 pathway. J Biol Chem 2001;276:26448-26452.
-
(2001)
J Biol Chem
, vol.276
, pp. 26448-26452
-
-
Rohatgi, R.1
Nollau, P.2
Ho, H.Y.3
Kirschner, M.W.4
Mayer, B.J.5
-
62
-
-
0034698158
-
Grb2 links signaling to actin assembly by enhancing interaction of neural Wiskott-Aldrich syndrome protein (N-WASp) with actin-related protein (Arp 2/3) complex
-
Carlier MF, et al. Grb2 links signaling to actin assembly by enhancing interaction of neural Wiskott-Aldrich syndrome protein (N-WASp) with actin-related protein (Arp 2/3) complex. J Biol Chem 2000;275:21946-21952.
-
(2000)
J Biol Chem
, vol.275
, pp. 21946-21952
-
-
Carlier, M.F.1
-
63
-
-
0035809163
-
A novel neutral Wiskott-Aldrich syndrome protein (N-WASp) binding protein, WISH, induces Arp 2/3 complex activation independent of Cdc42
-
Fukuoka M, Suetsugu S, Miki H, Fukami K, Endo T, Takenawa T. A novel neutral Wiskott-Aldrich syndrome protein (N-WASp) binding protein, WISH, induces Arp 2/3 complex activation independent of Cdc42. J Cell Biol 2001;152:471-482.
-
(2001)
J Cell Biol
, vol.152
, pp. 471-482
-
-
Fukuoka, M.1
Suetsugu, S.2
Miki, H.3
Fukami, K.4
Endo, T.5
Takenawa, T.6
-
64
-
-
0032538888
-
The essential role of profilin in the assembly of actin for microspike formation
-
Suetsugu S, Miki H, Takenawa T. The essential role of profilin in the assembly of actin for microspike formation. EMBO J 1998;17:6516-6526.
-
(1998)
EMBO J
, vol.17
, pp. 6516-6526
-
-
Suetsugu, S.1
Miki, H.2
Takenawa, T.3
-
65
-
-
0034605099
-
Profilin enhances Cdc42-induced nucleation of actin polymerization
-
Yang C, et al. Profilin enhances Cdc42-induced nucleation of actin polymerization. J Cell Biol 2000;150:1001-1012.
-
(2000)
J Cell Biol
, vol.150
, pp. 1001-1012
-
-
Yang, C.1
-
66
-
-
0034666134
-
Profilin is required for sustaining efficient intra- and intercellular spreading of Shigella flexneri
-
Mimuro H, Suzuki T, Suetsugu S, Miki H, Takenawa T, Sasakawa C. Profilin is required for sustaining efficient intra- and intercellular spreading of Shigella flexneri. J Biol Chem 2000;275:28893-28901.
-
(2000)
J Biol Chem
, vol.275
, pp. 28893-28901
-
-
Mimuro, H.1
Suzuki, T.2
Suetsugu, S.3
Miki, H.4
Takenawa, T.5
Sasakawa, C.6
-
67
-
-
0030000795
-
Identification of regions of the Wiskott-Aldrich syndrome protein responsible for association with selected Src homology 3 domains
-
Finan PM, et al. Identification of regions of the Wiskott-Aldrich syndrome protein responsible for association with selected Src homology 3 domains. J Biol Chem 1996;271:226291-226295.
-
(1996)
J Biol Chem
, vol.271
, pp. 226291-226295
-
-
Finan, P.M.1
-
68
-
-
0037008772
-
Idenufication of novel SH3 domain ligands for the Src family kinase Hck. Wiskott-Aldrich syndrome protein (WASp), WASp-interacting protein (WIP), and ELMO1
-
Scott MP, Zappacosta F, Kim EY, Annan RS, Miller WT. Idenufication of novel SH3 domain ligands for the Src family kinase Hck. Wiskott-Aldrich syndrome protein (WASp), WASp-interacting protein (WIP), and ELMO1. J Biol Chem 2002;277:28238-28246.
-
(2002)
J Biol Chem
, vol.277
, pp. 28238-28246
-
-
Scott, M.P.1
Zappacosta, F.2
Kim, E.Y.3
Annan, R.S.4
Miller, W.T.5
-
69
-
-
0033230229
-
Antigen receptor-induced activation and cytoskeletal rearrangement are impaired in Wiskott-Aldrich syndrome protein-deficient lymphocytes
-
Zhang J, et al. Antigen receptor-induced activation and cytoskeletal rearrangement are impaired in Wiskott-Aldrich syndrome protein-deficient lymphocytes. J Exp Med 1999;190:1329-1341.
-
(1999)
J Exp Med
, vol.190
, pp. 1329-1341
-
-
Zhang, J.1
-
70
-
-
0033213484
-
Impaired NFATc translocation and failure of Th2 development in Itk-deficient CD4+ T cells
-
Fowell DJ, et al. Impaired NFATc translocation and failure of Th2 development in Itk-deficient CD4+ T cells. Immunity 1999;11:399-409.
-
(1999)
Immunity
, vol.11
, pp. 399-409
-
-
Fowell, D.J.1
-
71
-
-
0034619847
-
IRSp53 is an essential intermediate between Rac and WAVE in the regulation of membrane ruffling
-
Miki H, Yamaguchi H, Suetsugu S, Takenawa T. IRSp53 is an essential intermediate between Rac and WAVE in the regulation of membrane ruffling. Nature 2000;408:732-735.
-
(2000)
Nature
, vol.408
, pp. 732-735
-
-
Miki, H.1
Yamaguchi, H.2
Suetsugu, S.3
Takenawa, T.4
-
72
-
-
0035887313
-
A WASp-VASp complex regulates actin polymerization at the plasma membrane
-
Castellano F, Le Clainche C, Patin D, Carlier MF, Chavrier P. A WASp-VASp complex regulates actin polymerization at the plasma membrane. EMBO J 2001;20:5603-5614.
-
(2001)
EMBO J
, vol.20
, pp. 5603-5614
-
-
Castellano, F.1
Le Clainche, C.2
Patin, D.3
Carlier, M.F.4
Chavrier, P.5
-
73
-
-
0032585538
-
Scar1 and the related Wiskott-Aldrich syndrome protein WASp regulate the actin cytoskdeton through the Arp 2/3 complex
-
Machesky LM, Insall RH. Scar1 and the related Wiskott-Aldrich syndrome protein WASp regulate the actin cytoskdeton through the Arp 2/3 complex. Curr Biol 1998;8:1347-1356.
-
(1998)
Curr Biol
, vol.8
, pp. 1347-1356
-
-
Machesky, L.M.1
Insall, R.H.2
-
74
-
-
0037138384
-
WH2 domain: A small, versatile adaptor for actin monomers
-
Paunola E, Mattla PK, Lappalainen P. WH2 domain: a small, versatile adaptor for actin monomers. FEBS Lett 2002;513:92-97.
-
(2002)
FEBS Lett
, vol.513
, pp. 92-97
-
-
Paunola, E.1
Mattla, P.K.2
Lappalainen, P.3
-
75
-
-
0032568650
-
The interaction of Arp 2/3 complex with actin: Nucleation, high affinity pointed end capping, and formation of branching networks of filaments
-
Mullins RD, Heuser JA, Pollard TD. The interaction of Arp 2/3 complex with actin: nucleation, high affinity pointed end capping, and formation of branching networks of filaments. Proc Natl Acad Sci USA 1998;95:6181-6186.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 6181-6186
-
-
Mullins, R.D.1
Heuser, J.A.2
Pollard, T.D.3
-
76
-
-
0035146636
-
Interaction of WASp/SCAR proteins with actin and vertebrate Arp 2/3 complex
-
Mazchand JB, Kaiser DA, Pollard JD, Higgs HN. Interaction of WASp/SCAR proteins with actin and vertebrate Arp 2/3 complex. Nat Cell Biol 2001;3:76-82.
-
(2001)
Nat Cell Biol
, vol.3
, pp. 76-82
-
-
Mazchand, J.B.1
Kaiser, D.A.2
Pollard, J.D.3
Higgs, H.N.4
-
77
-
-
0242558357
-
The verprolin-like central (VC) region of Wiskott-Aldrich syndrome protein induces Arp 2/3 complex-dependent actin nucleation
-
Hüfner K, Higgs HN, Pollard TD, Jacobi C, Aepfelbacher M, Linder S. The verprolin-like central (VC) region of Wiskott-Aldrich syndrome protein induces Arp 2/3 complex-dependent actin nucleation. J Biol Chem 2001;276:35761-35767.
-
(2001)
J Biol Chem
, vol.276
, pp. 35761-35767
-
-
Hüfner, K.1
Higgs, H.N.2
Pollard, T.D.3
Jacobi, C.4
Aepfelbacher, M.5
Linder, S.6
-
78
-
-
0033616763
-
Scar, a WASp-related protein, acuvates nucleation of actin filaments by the Arp 2/3 complex
-
Machesky LM, et al. Scar, a WASp-related protein, acuvates nucleation of actin filaments by the Arp 2/3 complex. Proc Natl Acad Sci USA 1999;96:3739-3744.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 3739-3744
-
-
Machesky, L.M.1
-
79
-
-
0033587188
-
The Wiskott-Aldrich syndrome protein directs actin-based motility by stimulating actin nucleation with the Arp 2/3 complex
-
Yarar D, To W, Abo A, Welch MD. The Wiskott-Aldrich syndrome protein directs actin-based motility by stimulating actin nucleation with the Arp 2/3 complex. Curr Biol 1999;9:555-558.
-
(1999)
Curr Biol
, vol.9
, pp. 555-558
-
-
Yarar, D.1
To, W.2
Abo, A.3
Welch, M.D.4
-
80
-
-
0033576288
-
Influence of the C terminus of Wiskott-Aldrich syndrome protein (WASp) and the Arp 2/3 complex on actin polymerization
-
Higgs HN, Blanchoin L, Pollard TD. Influence of the C terminus of Wiskott-Aldrich syndrome protein (WASp) and the Arp 2/3 complex on actin polymerization. Biochemistry 1999;38:15212-15222.
-
(1999)
Biochemistry
, vol.38
, pp. 15212-15222
-
-
Higgs, H.N.1
Blanchoin, L.2
Pollard, T.D.3
-
81
-
-
0035861670
-
Activation of Arp 2/3 complex by Wiskott-Aldrich syndrome protein is linked to enhanced binding of ATP to Arp2
-
Le Clainche C, Didry D, Carlier MF, Pantaloni D. Activation of Arp 2/3 complex by Wiskott-Aldrich syndrome protein is linked to enhanced binding of ATP to Arp2. J Biol Chem 2001;276:46689-46692.
-
(2001)
J Biol Chem
, vol.276
, pp. 46689-46692
-
-
Le Clainche, C.1
Didry, D.2
Carlier, M.F.3
Pantaloni, D.4
-
82
-
-
0034687235
-
Interactions of ADF/cofilin, Arp 2/3 complex, capping protein and profilin in remodeling of branched actin filament networks
-
Blanchoin L, Pollard TD, Mullins RD. Interactions of ADF/cofilin, Arp 2/3 complex, capping protein and profilin in remodeling of branched actin filament networks. Curr Biol 2000;10:1273-1282.
-
(2000)
Curr Biol
, vol.10
, pp. 1273-1282
-
-
Blanchoin, L.1
Pollard, T.D.2
Mullins, R.D.3
-
83
-
-
0033609388
-
Structure of Cdc42 in complex with the GTPase-binding domain of the Wiskott-Aldrich syndrome protein
-
Abdul-Manan N, et al. Structure of Cdc42 in complex with the GTPase-binding domain of the Wiskott-Aldrich syndrome protein. Nature 1999;399:379-383.
-
(1999)
Nature
, vol.399
, pp. 379-383
-
-
Abdul-Manan, N.1
-
84
-
-
0037160142
-
Phosphorylation of tyrosine 291 enhances the ability of WASp to stimulate actin polymerization and filopodium formation
-
Cory GO, Garg R, Cramer R, Ridley AJ. Phosphorylation of tyrosine 291 enhances the ability of WASp to stimulate actin polymerization and filopodium formation. J Biol Chem 2002;177:45115-45121.
-
(2002)
J Biol Chem
, vol.177
, pp. 45115-45121
-
-
Cory, G.O.1
Garg, R.2
Cramer, R.3
Ridley, A.J.4
-
85
-
-
0037169501
-
PSTPIP is a substrate of PTP-PEST and serves as a scaffold guiding PTP-PEST toward a specific dephosphorylation of WASP
-
Cote JF, et al. PSTPIP is a substrate of PTP-PEST and serves as a scaffold guiding PTP-PEST toward a specific dephosphorylation of WASP. J Biol Chem 2002;277:2973-2986.
-
(2002)
J Biol Chem
, vol.277
, pp. 2973-2986
-
-
Cote, J.F.1
-
86
-
-
0018834588
-
The Wiskott-Aldrich syndrome: Studies of lymphocytes, granulocytes and platelets
-
Ochs HD, Slichter SJ, Harker LA, Von Behrens WE, Clark RA, Wedgwood RJ. The Wiskott-Aldrich syndrome: studies of lymphocytes, granulocytes and platelets. Blood 1980;55:243-252.
-
(1980)
Blood
, vol.55
, pp. 243-252
-
-
Ochs, H.D.1
Slichter, S.J.2
Harker, L.A.3
Von Behrens, W.E.4
Clark, R.A.5
Wedgwood, R.J.6
-
87
-
-
0014772251
-
Defective lymphocyte transformation and delayed hypersensitivity in Wiskott-Aldrich syndrome
-
Oppenheim JJ, Blaese RM, Waldmann TA. Defective lymphocyte transformation and delayed hypersensitivity in Wiskott-Aldrich syndrome. J Immunol 1970;104:835-844.
-
(1970)
J Immunol
, vol.104
, pp. 835-844
-
-
Oppenheim, J.J.1
Blaese, R.M.2
Waldmann, T.A.3
-
88
-
-
0027444915
-
T cells of patients with the Wiskott-Aldrich syndrome have a restricted defect in proliferative response
-
Molina IJ, Sancho J, Terhorst C, Rosen FC, Remold O'Donnell E. T cells of patients with the Wiskott-Aldrich syndrome have a restricted defect in proliferative response. J Immunol 1993;151:4383-4390.
-
(1993)
J Immunol
, vol.151
, pp. 4383-4390
-
-
Molina, I.J.1
Sancho, J.2
Terhorst, C.3
Rosen, F.C.4
Remold O'Donnell, E.5
-
89
-
-
0029286835
-
A diagnostic assay for the Wiskott-Aldrich syndrome and its variant forms
-
Siminovitch KA, Greer WL, Novogrodsky A, Axelsson B, Somani AK, Peacocke M. A diagnostic assay for the Wiskott-Aldrich syndrome and its variant forms. J Invest Med 1995;43:159-169.
-
(1995)
J Invest Med
, vol.43
, pp. 159-169
-
-
Siminovitch, K.A.1
Greer, W.L.2
Novogrodsky, A.3
Axelsson, B.4
Somani, A.K.5
Peacocke, M.6
-
90
-
-
0032118427
-
Wiskott-Aldrich syndrome protein-deficient mice reveal a role for WASp in T but not B cell activation
-
Snapper SB, et al. Wiskott-Aldrich syndrome protein-deficient mice reveal a role for WASp in T but not B cell activation. Immunity 1998;9:81-90.
-
(1998)
Immunity
, vol.9
, pp. 81-90
-
-
Snapper, S.B.1
-
91
-
-
0033925403
-
Impaired interleukin-2 production in T cells from a patient with Wiskott-Aldrich syndrome: Basis of clinical effect of interleukin-2 replacement therapy
-
Azuma H, et al. Impaired interleukin-2 production in T cells from a patient with Wiskott-Aldrich syndrome: basis of clinical effect of interleukin-2 replacement therapy. Eur J Pediatr 2000;159:633-634.
-
(2000)
Eur J Pediatr
, vol.159
, pp. 633-634
-
-
Azuma, H.1
-
92
-
-
0037133297
-
WASp verprolin homology, cofilin homology, and acidic region domain-mediated actin polymerization is required for T cell development
-
Zhang J, Shi F, Badour K, Deng Y, McGavin MK, Siminovitch KA. WASp verprolin homology, cofilin homology, and acidic region domain-mediated actin polymerization is required for T cell development. Proc Natl Acad Sci USA 2002;99:2240-2245.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 2240-2245
-
-
Zhang, J.1
Shi, F.2
Badour, K.3
Deng, Y.4
McGavin, M.K.5
Siminovitch, K.A.6
-
93
-
-
0024359027
-
Altered expression of leukocyte sialoglycoprotein in Wiskott-Aldrich syndrome is associated with a specific defect in O-glycosylation
-
Greer WL, et al. Altered expression of leukocyte sialoglycoprotein in Wiskott-Aldrich syndrome is associated with a specific defect in O-glycosylation. Biochem Cell Biol 1989;67:503-509.
-
(1989)
Biochem Cell Biol
, vol.67
, pp. 503-509
-
-
Greer, W.L.1
-
94
-
-
0033136717
-
Deficient T cell fate specification in mice with an induced inactivation of Notch1
-
Radtke F, et al. Deficient T cell fate specification in mice with an induced inactivation of Notch1. Immunity 1999;10:547-558.
-
(1999)
Immunity
, vol.10
, pp. 547-558
-
-
Radtke, F.1
-
95
-
-
0030297895
-
An activated form of Notch influences the choice between CD4 and CD8 T cell lineages
-
Robey E, et al. An activated form of Notch influences the choice between CD4 and CD8 T cell lineages. Cell 1996;87:483-492.
-
(1996)
Cell
, vol.87
, pp. 483-492
-
-
Robey, E.1
-
96
-
-
0032516877
-
The Wiskott-Aldrich syndrome protein-interacting protein (WIP) binds to the adaptor protein Nck
-
Anton IM, Lu W, Mayer BJ, Ramesh N, Geha RS. The Wiskott-Aldrich syndrome protein-interacting protein (WIP) binds to the adaptor protein Nck. J Biol Chem 1998;273:20992-20995.
-
(1998)
J Biol Chem
, vol.273
, pp. 20992-20995
-
-
Anton, I.M.1
Lu, W.2
Mayer, B.J.3
Ramesh, N.4
Geha, R.S.5
-
97
-
-
0034599541
-
Fyn-binding protein (Fyb)/SLP-76-associated protein (SLAP), Ena/vasodilator-stimulated phosphoprotein (VASP) proteins and the Arp 2/3 complex link T cell receptor (TCR) signaling to the actin cytoskeleton
-
Krause M, Sechi AS, Konradt M, Monner D, Gertler FB, Wehland J. Fyn-binding protein (Fyb)/SLP-76-associated protein (SLAP), Ena/vasodilator-stimulated phosphoprotein (VASP) proteins and the Arp 2/3 complex link T cell receptor (TCR) signaling to the actin cytoskeleton. J Cell Biol 2000;149:181-194.
-
(2000)
J Cell Biol
, vol.149
, pp. 181-194
-
-
Krause, M.1
Sechi, A.S.2
Konradt, M.3
Monner, D.4
Gertler, F.B.5
Wehland, J.6
-
98
-
-
0035211279
-
Evidence for a molecular complex consisting of Fyb/SLAP, SLP-76, Nck, VASP and WASp that links the actin cytoskeleton to Fcγ receptor signaling during phagocytosis
-
Coppolino MG, et al. Evidence for a molecular complex consisting of Fyb/SLAP, SLP-76, Nck, VASP and WASp that links the actin cytoskeleton to Fcγ receptor signaling during phagocytosis. J Cell Sci 2001;114:4307-4318.
-
(2001)
J Cell Sci
, vol.114
, pp. 4307-4318
-
-
Coppolino, M.G.1
-
99
-
-
0020058757
-
The area of attachment of cytotoxic T lymphocytes to their target cells shows high motility and polarization of actin, but not myosin
-
Ryser JE, Rungger-Brandle E, Chaponnier C, Gabbiani G, Vassalli P. The area of attachment of cytotoxic T lymphocytes to their target cells shows high motility and polarization of actin, but not myosin. J Immunol 1982;128:1159-1162.
-
(1982)
J Immunol
, vol.128
, pp. 1159-1162
-
-
Ryser, J.E.1
Rungger-Brandle, E.2
Chaponnier, C.3
Gabbiani, G.4
Vassalli, P.5
-
100
-
-
0028961573
-
A sustained signaling leading to T cell activation results from prolonged T cell receptor occupancy. Role of T cell actin cytoskeleton
-
Valitutti S, Dessing M, Aktories K, Gallati H, Lanzavecchia A. A sustained signaling leading to T cell activation results from prolonged T cell receptor occupancy. Role of T cell actin cytoskeleton. J Exp Med 1995;181:577-584.
-
(1995)
J Exp Med
, vol.181
, pp. 577-584
-
-
Valitutti, S.1
Dessing, M.2
Aktories, K.3
Gallati, H.4
Lanzavecchia, A.5
-
101
-
-
0031936042
-
+ T cells: Compulsory cytoskeletal alterations for the triggering of an intracellular calcium response
-
+ T cells: compulsory cytoskeletal alterations for the triggering of an intracellular calcium response. Eur J Immunol 1998;28:716-729.
-
(1998)
Eur J Immunol
, vol.28
, pp. 716-729
-
-
Delon, J.1
Bercovici, N.2
Liblau, R.3
Trautmann, A.4
-
102
-
-
0033538574
-
The immunological synapse: A molecular machine controlling T cell activation
-
Grakoui A, et al. The immunological synapse: a molecular machine controlling T cell activation. Science 1999;285:221-227.
-
(1999)
Science
, vol.285
, pp. 221-227
-
-
Grakoui, A.1
-
103
-
-
0037154747
-
T cell receptor signaling precedes immunological synapse formation
-
Lee KH, Holdorf AD, Dustin ML, Chan AC, Allen PM, Shaw AS. T cell receptor signaling precedes immunological synapse formation. Science 2002;295:1539-1542.
-
(2002)
Science
, vol.295
, pp. 1539-1542
-
-
Lee, K.H.1
Holdorf, A.D.2
Dustin, M.L.3
Chan, A.C.4
Allen, P.M.5
Shaw, A.S.6
-
104
-
-
0028354216
-
Small splenic B cells that bind to antigen specific T helper (Th) cells and face the site of cytokine production in the Th cells selectively proliferate: Immunofluorescence microscopic studies of Th-B antigen-presenting cell interactions
-
Kupfer H, Monks CR, Kupfer A. Small splenic B cells that bind to antigen specific T helper (Th) cells and face the site of cytokine production in the Th cells selectively proliferate: immunofluorescence microscopic studies of Th-B antigen-presenting cell interactions. J Exp Med 1994;179:1507-1515.
-
(1994)
J Exp Med
, vol.179
, pp. 1507-1515
-
-
Kupfer, H.1
Monks, C.R.2
Kupfer, A.3
-
105
-
-
0028179006
-
Lymphocyte responses and cytokines
-
Paul WE, Seder RA. Lymphocyte responses and cytokines. Cell 1994;76:241-251.
-
(1994)
Cell
, vol.76
, pp. 241-251
-
-
Paul, W.E.1
Seder, R.A.2
-
106
-
-
0030872948
-
PSTPIP: A tyrosine phosphorylated cleavage furrow-associated protein that is a substrate for a PEST tyrosine phosphatase
-
Spencer S, et al. PSTPIP: a tyrosine phosphorylated cleavage furrow-associated protein that is a substrate for a PEST tyrosine phosphatase. J Cell Biol 1997;138:845-860.
-
(1997)
J Cell Biol
, vol.138
, pp. 845-860
-
-
Spencer, S.1
-
107
-
-
0032535449
-
A cdc15-like adaptor protein (CD2BP1) interacts with the CD2 cytoplasmic domain and regulates CD2-triggered adhesion
-
Li J, et al. A cdc15-like adaptor protein (CD2BP1) interacts with the CD2 cytoplasmic domain and regulates CD2-triggered adhesion. EMBO J 1998;17:7320-7336.
-
(1998)
EMBO J
, vol.17
, pp. 7320-7336
-
-
Li, J.1
-
108
-
-
0032483559
-
A novel adaptor protein orchestrates receptor patterning and cytoskeletal polarity in T cell contact
-
Dustin ML, et al. A novel adaptor protein orchestrates receptor patterning and cytoskeletal polarity in T cell contact. Cell 1998;94:667-677.
-
(1998)
Cell
, vol.94
, pp. 667-677
-
-
Dustin, M.L.1
-
109
-
-
0030679644
-
Low affinity interaction of human or rat T cell adhesion molecule CD2 with ligands aligns adhering membrane to achieve high physiological affinity
-
Dustin ML, et al. Low affinity interaction of human or rat T cell adhesion molecule CD2 with ligands aligns adhering membrane to achieve high physiological affinity. J Biol Chem 1997;272:30889-30898.
-
(1997)
J Biol Chem
, vol.272
, pp. 30889-30898
-
-
Dustin, M.L.1
-
110
-
-
0029140842
-
Topology of the CD2-CD48 cell-adhesion molecule complex: Implications for antigen recognition by T cells
-
van der Merwe PA, McNamee PN, Davies EA, Barclay AN, Davies SJ. Topology of the CD2-CD48 cell-adhesion molecule complex: implications for antigen recognition by T cells. Curr Biol 1995;5:74-84.
-
(1995)
Curr Biol
, vol.5
, pp. 74-84
-
-
Van Der Merwe, P.A.1
McNamee, P.N.2
Davies, E.A.3
Barclay, A.N.4
Davies, S.J.5
-
111
-
-
0242683360
-
Leukocyte polarization in cell migration and immune interactions
-
Sanchez-Madrid F, del Pozo MA. Leukocyte polarization in cell migration and immune interactions. EMBO J 1999;18:501-511.
-
(1999)
EMBO J
, vol.18
, pp. 501-511
-
-
Sanchez-Madrid, F.1
Del Pozo, M.A.2
-
112
-
-
0023266351
-
The specific direct interaction of helper T cells and antigen-presenting B cells. II. Reorientation of the microtubule organizing centre andreorganization of the membrane-associated cytoskeleton inside the bound helper T cell
-
Kupfer A, Swain SL, Singer SJ. The specific direct interaction of helper T cells and antigen-presenting B cells. II. Reorientation of the microtubule organizing centre andreorganization of the membrane-associated cytoskeleton inside the bound helper T cell. J Exp Med 1987;165:1565-1580.
-
(1987)
J Exp Med
, vol.165
, pp. 1565-1580
-
-
Kupfer, A.1
Swain, S.L.2
Singer, S.J.3
-
113
-
-
0029008280
-
Regulation of the polarization of T cells toward antigen-presenting cells by Ras-related GTPase cdc42
-
Stowers L, Yelon D, Berg LJ, Chant J. Regulation of the polarization of T cells toward antigen-presenting cells by Ras-related GTPase cdc42. Proc Natl Acad Sci USA 1995;92:5027-5031.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 5027-5031
-
-
Stowers, L.1
Yelon, D.2
Berg, L.J.3
Chant, J.4
-
114
-
-
0032572528
-
Regulation of cell polarity by microtubules in fission yeast
-
Sawin KE, Nurse P. Regulation of cell polarity by microtubules in fission yeast. J Cell Biol 1998;142:457-471.
-
(1998)
J Cell Biol
, vol.142
, pp. 457-471
-
-
Sawin, K.E.1
Nurse, P.2
-
115
-
-
0036201054
-
Regulation of protein transport from the Golgi complex to the endoplasmic reticulum by Cdc42 and N-WASp
-
Luna A, et al. Regulation of protein transport from the Golgi complex to the endoplasmic reticulum by Cdc42 and N-WASp. Mol Biol Cell 2002;13:866-879.
-
(2002)
Mol Biol Cell
, vol.13
, pp. 866-879
-
-
Luna, A.1
-
116
-
-
0037088615
-
Drosophila Ack targets its substrate, the sorting nexin DSH3PX1, to a protein complex involved in axonal guidance
-
Worby CA, Simonson-Leff N, Clemens JC, Huddler D Jr, Muda M, Dixon JE. Drosophila Ack targets its substrate, the sorting nexin DSH3PX1, to a protein complex involved in axonal guidance. J Biol Chem 2002;277:9422-9428.
-
(2002)
J Biol Chem
, vol.277
, pp. 9422-9428
-
-
Worby, C.A.1
Simonson-Leff, N.2
Clemens, J.C.3
Huddler D., Jr.4
Muda, M.5
Dixon, J.E.6
-
117
-
-
0023256274
-
Endocytosis and recycling of the T3-T cell receptor complex. The role of T3 phosphorylation
-
Krangel M. Endocytosis and recycling of the T3-T cell receptor complex. The role of T3 phosphorylation. J Exp Med 1987;165:1141-1159.
-
(1987)
J Exp Med
, vol.165
, pp. 1141-1159
-
-
Krangel, M.1
-
118
-
-
0023202024
-
Internalization of human T lymphocyte receptors
-
Telerman A, Amson RB, Romasco F, Wybran J, Galand P, Mosselmans R. Internalization of human T lymphocyte receptors. Eur J Immunol 1987;17:991-997.
-
(1987)
Eur J Immunol
, vol.17
, pp. 991-997
-
-
Telerman, A.1
Amson, R.B.2
Romasco, F.3
Wybran, J.4
Galand, P.5
Mosselmans, R.6
-
119
-
-
0029797674
-
Signal extinction and T cell repolarization in T helper cell-antigen-presenting cell conjugates
-
Valitutti S, Muller S, Dessing M, Lanzavecchia A. Signal extinction and T cell repolarization in T helper cell-antigen-presenting cell conjugates. Eur J Immunol 1996;26:2012-2016.
-
(1996)
Eur J Immunol
, vol.26
, pp. 2012-2016
-
-
Valitutti, S.1
Muller, S.2
Dessing, M.3
Lanzavecchia, A.4
-
120
-
-
0033615606
-
TCR-mediated internalization of peptide-MHC complexes acquired by T cells
-
Huang JF, et al. TCR-mediated internalization of peptide-MHC complexes acquired by T cells. Science 1999;286:952-954.
-
(1999)
Science
, vol.286
, pp. 952-954
-
-
Huang, J.F.1
-
121
-
-
0033106167
-
The EH and SH3 domain Ese proteins regulate endocytosis by linking to dynamin and Eps15
-
Sengar AS, Wang W, Bishay J, Cohen S, Egan SE. The EH and SH3 domain Ese proteins regulate endocytosis by linking to dynamin and Eps15. EMBO J 1999;18:1159-1171.
-
(1999)
EMBO J
, vol.18
, pp. 1159-1171
-
-
Sengar, A.S.1
Wang, W.2
Bishay, J.3
Cohen, S.4
Egan, S.E.5
-
122
-
-
0032983521
-
Splice variants of intersectin are components of the endocytic machinery in neurons and nonneuronal cells
-
Hussain NK, et al. Splice variants of intersectin are components of the endocytic machinery in neurons and nonneuronal cells. J Biol Chem 1999;274:15671-15677.
-
(1999)
J Biol Chem
, vol.274
, pp. 15671-15677
-
-
Hussain, N.K.1
-
123
-
-
0034726027
-
Intersectin 2, a new multimodular protein involved in clathrin-mediated endocytosis
-
Pucharcos C, Estivill X, de la Luna S. Intersectin 2, a new multimodular protein involved in clathrin-mediated endocytosis. FEBS Lett 2000;478:43-51.
-
(2000)
FEBS Lett
, vol.478
, pp. 43-51
-
-
Pucharcos, C.1
Estivill, X.2
De La Luna, S.3
-
124
-
-
0030476867
-
Actin-, myosin-, and ubiquitin-dependent endocytosis
-
Riezman H, Munn A, Geli MI, Hicke L. Actin-, myosin-, and ubiquitin-dependent endocytosis. Experientia 1996;52:1033-1041.
-
(1996)
Experientia
, vol.52
, pp. 1033-1041
-
-
Riezman, H.1
Munn, A.2
Geli, M.I.3
Hicke, L.4
-
125
-
-
0037112944
-
Syndapins integrate N-WASp in receptor-mediated endocytosis
-
Kessels MM, Qualmann B. Syndapins integrate N-WASp in receptor-mediated endocytosis. EMBO J 2002;21:6083-6094.
-
(2002)
EMBO J
, vol.21
, pp. 6083-6094
-
-
Kessels, M.M.1
Qualmann, B.2
-
126
-
-
0031975838
-
Essential role for G protein-coupled receptor endocytosis in the activation of mitogen-activated protein kinase
-
Daaka Y, et al. Essential role for G protein-coupled receptor endocytosis in the activation of mitogen-activated protein kinase. J Biol Chem 1998;273:685-688.
-
(1998)
J Biol Chem
, vol.273
, pp. 685-688
-
-
Daaka, Y.1
-
127
-
-
0034282927
-
Intersectin, an adaptor protein involved in clathrin-mediated endocytosis, activates mitogenic signaling pathways
-
Adams A, Thorn JM, Yamabhai M, Kay BK, O'Bryan JP. Intersectin, an adaptor protein involved in clathrin-mediated endocytosis, activates mitogenic signaling pathways. J Biol Chem 2000;275:27414-27420.
-
(2000)
J Biol Chem
, vol.275
, pp. 27414-27420
-
-
Adams, A.1
Thorn, J.M.2
Yamabhai, M.3
Kay, B.K.4
O'Bryan, J.P.5
-
128
-
-
0034192223
-
Wiskott-Aldrich syndrome protein is necessary for efficient IgG-mediated phagocytosis
-
Lorenzi R, Brickell PM, Katz DR, Kinnon C, Thrasher AJ. Wiskott-Aldrich syndrome protein is necessary for efficient IgG-mediated phagocytosis. Blood 2000;95:2943-2946.
-
(2000)
Blood
, vol.95
, pp. 2943-2946
-
-
Lorenzi, R.1
Brickell, P.M.2
Katz, D.R.3
Kinnon, C.4
Thrasher, A.J.5
-
129
-
-
0032528414
-
Monocytes from Wiskott-Aldrich patients display reduced chemotaxis and lack of cell polarization in response to monocyte chemoattractant protein-1 and formyl-methionyl-leucyl-phenylalanine
-
Badolato R, et al. Monocytes from Wiskott-Aldrich patients display reduced chemotaxis and lack of cell polarization in response to monocyte chemoattractant protein-1 and formyl-methionyl-leucyl-phenylalanine. J Immunol 1998;161:1026-1033.
-
(1998)
J Immunol
, vol.161
, pp. 1026-1033
-
-
Badolato, R.1
-
130
-
-
0031831252
-
Chemotaxis of macrophages is abolished in the Wiskott-Aldrich syndrome
-
Zicha D, et al. Chemotaxis of macrophages is abolished in the Wiskott-Aldrich syndrome. Br J Haematol 1998;101:659-665.
-
(1998)
Br J Haematol
, vol.101
, pp. 659-665
-
-
Zicha, D.1
-
131
-
-
0034234559
-
The polarization defect of Wiskott-Aldrich syndrome macrophages is linked to dislocalization of the Arp2/3 complex
-
Linder S, Higgs H, Hufner K, Schwarz K, Pannicke U, Aepfelbacher M. The polarization defect of Wiskott-Aldrich syndrome macrophages is linked to dislocalization of the Arp2/3 complex. J Immimol 2000;165:221-225.
-
(2000)
J Immimol
, vol.165
, pp. 221-225
-
-
Linder, S.1
Higgs, H.2
Hufner, K.3
Schwarz, K.4
Pannicke, U.5
Aepfelbacher, M.6
-
132
-
-
0035883040
-
Configuration of human dendritic cell cytoskeleton by Pho GTPases, the WAS protein, and differentiation
-
Burns S, Thrasher AJ, Blundell MP, Machesky L, Jones GE. Configuration of human dendritic cell cytoskeleton by Pho GTPases, the WAS protein, and differentiation. Blood 2001;98:1142-1149.
-
(2001)
Blood
, vol.98
, pp. 1142-1149
-
-
Burns, S.1
Thrasher, A.J.2
Blundell, M.P.3
Machesky, L.4
Jones, G.E.5
-
133
-
-
0031689093
-
Intrinsic dendritic cell abnormalities in Wiskott-Aldrich syndrome
-
Binks M, Jones GE, Brickell PM, Kinnon C, Katz DR, Thrasher AJ. Intrinsic dendritic cell abnormalities in Wiskott-Aldrich syndrome. Eur J Immimol 1998;28:3259-3267.
-
(1998)
Eur J Immimol
, vol.28
, pp. 3259-3267
-
-
Binks, M.1
Jones, G.E.2
Brickell, P.M.3
Kinnon, C.4
Katz, D.R.5
Thrasher, A.J.6
-
134
-
-
0035663383
-
Monocytes from Wiskott-Aldrich patients differentiate in functional mature dendritic cells with a defect in CD83 expression
-
Allavena P, et al. Monocytes from Wiskott-Aldrich patients differentiate in functional mature dendritic cells with a defect in CD83 expression. Eur J Immunol 2001;31:3413-3421.
-
(2001)
Eur J Immunol
, vol.31
, pp. 3413-3421
-
-
Allavena, P.1
-
135
-
-
0035883097
-
Cdc42, Rac1, and the Wiskott-Aldrich syndrome protein are involved in the cytoskeletal regulation of B lymphocytes
-
Westerberg L, Greicius G, Snapper SB, Aspenström P, Severinson E. Cdc42, Rac1, and the Wiskott-Aldrich syndrome protein are involved in the cytoskeletal regulation of B lymphocytes. Blood 2001;98:1086-1094.
-
(2001)
Blood
, vol.98
, pp. 1086-1094
-
-
Westerberg, L.1
Greicius, G.2
Snapper, S.B.3
Aspenström, P.4
Severinson, E.5
-
136
-
-
0035174959
-
The interaction between Cdc42 and WASp is required for SDF-1-induced T-lymphocyte chemotaxis
-
Haddad E, et al. The interaction between Cdc42 and WASp is required for SDF-1-induced T-lymphocyte chemotaxis. Blood 2001;97:33-38.
-
(2001)
Blood
, vol.97
, pp. 33-38
-
-
Haddad, E.1
-
137
-
-
0033082452
-
Mena is required for neurulation and commissure formation
-
Lanier LM, et al. Mena is required for neurulation and commissure formation. Neuron 1999;22:313-325.
-
(1999)
Neuron
, vol.22
, pp. 313-325
-
-
Lanier, L.M.1
-
138
-
-
0035002333
-
N-WASp, WAVE Mena play different roles in the organization of actin cytoskeleton in lamellipodia
-
Nakagawa H, Miki H, Ho M, Ohashi K, Takenawa T, Miyamoto S. N-WASp, WAVE and Mena play different roles in the organization of actin cytoskeleton in lamellipodia. J Cell Sci 2001;114:1555-1565.
-
(2001)
J Cell Sci
, vol.114
, pp. 1555-1565
-
-
Nakagawa, H.1
Miki, H.2
Ho, M.3
Ohashi, K.4
Takenawa, T.5
Miyamoto, S.6
-
139
-
-
0037031144
-
Interaction of cortactin and N-WASp with Arp2/3 complex
-
Weaver AM, Heuser JE, Karginov AV, Lee WL, Parsons JT, Cooper JA. Interaction of cortactin and N-WASp with Arp2/3 complex. Curr Biol 2002;12:1270-1278.
-
(2002)
Curr Biol
, vol.12
, pp. 1270-1278
-
-
Weaver, A.M.1
Heuser, J.E.2
Karginov, A.V.3
Lee, W.L.4
Parsons, J.T.5
Cooper, J.A.6
-
140
-
-
0037178706
-
Role of formins in actin assembly: Nucleation and barbed-end association
-
Pryne D, et al. Role of formins in actin assembly: nucleation and barbed-end association. Science 2002;297:612-615.
-
(2002)
Science
, vol.297
, pp. 612-615
-
-
Pryne, D.1
-
141
-
-
0035877803
-
A role for Wiskott-Aldrich syndrome protein in T-cell receptor-mediated transcriptional activation independent of actin polymerization
-
Silvin C, Belisle B, Abo A. A role for Wiskott-Aldrich syndrome protein in T-cell receptor-mediated transcriptional activation independent of actin polymerization. J Biol Chem 2001;276:21450-21457.
-
(2001)
J Biol Chem
, vol.276
, pp. 21450-21457
-
-
Silvin, C.1
Belisle, B.2
Abo, A.3
-
142
-
-
0030461226
-
Control of EGF receptor signaling by clathrin-mediated endocytosis
-
Vieira AV, Lamaze C, Schmid SL. Control of EGF receptor signaling by clathrin-mediated endocytosis. Science 1996;274:2086-2089.
-
(1996)
Science
, vol.274
, pp. 2086-2089
-
-
Vieira, A.V.1
Lamaze, C.2
Schmid, S.L.3
-
143
-
-
0030613761
-
Switching of the coupling of the β2-adrenergic receptor to different G proteins by protein kinase A
-
Daaka Y, Luttrell LM, Lefkowitz RL. Switching of the coupling of the β2-adrenergic receptor to different G proteins by protein kinase A. Nature 1997;390:88-91.
-
(1997)
Nature
, vol.390
, pp. 88-91
-
-
Daaka, Y.1
Luttrell, L.M.2
Lefkowitz, R.L.3
-
144
-
-
0035313703
-
Expanding roles for β-arrestins as scaffolds and adaptors in GPCR signaling and trafficking
-
Miller WE, Lefkowitz RJ. Expanding roles for β-arrestins as scaffolds and adaptors in GPCR signaling and trafficking. Curr Opin Cell Biol 2001;13:139-145.
-
(2001)
Curr Opin Cell Biol
, vol.13
, pp. 139-145
-
-
Miller, W.E.1
Lefkowitz, R.J.2
-
145
-
-
0032101348
-
Membrane compartmentation is required for efficient T cell activation
-
Xavier R, Brennan T, Li Q, McCormack C, Seed B. Membrane compartmentation is required for efficient T cell activation. Immunity 1998;8:723-732.
-
(1998)
Immunity
, vol.8
, pp. 723-732
-
-
Xavier, R.1
Brennan, T.2
Li, Q.3
McCormack, C.4
Seed, B.5
-
146
-
-
17144439652
-
Phosphatidylinositol 4,5-biphosphate induces actin-based movement of raft-enriched vesicles through WASp-Arp 2/3
-
Rozelle AL, et al. Phosphatidylinositol 4,5-biphosphate induces actin-based movement of raft-enriched vesicles through WASp-Arp 2/3. Curr Biol 2000;10:311-320.
-
(2000)
Curr Biol
, vol.10
, pp. 311-320
-
-
Rozelle, A.L.1
-
147
-
-
0036669692
-
Wiskott-Aldrich syndrome protein regulates lipid raft dynamics during immunological synapse formation
-
Dupré L, et al. Wiskott-Aldrich syndrome protein regulates lipid raft dynamics during immunological synapse formation. Immunity 2002;17:157-166.
-
(2002)
Immunity
, vol.17
, pp. 157-166
-
-
Dupré, L.1
|