Involvement of Wiskott-Aldrich syndrome protein in B-cell cytoplasmic tyrosine kinase pathway

Blood

Volumn 93, Issue 6, 1999, Pages 2003-2012

  Baba, Yoshihiro ^a,b,c,d,e   Nonoyama, Shigeaki ^a,b,c,d,e   Matsushita, Masato ^a,b,c,d,e   Yamadori, Tomoki ^a,b,c,d,e   Hashimoto, Shoji ^a,b,c,d,e   Imai, Kohsuke ^a,b,c,d,e   Arai, Shigeyuki ^a,b,c,d,e   Kunikata, Toshio ^a,b,c,d,e   Kurimoto, Masashi ^a,b,c,d,e   Kurosaki, Tomohiro ^a,b,c,d,e   Ochs, Hans D ^a,b,c,d,e   Yata, Jun Ichi ^a,b,c,d,e   Kishimoto, Tadamitsu ^a,b,c,d,e   Tsukada, Satoshi ^a,b,c,d,e  

^a OSAKA UNIVERSITY MEDICAL SCHOOL   (Japan)

^b TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^c HAYASHIBARA BIOCHEMICAL LABORATORIES INC   (Japan)

^d KANSAI MEDICAL UNIVERSITY   (Japan)

^e UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GENE PRODUCT; LYMPHOCYTE ANTIGEN RECEPTOR; PROTEIN TYROSINE KINASE;

ARTICLE; B LYMPHOCYTE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME SPECIFICITY; ENZYME SUBSTRATE COMPLEX; GENE EXPRESSION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CROSS LINKING; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; WISKOTT ALDRICH SYNDROME;

EID: 0033559321     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v93.6.2003.406k13_2003_2012     Document Type: Article

References (63)

1. Tsukada S, Saffran DC, Rawlings DJ, Parolini O, Allen RC, Klisak I, Sparkes RS, Kubagawa H, Mohandas T, Quan S, Belmont JW, Cooper MD, Conley ME, Witte ON: Deficient expression of a B cell cytoplasmic tyrosine kinase in human X-linked agammaglobulinemia. Cell 72:279, 1993
2. Vetrie D, Vorechovsky I, Sideras P, Holland J, Davies A, Flinter F, Hammarström L, Kinnon C, Levinsky R, Bobrow M, Smith CIE, Bentley DR: The gene involved in X-linked agammaglobulinaemia is a member of the src family of protein-tyrosine kinases. Nature 361:226, 1993
3. Thomas JD, Sideras P, Smith CIE, Vorechovsky I, Chapman V, Paul WE: Colocalization of X-linked agammaglobulinemia and X-linked immunodeficiency genes. Science 261:355, 1993
4. Rawlings DJ, Saffran DC, Tsukada S, Largaespada DA, Grimaldi JC, Cohen L, Mohr RN, Bazan JF, Howard M, Copeland NG, Jenkins NA, Witte ON: Mutation of unique region of Bruton's tyrosine kinase in immunodeficient XID mice. Science 261:358, 1993
5. Saouaf SJ, Mahajan S, Rowley RB, Kut SA, Fargnoli J, Burkhardt AL, Tsukada S, Witte ON, Bolen JB: Temporal differences in the activation of three classes of non-transmembrane protein tyrosine kinases following B-cell antigen receptor surface engagement. Proc Natl Acad Sci USA 91:9524, 1994
6. de Weers M, Brouns GSm Hinshelwood S, Kinnon C, Schuurman RK, Hendriks RW, Borst J: B-cell antigen receptor stimulation activates the human Bruton's tyrosine kinase, which is deficient in X-linked agammaglobulinemia. J Biol Chem 269:23857, 1994
7. Aoki Y, Isselbacher KJ, Pillai S: Bruton tyrosine kinase is tyrosine phosphorylated and activated in pre-B lymphocytes and receptor-ligated B cells. Proc Natl Acad Sci USA 91:10606, 1994
8. Takata M, Kurosaki T: A role for Bruton's tyrosine kinase in B cell antigen receptor-mediated activation of phospholipase C-γ 2. J Exp Med 184:31, 1996
9. 2+ following B-cell receptor activation. EMBO J 17:1973, 1998
10. Kawakami Y, Yao L, Miura T, Tsukada S, Witte ON, Kawakami T: Tyrosine phosphorylation and activation of Bruton tyrosine kinase upon Fc∈RI cross-linking. Mol Cell Biol 14:5108, 1994
11. Sato S, Katagiri T, Takaki S, Kikuchi Y, Hitoshi Y, Yonehara S, Tsukada S, Kitamura D, Watanabe T, Witte ON, Takatsu K: IL-5 receptor-mediated tyrosine phosphorylation of SH2/SH3-containing proteins and activation of Bruton's tyrosine and Janus 2 kinases. J Exp Med 180:2101, 1994
12. Kikuchi Y, Yasue T, Miyake K, Kimoto M, Takatsu K: CD38 ligation induces tyrosine phosphorylation of Bruton tyrosine kinase and enhanced expression of interleukin 5-receptor α chain: Synergistic effects with interleukin 5. Proc Natl Acad Sci USA 92:11814, 1995
13. Tsukada S, Rawlings DJ, Witte ON: Role of Bruton's tyrosine kinase in immunodeficiency. Curr Opin Immunol 6:623, 1994
14. Cheng G, Ye ZS, Baltimore D: Binding of Bruton's tyrosine kinase to Fyn, Lyn, or Hck through a Src homology 3 domain-mediated interaction. Proc Natl Acad Sci USA 91:8152, 1994
15. Yao L, Kawakami Y, Kawakami T: The pleckstrin homology domain of Bruton tyrosine kinase interacts with protein kinase C. Proc Natl Acad Sci USA 91:9175, 1994
16. Tsukada S, Simon MI, Witte ON, Katz A: Binding of β-γ subunits of heterotrimeric G proteins to the PH domain of Bruton tyrosine kinase. Proc Natl Acad Sci USA 91:11256, 1994
17. Yang W, Malek SN, Desiderio S: An SH3-binding site conserved in Bruton's tyrosine kinase and related tyrosine kinases mediates specific protein interactions in vitro and in vivo. J Biol Chem 270:20832, 1995
18. Yang W, Desiderio S: BAP-135, a target for Bruton's tyrosine kinase in response to B cell receptor engagement. Proc Natl Acad Sci USA 94:604, 1997
19. Matsushita M, Yamadori T, Kato S, Takemoto Y, Inazawa J, Baba Y, Hashimoto S, Sekine S, Arai S, KunikataT, Kurimoto M, Kishimoto T, Tsukada S: Identification and characterization of a novel SH3-domain binding protein. Sab, which preferentially associates with Bruton's tyrosine kinase (Btk). Biochem Biophys Res Commun 245:337, 1998
20. Aldrich RA, Steinberg AG, Campbell DC: Pedigree demonstrating a sex-linked recessive condition characterized by draining ears, eczematoid dermatitis and bloody diarrhea. Pediatrics 13:133, 1954
21. Wolff JA: Wiskott-Aldrich syndrome: Clinical, immunologic, and pathologic observations. J Pediatr 70:221, 1967
22. Derry JMJ, Ochs HD, Francke U: Isolation of a novel gene mutated in Wiskott-Aldrich syndrome. Cell 78:635, 1994
23. Kolluri R, Tolias KF, Carpenter CL, Rosen FS, Kirchhausen T: Direct interaction of the Wiskott-Aldrich syndrome protein with the GTPase Cdc42. Proc Natl Acad Sci USA 93:5615, 1996
24. Symons M, Derry JMJ, Karlak B, Jiang S, Lemahieu V, McCormick F, Francke U, Abo A: Wiskott-Aldrich syndrome protein, a novel effector for the GTPase CDC42Hs, is implicated in actin polymerization. Cell 84:723, 1996
25. Lamarche N, Tapon N, Stowers L, Burbelo PD, Aspenström P, Bridges T, Chant J, Hall A: Rac and Cdc42 induce actin polymerization and G1 cell cycle progression independently of p65PAK and the JNK/SAPK MAP kinase cascade. Cell 87:519, 1996
26. Miki H, Sasaki T, Takai Y, Takenawa T: Induction of filopodium formaition by a WASP-related actin-depolymerizing protein N-WASP. Nature 391:93, 1998
27. Wengler G, Gorlin JB, Williamson JM, Rosen FS, Bing DH: Nonrandom inactivation of the X chromosome in early lineage hematopoietic cells in carriers of Wiskott-Aldrich syndrome. Blood 85:2471, 1995
28. Ochs HD, Slichter SJ, Harker LA, Von Behrens WE, Clark RA, Wedgwood RJ: The Wiskott-Aldrich syndrome: Studies of lymphocytes, granulocytes, and platelets. Blood 55:243, 1980
29. Blaese RM, Strober W, Brown RS, Waldmann TA: The Wiskott-Aldrich syndrome. A disorder with a possible defect in antigen processing or recognition. Lancet 1:1056, 1968
30. Simon HU, Mills GB, Hashimoto S, Siminovitch KA: Evidence for defective transmembrane signaling in B cells from patients with Wiskott-Aldrich syndrome. J Clin Invest 90:1396, 1992
31. Rivero-Lezcano OM, Marcilla A, Sameshima JH, Robbins KC: Wiskott-Aldrich syndrome protein physically associates with Nek through Src homology 3 domains. Mol Cell Biol 15:5725, 1995
32. Bunnell SC, Henry PA, Kolluri R, Kirchhausen T, Rickles RJ, Berg LJ: Identification of Itk/Tsk Src homology 3 domain ligands. J Biol Chem 271:25646, 1996
33. Cory GOC, MacCarthy Morrogh L, Banin S, Gout I, Brickell PM, Levinsky RJ, Kinnon C, Lovering RC: Evidence that the Wiskott-Aldrich syndrome protein may be involved in lymphoid cell signaling pathways. J Immunol 157:3791, 1996
34. Banin S, Truong O, Katz DR, Waterfield MD, Brickell PM, Gout I: Wiskott-Aldrich syndrome protein (WASp) is a binding partner for c-Src family protein-tyrosine kinases. Curr Biol 6:981, 1996
35. Miki H, Nonoyama S, Zhu Q, Aruffo A, Ochs HD, Takenawa T: Tyrosine kinase signaling regulates Wiskott-Aldrich syndrome protein function, which is essential for megakaryocyte differentiation. Cell Growth Differ 8:195, 1997
36. Wu Y, Spencer SD, Lasky LA: Tyrosine phosphorylation regulates the SH3-mediated binding of the Wiskott-Aldrich syndrome protein to PSTPIP, a cytoskeletal-associated protein. J Biol Chem 273:5765, 1998
37. Klein G, Giovanella B, Westman A, Stehlin JS, Mumford D: An EBV-genome-negative cell line established from an American Burkitt lymphoma: receptor characteristics. EBV infectibility and permanent conversion into EBV-positive sublines by in vitro infection. Intervirology 5:319, 1975
38. Hurwitz R, Hozier J, LeBien T, Minowada J, Gajl Peczalska K, Kubonishi I, Kersey J: Characterization of a leukemic cell line of the pre-B phenotype. Int J Cancer 23:174, 1979
39. Kuwahara K, Kawai T, Mitsuyoshi S, Matsuo Y, Kikuchi H, Imajoh Ohmi S, Hashimoto E, Inui S, Cooper MD, Sakaguchi N: Cross-linking of B cell antigen receptor-related structure of pre-B cell lines induces tyrosine phosphorylation of p85 and p110 subunits and activation of phosphatidylinositol 3-kinase. Int Immunol 8:1273, 1996
40. Kohno S, Minowada J, Sandberg AA: Chromosome evolution of near-haploid clones in an established human acute lymphoblastic leukemia cell line (NALM-16). J Natl Cancer Inst 64:485, 1980
41. Pear WS, Nolan GP, Scott ML, Baltimore D: Production of high titer helper-free retroviruses by transient transfection. Proc Natl Acad Sci USA 90:8392, 1993
42. Zhu Q, Watanabe C, Liu T, Hollenbaugh D, Blaese RM, Kanner SB, Aruffo A, Ochs HD: Wiskott-Aldrich syndrome/X-linked thrombocytopenia: WASP gene mutations, protein expression, and phenotype. Blood 90:2680, 1997
43. Hashimoto S, Tsukada S, Matsushita M, Miyawaki T, Niida Y, Yachie A, Kobayashi S, Iwata T, Hayakawa H, Matsuoka H, Tsuge I, Yamadori T, Kunikata T, Arai S, Yoshizaki K, Taniguchi N, Kishimoto T: Identification of Bruton's tyrosine kinase (Btk) gene mutations and characterization of the derived proteins in 35 X-linked agammaglobulinemia families: A nationwide study of Btk deficiency in Japan. Blood 88:561, 1996
44. Futatani T, Miyawaki T, Tsukada S, Hashimoto S, Kunikata T, Arai S, Kurimoto M, Niida Y, Matsuoka H, Sakiyama Y, Iwata T, Tsuchiya S, Tatsuzawa O, Yoshizaki K, Kishimoto T: Deficient expression of Bruton's tyrosine kinase in monocytes from X-linked Agammaglobulinemia as evaluated by a flowcytometric analysis and its clinical appliation to carrier detection. Blood 91:595, 1998
45. Mizushima S, Nagata S: pEF-BOS, a powerful mammalian expression vector. Nucleic Acids Res 18:5322, 1990
46. Zhu Q, Zhang M, Blaese RM, Derry JMJ, Junker A, Francke U, Chen SH, Ochs HD: The Wiskott-Aldrich syndrome and X-linked congenital thrombocytopenia are caused by mutations of the same gene. Blood 86:3797, 1995
47. Takemoto Y, Sato M, Furuta M, Hashimoto Y: Expression plasmid vectors with convenient subcloning sites in lambda gt11 that efficiently produce detectable tagged proteins. DNA Cell Biol 16:893, 1997
48. Konopka JB, Davis RL, Watanabe SM, Ponticelli AS, Schiff-Marker L, Rosenberg N, Witte ON: Only site-directed antibodies reactive with the highly conserved src-homologous region of the v-abl protein neutralize kinase activity. J Virol 51:223, 1988
49. Cory GOC, Lovering RC, Hinshelwood S, MacCarthy Morrogh L, Levinsky RJ, Kinnon C: The protein product of the c-cbl protooncogene is phosphorylated after B cell receptor stimulation and binds the SH3 domain of Bruton's tyrosine kinase. J Exp Med 182:611, 1995
50. Rawlings DJ, Scharenberg AM, Park H, Wahl MI, Lin S, Kato RM, Fluckiger AC, Witte ON, Kinet JP: Activation of BTK by a phosphorylation mechanism initiated by SRC family kinases. Science 271:822, 1996
51. Yu H, Rosen MK, Shin TB, Seidel Dugan C, Brugge JS, Schreiber SL: Solution structure of the SH3 domain of Src and identification of its ligand-binding site. Science 258:1665, 1992
52. Yu H, Chen JK, Feng S, Dalgarno DC, Brauer AW, Schreiber SL: Structural basis for the binding of proline-rich peptides to SH3 domains. Cell 76:933, 1994
53. Lee CH, Saksela K, Mirza UA, Chait BT, Kuriyan J: Crystal structure of the conserved core of HFV-1 Nef complexed with a Src family SH3 domain. Cell 85:931, 1996
54. Mahajan S, Fargnoli J, Burkhardt AL, Kut SA, Saouaf SJ, Bolen JB: Src family protein tyrosine kinases induce autoactivation of Bruton's tyrosine kinase. Mol Cell Biol 15:5304, 1995
55. Park H, Wahl MI, Afar DEH, Turck CW, Rawlings DJ, Tam C, Scharenberg AM, Kinet JPm Witte ON: Regulation of Btk function by a major autophosphorylation site within the SH3 domain. Immunity 4:515, 1996
56. Huyer G, Liu S, Kelly J, Moffat J, Fayette P, Kennedy B, Tsaprailis G, Gresser MJ, Ramachandran C: Mechanism of inhibition of protein-tyrosine phosphatases by vanadate and pervanadate. J Biol Chem 272:843, 1997
57. Fantus IG, Kadota S, Deragon G, Foster B, Posner BI: Pervanadate [peroxide(s) of vanadate] mimics insulin action in rat adipocytes via activation of the insulin receptor tyrosine kinase. Biochemistry 28:8864, 1989
58. Secrist JP, Burns LA, Karnitz L, Koretzky GA, Abraham RT: Stimulatory effects of the protein tyrosine phosphatase inhibitor, pervanadate, on T-cell activation events. J Biol Chem 268:5886, 1993
59. Wienands J, Larbolette O, Reth M: Evidence for a preformed transducer complex organized by the B cell antigen receptor. Proc Natl Acad Sci USA 93:7865, 1996
60. Guinamard R, Fougereau M, Seckinger P: The SH3 domain of Bruton's tyrsosine kinase interacts with Vav, Sam68 and EWS. Scand J Immunol 45:587, 1997
61. Zhou S, Carraway KLR, Eck MJ, Harrison SC, Feldman RA, Mohammadi M, Schlessinger J, Hubbard SR, Smith DP, Eng C, Lorenzo MJ, Ponder BAJ, Mayer BJ, Cantley LC: Catalytic specificity of protein-tyrosine kinases is critical for selective signalling. Nature 373:536, 1995
62. Schmitz R, Baumann G, Gram H: Catalytic specificity of phosphotyrosine kinases Blk, Lyn, c-Src and Syk as assessed by phage display. J Mol Biol 260:664, 1996
63. Hanks SK, Hunter T: The eukaryotic protein kinase superfamily: Kinase (catalytic) domain structure and classification. FASEB J 9:576, 1995