The hepatitis C viral NS3 protein is a processive DNA helicase with cofactor enhanced RNA unwinding

EMBO Journal

Volumn 21, Issue 5, 2002, Pages 1168-1176

  Pang, Phillip S ^a,b   Jankowsky, Eckhard ^c   Planet, Paul J ^a,b   Pyle, Anna Marie ^a  

^a Columbia University ^*  (United States)

^b The New York Presbyterian Hospital   (United States)

^c CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

D; DExH; Helicase; Hepatitis C; NS3; NS4A

Indexed keywords

HELICASE; NONSTRUCTURAL PROTEIN 3; PROTEIN NS4A; RNA HELICASE; UNCLASSIFIED DRUG; VIRUS PROTEIN;

ARTICLE; DNA DENATURATION; DNA RNA HYBRIDIZATION; DRUG TARGETING; ENZYME ACTIVITY; ENZYME SPECIFICITY; ENZYME STRUCTURE; HEPATITIS C; HEPATITIS C VIRUS; NONHUMAN; PHYLOGENY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN PROTEIN INTERACTION; RNA STRUCTURE; VIRUS INHIBITION; VIRUS REPLICATION;

BASE SEQUENCE; DNA; DNA HELICASES; EVOLUTION, MOLECULAR; HEPACIVIRUS; HUMANS; MACROMOLECULAR SUBSTANCES; MOLECULAR SEQUENCE DATA; PHYLOGENY; RNA, VIRAL; SUBSTRATE SPECIFICITY; VIRAL NONSTRUCTURAL PROTEINS;

HEPATITIS C VIRUS; RNA VIRUSES;

EID: 0036500976     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/21.5.1168     Document Type: Article

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