Specific interaction of hepatitis C virus protease/helicase NS3 with the 3′-terminal sequences of viral positive- and negative-strand RNA

Journal of Virology

Volumn 75, Issue 4, 2001, Pages 1708-1721

  Banerjee, R ^a   Dasgupta, A ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GUANOSINE DERIVATIVE; HELICASE; HELICASE NS3; NUCLEOTIDE; PROTEINASE; UNCLASSIFIED DRUG; VIRUS ENZYME; VIRUS RNA;

ARTICLE; CONTROLLED STUDY; GENE DELETION; GENE STRUCTURE; GENETIC CODE; HEPATITIS C VIRUS; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN RNA BINDING; RNA REPLICATION; RNA SEQUENCE; RNA SYNTHESIS; RNA TRANSLATION; VIRUS REPLICATION;

3' UNTRANSLATED REGIONS; BASE PAIRING; BASE SEQUENCE; HEPACIVIRUS; MOLECULAR SEQUENCE DATA; PROTEIN BIOSYNTHESIS; RNA, VIRAL; TRANSCRIPTION, GENETIC; VIRAL NONSTRUCTURAL PROTEINS;

EID: 0035138086     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.75.4.1708-1721.2001     Document Type: Article

References (60)

1. In vitro replication of RNA viruses
2. Polio virus-encoded 2C polypeptide specifically binds to the 3′-terminal sequences of viral negative-strand RNA
3. Kinetic and structural analyses of hepatitis C virus polyprotein processing
4. Complex formation between the NS3 serine-type proteinase of the hepatitis C virus and NS4A and its importance for polyprotein maturation
5. Structural organization of poliovirus RNA replication is mediated by viral proteins of the P2 genomic regions
6. Secondary-structure determination of the conserved 98-base sequence at the 3′ terminus of hepatitis C virus genome RNA
7. Secondary structure of the 5′ nontranslated regions of hepatitis C virus and pestivirus genomic RNAs
8. Sequence analysis of the 5′ coding region of hepatitis C virus
9. Crystal structure of RNA helicase from genotype 1b hepatitis C virus. A feasible mechanism of unwinding duplex RNA
10. Membrane rearrangement and vesicle induction by recombinant poliovirus 2C and 2BC in human cells
11. Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome
12. Molecular virology of hepatitis C virus
13. Amino terminal region of poliovirus 2C is sufficient for membrane binding
14. Amino terminal region of poliovirus 2C mediates membrane binding
15. Both NS3 and NS4 are required for processing of hepatitis C virus nonstructural proteins
16. Characterization of the hepatitis C virus-encoded serine proteinase: Determination of the proteinase-dependent polyprotein cleavage sites
17. Expression and identification of hepatitis C virus polyprotein cleavage products
18. A second hepatitis C virus encoded proteinase
19. Characterization of RNA binding and RNA helicase activity of the hepatitis C virus NS3 protein
20. A phylogenetically conserved stem-loop structure at the 5′ border of the internal ribosome entry site of hepatitis C virus is required for cap-independent viral translation
21. Stability of a stem loop involving the initiator AUG controls the efficiency of internal initiation of translation on hepatitis C virus RNA
22. Genomic structure of the human prototype strain H of hepatitis C virus: Comparison with American and Japanese isolates
23. Complex formation of NS5B with NS3 and NS4A proteins of hepatitis C virus
24. Determination of the secondary structure of and cellular proteins binding to the 3′ untranslated region of the hepatitis C virus RNA genome
25. Expression, isolation and characterization of the hepatitis C virus ATPase-RNA helicase
26. Poly(U) binding activity of hepatitis C virus NS3 protein, a putative RNA helicase
27. Association between NS3 and NS5 proteins of dengue virus type 2 in the putative RNA replicase is linked to differential phosphorylation of NS5
28. Molecular cloning of the hepatitis C virus genome from Japanese patients with non A, non B hepatitis
29. Crystal structure of the hepatitis C virus protease domain complexed with a synthetic NS4A cofactor peptide
30. Identification of a highly conserved sequence element at the 3′ terminus of hepatitis C virus genome RNA
31. Specificity of the hepatitis C NS3 serine protease: Effects of substitution at the 3/4A, 4A/4B, 4B/5A, and 5A/5B cleavage sites on polyprotein processing
32. Transmission of hepatitis C by intrahepatic inoculation with transcribed RNA
33. A central region in the hepatitis C virus NS4A protein allows formation of active NS3-NS4A serine proteinase complex in vivo and in vitro
34. Hepatitis C virus NS3 serine proteinase: Trans cleavage requirements and processing kinetics
35. Structure-based mutagenesis study of hepatitis C virus NS3 helicase
36. Replication of subgenomic hepatitis C virus RNA in a hepatoma cell line
37. The crystal structure of hepatitis C virus NS3 proteins reveals a trypsin-like fold and a structural zinc binding site
38. De novo initiation of RNA synthesis by the RNA-dependent RNA polymerase (NS5B) of hepatitis C virus
39. Biochemical studies on poliovirus polypeptide 2C: Evidence for ATPase activity
40. A recombinant hepatitis C virus RNA-dependent RNA polymerase capable of copying the full-length viral RNA
41. Characterization of the nucleoside triphosphatase activity of poliovirus protein 2C reveals a mechanism by which guanidine inhibits poliovirus replication
42. A kinetic analysis of the oligonucleotide modulated ATPase activity of the helicase domain of the NS3 protein from hepatitis C virus. The first cycle of interaction of ATP with the enzyme is unique
43. A steady-state and pre-steady-state kinetic analysis of the NTPase activity associated with the hepatitis C virus NS3 helicase domain
44. Flaviviridae: The viruses and their replication
45. Hepatitis C virus infection is associated with the development of hepatocellular carcinoma
46. Hepatitis C virus NS3 protein polynucleotide-stimulated nucleoside triphosphatase and comparison with the related pestivirus and flavivirus enzymes
47. The helicase activity associated with hepatitis C virus nonstructural protein (NS3)
48. Structure of the 3′ terminus of the hepatitis C virus genome
49. Hepatitis C virus-encoded nonstructural protein NS4A has versatile functions in viral protein processing
50. NS3 is a serine protease required for processing of hepatitis C virus polyprotein
51. Internal ribosome entry site within hepatitis C virus
52. Hepatitis C virus RNA polymerase and NS5A complex with a SNARE-like protein
53. A conserved helical element is essential for internal initiation of translation of hepatitis C virus RNA
54. Subcellular localization, stability, and trans cleavage competence of the hepatitis C virus NS3-NS4A complex expressed in tetracycline-regulated cell lines
55. Genetic organization and diversity of the 3′ noncoding region of the hepatitis C virus genome
56. In vivo analysis of the 3′ UTR of the hepatitis C virus after in vitro mutagenesis of an infectious cDNA clone
57. Transcripts from a single full length cDNA clone of hepatitis C virus are infectious when directly transfected into the liver of a chimpanzee
58. Transcripts of a chimeric cDNA clone of hepatitis C virus genotype 1b are infectious in vivo
59. Structure of the hepatitis C virus RNA helicase domain
60. De novo initiation of RNA synthesis by hepatis C virus nonstructural protein 5B polymerase