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Journal of Organic Chemistry

Volumn 66, Issue 18, 2001, Pages 6158-6163

Structure-activity studies of antitumor agent irofulven (Hydroxymethylacylfulvene) and analogues

(8) McMorris, T C a Yu, J a Lira, R a Dawe, R b MacDonald, J R b Waters, S J b Estes, L A c Kelner, M J c

a UNIVERSITY OF CALIFORNIA (United States)

b GUILFORD PHARMACEUTICALS INC (United States)

c UCSD MEDICAL CENTER (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NUCLEOPHILES;

BIODIVERSITY; TOXICITY;

ONCOLOGY;

6 HYDROXYMETHYLACYLFULVENE; ACROLEIN; ANTINEOPLASTIC AGENT; SESQUITERPENE;

ALKYLATION; ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL COMPARTMENTALIZATION; DNA STRAND BREAKAGE; DNA SYNTHESIS INHIBITION; REACTION ANALYSIS; STRUCTURE ACTIVITY RELATION; XENOGRAFT;

ANIMALS; ANTINEOPLASTIC AGENTS, ALKYLATING; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MICE; SESQUITERPENES; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 0035823281 PISSN: 00223263 EISSN: None Source Type: Journal
DOI: 10.1021/jo010458z Document Type: Article

Times cited : (28)

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