-
1
-
-
0014593403
-
Positional information and the spatial pattern of cellular differentiation
-
Wolpert, L. Positional information and the spatial pattern of cellular differentiation. J. Theor. Biol. 25, 1-47 (1969).
-
(1969)
J. Theor. Biol.
, vol.25
, pp. 1-47
-
-
Wolpert, L.1
-
2
-
-
0030604688
-
Morphogens, compartments, and patterns: Lessons from Drosophila?
-
Lawrence, P. A. & Struhl, S. Morphogens, compartments, and patterns: lessons from Drosophila? Cell 85, 951-961 (1996).
-
(1996)
Cell
, vol.85
, pp. 951-961
-
-
Lawrence, P.A.1
Struhl, S.2
-
3
-
-
0025325505
-
Secreted int-1 protein is associated with the cell surface
-
Papkoff, J. & Schryver, B. Secreted int-1 protein is associated with the cell surface. Mol. Cell. Biol. 10, 2723-2730 (1990).
-
(1990)
Mol. Cell. Biol.
, vol.10
, pp. 2723-2730
-
-
Papkoff, J.1
Schryver, B.2
-
4
-
-
0025240833
-
The proto-oncogene int-1 encodes a secreted protein associated with the extracellular matrix
-
Bradley, R. S. & Brown, A. M. The proto-oncogene int-1 encodes a secreted protein associated with the extracellular matrix. EMBO J. 9, 1569-1575 (1990).
-
(1990)
EMBO J.
, vol.9
, pp. 1569-1575
-
-
Bradley, R.S.1
Brown, A.M.2
-
5
-
-
0029844192
-
Cholesterol modification of Hedgehog signaling proteins in animal development
-
Porter, J. A., Young, K. E. & Beachy, P. A. Cholesterol modification of Hedgehog signaling proteins in animal development. Science 274, 255-259 (1996).
-
(1996)
Science
, vol.274
, pp. 255-259
-
-
Porter, J.A.1
Young, K.E.2
Beachy, P.A.3
-
6
-
-
15444359695
-
Identification of a palmitic acid-modified form of human Sonic hedgehog
-
Pepinsky, R. B. et al. Identification of a palmitic acid-modified form of human Sonic hedgehog. J. Biol. Chem. 273, 14037-14045 (1998).
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 14037-14045
-
-
Pepinsky, R.B.1
-
7
-
-
0033597141
-
Association of sterol- and glycosylphosphatidylinositol-linked proteins with Drosophila raft lipid microdomains
-
Rietveld, A., Neutz, S., Simons, K. & Eaton, S. Association of sterol- and glycosylphosphatidylinositol-linked proteins with Drosophila raft lipid microdomains. J. Biol. Chem. 274, 12049-12054 (1999).
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 12049-12054
-
-
Rietveld, A.1
Neutz, S.2
Simons, K.3
Eaton, S.4
-
8
-
-
0033598964
-
Dispatched, a novel sterol-sensing domain protein dedicated to the release of cholesterol-modified hedgehog from signaling cells
-
Burke, R. et al. Dispatched, a novel sterol-sensing domain protein dedicated to the release of cholesterol-modified hedgehog from signaling cells. Cell 99, 803-815 (1999).
-
(1999)
Cell
, vol.99
, pp. 803-815
-
-
Burke, R.1
-
9
-
-
12944272018
-
Receptor-mediated endocytosis of soluble and membrane-tethered Sonic hedgehog by Patched-1
-
Incardona, J. P. et al. Receptor-mediated endocytosis of soluble and membrane-tethered Sonic hedgehog by Patched-1. Proc. Natl Acad. Sci. USA 97, 12044-12049 (2000). This paper shows that membrane-tethered forms of Shh are released from the expressing cells and endocytosed by other cells, indicating that Shh is released and internalized together with its surrounding membrane.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 12044-12049
-
-
Incardona, J.P.1
-
10
-
-
0030663064
-
A Hedgehog activity gradient contributes to AP axial patterning of the Drosophila wing
-
Strigini, M. & Cohen, S. A Hedgehog activity gradient contributes to AP axial patterning of the Drosophila wing. Development 124, 4697-4705 (1997).
-
(1997)
Development
, vol.124
, pp. 4697-4705
-
-
Strigini, M.1
Cohen, S.2
-
11
-
-
9844220298
-
Relationship between dose, distance and time in Sonic hedgehog-mediated regulatior of anteroposterior polarity in the chick limb
-
Yang, Y. et al. Relationship between dose, distance and time in Sonic hedgehog-mediated regulatior of anteroposterior polarity in the chick limb. Development 124, 4393-4404 (1997).
-
(1997)
Development
, vol.124
, pp. 4393-4404
-
-
Yang, Y.1
-
12
-
-
0028208698
-
Subcellular localization of the segment polarity protein patched suggests an interaction with the wingless receptor complex in Drosophila embryos
-
Capdevila, J., Pariente, F., Sampedro, Alonso, J. L. & Guerrero, I. Subcellular localization of the segment polarity protein patched suggests an interaction with the wingless receptor complex in Drosophila embryos. Development 120, 987-998 (1994).
-
(1994)
Development
, vol.120
, pp. 987-998
-
-
Capdevila, J.1
Pariente, F.2
Sampedro3
Alonso, J.L.4
Guerrero, I.5
-
13
-
-
0035901616
-
The sterolsensing domain of Patched protein seems to control Smoothened activity through Patched vesicular trafficking
-
Martin, V, Carrillo, G., Torroja, C. & Guerrero, I. The sterolsensing domain of Patched protein seems to control Smoothened activity through Patched vesicular trafficking. Curr. Biol. 11, 601-607 (2001).
-
(2001)
Curr. Biol.
, vol.11
, pp. 601-607
-
-
Martin, V.1
Carrillo, G.2
Torroja, C.3
Guerrero, I.4
-
14
-
-
0026632816
-
The bride of sevenless and sevenless interaction: Internalization of a transmembrane ligand
-
Cagan, R. L., Kramer, H., Hart, A. C. & Zipursky, S. L. The bride of sevenless and sevenless interaction: internalization of a transmembrane ligand. Cell 69, 393-399 (1992).
-
(1992)
Cell
, vol.69
, pp. 393-399
-
-
Cagan, R.L.1
Kramer, H.2
Hart, A.C.3
Zipursky, S.L.4
-
15
-
-
0028148335
-
Jag-2 may encode a signaling ligand for the GLP-1 and LIN-12 receptors of C. elegans
-
Henderson, S., Gao, D., Lamble, E. & Kimble, J. Jag-2 may encode a signaling ligand for the GLP-1 and LIN-12 receptors of C. elegans. Development 120, 2913-2924 (1994).
-
(1994)
Development
, vol.120
, pp. 2913-2924
-
-
Henderson, S.1
Gao, D.2
Lamble, E.3
Kimble, J.4
-
16
-
-
0031846155
-
Complex proteolytic processing acts on Delta, a transmembrane ligand for Notch, during Drosophila development
-
Klueg, K. M., Parody, T. R. & Muskavitch, M. A. T. Complex proteolytic processing acts on Delta, a transmembrane ligand for Notch, during Drosophila development. Mol. Biol. Cell 9, 1709-1723 (1998).
-
(1998)
Mol. Biol. Cell
, vol.9
, pp. 1709-1723
-
-
Klueg, K.M.1
Parody, T.R.2
Muskavitch, M.A.T.3
-
17
-
-
0032705926
-
Ligand-receptor interactions and trans-endocytosis of Delta, Serrate and Notch: Members of the Notch signalling pathway in Drosophila
-
Klueg, K. & Muskavitch, M. Ligand-receptor interactions and trans-endocytosis of Delta, Serrate and Notch: members of the Notch signalling pathway in Drosophila. J. Cell Sci. 112, 3289-3297 (1999).
-
(1999)
J. Cell Sci.
, vol.112
, pp. 3289-3297
-
-
Klueg, K.1
Muskavitch, M.2
-
18
-
-
0035823004
-
Argosomes. A potential vehicle for the spread of morphogens through epithelia
-
Greco, V., Hannus, M. & Eaton, S. Argosomes. A potential vehicle for the spread of morphogens through epithelia. Cell 106, 633-645 (2001). This study shows that membrane-anchored GFP-GPI and myristilated Rho-CFP are released from donor cells and endocytosed in receiving cells, implying that membrane pieces (argosomes) can travel throughout a developing tissue.
-
(2001)
Cell
, vol.106
, pp. 633-645
-
-
Greco, V.1
Hannus, M.2
Eaton, S.3
-
19
-
-
0036676445
-
Exosomes: Composition, biogenesis and function
-
Thery, C., Zitvogel, L. & Amigorena, S. Exosomes: composition, biogenesis and function. Nature Rev. Immunol. 2, 569-579 (2002).
-
(2002)
Nature Rev. Immunol.
, vol.2
, pp. 569-579
-
-
Thery, C.1
Zitvogel, L.2
Amigorena, S.3
-
20
-
-
0036237642
-
The biogenesis and functions of exosomes
-
Stoorvogel, W., Kleijmeer, M. J., Geuze, H. J. & Raposo, G. The biogenesis and functions of exosomes. Traffic 3, 321-330 (2002).
-
(2002)
Traffic
, vol.3
, pp. 321-330
-
-
Stoorvogel, W.1
Kleijmeer, M.J.2
Geuze, H.J.3
Raposo, G.4
-
21
-
-
0023645106
-
Vesicle formation during reticulocyte maturation. Association of plasma membrane activities with released vesicles (exosomes)
-
Johnstone, R. M., Adam, M., Hammond, J. R., Orr, L. & Turbide, C. Vesicle formation during reticulocyte maturation. Association of plasma membrane activities with released vesicles (exosomes). J. Biol. Chem. 262, 9412-9420 (1987).
-
(1987)
J. Biol. Chem.
, vol.262
, pp. 9412-9420
-
-
Johnstone, R.M.1
Adam, M.2
Hammond, J.R.3
Orr, L.4
Turbide, C.5
-
22
-
-
0022201056
-
Electron microscopic evidence for externalization of the transferrin receptor in vesicular form in sheep reticulocytes
-
Pan, B. T., Teng, K., Wu, C., Adam, M. & Johnstone, R. M. Electron microscopic evidence for externalization of the transferrin receptor in vesicular form in sheep reticulocytes. J. Cell Biol. 101, 942-948 (1985).
-
(1985)
J. Cell Biol.
, vol.101
, pp. 942-948
-
-
Pan, B.T.1
Teng, K.2
Wu, C.3
Adam, M.4
Johnstone, R.M.5
-
23
-
-
0036144685
-
Immunoelectron microscopic localization of cholesterol using biotinylated and non-cytolytic Perfringolysin O
-
Mobius, W. et al. Immunoelectron microscopic localization of cholesterol using biotinylated and non-cytolytic Perfringolysin O. J. Histochem. Cytochem. 50, 43-56 (2002).
-
(2002)
J. Histochem. Cytochem.
, vol.50
, pp. 43-56
-
-
Mobius, W.1
-
24
-
-
0032055112
-
Decay-accelerating factor (CD55) and membrane inhibitor of reactive lysis (CD59) are released within exosomes during in vitro maturation of reticulocytes
-
Rabesandratana, H., Toutant, J.-P., Reggio, H. & Vidal, M. Decay-accelerating factor (CD55) and membrane inhibitor of reactive lysis (CD59) are released within exosomes during in vitro maturation of reticulocytes. Blood 91, 2573-2580 (1998).
-
(1998)
Blood
, vol.91
, pp. 2573-2580
-
-
Rabesandratana, H.1
Toutant, J.-P.2
Reggio, H.3
Vidal, M.4
-
25
-
-
0032493658
-
Selective enrichment of tatraspen proteins on the internal vesicles of multivesicular endosomes and on exosomes secreted by human B-lymphocytes
-
Escola, J.-M. et al. Selective enrichment of tatraspen proteins on the internal vesicles of multivesicular endosomes and on exosomes secreted by human B-lymphocytes. J. Biol. Chem. 273, 20121-20127 (1998).
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 20121-20127
-
-
Escola, J.-M.1
-
26
-
-
0033566085
-
The cell-surface proteoglycan Daily regulates Wingless signalling in Drosophila
-
Tsuda, M. et al. The cell-surface proteoglycan Daily regulates Wingless signalling in Drosophila. Nature 400, 276-80 (1999).
-
(1999)
Nature
, vol.400
, pp. 276-280
-
-
Tsuda, M.1
-
27
-
-
0033566126
-
Dally cooperates with Drosophila Frizzled 2 to transduce Wingless signalling
-
Lin, X. & Perrimon, N. Dally cooperates with Drosophila Frizzled 2 to transduce Wingless signalling. Nature 400, 281-284 (1999).
-
(1999)
Nature
, vol.400
, pp. 281-284
-
-
Lin, X.1
Perrimon, N.2
-
28
-
-
0035152025
-
Heparan sulfate proteoglycans are critical for the organization of the extracellular distribution of Wingless
-
Baeg, G. H., Lin, X., Khare, N., Baumgartner, S. & Perrimon, N. Heparan sulfate proteoglycans are critical for the organization of the extracellular distribution of Wingless. Development 128, 87-94 (2001).
-
(2001)
Development
, vol.128
, pp. 87-94
-
-
Baeg, G.H.1
Lin, X.2
Khare, N.3
Baumgartner, S.4
Perrimon, N.5
-
29
-
-
0033639077
-
Gradient formation of the TGF-β homolog Dpp
-
Entchev, E. V., Schwabedissen, A. & Gonzalez-Gaitan, M. Gradient formation of the TGF-β homolog Dpp. Cell 103, 981-991 (2000). This study shows that endocytosis is required for the long-range dispersal of Dpp, and proposes a model of planar transcytosis of Dpp. Together with reference 30, this is the first visualization of concentration-gradient formation of a TGF-β superfamily ligand.
-
(2000)
Cell
, vol.103
, pp. 981-991
-
-
Entchev, E.V.1
Schwabedissen, A.2
Gonzalez-Gaitan, M.3
-
30
-
-
0033636094
-
Dpp gradient formation in the Drosophila wing imaginal disc
-
Teleman, A. A. & Cohen, S. M. Dpp gradient formation in the Drosophila wing imaginal disc. Cell 103, 971-980 (2000).
-
(2000)
Cell
, vol.103
, pp. 971-980
-
-
Teleman, A.A.1
Cohen, S.M.2
-
31
-
-
0029967209
-
Two distinct mechanisms for long-range patterning by decapentaplegic in the Drosophila wing
-
Lecuit, T. et al. Two distinct mechanisms for long-range patterning by decapentaplegic in the Drosophila wing. Nature 381, 387-393 (1996).
-
(1996)
Nature
, vol.381
, pp. 387-393
-
-
Lecuit, T.1
-
32
-
-
0029894568
-
Direct and long-range action of a DPP morphogen gradient
-
Nellen, N., Burke, R., Struhl, G. & Basler, K. Direct and long-range action of a DPP morphogen gradient. Cell 85, 357-368 (1996).
-
(1996)
Cell
, vol.85
, pp. 357-368
-
-
Nellen, N.1
Burke, R.2
Struhl, G.3
Basler, K.4
-
33
-
-
0028122987
-
Activin signalling and response to a morphagen gradient
-
Gurdon, J. B., Harger, P., Mitchell, A. & Lemaire, P. Activin signalling and response to a morphagen gradient. Nature 371, 487-492 (1994).
-
(1994)
Nature
, vol.371
, pp. 487-492
-
-
Gurdon, J.B.1
Harger, P.2
Mitchell, A.3
Lemaire, P.4
-
34
-
-
0036080430
-
Do morphogen gradients arise by diffusion?
-
Lander, A. D., Nie, Q. & Wan, F. Y. Do morphogen gradients arise by diffusion? Dev. Cell 2, 785-796 (2002). This paper reports the mathematical modelling of morphogen dispersal by diffusion, which challenges the model of planar transcytosis.
-
(2002)
Dev. Cell
, vol.2
, pp. 785-796
-
-
Lander, A.D.1
Nie, Q.2
Wan, F.Y.3
-
35
-
-
0035069536
-
Formation of a functional morphogen gradient by a passive process in tissue from the early Xenopus embryo
-
McDowell, N., Gurdon, J. B. & Grainger, D. J. Formation of a functional morphogen gradient by a passive process in tissue from the early Xenopus embryo. Int. J. Dev. Biol. 45, 199-207 (2001). The data In this article provide support for activin dispersal by diffusion. It also reports the first visualization of the activin gradient by immunostaining.
-
(2001)
Int. J. Dev. Biol.
, vol.45
, pp. 199-207
-
-
McDowell, N.1
Gurdon, J.B.2
Grainger, D.J.3
-
36
-
-
0032524323
-
The interpretation of position in a morphogen gradient as revealed by occupancy of activin receptors
-
Dyson, S. & Gurdon, J. B. The interpretation of position in a morphogen gradient as revealed by occupancy of activin receptors. Cell 93, 557-568 (1998).
-
(1998)
Cell
, vol.93
, pp. 557-568
-
-
Dyson, S.1
Gurdon, J.B.2
-
37
-
-
0025744384
-
Secretion and movement of wingless protein in the epidermis of the Drosophila embryo
-
Gonzalez, F., Swales, L. S., Bejsovec, A., Skaer, H. & Martinez Arias, A. Secretion and movement of wingless protein in the epidermis of the Drosophila embryo. Mech. Dev. 35, 43-54 (1991).
-
(1991)
Mech. Dev.
, vol.35
, pp. 43-54
-
-
Gonzalez, F.1
Swales, L.S.2
Bejsovec, A.3
Skaer, H.4
Martinez Arias, A.5
-
38
-
-
0028842141
-
Signaling activities of the Drosophila wingless gene are separately mutable and appear to be transduced at the cell surface
-
Bejsovec, A. & Wieschaus, E. Signaling activities of the Drosophila wingless gene are separately mutable and appear to be transduced at the cell surface. Genetics 139, 309-320 (1995).
-
(1995)
Genetics
, vol.139
, pp. 309-320
-
-
Bejsovec, A.1
Wieschaus, E.2
-
39
-
-
0034704824
-
Wingless gradient formation in the Drosophila wing
-
Strigini, M. & Cohen, S. M. Wingless gradient formation in the Drosophila wing. Curr. Biol. 10, 293-300 (2000).
-
(2000)
Curr. Biol.
, vol.10
, pp. 293-300
-
-
Strigini, M.1
Cohen, S.M.2
-
40
-
-
0035368514
-
Regulated endocytic routing modulates wingless signaling in Drosophila embryos
-
Dubois, L., Lecourtois, M., Alexandre, C., Hirst, E. & Vincent, J. P. Regulated endocytic routing modulates wingless signaling in Drosophila embryos. Cell 105, 613-624 (2001). Using a HRP-Wg fusion protein, this paper shows that the range of Wg signalling is controlled by Intracellular degradation of the ligand at the lysosome. It shows that the extent of Wg degradation is determined by EGF signalling.
-
(2001)
Cell
, vol.105
, pp. 613-624
-
-
Dubois, L.1
Lecourtois, M.2
Alexandre, C.3
Hirst, E.4
Vincent, J.P.5
-
42
-
-
0033597828
-
Engrailed and Hedgehog make the range of Wingless asymmetric in Drosophila embryos
-
Sanson, B., Alexandre, C., Fascetti, N. & Vincent, J. P. Engrailed and Hedgehog make the range of Wingless asymmetric in Drosophila embryos. Cell 98, 207-216 (1999).
-
(1999)
Cell
, vol.98
, pp. 207-216
-
-
Sanson, B.1
Alexandre, C.2
Fascetti, N.3
Vincent, J.P.4
-
43
-
-
0033566130
-
ovo/svb integrates Wingless and DER pathways to control epidermis differentiation
-
Payre, F., Vincent, A. & Carreno, S. ovo/svb integrates Wingless and DER pathways to control epidermis differentiation. Nature 400, 271-275 (1999).
-
(1999)
Nature
, vol.400
, pp. 271-275
-
-
Payre, F.1
Vincent, A.2
Carreno, S.3
-
44
-
-
0033213257
-
A role for the deep orange and carnation eye color genes in lysosomal delivery in Drosophila
-
Sevrioukov, E. A., He, J. P., Moghrabi, N., Sunic, A. & Kramer, H. A role for the deep orange and carnation eye color genes in lysosomal delivery in Drosophila. Mol. Cell 4, 479-486 (1999).
-
(1999)
Mol. Cell
, vol.4
, pp. 479-486
-
-
Sevrioukov, E.A.1
He, J.P.2
Moghrabi, N.3
Sunic, A.4
Kramer, H.5
-
45
-
-
0027257424
-
The Drosophila clathrin heavy chain gene function is essential in a multicellular organism
-
Bazinet, C., Katzen, A. L., Morgan, M., Mahowald, A. P. & Lemmon, S. K. The Drosophila clathrin heavy chain gene function is essential in a multicellular organism. Genetics 134, 1119-1134 (1993).
-
(1993)
Genetics
, vol.134
, pp. 1119-1134
-
-
Bazinet, C.1
Katzen, A.L.2
Morgan, M.3
Mahowald, A.P.4
Lemmon, S.K.5
-
46
-
-
0033280324
-
Adaptors for clathrin-mediated traffic
-
Kirchhausen, T. Adaptors for clathrin-mediated traffic. Annu. Rev. Cell Dev. Biol. 15, 705-732 (1999).
-
(1999)
Annu. Rev. Cell Dev. Biol.
, vol.15
, pp. 705-732
-
-
Kirchhausen, T.1
-
47
-
-
0035408008
-
Ras-activated endocytosis is mediated by the Rab5 guanine nucleotide exchange activity of RIN1
-
Tall, G. G., Barbieri, M. A., Stahl, P. D., & Horazdovsky, B. F. Ras-activated endocytosis is mediated by the Rab5 guanine nucleotide exchange activity of RIN1. Dev. Cell 1, 73-82 (2001).
-
(2001)
Dev. Cell
, vol.1
, pp. 73-82
-
-
Tall, G.G.1
Barbieri, M.A.2
Stahl, P.D.3
Horazdovsky, B.F.4
-
48
-
-
0034676451
-
The Eps8 protein coordinates EGF receptor signalling through Rac and trafficking through Rab5
-
Lanzetti, L. et al. The Eps8 protein coordinates EGF receptor signalling through Rac and trafficking through Rab5. Nature 408, 374-377 (2000). Together with reference 47, this study shows how EGF signalling controls endocytic trafficking of the EGFR by regulating Rab5 activity.
-
(2000)
Nature
, vol.408
, pp. 374-377
-
-
Lanzetti, L.1
-
49
-
-
0037123789
-
Clathrin adaptors really adapt
-
Kirchhausen, T. Clathrin adaptors really adapt. Cell 109, 413-416 (2002).
-
(2002)
Cell
, vol.109
, pp. 413-416
-
-
Kirchhausen, T.1
-
50
-
-
0032514874
-
A structural explanation for the recognition of tyrosine-based endocytotic signals
-
Owen, D. J. & Evans, P. R. A structural explanation for the recognition of tyrosine-based endocytotic signals. Science 282, 1327-1332 (1998).
-
(1998)
Science
, vol.282
, pp. 1327-1332
-
-
Owen, D.J.1
Evans, P.R.2
-
51
-
-
0037123766
-
Molecular architecture and functional model of the endocytic AP2 complex
-
Collins, B. M., McCoy, A. J., Kent, H. M., Evans, P. R. & Owen, D. J. Molecular architecture and functional model of the endocytic AP2 complex. Cell 109, 523-535 (2002).
-
(2002)
Cell
, vol.109
, pp. 523-535
-
-
Collins, B.M.1
McCoy, A.J.2
Kent, H.M.3
Evans, P.R.4
Owen, D.J.5
-
52
-
-
0035293622
-
Protein regulation by monoubiquitin
-
Hicke, L. Protein regulation by monoubiquitin. Nature Rev. Mol. Cell Biol. 2, 195-201 (2001).
-
(2001)
Nature Rev. Mol. Cell Biol.
, vol.2
, pp. 195-201
-
-
Hicke, L.1
-
53
-
-
0035823032
-
A new ticket for entry into budding vesicles ubiquitin
-
Hicke, L. A new ticket for entry into budding vesicles ubiquitin. Cell 106, 527-530 (2001).
-
(2001)
Cell
, vol.106
, pp. 527-530
-
-
Hicke, L.1
-
54
-
-
0030908698
-
Epidermal growth factor induces ubiquitination of Eps15
-
van Delft, S., Govers, R., Strous, G. J., Verkleij, A. J. & van Bergen an Henegouwen, P. M. Epidermal growth factor induces ubiquitination of Eps15. J. Biol. Chem. 272, 14013-14016 (1997).
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 14013-14016
-
-
Van Delft, S.1
Govers, R.2
Strous, G.J.3
Verkleij, A.J.4
Van Bergen an Henegouwen, P.M.5
-
55
-
-
0033521670
-
Identification of a novel ubiquitin conjugation motif, required for ligand-induced internalization of the growth hormone receptor
-
Govers, R., ten Broeke, T., van Kerkhof, P., Schwartz, A. L. & Strous, G. J. Identification of a novel ubiquitin conjugation motif, required for ligand-induced internalization of the growth hormone receptor. EMBO J. 18, 28-36 (1999).
-
(1999)
EMBO J.
, vol.18
, pp. 28-36
-
-
Govers, R.1
Ten Broeke, T.2
Van Kerkhof, P.3
Schwartz, A.L.4
Strous, G.J.5
-
56
-
-
0035854827
-
Multiple roles for Rsp5p-dependent ubiquitination at the internalization step of endocytosis
-
Dunn, R. & Hicke, L. Multiple roles for Rsp5p-dependent ubiquitination at the internalization step of endocytosis. J. Biol. Chem. 276, 25974-25981 (2001).
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 25974-25981
-
-
Dunn, R.1
Hicke, L.2
-
57
-
-
0034768447
-
Involvement of the ubiquitin/proteasome system in sorting of the interleukin 2 receptor β chain to late endocytic compartments
-
Rocca, A., Lamaze, C., Subtil, A. & Dautry-Varsat, A. Involvement of the ubiquitin/proteasome system in sorting of the interleukin 2 receptor β chain to late endocytic compartments. Mol. Biol. Cell 12, 1293-1301 (2001).
-
(2001)
Mol. Biol. Cell
, vol.12
, pp. 1293-1301
-
-
Rocca, A.1
Lamaze, C.2
Subtil, A.3
Dautry-Varsat, A.4
-
58
-
-
0032217156
-
c-Cbl/Sli-1 regulates endocytic sorting and ubiquitination of the epidermal growth factor receptor
-
Levkowitz, G. et al. c-Cbl/Sli-1 regulates endocytic sorting and ubiquitination of the epidermal growth factor receptor. Genes Dev. 12, 3663-3674 (1998).
-
(1998)
Genes Dev.
, vol.12
, pp. 3663-3674
-
-
Levkowitz, G.1
-
59
-
-
0032566652
-
Expression of a dominant interfering dynamin mutant in 3T3L1 adipocytes inhibits GLUT4 endocytosis without affecting insulin signaling
-
Kao, A. W., Caresa, B. P., Santeler, S. R. & Pessin, J. E. Expression of a dominant interfering dynamin mutant in 3T3L1 adipocytes inhibits GLUT4 endocytosis without affecting insulin signaling. J. Biol. Chem. 273, 25450-25457 (1998).
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 25450-25457
-
-
Kao, A.W.1
Caresa, B.P.2
Santeler, S.R.3
Pessin, J.E.4
-
60
-
-
0025139326
-
Ligand-induced transformation by a noninternalizing epidermal growth factor receptor
-
Wells, A. et al. Ligand-induced transformation by a noninternalizing epidermal growth factor receptor. Science 247, 962-964 (1990).
-
(1990)
Science
, vol.247
, pp. 962-964
-
-
Wells, A.1
-
61
-
-
0030461226
-
Control of EGF receptor signaling by clathrin-mediated endocytosis
-
Veira, A. V., Lamaze, C. & Schmid, S. L. Control of EGF receptor signaling by clathrin-mediated endocytosis. Science 274, 2086-2089 (1996).
-
(1996)
Science
, vol.274
, pp. 2086-2089
-
-
Veira, A.V.1
Lamaze, C.2
Schmid, S.L.3
-
62
-
-
0027965262
-
Compartmentalization of SHC, GRB2 and mSOS, and hyperphosphorylation of Raf-1 by EGF but not insulin in liver parenchyma
-
Di Guglielmo, G. M., Baass, P. C., Ou, W. J., Posner, B. I. & Bargeron, J. J. Compartmentalization of SHC, GRB2 and mSOS, and hyperphosphorylation of Raf-1 by EGF but not insulin in liver parenchyma. EMBO J. 13, 4269-4277 (1994).
-
(1994)
EMBO J.
, vol.13
, pp. 4269-4277
-
-
Di Guglielmo, G.M.1
Baass, P.C.2
Ou, W.J.3
Posner, B.I.4
Bargeron, J.J.5
-
63
-
-
0033607542
-
Internalized epidermal growth factor receptors participate in the activation of p21 ras in fibroblasts
-
Haugh, J. M., Huang, A. C., Wiley, H. S., Wells, A. & Lauffenburger, D. A. Internalized epidermal growth factor receptors participate in the activation of p21 ras in fibroblasts. J. Biol. Chem. 274, 34350-34360 (1999).
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 34350-34360
-
-
Haugh, J.M.1
Huang, A.C.2
Wiley, H.S.3
Wells, A.4
Lauffenburger, D.A.5
-
64
-
-
0034597554
-
Interaction of EGF receptor and grb2 in living cells visualized by fluorescence resonance energy transfer (FRET) microscopy
-
Sorkin, A., McClure, M., Huang, F. & Carter, R. Interaction of EGF receptor and grb2 in living cells visualized by fluorescence resonance energy transfer (FRET) microscopy. Curr. Biol. 10, 1395-1398 (2000). Together with references 99 and 100, this paper is a good example of FRET studies using in vivo sensors.
-
(2000)
Curr. Biol.
, vol.10
, pp. 1395-1398
-
-
Sorkin, A.1
McClure, M.2
Huang, F.3
Carter, R.4
-
65
-
-
0028021551
-
Phosphorylation of the epidermal growth factor receptor during internalization in A-431 cells
-
Nesterov, A., Lysan, S., Vdovina, I., Nikolsky N. & Fujita, D. J. Phosphorylation of the epidermal growth factor receptor during internalization in A-431 cells. Arch. Biochem. Biophys. 313, 351-359 (1994).
-
(1994)
Arch. Biochem. Biophys.
, vol.313
, pp. 351-359
-
-
Nesterov, A.1
Lysan, S.2
Vdovina, I.3
Nikolsky, N.4
Fujita, D.J.5
-
66
-
-
0033544953
-
Dynamin is required for the activation of mitogen-activated protein (MAP) kinase by MAP kinase kinase
-
Kranenburg, O., Verlaan, I. & Moolenaar, W. H. Dynamin is required for the activation of mitogen-activated protein (MAP) kinase by MAP kinase kinase. J. Biol. Chem. 274, 35301-35304 (1999).
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 35301-35304
-
-
Kranenburg, O.1
Verlaan, I.2
Moolenaar, W.H.3
-
67
-
-
0034703049
-
Intersectin can regulate the Ras/MAP kinase pathway independent of its role in endocytosis
-
Tong, X. K., Hussain, N. K., Adams, A. G., O'Bryan, J. P. & McPherson, P. S. Intersectin can regulate the Ras/MAP kinase pathway independent of its role in endocytosis. J. Biol. Chem. 275, 29894-29899 (2000).
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 29894-29899
-
-
Tong, X.K.1
Hussain, N.K.2
Adams, A.G.3
O'Bryan, J.P.4
McPherson, P.S.5
-
68
-
-
0034711334
-
Signal transduction. An arresting start for MAPK
-
Pouyssegur, J. Signal transduction. An arresting start for MAPK. Science 290, 1515-1518 (2000).
-
(2000)
Science
, vol.290
, pp. 1515-1518
-
-
Pouyssegur, J.1
-
69
-
-
0034689003
-
β-arrestin-dependent and endocytosis of proteinase-activated receptor 2 is required for intracellular targeting of activated ERK1/2
-
DeFea, K. A. et al. β-arrestin-dependent and endocytosis of proteinase-activated receptor 2 is required for intracellular targeting of activated ERK1/2. J. Cell Biol. 148, 1267-1281 (2000).
-
(2000)
J. Cell Biol.
, vol.148
, pp. 1267-1281
-
-
DeFea, K.A.1
-
70
-
-
0034711397
-
β-arrestin 2: A receptor-regulated MAPK scaffold for the activation of JNK3
-
McDonald, P. H. et al. β-arrestin 2: a receptor-regulated MAPK scaffold for the activation of JNK3. Science 290, 1574-1577 (2000).
-
(2000)
Science
, vol.290
, pp. 1574-1577
-
-
McDonald, P.H.1
-
71
-
-
0034255428
-
Cell surface Trk receptors mediate NGF-induced survival while internalized receptors regulate NGF-induced differentiation
-
Zhang, Y., Moheban, D. B., Conway, B. R., Bhattacharyya, A. & Segal, R. A. Cell surface Trk receptors mediate NGF-induced survival while internalized receptors regulate NGF-induced differentiation. J. Neurosci. 20, 5671-5678 (2000).
-
(2000)
J. Neurosci.
, vol.20
, pp. 5671-5678
-
-
Zhang, Y.1
Moheban, D.B.2
Conway, B.R.3
Bhattacharyya, A.4
Segal, R.A.5
-
72
-
-
0033776498
-
Role of phosphoinositide 3-kinase and endocoytosis in nerve growth factor-induced extracellular signal-regulated kinase activation via Ras and Rap 1
-
York, R. D. et al. Role of phosphoinositide 3-kinase and endocoytosis in nerve growth factor-induced extracellular signal-regulated kinase activation via Ras and Rap1. Mol. Cell. Biol. 20, 8069-8083 (2000).
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 8069-8083
-
-
York, R.D.1
-
73
-
-
0033695838
-
Spatially and functionally distinct roles of the Pl3-K effector pathway during NGF signaling in sympathetic neurons
-
Kuruvilla, R., Ye, H. & Ginty, D. D. Spatially and functionally distinct roles of the Pl3-K effector pathway during NGF signaling in sympathetic neurons. Neuron 27, 499-512 (2000).
-
(2000)
Neuron
, vol.27
, pp. 499-512
-
-
Kuruvilla, R.1
Ye, H.2
Ginty, D.D.3
-
74
-
-
0029061444
-
NGF-stimulated retrograde transport of trkA in the mammalian nervous system
-
Ehlers, M. D., Kaplan, D. R., Price, D. L. & Koliatsos, V. E. NGF-stimulated retrograde transport of trkA in the mammalian nervous system. J. Cell Biol. 130, 149-156 (1995).
-
(1995)
J. Cell Biol.
, vol.130
, pp. 149-156
-
-
Ehlers, M.D.1
Kaplan, D.R.2
Price, D.L.3
Koliatsos, V.E.4
-
75
-
-
0030985451
-
A signaling organelle containing the nerve growth factor-activated receptor tyrosine kinase, TrkA
-
Grimes, M. L., Beattle, E. & Mobley, W. C. A signaling organelle containing the nerve growth factor-activated receptor tyrosine kinase, TrkA. Proc. Natl Acad. Sci. USA 94, 9909-9914 (1997).
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 9909-9914
-
-
Grimes, M.L.1
Beattle, E.2
Mobley, W.C.3
-
76
-
-
10544248585
-
Endocytosis of activated TrkA: Evidence that nerve growth factor induces formation of signaling endosomes
-
Grimes, M. L. et al. Endocytosis of activated TrkA: evidence that nerve growth factor induces formation of signaling endosomes, J. Neurosci. 16, 7950-7964 (1996).
-
(1996)
J. Neurosci.
, vol.16
, pp. 7950-7964
-
-
Grimes, M.L.1
-
77
-
-
0033216248
-
Characterization of an NGF-P-TrkA retrograde-signaling complex and age-dependent regulation of TrkA phosphorylation in sympathetic neurons
-
Tsui-Pierchala, B. A. & Ginty, D. D. Characterization of an NGF-P-TrkA retrograde-signaling complex and age-dependent regulation of TrkA phosphorylation in sympathetic neurons. J. Neurosci. 19, 8207-8218 (1999).
-
(1999)
J. Neurosci.
, vol.19
, pp. 8207-8218
-
-
Tsui-Pierchala, B.A.1
Ginty, D.D.2
-
78
-
-
0030801304
-
An NGF-TrkA-mediated retrograde signal to transcription factor CREB in sympathetic neurons
-
Riccio, A., Pierchala, B. A., Ciarallo, C. L. & Ginty, D. D. An NGF-TrkA-mediated retrograde signal to transcription factor CREB in sympathetic neurons. Science 277, 1097-1100 (1997).
-
(1997)
Science
, vol.277
, pp. 1097-1100
-
-
Riccio, A.1
Pierchala, B.A.2
Ciarallo, C.L.3
Ginty, D.D.4
-
79
-
-
0030861966
-
Rapid retrograde tyrosine phosphorylation of trkA and other proteins in rat sympathetic neurons in compartmented cultures
-
Senger, D. L. & Campenot, R. B. Rapid retrograde tyrosine phosphorylation of trkA and other proteins in rat sympathetic neurons in compartmented cultures. J. Cell Biol. 138, 411-421 (1997).
-
(1997)
J. Cell Biol.
, vol.138
, pp. 411-421
-
-
Senger, D.L.1
Campenot, R.B.2
-
80
-
-
0037172658
-
Sonic hedgehog induces the segregation of patched and smoothened in endosomes
-
Incardona, J. P., Gruenberg, J. & Roelink, H. Sonic hedgehog induces the segregation of patched and smoothened in endosomes. Curr. Biol. 12, 983-995 (2002). An analysis of the trafficking of Ptc and Smo in the presence and absence of ligand. These authors propose an interesting hypothesis, whereby ligand binding to Ptc diverts its trafficking towards degradation and thereby frees the trafficking of Smo towards a compartment that is permissive for its signalling activity.
-
(2002)
Curr. Biol.
, vol.12
, pp. 983-995
-
-
Incardona, J.P.1
Gruenberg, J.2
Roelink, H.3
-
81
-
-
0035577854
-
Hedgehog signaling in animal development: Paradigms and principles
-
Ingham, P. W. & McMahon, A. P. Hedgehog signaling in animal development: paradigms and principles. Genes Dev. 15, 3059-3087 (2001).
-
(2001)
Genes Dev.
, vol.15
, pp. 3059-3087
-
-
Ingham, P.W.1
McMahon, A.P.2
-
82
-
-
0031685620
-
TGF-β signal transduction
-
Massagué, J. TGF-β signal transduction. Annu. Rev. Biochem. 67, 753-791 (1998).
-
(1998)
Annu. Rev. Biochem.
, vol.67
, pp. 753-791
-
-
Massagué, J.1
-
83
-
-
0032428684
-
SARA, a FYVE domain protein that recruits Smad2 to the TGFβ receptor
-
Tsukazaki, T., Chiang, T. A., Davidson, A. F., Attisano, L. & Wrana, J. L. SARA, a FYVE domain protein that recruits Smad2 to the TGFβ receptor. Cell 95, 779-791 (1998). The first report of SARA as a TGF-β signalling mediator. It shows that SARA functions as an adaptor for the receptor and the transcription factor Smad2.
-
(1998)
Cell
, vol.95
, pp. 779-791
-
-
Tsukazaki, T.1
Chiang, T.A.2
Davidson, A.F.3
Attisano, L.4
Wrana, J.L.5
-
84
-
-
0035793903
-
Structural mechanism of endosome docking by the FYVE domain
-
Kutateladze, T. & Overduln, M. Structural mechanism of endosome docking by the FYVE domain. Science 291, 1793-1796 (2001).
-
(2001)
Science
, vol.291
, pp. 1793-1796
-
-
Kutateladze, T.1
Overduln, M.2
-
85
-
-
0035424239
-
The role of phosphoinositides in membrane transport
-
Simonsen, A., Wurmser, A. E., Emr, S. D. & Stenmark, H. The role of phosphoinositides in membrane transport. Curr. Opin. Cell Biol. 13, 485-492 (2001).
-
(2001)
Curr. Opin. Cell Biol.
, vol.13
, pp. 485-492
-
-
Simonsen, A.1
Wurmser, A.E.2
Emr, S.D.3
Stenmark, H.4
-
86
-
-
0034282751
-
Localization of phosphatidylinositol 3-phosphate in yeast and mammalian cells
-
Gillooly, D. J. et al. Localization of phosphatidylinositol 3-phosphate in yeast and mammalian cells. EMBO J. 19, 4577-4588 (2000).
-
(2000)
EMBO J.
, vol.19
, pp. 4577-4588
-
-
Gillooly, D.J.1
-
87
-
-
0035871081
-
Cellular functions of phosphatidylinositol 3-phosphate and FYVE domain proteins
-
Gillooly, D. J., Simonsen, A. & Stenmark, H. Cellular functions of phosphatidylinositol 3-phosphate and FYVE domain proteins. Biochem. J. 355, 249-258 (2001).
-
(2001)
Biochem. J.
, vol.355
, pp. 249-258
-
-
Gillooly, D.J.1
Simonsen, A.2
Stenmark, H.3
-
88
-
-
0033515592
-
Phosphoinositide 3-kinases and their FYVE domain-containing effectors as regulators of vacuolar/lysosomal membrane trafficking pathways
-
Wurmser, A. E., Gary, J. D. & Emr, S. D. Phosphoinositide 3-kinases and their FYVE domain-containing effectors as regulators of vacuolar/lysosomal membrane trafficking pathways. J. Biol. Chem. 274, 9129-9132 (1999).
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 9129-9132
-
-
Wurmser, A.E.1
Gary, J.D.2
Emr, S.D.3
-
89
-
-
0037169336
-
Hrs regulates endosome membrane invagination and tyrosine kinase receptor signaling in Drosophila
-
Lloyd, T. E. et al. Hrs regulates endosome membrane invagination and tyrosine kinase receptor signaling in Drosophila. Cell 108, 261-269 (2002).
-
(2002)
Cell
, vol.108
, pp. 261-269
-
-
Lloyd, T.E.1
-
90
-
-
0035801478
-
Hrs recruits clathrin to early endosomes
-
Raiborg, C., Bache, K. G., Mehlum, A., Stang, E. & Stenmark, H. Hrs recruits clathrin to early endosomes. EMBO J. 20, 5008-5021 (2001).
-
(2001)
EMBO J.
, vol.20
, pp. 5008-5021
-
-
Raiborg, C.1
Bache, K.G.2
Mehlum, A.3
Stang, E.4
Stenmark, H.5
-
91
-
-
0036094538
-
Hrs sorts ubiquitinated proteins into clathrin-coated microdomains of early endosomes
-
Raiborg, C. et al. Hrs sorts ubiquitinated proteins into clathrin-coated microdomains of early endosomes. Nature Cell Biol. 4, 394-398 (2002).
-
(2002)
Nature Cell Biol.
, vol.4
, pp. 394-398
-
-
Raiborg, C.1
-
92
-
-
0034462833
-
Hgs (Hrs), a FYVE domain protein, is involved in Smad signaling through cooperation with SARA
-
Miura, S. et al. Hgs (Hrs), a FYVE domain protein, is involved in Smad signaling through cooperation with SARA. Mol. Cell. Biol. 20, 9346-9355 (2000).
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 9346-9355
-
-
Miura, S.1
-
93
-
-
0037144841
-
TGF-β receptor internalization into EEA1-enriched early endosomes: Role in signaling to Smad2
-
Hayes, S., Chawla, A. & Corvera, S. TGF-β receptor internalization into EEA1-enriched early endosomes: role in signaling to Smad2. J. Cell Biol. 158, 1239-1249 (2002).
-
(2002)
J. Cell Biol.
, vol.158
, pp. 1239-1249
-
-
Hayes, S.1
Chawla, A.2
Corvera, S.3
-
94
-
-
0036201871
-
The FYVE domain in Smad anchor for receptor activation (SARA) is sufficient for localization of SARA in early endosomes and regulates TGF-β/Smad signalling
-
Itoh, F. et al. The FYVE domain in Smad anchor for receptor activation (SARA) is sufficient for localization of SARA in early endosomes and regulates TGF-β/Smad signalling. Genes Cells 7, 321-331 (2002).
-
(2002)
Genes Cells
, vol.7
, pp. 321-331
-
-
Itoh, F.1
-
95
-
-
0037124028
-
Early endosomal regulation of Smad-dependent signaling in endothelial cells
-
Panopoulou, E. et al. Early endosomal regulation of Smad-dependent signaling in endothelial cells. J. Biol. Chem. 277, 18046-18052 (2002). Together with references 93 and 94, this study analyses the subcellular localization of SARA to the early endosome. It shows that localization of SARA to the endosome is essential to mediate TGF-β signalling.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 18046-18052
-
-
Panopoulou, E.1
-
96
-
-
0036272313
-
Internalization-dependent and -independent requirements for transforming growth factor β receptor signaling via the Smad pathway
-
Penheiter, S. G. et al. Internalization-dependent and -independent requirements for transforming growth factor β receptor signaling via the Smad pathway. Mol. Cell. Biol. 22. 4750-4759 (2002). This paper shows that the receptor-SARA-Smad2 complex forms at the plasma membrane, but that the SARA-mediated phosphorylation of the transcription factor by the receptor requires internalization.
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 4750-4759
-
-
Penheiter, S.G.1
-
97
-
-
0034253480
-
The nuclear import function of Smad2 is masked by SARA and unmasked by TGF-dependent phosphorylation
-
Xu, L., Chen, Y. G. & Massague, J. The nuclear import function of Smad2 is masked by SARA and unmasked by TGF-dependent phosphorylation. Nature Cell Biol. 2, 559-562 (2000). This study shows that Smad2 by itself can be imported into the nucleus, but that SARA retains it in the cytoplasm. On phosphorylation, Smad2 is released from SARA and moves to the nucleus.
-
(2000)
Nature Cell Biol.
, vol.2
, pp. 559-562
-
-
Xu, L.1
Chen, Y.G.2
Massague, J.3
-
98
-
-
0034711405
-
Quantitative imaging of lateral ErbB1 receptor signal propagation in the plasma membrane
-
Verveer, P. J., Wouters, F. S., Reynolds, A. F. & Bastiaens, P. I. Quantitative imaging of lateral ErbB1 receptor signal propagation in the plasma membrane. Science 290, 1567-1570 (2000).
-
(2000)
Science
, vol.290
, pp. 1567-1570
-
-
Verveer, P.J.1
Wouters, F.S.2
Reynolds, A.F.3
Bastiaens, P.I.4
-
99
-
-
0035903217
-
A pair of fluorescent resonance energy transfer-based probes for tyrosine phosphorylation of the CrkII adaptor protein in vivo
-
Kurokawa, K. et al. A pair of fluorescent resonance energy transfer-based probes for tyrosine phosphorylation of the CrkII adaptor protein in vivo. J. Biol. Chem 276, 31305-31310 (2001).
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 31305-31310
-
-
Kurokawa, K.1
-
100
-
-
0035963331
-
Spatio-temporal images of growth-factor-induced activation of Ras and Rap1
-
Mochizuki, N. et al. Spatio-temporal images of growth-factor-induced activation of Ras and Rap1. Nature 411, 1065-1068 (2001).
-
(2001)
Nature
, vol.411
, pp. 1065-1068
-
-
Mochizuki, N.1
|