Interaction of EGF receptor and Grb2 in living cells visualized by fluorescence resonance energy transfer (FRET) microscopy

Current Biology

Volumn 10, Issue 21, 2000, Pages 1395-1398

  Sorkin, Alexander ^a   McClure, Maria ^a   Huang, Fangtian ^a   Carter, Royston ^a  

^a UNIVERSITY OF COLORADO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0034597554     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-9822(00)00785-5     Document Type: Article

References (18)

1. The SH2 and SH3 domains of mammalian Grb2 couple the EGF receptor to the Ras activator mSos1
2. Guanine-nucleotide-releasing factor hSos1 binds to Grb2 and links receptor tyrosine kinases to Ras signalling
3. Engineering green fluorescent protein for improved brightness, longer wavelengths and fluorescence resonance energy transfer
4. Endocytosis of functional epidermal growth factor receptor-green fluorescent protein chimera
5. Quantitative fluorescence resonance energy transfer measurements using fluorescence microscopy
6. Grb2 and its apoptotic isoform Grb3-3 associate with heterogeneous nuclear ribonucleoprotein C, and these interactions are modulated by poly(U) RNA
7. SH3 domains direct cellular localization of signaling molecules
8. Dimerization of internalized growth factor receptors
9. Grb2/Ash binds directly to tyrosines 1068 and 1086 and indirectly to tyrosine 1148 of activated human epidermal growth factor receptors in intact cells
10. Compartmentalized signal transduction by receptor tyrosine kinases
11. Compartmentalization of SHC, GRB2 and mSOS, and hyperphosphorylation of Raf-1 by EGF but not insulin in liver parenchyma
12. Control of EGF receptor signaling by clathrin-mediated endocytosis
13. Role of arrestins in endocytosis and signaling of α2-adrenergic receptor subtypes
14. Dynamin is required for the activation of mitogen-activated protein (MAP) kinase by MAP kinase kinase
15. Fluorescence lifetime imaging of receptor tyrosine kinase activity in cells
16. Cyclic AMP-dependent protein kinase binding to A-kinase anchoring proteins in living cells by fluorescence resonance energy transfer of green fluorescent protein fusion proteins
17. 2+ based on green fluorescent proteins and calmodulin
18. Interactions of clathrin assembly lymhoid myeloid (CALM) protein with clathrin and its impact on endocytosis