Discovery and in vivo evaluation of new melanocortin-4 receptor-selective peptides

Peptides

Volumn 24, Issue 2, 2003, Pages 271-280

  Nijenhuis, Wouter A J ^a   Kruijtzer, John A W ^b   Wanders, Nienke ^a   Vrinten, Dorien H ^a   Garner, Keith M ^a   Schaaper, Wim M M ^c   Meloen, Rob H ^c   Gispen, Willem Hendrik ^a   Liskamp, Rob M ^b   Adan, Roger A H ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b UTRECHT UNIVERSITY   (Netherlands)

^c WAGENINGEN UNIVERSITY   (Netherlands)

Author keywords

Grooming; Melanocortin receptor; Neuropathic pain; PEPSCAN; Selective ligand

Indexed keywords

ACETYLGLYCYLGLYCYLLYSYL DEXTRO PHENYLALANYLARGINYLTRYPTOPHYLGLYCINAMIDE; ACETYLHISTIDYL DEXTRO PHENYLALANYLARGINYLTRYPTOPHANAMIDE; ACETYLLYSYL DEXTRO PHENYLALANYLARGINYLTRYPTOPHANAMIDE; ACETYLNORLEUCYLGLYCYLALANYL DEXTRO PHENYLALANYLARGINYLTRYPTOPHYLGLYCINAMIDE; ACETYLNORLEUCYLGLYCYLARGINYL DEXTRO PHENYLALANYLARGINYLTRYPTOPHYLGLYCINAMIDE; ACETYLNORLEUCYLGLYCYLLYSYL DEXTRO PHENYLALANYLARGINYLTRYPTOPHYLGLYCINAMIDE; MELANOCORTIN 3 RECEPTOR; MELANOCORTIN 4 RECEPTOR; MELANOCORTIN 5 RECEPTOR; N ACETYL ALPHA INTERMEDIN[4-10]CYCLO[4 NORLEUCINE 5 ASPARTIC ACID 7 [3 (2 NAPHTHYL)ALANINE] 10 LYSINAMIDE]; PEPTIDE DERIVATIVE; UNCLASSIFIED DRUG;

ALLODYNIA; ANIMAL BEHAVIOR; ANIMAL MODEL; ARTICLE; BINDING AFFINITY; BLOOD BRAIN BARRIER; CONTROLLED STUDY; DOSE RESPONSE; DRUG POTENCY; DRUG SCREENING; DRUG SELECTIVITY; DRUG SYNTHESIS; GROOMING; HUMAN; HUMAN CELL; IN VIVO STUDY; MALE; NEUROPATHIC PAIN; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; RAT; SCREENING;

EID: 0037302373     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0196-9781(03)00032-9     Document Type: Article

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