Analogs of MTII, lactam derivatives of α-melanotropin, modified at the N-terminus, and their selectivity at human melanocortin receptors 3, 4, and 5

Biochemical and Biophysical Research Communications

Volumn 261, Issue 1, 1999, Pages 209-213

  Bednarek, Maria A ^a   Macneil, Tanya ^a   Kalyani, Rubana N ^a   Tang, Rui ^a   Van Der Ploeg, Lex H T ^a   Weinberg, David H ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Binding affinity; cAMP accumulation assay; Melanocortin receptor; Melanotropin; Proline scan

Indexed keywords

ALPHA INTERMEDIN; MELANOCORTIN RECEPTOR; PROLINE;

AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DRUG POTENCY; HYDROPHILICITY; HYDROPHOBICITY; NONHUMAN; PRIORITY JOURNAL; RECEPTOR AFFINITY;

ANIMALIA;

EID: 0033595130     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.1999.0981     Document Type: Article

References (19)

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18. 6, ]MTII has been recently reported (abstract) by V. J. Hruby and co-workers at the 217th National Meeting of American Chemical Society, Anaheim, California, March 21-25, 1999.
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