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Volumn 40, Issue 14, 1997, Pages 2133-2139

Discovery of prototype peptidomimetic agonists at the human melanocortin receptors MC1R and MC4R

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERMEDIN; ALPHA INTERMEDIN DERIVATIVE; ALPHA INTERMEDIN[4 NORLEUCINE 7 DEXTRO PHENYLALANINE]; HORMONE RECEPTOR; HORMONE RECEPTOR STIMULATING AGENT; MELANOCORTIN RECEPTOR; MELANOCORTIN RECEPTOR STIMULATING AGENT; PROOPIOMELANOCORTIN; RECEPTOR SUBTYPE; TETRAPEPTIDE; TRIPEPTIDE; UNCLASSIFIED DRUG;

EID: 0030787858     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm960840h     Document Type: Article
Times cited : (94)

References (34)
  • 1
    • 84924830720 scopus 로고
    • In Vitro Bioassay for the Melanocyte Stimulating Hormone
    • Shizume, K.; Lerner, A. B.; Fitzpatrick, T. B. In Vitro Bioassay for the Melanocyte Stimulating Hormone. Endocrinology 1954, 54, 533-560.
    • (1954) Endocrinology , vol.54 , pp. 533-560
    • Shizume, K.1    Lerner, A.B.2    Fitzpatrick, T.B.3
  • 2
    • 0014788807 scopus 로고
    • Evidence for Separate Receptors for Melanophore Stimulating Hormone and Catecholamine Regulation of Cyclic AMP in the Control of Melanophore Responses
    • Goldman, J. M.; Hadley, M. E. Evidence for Separate Receptors for Melanophore Stimulating Hormone and Catecholamine Regulation of Cyclic AMP in the Control of Melanophore Responses. Br. J. Pharmacol. 1970, 39, 160-166.
    • (1970) Br. J. Pharmacol. , vol.39 , pp. 160-166
    • Goldman, J.M.1    Hadley, M.E.2
  • 3
    • 84909526988 scopus 로고
    • Receptor-Specific Calcium Requirement for Melanophore-Stimulating Hormone
    • Riley, V., Eds.; S. Karger: Basel
    • Vesely, D. L.; Hadley, M. E. Receptor-Specific Calcium Requirement for Melanophore-Stimulating Hormone. In Pigment Cell: Unique Properties of Melanocytes; Riley, V., Eds.; S. Karger: Basel, 1976; Vol. 3, pp 265-274.
    • (1976) Pigment Cell: Unique Properties of Melanocytes , vol.3 , pp. 265-274
    • Vesely, D.L.1    Hadley, M.E.2
  • 6
    • 0000448866 scopus 로고
    • 4-Norleucine, 7-D-Phenylalanine-α-Melanocyte-Stimulating Hormone: A Highly Potent α-Melanotropin with Ultra Long Biological Activity
    • Sawyer, T. K.; Sanfillippo, P. J.; Hruby, V. J.; Engel, M. H.; Heward, C. B.; Burnett, J. B.; Hadley, M. E. 4-Norleucine, 7-D-Phenylalanine-α-Melanocyte-Stimulating Hormone: A Highly Potent α-Melanotropin with Ultra Long Biological Activity. Proc. Natl. Acad. Sci. U.S.A. 1980, 77, 5754-5758.
    • (1980) Proc. Natl. Acad. Sci. U.S.A. , vol.77 , pp. 5754-5758
    • Sawyer, T.K.1    Sanfillippo, P.J.2    Hruby, V.J.3    Engel, M.H.4    Heward, C.B.5    Burnett, J.B.6    Hadley, M.E.7
  • 7
    • 0019890250 scopus 로고
    • Calcium-Dependent Prolonged Effects on Melanophores of [4-Norleucine, 7-D-Phenylalanine]-α-Melanotropin
    • Hadley, M. E.; Anderson, B.; Heward, C. B.; Sawyer, T. K.; Hruby, V. J. Calcium-Dependent Prolonged Effects on Melanophores of [4-Norleucine, 7-D-Phenylalanine]-α-Melanotropin. Science 1981, 213, 1025-1027.
    • (1981) Science , vol.213 , pp. 1025-1027
    • Hadley, M.E.1    Anderson, B.2    Heward, C.B.3    Sawyer, T.K.4    Hruby, V.J.5
  • 12
    • 0026731363 scopus 로고
    • Molecular Cloning and Expression of the Human Melanocyte Stimulating Hormone Receptor cDNA
    • Chhajlani, V.; Wikberg, J. E. S. Molecular Cloning and Expression of the Human Melanocyte Stimulating Hormone Receptor cDNA. FEBS Lett 1992, 309, 417-420.
    • (1992) FEBS Lett. , vol.309 , pp. 417-420
    • Chhajlani, V.1    Wikberg, J.E.S.2
  • 13
    • 0026800892 scopus 로고
    • The Cloning of a Family of Genes that Encode the Melanocortin Receptors
    • Mountjoy, K. G.; Robbins, L. S.; Mortrud, M. T.; Cone, R. D. The Cloning of a Family of Genes that Encode the Melanocortin Receptors. Science 1992, 257, 1248-1251.
    • (1992) Science , vol.257 , pp. 1248-1251
    • Mountjoy, K.G.1    Robbins, L.S.2    Mortrud, M.T.3    Cone, R.D.4
  • 18
    • 0030614331 scopus 로고    scopus 로고
    • Role of Melanocortinergic Neurons in Feeding and the agouti Obesity Syndrome
    • Fan, W.; Boston, B. A.; Kesterson, R. A.; Hruby, V. J.; Cone, V. D. Role of Melanocortinergic Neurons in Feeding and the agouti Obesity Syndrome. Nature 1997, 385, 165-168.
    • (1997) Nature , vol.385 , pp. 165-168
    • Fan, W.1    Boston, B.A.2    Kesterson, R.A.3    Hruby, V.J.4    Cone, V.D.5
  • 20
    • 0027049534 scopus 로고
    • Molecular Characterization of the Mouse Agouti Locus
    • Bultman, S. J.; Michaud, E. J.; Woychick, R. P. Molecular Characterization of the Mouse Agouti Locus. Cell 1992, 71, 1195-1204.
    • (1992) Cell , vol.71 , pp. 1195-1204
    • Bultman, S.J.1    Michaud, E.J.2    Woychick, R.P.3
  • 23
    • 0011949673 scopus 로고    scopus 로고
    • Molecular Model of the G-Protein Coupled Melanocortin Receptor, hMC1R, and Proposed Interactions with α-MSH Peptides
    • Kaumaya, P. T. P., Hodges, R. S., Eds.; Mayflower Scientific Ltd: Kingswinford, England
    • Haskell-Luevano, C.; Sawyer, T. K.; Hruby, V. J. Molecular Model of the G-Protein Coupled Melanocortin Receptor, hMC1R, and Proposed Interactions with α-MSH Peptides. In Peptides, Chemistry, Structure and Biology; Kaumaya, P. T. P., Hodges, R. S., Eds.; Mayflower Scientific Ltd: Kingswinford, England, 1996; pp 378-379.
    • (1996) Peptides, Chemistry, Structure and Biology , pp. 378-379
    • Haskell-Luevano, C.1    Sawyer, T.K.2    Hruby, V.J.3
  • 24
    • 0027506471 scopus 로고
    • The Probable Arrangement of the Helices in G Protein-Coupled Receptors
    • Baldwin J. M. The Probable Arrangement of the Helices in G Protein-Coupled Receptors. EMBO J. 1993, 12, 1693-1703.
    • (1993) EMBO J. , vol.12 , pp. 1693-1703
    • Baldwin, J.M.1
  • 25
    • 0029976454 scopus 로고    scopus 로고
    • Receptor Conformation Induction Versus Selection: All Part of the Same Energy Landscape
    • Kenakin, T. Receptor Conformation Induction Versus Selection: All Part of the Same Energy Landscape. Trends Pharmacol. Sci. 1996, 17, 190-191.
    • (1996) Trends Pharmacol. Sci. , vol.17 , pp. 190-191
    • Kenakin, T.1
  • 26
    • 0029061611 scopus 로고
    • Agonist-Receptor Efficacy I: Mechanisms of Efficacy and Receptor Promiscuity
    • Kenakin, T. Agonist-Receptor Efficacy I: Mechanisms of Efficacy and Receptor Promiscuity. Trends Pharmacol. Sci. 1995, 16, 188-192.
    • (1995) Trends Pharmacol. Sci. , vol.16 , pp. 188-192
    • Kenakin, T.1
  • 27
    • 0029054965 scopus 로고
    • Agonist-Receptor Efficacy II: Atonist Trafficking of Receptor Signals
    • Kenakin, T. Agonist-Receptor Efficacy II: Atonist Trafficking of Receptor Signals. Trends Pharmacol. Sci. 1995, 16, 232-238.
    • (1995) Trends Pharmacol. Sci. , vol.16 , pp. 232-238
    • Kenakin, T.1
  • 29
    • 11944268922 scopus 로고
    • Molecular Mechanism of Action of Non-peptide Ligands for Peptide Receptors
    • Schwartz, T. W.; Gether, U.; Schambye, H. T.; Hjorth, S. A. Molecular Mechanism of Action of Non-peptide Ligands for Peptide Receptors. Curr. Pharm. Des. 1995, 1, 325-342.
    • (1995) Curr. Pharm. Des. , vol.1 , pp. 325-342
    • Schwartz, T.W.1    Gether, U.2    Schambye, H.T.3    Hjorth, S.A.4
  • 30
    • 0029873472 scopus 로고    scopus 로고
    • Construction of a High Affinity Zinc Switch in the k-Opioid Receptor
    • Thristrup, K.; Elling, C. E.; Hjorth, S. A.; Schwartz, T. W. Construction of a High Affinity Zinc Switch in the k-Opioid Receptor. J. Biol. Chem. 1996, 271, 7875-7878.
    • (1996) J. Biol. Chem. , vol.271 , pp. 7875-7878
    • Thristrup, K.1    Elling, C.E.2    Hjorth, S.A.3    Schwartz, T.W.4
  • 31
    • 0028800729 scopus 로고
    • Conversion of Antagonist-Binding Site to Metal-Ion Site in the Tachykinin NK-1 Receptor
    • Elling, C. E.; Nielsen, S. M.; Schwartz, T. W. Conversion of Antagonist-Binding Site to Metal-Ion Site in the Tachykinin NK-1 Receptor. Nature 1995, 374, 74-77.
    • (1995) Nature , vol.374 , pp. 74-77
    • Elling, C.E.1    Nielsen, S.M.2    Schwartz, T.W.3
  • 32
    • 0028799933 scopus 로고
    • Topographical Modifications of Melanotropin Peptide Analogues with β-Methyltryptophan Isomers at Position 9 Leads to Differential Potencies and Prolonged Biological Activities
    • Haskell-Luevano, C.; Boteju, L. W.; Miwa, H.; Dickinson, C.; Gantz, I.; Yamada, T.; Hadley, M. E.; Hruby, V. J. Topographical Modifications of Melanotropin Peptide Analogues with β-Methyltryptophan Isomers at Position 9 Leads to Differential Potencies and Prolonged Biological Activities. J. Med. Chem. 1995, 38, 4720-4729.
    • (1995) J. Med. Chem. , vol.38 , pp. 4720-4729
    • Haskell-Luevano, C.1    Boteju, L.W.2    Miwa, H.3    Dickinson, C.4    Gantz, I.5    Yamada, T.6    Hadley, M.E.7    Hruby, V.J.8
  • 33
    • 0023606861 scopus 로고
    • Specific Receptors for α-Melanocyte-Stimulating Hormone are Widely Distributed in Tissues of Rodents
    • Tatro, J. B.; Reichlin, S. Specific Receptors for α-Melanocyte-Stimulating Hormone are Widely Distributed in Tissues of Rodents. Endocrinology 1987, 121, 1900-1907.
    • (1987) Endocrinology , vol.121 , pp. 1900-1907
    • Tatro, J.B.1    Reichlin, S.2
  • 34
    • 0028845059 scopus 로고
    • Nonlinear Regression Using Spreadsheets
    • Bowen, W. P.; Jerman, J. C. Nonlinear Regression Using Spreadsheets. Trends Pharmacol. Sci. 1995, 16, 413-417.
    • (1995) Trends Pharmacol. Sci. , vol.16 , pp. 413-417
    • Bowen, W.P.1    Jerman, J.C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.