Functional recovery after central infusion of α-melanocyte-stimulating hormone in rats with spinal cord contusion injury

Journal of Neurotrauma

Volumn 16, Issue 4, 1999, Pages 323-331

  Lankhorst, Alex J ^a   Duis, Simone E J ^a   Laak, Mariël P Ter ^a   Joosten, Elbert A J ^b   Hamers, Frank P T ^a   Gispen, Willem Hendrik ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

Functional recovery; Intrathecal administration; Melanocortins; Motor evoked potentials; Spinal cord injury; Spontaneous recovery; MSH

Indexed keywords

ALPHA INTERMEDIN; CORTICOTROPIN; MELANOCORTIN;

ARTICLE; CISTERNA MAGNA; CONTROLLED STUDY; CONTUSION; DOSE CALCULATION; DRUG EFFECT; ELECTROPHYSIOLOGY; EVOKED MUSCLE RESPONSE; FEMALE; INTRATHECAL DRUG ADMINISTRATION; LOCOMOTION; NERVE FIBER REGENERATION; NONHUMAN; PERIPHERAL NERVE INJURY; RAT; SPINAL CORD INJURY;

EID: 0032954911     PISSN: 08977151     EISSN: None     Source Type: Journal    
DOI: 10.1089/neu.1999.16.323     Document Type: Article

References (41)

1. AZMITIA, E.C., and DEKLOET, E.R. (1987). ACTH neuropeptide stimulation of serotonergic neuronal maturation in tissue culture: modulation by hippocampal cells. Prog. Brain Res. 72, 311-318.
2. BANKS, W.A., and KASTIN, A.J. (1995). Permeability of the blood-brain barrier to melanocortins. Peptides 16, 1157-1161.
3. BASSO, D.M., BEATTIE, M.S., and BRESNAHAN, J.C. (1995). A sensitive and reliable locomotor rating scale for open field testing in rats. J. Neurotrauma 12, 1-21.
4. BASSO, D.M., BEATTIE, M.S., and BRESNAHAN, J.C. (1996). Graded histological and locomotor outcomes after spinal cord contusion using the NYU weight-drop device versus transaction. Exp. Neurol. 139, 244-256.
5. BENELLI, A., ZANOLI, P., BOTTICELLI, A., and BERTOLINI, A. (1988). [Nle4,D-Phe7]alpha-MSH improves functional recovery in rats subjected to diencephalic hemisection. Eur. J. Pharmacol. 150, 211-219.
6. BIJLSMA, W.A., JENNEKENS, F.G., SCHOTMAN, P., and GISPEN, W.H. (1983). Stimulation by ACTH4-10 of nerve fiber regeneration following sciatic nerve crush. Muscle Nerve 6, 104-112.
7. BIJLSMA, W.A., JENNEKENS, F.G., SCHOTMAN, P., and GISPEN, W.H. (1984). Neurotrophic factors and regeneration in the peripheral nervous system. Psychoneuroendocrinology 9, 199-215.
8. BRACKEN, M.B., SHEPARD, M.J., COLLINS, W.F., et al. (1990). A randomized, controlled trial of methylprednisolone or naloxone in the treatment of acute spinal-cord injury. N. Engl. J. Med. 322, 1405-1411.
9. BREGMAN, B.S., KUNKEL BAGDEN, E., REIER, P.J., DAI, H.N., MCATEE, M., and GAO, D. (1993). Recovery of function after spinal cord injury: mechanisms underlying transplant-mediated recovery of function differ after spinal cord injury in newborn and adult rats. Exp. Neurol. 123, 3-16.
10. CROWE, M.J., BRESNAHAN, J.C., SHUMAN, S.L., MASTERS, J.N., and BEATTIE, M.S. (1997). Apoptosis and delayed degeneration after spinal cord injury in rats and monkeys. Nat. Med. 3, 73-76.
11. DAVAL, J.L., LOUIS, J.C., GERARD, M.J., and VINCENDON, G. (1983). Influence of adrenocorticotropic hormone on the growth of isolated neurons in culture. Neurosci. Lett. 36, 299-304.
12. DAWIRS, R.R., TEUCHERT NOODT, G., and NOSSOLL, M. (1997). Pharmacologically induced neural plasticity in the prefrontal cortex of adult gerbils (Meriones unguiculatus). Eur. J. Pharmacol. 327, 117-123.
13. DE ROTTE, A.A., BOUMAN, H.J., and VAN WIMERSMA GREIDANUS, T.B. (1980). Relationships between alpha-MSH levels in blood and in cerebrospinal fluid. Brain Res. Bull. 5, 375-381.
14. EDWARDS, P.M., KUITERS, R.R., BOER, G.J., and GISPEN, W.H. (1986). Recovery from peripheral nerve transection is accelerated by local application of alpha-MSH by means of microporous Accurel polypropylene tubes. J. Neurol. Sci. 74, 171-176.
15. EDWARDS, P.M., VAN DER ZEE, C.E., VERHAAGEN, J., SCHOTMAN, P., JENNEKENS, F.G., and GISPEN, W.H. (1984). Evidence that the neurotrophic actions of alpha-MSH may derive from its ability to mimick the actions of a peptide formed in degenerating nerve stumps. J. Neurol. Sci. 64, 333-340.
16. FISCHER, M., KAECH, S., KNUTTI, D., and MATUS, A. (1998). Raid actin-based plasticity in dendritic spines. Neuron 20, 847-854.
17. GEHRMANN, J., MATSUMOTO, Y., and KREUTZBERG, G.W. (1995). Microglia: intrinsic immuneffector cell of the brain. Brain Res. Brain Res. Rev. 20, 269-287.
18. GISPEN, W.H., VERHAAGEN, J., and BAR, D. (1994). ACTH/MSH-derived peptides and peripheral nerve plasticity: neuropathies, neuroprotection and repair. Prog. Brain Res. 100, 223-229.
19. GRUNER, J.A. (1992). A monitored contusion model of spinal cord injury in the rat. J. Neurotrauma 9, 123-128.
20. HAYAKAWA, K., SOBUE, G., ITOH, T., and MITSUMA, T. (1994). Nerve growth factor prevents neurotoxic effects of Cisplatin, Vincristine and Taxol, on adult rat sympathetic ganglion explants in vitro. Life Sci. 55, 519-525.
21. JOOSTEN, E.A.J., MAJEVSKA, B., HOUWELING, D.A., BAR, P.R., and GISPEN, W.H. (1999). Alpha-melanocyte stimulating hormone promotes regrowth of injured axons in the adult rat spinal cord. J. Neurotrauma 16, (in press).
22. JOOSTEN, E.A.J., VAN DE MEENT, H., BAR, P.R., and GISPEN, W.H. (1995). Melanocortins stimulate neurite outgrowth in the injured adult rat spinal cord. J. Neurotrauma 12, 373 (abst).
23. JOOSTEN, E.A.J., VERHAAGH, S., MARTIN, D., et al. (1996). Alpha-MSH stimulates neurite outgrowth of neonatal rat corticospinal neurons in vitro. Brain Res. 736, 91-98.
24. KIMBERLIN, D.W., VALASCO, S., PARIS, M.M., HICKEY, S.M., MCCRACKEN JR, G.H., and NISEN, P.D. (1995). Modulation of expression of genes involved in the inflammatory response by lipopolysaccharide and temperature in cultured human astroglial cells. Immunol. Invest. 24, 775-785.
25. LANKHORST, A.J., VERZYL, M.R., and HAMERS, F.P.T. (in press). Experimental spinal cord contusion injury: comparison of different outcome parameters. Neurosci. Res. Comm.
26. LO, D.C. (1995). Neurotrophic factors and synaptic plasticity. Neuron 15, 979-981.
27. MCALLISTER, A.K., KATZ, L.C., and LO, D.C. (1996). Neurotrophin regulation of cortical dendritic growth requires activity. Neuron 17, 1057-1064.
28. MCALLISTER, A.K., LO, D.C., and KATZ, L.C. (1995). Neurotrophins regulate dendritic growth in developing visual cortex. Neuron 15, 791-803.
29. MEDA, L., CASSATELLA, M.A., SZENDREI, G.I., et al. (1998). Activation of microglial cells by beta-amyloid protein and interferon-gamma. Nature 374, 647-650.
30. RAJORA, N., BOCCOLI, G., BURNS, D., SHARMA, S., CATANIA, A.P., and LIPTON, J.M. (1997). Alpha-MSH modulates local and circulating tumor necrosis factor-alpha in experimental brain inflammation. J. Neurosci. 17, 2181-2186.
31. SHUMAN, S.L., BRESNAHAN, J.C., and BEATTIE, M.S. (1997). Apoptosis of microglia and oligodendrocytes after spinal cord contusion in rats. J. Neurosci. Res. 50, 798-808.
32. STRAND, F.L., and KUNG, T.T. (1980). ACTH accelerates recovery of neuromuscular function following crushing of peripheral nerve. Peptides 1, 135-138.
33. TARLOV, I.M., and KLINGER, H. (1954). Spinal cord compression studies. II. Time limits for recovery after acute compression in dogs. Arch. Neurol. Psychiatr. 71, 271-290.
34. VAN DE MEENT, H., HAMERS, F.P.T., LANKHORST, A.J., BUISE, M.P., JOOSTEN, E.A.J., and GISPEN, W.H. (1996). New assessment techniques for evaluation of posttraumatic spinal cord function in rat. J. Neurotrauma 13, 741-754.
35. VAN DE MEENT, H., HAMERS, F.P.T., LANKHORST, A.J., JOOSTEN, E.A.J., and GISPEN, W.H. (1997). Beneficial effects of the melanocortin α-melanocyte-stimulating hormone on clinical and neurophysiological recovery after experimental spinal cord injury. Neurosurgery 40, 122-131.
36. VAN DER NEUT, R., HOL, E., GISPEN, W.H., and BAR, P.R. (1992). Stimulation by melanocortins of neurite outgrowth from spinal and sensory neurons in vitro. Peptides 13, 1109-1115.
37. VAN DER ZEE, C.E.E.M., BRAKKEE, J.H., and GISPEN, W.H. (1988). αMSH and ORG.2766 in peripheral nerve regeneration: different routes of delivery. Eur. J. Pharmacol. 147, 351-357.
38. VERHAAGEN, J., EDWARDS, P.M., JENNEKENS, F.G., SCHOTMAN, P., and GISPEN, W.H. (1986). Alpha-melanocyte-stimulating hormone stimulates the outgrowth of myelinated nerve fibers after peripheral nerve crush. Exp. Neurol. 92, 451-454.
39. WILSON, J.F., ANDERSON, S., SNOOK, G., and LLEWELLYN, K.D. (1984). Quantification of the permeability of the blood-CSF barrier to α-MSH in the rat. Peptides 5, 681-685.
40. ZAJICEK, J.P., WING, M., SCOLDING, N.J., and COMPSTON, D.A.S. (1992). Interactions between oligodendrocytes and microglia. Brain 115, 1611-1631.
41. ZOHAR, M., and SALOMON, Y. (1993). Mechanisms of action of melanocortin peptides: possible role in astrocyte regulation. J. Mol. Neurosci. 4, 55-62.