-
1
-
-
0036490145
-
It's ALL in the diagnosis
-
Staudt, L.M. (2002) It's ALL in the diagnosis. Cancer Cell 1,109-110
-
(2002)
Cancer Cell
, vol.1
, pp. 109-110
-
-
Staudt, L.M.1
-
2
-
-
0033788513
-
Clinical implications of recurring chromosomal and associated molecular abnormalities in acute lymphoblastic leukemia
-
Ferrando, A.A. and Look, A.T. (2000) Clinical implications of recurring chromosomal and associated molecular abnormalities in acute lymphoblastic leukemia. Semin. Hematol. 37, 381-395
-
(2000)
Semin. Hematol.
, vol.37
, pp. 381-395
-
-
Ferrando, A.A.1
Look, A.T.2
-
3
-
-
17144474314
-
Gene expression signatures define novel oncogenic pathways in T cell acute lymphoblastic leukemia
-
Ferrando, A.A. et al. (2002) Gene expression signatures define novel oncogenic pathways in T cell acute lymphoblastic leukemia. Cancer Cell 1, 75-87
-
(2002)
Cancer Cell
, vol.1
, pp. 75-87
-
-
Ferrando, A.A.1
-
4
-
-
0037133497
-
Combined expression of pTα and Notch3 in T cell leukemia identifies the requirement of preTCR for leukemo-genesis
-
Bellavia, D. et al. (2002) Combined expression of pTα and Notch3 in T cell leukemia identifies the requirement of preTCR for leukemo-genesis. Proc. Natl Acad. Sci. USA 99, 3788-3793
-
(2002)
Proc. Natl Acad. Sci. USA
, vol.99
, pp. 3788-3793
-
-
Bellavia, D.1
-
5
-
-
0034010024
-
De novo mutation in the Notch3 gene causing CADASIL
-
Joutel, A. et al. (2000) De novo mutation in the Notch3 gene causing CADASIL. Ann. Neurol. 47, 388-391
-
(2000)
Ann. Neurol.
, vol.47
, pp. 388-391
-
-
Joutel, A.1
-
6
-
-
0034253589
-
Fringe differentially modulates Jagged1 and Delta1 signaling through Notch1 and Notch2
-
Hicks, C. et al. (2000) Fringe differentially modulates Jagged1 and Delta1 signaling through Notch1 and Notch2. Nat. Cell Biol. 2, 515-520
-
(2000)
Nat. Cell Biol.
, vol.2
, pp. 515-520
-
-
Hicks, C.1
-
7
-
-
0033617522
-
Notch signaling: Cell fate control and signal integration in development
-
Artavanis-Tsakonas, S. et al. (1999) Notch signaling: cell fate control and signal integration in development. Science 284, 770-776
-
(1999)
Science
, vol.284
, pp. 770-776
-
-
Artavanis-Tsakonas, S.1
-
8
-
-
0034671686
-
Notch signalling: From outside in
-
Mumm, S.J. and Kopan, R. (2000) Notch signalling: from outside in. Dev. Biol. 228, 151-165
-
(2000)
Dev. Biol.
, vol.228
, pp. 151-165
-
-
Mumm, S.J.1
Kopan, R.2
-
9
-
-
0034633964
-
Notch signaling: A dance of proteins changing partners
-
Kadesh, T. (2000) Notch signaling: a dance of proteins changing partners. Exp. Cell Res. 260, 1-8
-
(2000)
Exp. Cell Res.
, vol.260
, pp. 1-8
-
-
Kadesh, T.1
-
10
-
-
0034968027
-
The origin of the ankyrin repeat region in Notch intracellular domains is critical for regulation of HES promoter activity
-
Beatus, P. et al. (2001) The origin of the ankyrin repeat region in Notch intracellular domains is critical for regulation of HES promoter activity. Mech. Dev. 104, 3-20
-
(2001)
Mech. Dev.
, vol.104
, pp. 3-20
-
-
Beatus, P.1
-
11
-
-
0036606776
-
Mastermind mediates chromatin-specific transcription and turnover of the Notch enhancer complex
-
Fryer, C.J. et al. (2002) Mastermind mediates chromatin-specific transcription and turnover of the Notch enhancer complex. Genes Dev. 16, 1397-1411
-
(2002)
Genes Dev.
, vol.16
, pp. 1397-1411
-
-
Fryer, C.J.1
-
12
-
-
0036096912
-
Characterization of a high-molecular-weight Notch complex in the nucleus of Notch(ic)-transformed RKE cells and in a human T-cell leukemia cell line
-
Jeffries, S. et al. (2002) Characterization of a high-molecular-weight Notch complex in the nucleus of Notch(ic)-transformed RKE cells and in a human T-cell leukemia cell line. Mol. Cell. Biol. 22, 3927-3941
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 3927-3941
-
-
Jeffries, S.1
-
13
-
-
0033681301
-
Notch1 signaling promotes the maturation of CD4 and CD8 SP thymocytes
-
Deftos, M.L. et al. (2000) Notch1 signaling promotes the maturation of CD4 and CD8 SP thymocytes. Immunity 13, 73-84
-
(2000)
Immunity
, vol.13
, pp. 73-84
-
-
Deftos, M.L.1
-
14
-
-
0034600850
-
Constitutive activation of NF-κB and T-cell leukemia/lymphoma in Notch3 transgenic mice
-
Bellavia, D. et al. (2000) Constitutive activation of NF-κB and T-cell leukemia/lymphoma in Notch3 transgenic mice. EMBO J. 19, 3337-3348
-
(2000)
EMBO J.
, vol.19
, pp. 3337-3348
-
-
Bellavia, D.1
-
15
-
-
0036533568
-
Transgenic expression of numb inhibits notch signaling in immature thymocytes but does not alter T cell fate specification
-
French, M.B. et al. (2002) Transgenic expression of numb inhibits notch signaling in immature thymocytes but does not alter T cell fate specification. J. Immunol. 168, 3173-3180
-
(2002)
J. Immunol.
, vol.168
, pp. 3173-3180
-
-
French, M.B.1
-
16
-
-
0032055258
-
A role for Abl in Notch signaling
-
Giniger, E. (1998) A role for Abl in Notch signaling. Neuron 20, 667-681
-
(1998)
Neuron
, vol.20
, pp. 667-681
-
-
Giniger, E.1
-
17
-
-
0034024625
-
Neoplastic transformation by Notch requires nuclear localization
-
Jeffries, S. and Capobianco, A.J. (2000) Neoplastic transformation by Notch requires nuclear localization. Mol. Cell. Biol. 20, 3928-3941
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 3928-3941
-
-
Jeffries, S.1
Capobianco, A.J.2
-
18
-
-
0034719383
-
Neoplastic transformation by Notch is independent of transcriptional activation by RBP-J signalling
-
Dumont, E. et al. (2000) Neoplastic transformation by Notch is independent of transcriptional activation by RBP-J signalling. Oncogene 19, 556-561
-
(2000)
Oncogene
, vol.19
, pp. 556-561
-
-
Dumont, E.1
-
19
-
-
0033796150
-
Essential roles for ankyrin repeat and transactivation domains in induction of T-cell leukemia by Notch1
-
Aster, J.C. et al. (2000) Essential roles for ankyrin repeat and transactivation domains in induction of T-cell leukemia by Notch1. Mol. Cell. Biol. 20, 7505-7515
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 7505-7515
-
-
Aster, J.C.1
-
20
-
-
0037103148
-
A reassessment of the effect of activated Notch1 on CD4 and CD8 T cell development
-
Fowlkes, B.J. and Robey, E.A. (2002) A reassessment of the effect of activated Notch1 on CD4 and CD8 T cell development. J. Immunol. 169, 1817-1821
-
(2002)
J. Immunol.
, vol.169
, pp. 1817-1821
-
-
Fowlkes, B.J.1
Robey, E.A.2
-
21
-
-
0032783561
-
Murine leukemia provirus-mediated activation of the Notch1 gene leads to induction of HES-1 in a mouse T lymphoma cell line, DL-3
-
Lee, J.S. et al. (1999) Murine leukemia provirus-mediated activation of the Notch1 gene leads to induction of HES-1 in a mouse T lymphoma cell line, DL-3. FEBS Lett. 455, 276-280
-
(1999)
FEBS Lett.
, vol.455
, pp. 276-280
-
-
Lee, J.S.1
-
22
-
-
0037198653
-
Overexpression of the Notch target genes Hes in vivo induces lymphoid and myeloid alterations
-
Kawamata, S. et al. (2002) Overexpression of the Notch target genes Hes in vivo induces lymphoid and myeloid alterations. Oncogene 21, 3855-3863
-
(2002)
Oncogene
, vol.21
, pp. 3855-3863
-
-
Kawamata, S.1
-
23
-
-
18344388633
-
Deltex1 redirects lymphoid progenitors to the B cell lineage by antagonizing Notch1
-
Izon, D.J. et al. (2002) Deltex1 redirects lymphoid progenitors to the B cell lineage by antagonizing Notch1. Immunity 16, 231-243
-
(2002)
Immunity
, vol.16
, pp. 231-243
-
-
Izon, D.J.1
-
24
-
-
0033135269
-
The bHLH gene Hes1 is essential for expansion of early T cell precursors
-
Tomita, K. et al. (1999) The bHLH gene Hes1 is essential for expansion of early T cell precursors. Genes Dev. 13, 1203-1210
-
(1999)
Genes Dev.
, vol.13
, pp. 1203-1210
-
-
Tomita, K.1
-
25
-
-
0035286604
-
Notchless T cell maturation?
-
Rothenberg, E.V. (2001) Notchless T cell maturation? Nat. Immunol. 2, 189-190
-
(2001)
Nat. Immunol.
, vol.2
, pp. 189-190
-
-
Rothenberg, E.V.1
-
26
-
-
0032798711
-
Expression pattern of Notch1, 2 and 3 and Jagged1 and 2 in lymphoid and stromal thymus components: Distinct ligand-receptor interactions in intrathymic T cell development
-
Felli, M.P. et al. (1999) Expression pattern of Notch1, 2 and 3 and Jagged1 and 2 in lymphoid and stromal thymus components: distinct ligand-receptor interactions in intrathymic T cell development. Int. Immunol. 11, 1017-1025
-
(1999)
Int. Immunol.
, vol.11
, pp. 1017-1025
-
-
Felli, M.P.1
-
27
-
-
0033136717
-
Deficient T cell fate specification in mice with an induced inactivation of Notch1
-
Radtke, F. et al. (1999) Deficient T cell fate specification in mice with an induced inactivation of Notch1. Immunity 10, 547-558
-
(1999)
Immunity
, vol.10
, pp. 547-558
-
-
Radtke, F.1
-
28
-
-
0035796488
-
Separation of Notch1 promoted lineage commitment and expansion/transformation in developing T cells
-
Allman, D. et al. (2001) Separation of Notch1 promoted lineage commitment and expansion/transformation in developing T cells. J. Exp. Med. 194, 99-106
-
(2001)
J. Exp. Med.
, vol.194
, pp. 99-106
-
-
Allman, D.1
-
29
-
-
0036070308
-
Inactivation of Notch1 impairs VDJβ rearrangement and allows pre-TCR-independent survival of early αβ lineage thymocytes
-
Wolfer, A. et al. (2002) Inactivation of Notch1 impairs VDJβ rearrangement and allows pre-TCR-independent survival of early αβ lineage thymocytes. Immunity 16, 869-879
-
(2002)
Immunity
, vol.16
, pp. 869-879
-
-
Wolfer, A.1
-
30
-
-
0025856717
-
TAN-1, the human homolog of the Drosophila Notch gene, is broken by chromosomal translocations in T lympho-blastic neoplasm
-
Ellisen, L-V. et al. (1991) TAN-1, the human homolog of the Drosophila Notch gene, is broken by chromosomal translocations in T lympho-blastic neoplasm. Cell 66, 649-661
-
(1991)
Cell
, vol.66
, pp. 649-661
-
-
Ellisen, L.-V.1
-
31
-
-
0029942842
-
Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles
-
Pear, W.S. et al. (1996) Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles. J. Exp. Med. 183, 2283-2291
-
(1996)
J. Exp. Med.
, vol.183
, pp. 2283-2291
-
-
Pear, W.S.1
-
32
-
-
0029819876
-
Transduction of Notch2 in feline leukemia virus-induced thymic lymphoma
-
Rohn, J.L. et al. (1996) Transduction of Notch2 in feline leukemia virus-induced thymic lymphoma. J. Virol. 70, 8071-8080
-
(1996)
J. Virol.
, vol.70
, pp. 8071-8080
-
-
Rohn, J.L.1
-
33
-
-
0036467663
-
Direct induction of T lymphocyte-specific gene expression by the mammalian Notch signaling pathway
-
Reizis, B. and Leder, P. (2002) Direct induction of T lymphocyte-specific gene expression by the mammalian Notch signaling pathway. Genes Dev. 16, 295-300
-
(2002)
Genes Dev.
, vol.16
, pp. 295-300
-
-
Reizis, B.1
Leder, P.2
-
34
-
-
0033637216
-
NF-κB activation by pre-T Cell receptor serves as a selective survival signal in T lymphocyte development
-
Voll, R.E. et al. (2000) NF-κB activation by pre-T Cell receptor serves as a selective survival signal in T lymphocyte development. Immunity 13, 677-689
-
(2000)
Immunity
, vol.13
, pp. 677-689
-
-
Voll, R.E.1
-
35
-
-
0035350807
-
2+ mobilization and activation of NF-κB and NFAT
-
2+ mobilization and activation of NF-κB and NFAT. Nat. Immun. 2, 403-409
-
(2001)
Nat. Immun.
, vol.2
, pp. 403-409
-
-
Aifantis, I.1
-
37
-
-
0031594575
-
NFκB2 is a putative target gene of activated Notch1 via RBP-Jκ
-
Oswald, F. et al. (1998) NFκB2 is a putative target gene of activated Notch1 via RBP-Jκ. Mol. Cell. Biol. 18, 2077-2088
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 2077-2088
-
-
Oswald, F.1
-
38
-
-
0029980867
-
T cell leukemia-associated human Notch/Translocation-associated Notch homologue has IκB-like activity and physically interacts with nuclear factor-κB proteins in T cells
-
Guan, E. et al. (1996) T cell leukemia-associated human Notch/Translocation-associated Notch homologue has IκB-like activity and physically interacts with nuclear factor-κB proteins in T cells. J. Exp. Med. 183, 2025-2032
-
(1996)
J. Exp. Med.
, vol.183
, pp. 2025-2032
-
-
Guan, E.1
-
39
-
-
0035399803
-
Human Notch1 inhibits NF-κB activity in the nucleus through a direct interaction involving a novel domain
-
Wang, J. et al. (2001) Human Notch1 inhibits NF-κB activity in the nucleus through a direct interaction involving a novel domain. J. Immunol. 167, 289-295
-
(2001)
J. Immunol.
, vol.167
, pp. 289-295
-
-
Wang, J.1
-
40
-
-
0031923281
-
Notch inhibition of E47 supports the existence of a novel signaling pathway
-
Ordentlich, P. et al. (1998) Notch inhibition of E47 supports the existence of a novel signaling pathway. Mol. Cell. Biol. 18, 2230-2239
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 2230-2239
-
-
Ordentlich, P.1
-
41
-
-
0036217915
-
E protein function in lymphocyte development
-
Quong, M.W. et al. (2002) E protein function in lymphocyte development. Annu. Rev. Immunol. 20, 301-322
-
(2002)
Annu. Rev. Immunol.
, vol.20
, pp. 301-322
-
-
Quong, M.W.1
-
42
-
-
0035881544
-
E2A and HEB activate the pre-TCRα promoter during immature T cell development
-
Takeuchi, A. et al. (2001) E2A and HEB activate the pre-TCRα promoter during immature T cell development. J. Immunol. 167, 2157-2163
-
(2001)
J. Immunol.
, vol.167
, pp. 2157-2163
-
-
Takeuchi, A.1
-
43
-
-
0037143763
-
Disruption of pre-TRC expression accelerates lymphomagenesis in E2A-deficient mice
-
Engel, I. and Murre, C. (2002) Disruption of pre-TRC expression accelerates lymphomagenesis in E2A-deficient mice. Proc. Natl Acad. Sci. U.S.A. 99, 11322-11327
-
(2002)
Proc. Natl Acad. Sci. U.S.A.
, vol.99
, pp. 11322-11327
-
-
Engel, I.1
Murre, C.2
-
44
-
-
0034252945
-
SCL and LMO1 alter thymocyte differentiation: Inhibition of E2A-HEB function and pre-Tα chain expression
-
Herblot, S. et al. (2000) SCL and LMO1 alter thymocyte differentiation:inhibition of E2A-HEB function and pre-Tα chain expression. Nat. Immun. 1, 138-143
-
(2000)
Nat. Immun.
, vol.1
, pp. 138-143
-
-
Herblot, S.1
-
45
-
-
0035005101
-
New protease inhibitors prevent γ-secretase-mediated production of Aβ40/42 without affecting Notch cleavage
-
Petit, A. et al. (2001) New protease inhibitors prevent γ-secretase-mediated production of Aβ40/42 without affecting Notch cleavage. Nat. Cell Biol. 3, 507-511
-
(2001)
Nat. Cell Biol.
, vol.3
, pp. 507-511
-
-
Petit, A.1
-
46
-
-
0035476891
-
Differential effects of Notch ligands Delta-1 and Jagged-1 in human lymphoid differentiation
-
Jaleco, A.C. et al. (2001) Differential effects of Notch ligands Delta-1 and Jagged-1 in human lymphoid differentiation. J. Exp. Med. 194, 991-1001
-
(2001)
J. Exp. Med.
, vol.194
, pp. 991-1001
-
-
Jaleco, A.C.1
-
47
-
-
0035895087
-
A novel Notch ligand, Dll4, induces T cell leukemia/lymphoma when overexpressed in mice by retroviral-mediated gene transfer
-
Yan, X.-Q. et al. (2001) A novel Notch ligand, Dll4, induces T cell leukemia/lymphoma when overexpressed in mice by retroviral-mediated gene transfer. Blood 98, 3793-3799
-
(2001)
Blood
, vol.98
, pp. 3793-3799
-
-
Yan, X.-Q.1
|