Constitutive pre-TCR signaling promotes differentiation through Ca2+ mobilization and activation of NF-κB and NFAT

Nature Immunology

Volumn 2, Issue 5, 2001, Pages 403-409

  Aifantis, Iannis ^a   Gounari, Fotini ^a   Scorrano, Luca ^a   Borowski, Christine ^a   Von Boehmer, Harald ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA BINDING PROTEIN; GEM PROTEIN, HUMAN; GEM PROTEIN, MOUSE; IMMEDIATE EARLY PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LYMPHOCYTE ANTIGEN RECEPTOR; MEMBRANE PROTEIN; MONOMERIC GUANINE NUCLEOTIDE BINDING PROTEIN; NUCLEAR PROTEIN; PRE T CELL RECEPTOR ALPHA; PRE-T CELL RECEPTOR ALPHA; RAG2 PROTEIN, MOUSE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR NFAT; V(D)J RECOMBINATION ACTIVATING PROTEIN 2;

ANIMAL; ARTICLE; BAGG ALBINO MOUSE; BIOLOGICAL MODEL; CALCIUM SIGNALING; CELL DIFFERENTIATION; CYTOLOGY; GENETIC SELECTION; HEMATOPOIETIC STEM CELL; IMMUNOLOGY; METABOLISM; MOUSE; MOUSE MUTANT; SIGNAL TRANSDUCTION; T LYMPHOCYTE; THYMUS;

ANIMALS; CALCIUM SIGNALING; CELL DIFFERENTIATION; DNA-BINDING PROTEINS; HEMATOPOIETIC STEM CELLS; IMMEDIATE-EARLY PROTEINS; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED BALB C; MICE, MUTANT STRAINS; MODELS, GENETIC; MONOMERIC GTP-BINDING PROTEINS; NF-KAPPA B; NFATC TRANSCRIPTION FACTORS; NUCLEAR PROTEINS; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; SELECTION (GENETICS); SIGNAL TRANSDUCTION; T-LYMPHOCYTES; THYMUS GLAND; TRANSCRIPTION FACTORS;

EID: 0035350807     PISSN: 15292908     EISSN: None     Source Type: Journal    
DOI: 10.1038/87704     Document Type: Article

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