Negative regulation of mitotic promoting factor by the checkpoint kinase Chk1 in simian virus 40 lytic infection

Journal of Virology

Volumn 77, Issue 2, 2003, Pages 1257-1267

  Okubo, Eiji ^b   Lehman, John M ^a   Friedrich, Thomas D ^a  

^a ALBANY MEDICAL COLLEGE   (United States)

^b NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHECKPOINT KINASE 1; PROTEIN KINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CELL CYCLE S PHASE; CERCOPITHECIDAE; CONTROLLED STUDY; DNA CONTENT; DNA DAMAGE; DNA REPLICATION; ENZYME ACTIVITY; ENZYME INHIBITION; KIDNEY CELL; MITOSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONTENT; PROTEIN DEPHOSPHORYLATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; SIMIAN VIRUS 40; VIRUS INFECTION; VIRUS MUTANT;

ALKALOIDS; ANIMALS; CAFFEINE; CELL LINE; CERCOPITHECUS AETHIOPS; ENZYME ACTIVATION; ENZYME INHIBITORS; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; MITOSIS; NOCODAZOLE; PHOSPHORYLATION; PROTEIN KINASE INHIBITORS; PROTEIN KINASES; SIMIAN VIRUS 40; STAUROSPORINE; VIRAL PROTEINS;

EID: 0037223773     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.77.2.1257-1267.2003     Document Type: Article

References (78)

1. 2/M checkpoint arrest in cells exposed to ionizing radiation. J. Biol. Chem. 274:2732-2742.
2. Abraham, R. T. 2001. Cell cycle checkpoint signaling through the ATM and ATR kinases. Genes Dev. 15:2177-2196.
3. Blasina, A., I. V. de Weyer, M. C. Laus, W. H. Luyten, A. E. Parker, and C. H. McGowan. 1999. A human homologue of the checkpoint kinase Cds1 directly inhibits Cdc25 phosphatase. Curr. Biol. 9:1-10.
4. 2/M checkpoint after ultraviolet radiation requires p38 kinase. Nature 411:102-107.
5. Busby, E. C., D. F. Leistritz, R. T. Abraham, L. M. Karnitz, and J. N. Sarkaria. 2000. The radiosensitizing agent 7-hydroxystaurosporine (UCN-01) inhibits the DNA damage checkpoint kinase hChk1. Cancer Res. 60:2108-2112.
6. Chang, T. H., F. A. Ray, D. A. Thompson, and R. Schlegel. 1997. Disregulation of mitotic checkpoints and regulatory proteins following acute expression of SV40 large T antigen in diploid human cells. Oncogene 14:2383-2393.
7. Chaturvedi, P., W. K. Eng, Y. Zhu, M. R. Mattern, R. Mishra, M. R. Hurle, X. Zhang, R. S. Annan, Q. Lu, L. F. Faucette, G. F. Scott, X. Li, S. A. Carr, R. K. Johnson, J. D. Winkler, and B. B. Zhou. 1999. Mammalian Chk2 is a downstream effector of the ATM-dependent DNA damage checkpoint pathway. Oncogene 18:4047-4054.
8. Cicala, C., M. L. Avantaggiati, A. Graessmann, K. Rundell, A. S. Levine, and M. Carbone. 1994. Simian virus 40 small-t antigen stimulates viral DNA replication in permissive monkey cells. J. Virol. 68:3138-3144.
9. Digweed, M., I. Demuth, S. Rothe, R. Scholz, A. Jordan, C. Grotzinger, D. Schindler, M. Grompe, and K. Sperling. 2002. SV40 large T-antigen disturbs the formation of nuclear DNA-repair foci containing MRE11. Oncogene 21:4873-4878.
10. Feijoo, C., C. Hall-Jackson, R. Wu, D. Jenkins, J. Leitch, D. M. Gilbert, and C. Smythe. 2001. Activation of mammalian Chk1 during DNA replication arrest: A role for Chk1 in the intra-S phase checkpoint monitoring replication origin firing. J. Cell Biol. 154:913-923.
11. Friedrich, T. D., J. Laffin, and J. M. Lehman. 1992. Simian virus 40 large T-antigen function is required for induction of tetraploid DNA content during lyric infection. J. Virol. 66:4576-4579.
12. 2 phase of the cell cycle. J. Virol. 68:4028-4030.
13. 2-phase DNA content. Cytometry 31:260-264.
14. Furnari, B., N. Rhind, and P. Russell, 1997. Cdc25 mitotic inducer targeted by chk1 DNA damage checkpoint kinase. Science 277:1495-1497.
15. Gaillard, S., K. M. Fahrbach, R. Parkati, and K. Rundell. 2001. Overexpression of simian virus 40 small-t antigen blocks centrosome function and mitotic progression in human fibroblasts. J. Virol. 75:9799-9807.
16. Gauchat, J. F., and R. Weil. 1986. On the functional roles of simian virus 40 large and small T-antigen in the induction of a mitotic host response. Nucleic Acids Res. 14:9339-9351.
17. Gershey, E. L. 1979. Simian virus 40-host cell interaction during lytic infection. J. Virol. 30:76-83.
18. Gjoerup, O., H. Chao, J. A. DeCaprio, and T. M. Roberts. 2000. pRB-dependent, J domain-independent function of simian virus 40 large T antigen in override of p53 growth suppression. J. Virol. 74:864-874.
19. Golsteyn, R. M., K. E. Mundt, A. M. Fry, and E. A. Nigg. 1995. Cell cycle regulation of the activity and subcellular localization of PLK1, a human protein kinase implicated in mitotic spindle function. J. Cell Biol. 129:1617-1628.
20. Graves, P. R., L. Yu, J. K. Schwarz, J. Gales, E. A. Sausville, P. M. O'Connor, and H. Piwnica-Worms. 2000. The Chk1 protein kinase and the Cdc25C regulatory pathways are targets of the anticancer agent UCN-01. J. Biol. Chem. 275:5600-5605.
21. Guo, Z., A. Kumagai, S. X. Wang, and W. G. Dunphy. 2000. Requirement for Atr in phosphorylation of Chk1 and cell cycle regulation in response to DNA replication blocks and UV-damaged DNA in Xenopus egg extracts. Genes Dev. 14:2745-2756.
22. 2 and spreads in an ordered fashion coincident with mitotic chromosome condensation. Chromosoma 106:348-360.
23. 2 cell cycle arrest: vpr interferes with cell cycle signaling cascades by interacting with the B subunit of serine/threonine protein phosphatase 2A. EMBO J. 19:3956-3967.
24. Jackson, J. R., A. Gilmartin, C. Imburgia, J. D. Winkler, L. A. Marshall, and A. Roshak. 2000. An indolocarbazole inhibitor of human checkpoint kinase (Chk1) abrogates cell cycle arrest caused by DNA damage. Cancer Res. 60:566-572.
25. Jault, F. M., J. M. Jault, F. Ruchti, E. A. Fortunato, C. Clark, J. Corbeil, D. D. Richman, and D. H. Spector. 1995. Cytomegalovirus infection induces high levels of cyclins, phosphorylated Rb, and p53, leading to cell cycle arrest. J. Virol. 69:6697-6704.
26. 2+M phase of the cell cycle. J. Virol. 69:6304-6313.
27. Karaiskou, A., C. Jessus, T. Brassac, and R. Ozon. 1999. Phosphatase 2A and polo kinase, two antagonistic regulators of cdc25 activation and MPF auto-amplification. J. Cell Sci. 112:3747-3756.
28. Karlsson, C., S. Katich, A. Hagting, I. Hoffmann, and J. Pines. 1999. Cdc25B and Cdc25C differ markedly in their properties as initiators of mitosis. J. Cell Biol. 146:573-584.
29. Laffin, J., and J. M. Lehman. 1994. Detection of intracellular virus and viral products. Methods Cell Biol. 41:543-557.
30. 2/M phase transition in human cells. J. Cell Sci. 111:2445-2453.
31. Lee, J., A. Kumagai, and W. G. Dunphy. 2001. Positive regulation of wee1 by chk1 and 14-3-3 proteins. Mol. Biol. Cell 12:551-563.
32. Lehman, J. M. 1974. Early chromosome changes in diploid Chinese hamster cells after infection with simian virus 40. Int. J. Cancer 13:164-172.
33. Lehman, J. M., J. Laffin, and T. D. Friedrich. 1994. DNA content distribution of mouse cells following infection with polyoma virus. Cytometry 16:138-143.
34. 2 and second S phase in CV-1 cells. Exp. Cell Res. 258:215-222.
35. Lehman, J. M., J. Laffin, J. W. Jacobberger, and D. Fogleman. 1988. Analysis of simian virus 40 infection of CV-1 cells by quantitative two-color fluorescence with flow cytometry. Cytometry 9:52-59.
36. 2/M DNA damage checkpoint. Genes Dev. 14:1448-1459.
37. 1 to S. J. Virol. 70:8850-8857.
38. 2 checkpoint mechanism. Neoplasia 3:411-419.
39. Michael, W. M., R. Ott, E. Fanning, and J. Newport. 2000. Activation of the DNA replication checkpoint through RNA synthesis by primase. Science 289:2133-2137.
40. 2 arrest and its abrogation by caffeine in FL-amnion cells with or without p53. Exp. Cell Res. 262:37-48.
41. Moorhead, P. S., and E. Saksela. 1965. The sequence of chromosome aberrations during SV 40 transformation of a human diploid cell strain. Hereditas 52:271-284.
42. 2 phase with accumulation of mitotic cyclins. J. Virol. 75:7555-7563.
43. Morris, M. C., A. Heitz, J. Mery, F. Heitz, and G. Divita. 2000. An essential phosphorylation-site domain of human cdc25C interacts with both 14-3-3 and cyclins. J. Biol. Chem. 275:28849-28857.
44. Muller, J., S. Ory, T. Copeland, H. Piwnica-Worms, and D. K. Morrison. 2001. C-TAK1 regulates Ras signaling by phosphorylating the MAPK scaffold, KSR1. Mol. Cell 8:983-993.
45. 2 DNA damage checkpoint inhibiting cdc2 by Y15 phosphorylation. EMBO J. 16:545-554.
46. Ogg, S., B. Gabrielli, and H. Piwnica-Worms. 1994. Purification of a serine kinase that associates with and phosphorylates human Cdc25C on serine 216. J. Biol. Chem. 269:30461-30469.
47. Ouyang, B., W. Li, H. Pan, J. Meadows, I. Hoffmann, and W. Dai. 1999. The physical association and phosphorylation of Cdc25C protein phosphatase by Prk. Oncogene 18:6029-6036.
48. Ouyang, B., H. Pan, L. Lu, J. Li, P, Stambrook, B. Li, and W. Dai. 1997. Human Prk is a conserved protein serine/threonine kinase involved in regulating M phase functions. J. Biol. Chem. 272:28646-28651.
49. Peng, C. Y., P. R. Graves, S. Ogg, R. S. Thoma, M. J. Byrnes III, Z. Wu, M. T. Stephenson, and H. Piwnica-Worms. 1998. C-TAK1 protein kinase phosphorylates human Cdc25C on serine 216 and promotes 14-3-3 protein binding. Cell Growth Differ. 9:197-208.
50. 2 checkpoint control: Regulation of 14-3-3 protein binding by phosphorylation of Cdc25C on serine-216. Science 277:1501-1505.
51. 2/M phase cell cycle arrest is associated with inhibition of p34(cdc2). J. Virol. 75:7429-7434.
52. 2/M cell cycle arrest requires σ1s and occurs in the absence of apoptosis. J. Virol. 74:9562-9570.
53. Quartin, R. S., C. N. Cole, J. M. Pipas, and A. J. Levine. 1994. The aminoterminal functions of the simian virus 40 large T antigen are required to overcome wild-type p53-mediated growth arrest of cells. J. Virol. 68:1334-1341.
54. Ray, F. A., D. S. Peabody, J. L. Cooper, L. S. Cram, and P. M. Kraemer. 1990. SV40 T antigen alone drives karyotype instability that precedes neoplastic transformation of human diploid fibroblasts. J. Cell. Biochem. 42:13-31.
55. Rothblum-Oviatt, C. J., C. E. Ryan, and H. Piwnica-Worms. 2001. 14-3-3 Binding regulates catalytic activity of human wee1 kinase. Cell Growth Differ. 12:581-589.
56. Sanchez, Y., C. Wong, R. S. Thoma, R. Richman, Z. Wu, H. Piwnica-Worms, and S. J. Elledge. 1997. Conservation of the Chk1 checkpoint pathway in mammals: Linkage of DNA damage to Cdk regulation through Cdc25. Science 277:1497-1501.
57. Sarkaria, J. N., E. C. Busby, R. S. Tibbetts, P. Roos, Y. Taya, L. M. Karnitz, and R. T. Abraham. 1999. Inhibition of ATM and ATR kinase activities by the radiosensitizing agent, caffeine. Cancer Res. 59:4375-4382.
58. Scarano, F. J., J. A. Laffin, J. M. Lehman, and T. D. Friedrich. 1994. Simian Virus 40 prevents activation of M-phase-promoting factor during lyric infection. J. Virol. 68:2355-2361.
59. Seynaeve, C. M., M. G. Kazanietz, P. M. Blumberg, E. A. Sausville, and P. J. Worland. 1994. Differential inhibition of protein kinase C isozymes by UCN-01, a staurosporine analogue. Mol. Pharmacol. 45:1207-1214.
60. Shenk, T. E., J. Carbon, and P. Berg. 1976. Construction and analysis of viable deletion mutants of simian virus 40. J. Virol. 18:664-671.
61. Shieh, S. Y., J. Ahn, K. Tamai, Y. Taya, and C. Prives. 2000. The human homologs of checkpoint kinases Chk1 and Cds1 (Chk2) phosphorylate p53 at multiple DNA damage-inducible sites. Genes Dev. 14:289-300.
62. 2/M transition. Biochim. Biophys. Acta 1519:1-12.
63. Stewart, N., and S. Bacchetti. 1991. Expression of SV40 large T antigen, but not small t antigen, is required for the induction of chromosomal aberrations in transformed human cells. Virology 180:49-57.
64. Takizawa, C. G., and D. O. Morgan. 2000. Control of mitosis by changes in the subcellular location of cyclin-B1-Cdk1 and Cdc25C. Curr. Opin. Cell Biol. 12:658-665.
65. Tegtmeyer, P. 1972. Simian virus 40 deoxyribonucleic acid synthesis: The viral replicon. J. Virol. 10:591-598.
66. Toyoshima-Morimoto, F., E. Taniguchi, and E. Nishida. 2002. Plk1 promotes nuclear translocation of human Cdc25C during prophase. EMBO Rep. 3:341-348.
67. van Vugt, M. A., V. A. Smits, R. Klompmaker, and R. H. Medema. 2001. Inhibition of Polo-like kinase-1 by DNA damage occurs in an ATM- or ATR-dependent fashion. J. Biol. Chem. 276:41656-41660.
68. Waga, S., and B. Stillman. 1998. The DNA replication fork in eukaryotic cells. Annu. Rev. Biochem. 67:721-751.
69. Wang, X., C. H. McGowan, M. Zhao, L. He, J. S. Downey, C. Fearns, Y. Wang, S. Huang, and J. Han. 2000. Involvement of the MKK6-p38γ cascade in γ-radiation-induced cell cycle arrest. Mol. Cell. Biol. 20:4543-4552.
70. 2 during lytic infection. Exp. Cell Res. 251:121-127.
71. Wolman, S. R., K. Hirschhorn, and G. J. Todaro. 1964. Chromosomal changes in SV40-infected human fibroblast cultures. Cytogenetics 3:45-61.
72. Xie, S., H. Wu, Q. Wang, J. P. Cogswell, I. Husain, C. Conn, P. Stambrook, M. Jhanwar-Uniyal, and W. Dai. 2001. Plk3 functionally links DNA damage to cell cycle arrest and apoptosis at least in part via the p53 pathway. J. Biol. Chem. 276:43305-43312.
73. Yang, S. I., R. L. Lickteig, R. Estes, K. Rundell, G. Walter, and M. C. Mumby. 1991. Control of protein phosphatase 2A by simian virus 40 small-t antigen. Mol. Cell. Biol. 11:1988-1995.
74. 2 arrest through a Cdc2-dependent pathway that is associated with inactivation of the Wee1Hu kinase and activation of the Cdc25C phosphatase. J. Biol. Chem. 273:33455-33464.
75. Zeng, Y., K. C. Forbes, Z. Wu, S. Moreno, H. Piwnica-Worms, and T. Enoch. 1998. Replication checkpoint requires phosphorylation of the phosphatase Cdc25 by Cds1 or Chk1. Nature 395:507-510.
76. Zhang, S. H., R. Kobayashi, P. R. Graves, H. Piwnica-Worms, and N. K. Tonks. 1997. Serine phosphorylation-dependent association of the band 4.1-related protein-tyrosine phosphatase PTPH1 with 14-3-3β protein. J. Biol. Chem. 272:27281-27287.
77. Zhao, H., and H. Piwnica-Worms. 2001. Atr-mediated checkpoint pathways regulate phosphorylation and activation of human chk1. Mol. Cell. Biol. 21:4129-4139.
78. Zhou, X. Y., X. Wang, B. Hu, J. Guan, G. Iliakis, and Y. Wang. 2002. An ATM-independent S-phase checkpoint response involves CHK1 pathway. Cancer Res. 62:1598-1603.