Okadaic acid induces appearance of the mitotic epitope MPM-2 in SV40- infected CV-1 cells with a >G2-phase DNA content

Cytometry

Volumn 31, Issue 4, 1998, Pages 260-264

  Friedrich, Thomas D ^a   Okubo, Eiji ^a   Laffin, Judith ^a   Lehman, John M ^a  

^a ALBANY MEDICAL COLLEGE   (United States)

Author keywords

Cell cycle; Endoreplication; Flow cytometry; MPM 2; Okadaic acid; SV40

Indexed keywords

OKADAIC ACID;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; CELL CYCLE G2 PHASE; CELL CYCLE S PHASE; DNA CONTENT; DNA SYNTHESIS; MITOSIS; NONHUMAN; PRIORITY JOURNAL; SIMIAN VIRUS 40; TETRAPLOIDY; VIRUS INFECTION;

ANIMALS; CELL LINE; CERCOPITHECUS AETHIOPS; DNA; EPITOPES; FLOW CYTOMETRY; G2 PHASE; MITOSIS; OKADAIC ACID; PHOSPHOPROTEINS; POLYPLOIDY; SIMIAN VIRUS 40;

ANIMALIA; SIMIAE; SIMIAN VIRUS; SIMIAN VIRUS 40;

EID: 0031977909     PISSN: 01964763     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0320(19980401)31:4<260::AID-CYTO5>3.0.CO;2-N     Document Type: Article

References (41)

1. Bartz SR, Rogel ME, Emerman M: Human immunodeficiency virus type 1 cell cycle control: Vpr is cytostatic and mediates G2 accumulation by a mechanism which differs from DNA damage checkpoint control. J Virol 70:2324-2331, 1996.
2. Clarke PR, Hoffmann I, Draetta G, Karsenti E: Dephosphorylation of cdc25-C by a type-2A protein phosphatase: Specific regulation during the cell cycle in Xenopus egg extracts. Mol Biol Cell 4:397-411, 1993.
3. Davis FM, Tsao TY, Fowler SK, Rao PN: Monoclonal antibodies to mitotic cells. Proc Natl Acad Sci USA 80:2926-2930, 1983.
4. Davis MA, Smith MW, Chang SH, Trump BF: Characterization of a renal epithelial cell model of apoptosis using okadaic acid and the NRK-52E cell line. Toxicol Pathol 22:595-605, 1994.
5. Downes CS, Musk SR, Watson JV, Johnson RT: Caffeine overcomes a restriction point associated with DNA replication, but does not accelerate mitosis. J Cell Biol 110:1855-1859, 1990.
6. Friedrich TD, Laffin J, Lehman JM: Hypophosphorylated retinoblastoma gene product accumulates in SV40-infected CV-1 cells acquiring a tetraploid DNA content. Oncogene 8:1673-1677, 1993.
7. Gershey EL: Simian virus 40-host cell interaction during lytic infection. J Virol 30:76-83, 1979.
8. 2-phase to induce premature mitosis in HeLa cells. Exp Cell Res 227:165-169, 1996.
9. Guo XW, Th'ng JP, Swank RA, Anderson HJ, Tudan C, Bradbury EM, Roberge M: Chromosome condensation induced by fostriecin does not require p34cdc2 kinase activity and histone H1 hyperphosphorylation, but is associated with enhanced histone H2A and H3 phosphorylation. EMBO J 14:976-985, 1995.
10. He J, Choe S, Walker R, Di Marzio P, Morgan DO, Landau NR: Human immunodeficiency virus type 1 viral protein R (Vpr) arrests cells in the G2 phase of the cell cycle by inhibiting p34cdc2 activity J Virol 69:6705-6711, 1995.
11. Hiscott JB, Defendi V: Simian virus 40 gene A regulation of cellular DNA synthesis. I. In permissive cells. J Virol 30:590-599, 1979.
12. Hoffmann I, Clarke PR, Marcote MJ, Karsenti E, Draetta G: Phosphorylation and activation of human cdc25-C by cdc2 - Cyclin B and its involvement in the self-amplification of MPF at mitosis. EMBO J 12:53-63, 1993.
13. Jacobberger JW, Fogleman D, Lehman JM: Analysis of intracellular antigens by flow cytometry. Cytometry 7:356-364, 1986.
14. Kawabe T, Muslin AJ, Korsmeyer SJ: HOX11 interacts with protein phosphatases PP2A and PP1 and disrupts a G2/M cell-cycle checkpoint. Nature 385:454-458, 1997.
15. cdc-kinase activation invertebrates. EMBO J 10:3331-3341, 1991.
16. Kuang J, Ashorn CL, Gonzalez-Kuyvenhoven M, Penkala JE: cdc25 is one of the MPM-2 antigens involved in the activation of maturation-promoting factor. Mol Biol Cell 5:135-145, 1994.
17. Laffin J, Lehman JM: Detection of intracellular virus and viral products. Methods Cell Biol 33:271-284, 1990.
18. Lazebnik YA, Cole S, Cooke CA, Nelson WG, Earnshaw WC: Nuclear events of apoptosis in vitro in cell-free mitotic extracts: A model system for analysis of the active phase of apoptosis. J Cell Biol 123:7-22, 1993.
19. Lehman JM, Friedrich TD, Laffin J: Quantitation of simian virus 40 T-antigen correlated with the cell cycle of permissive and non-permissive cells. Cytometry 14:401-410, 1993.
20. Lehman JM, Laffin J, Jacobberger JW, Fogleman D: Analysis of simian virus 40 infection of CV-1 cells by quantitative two-color fluorescence with flow cytometry. Cytometry 9:52-59, 1988.
21. Matsumoto-Taniura N, Pirollet F, Monroe R, Gerace L, Westendorf JM: Identification of novel M phase phosphoproteins by expression cloning. Mol Biol Cell 7:1455-1469, 1996.
22. Mueller PR, Coleman TR, Dunphy WG: Cell cycle regulation of a Xenopus Wee1-like kinase. Mol Biol Cell 6:119-134, 1995.
23. Mueller PR, Coleman TR, Kumagai A, Dunphy WG: Myt1: A membrane-associated inhibitory kinase that phosphorylates Cdc2 on both threonine-14 and tyrosine-15. Science 270:86-90, 1995.
24. Nigg EA: Cyclin-dependent protein kinases: Key regulators of the eukaryotic cell cycle [review]. Bioessays 17:471-480, 1995.
25. cdc2 protein kinase in vertebrates. EMBO J 10:3321-3329, 1991.
26. Paulson JR, Patzlaff JS, Vallis AJ: Evidence that the endogenous histone H1 phosphatase in HeLa mitotic chromosomes is protein phosphatase 1, not protein phosphatase 2A.J Cell Sci 109:1437-1447, 1996.
27. Re F, Braaten D, Franke EK, Luban J: Human immunodeficiency virus type 1 Vpr arrests the cell cycle in G2 by inhibiting the activation of p34cdc2-cyclin B. J Virol 69:6859-6864, 1995.
28. Scarano FJ, Laffin JA, Lehman JM, Friedrich TD: Simian Virus 40 prevents activation of M-phase-promoting factor during lytic infection. J Virol 68:2355-2361, 1994.
29. Schlegel R, Belinsky GS, Harris MO: Premature mitosis induced in mammalian cells by the protein kinase inhibitors 2-aminopurine and 6-dimethylaminopurine. Cell Growth Diff 1:171-178, 1990.
30. Steinmann KE, Belinsky GS, Lee D, Schlegel R: Chemically induced premature mitosis: Differential response in rodent and human cells and the relationship to cyclin B synthesis and p34cdc2/cyclin B complex formation. Proc Natl Acad Sci USA 88:6843-6847, 1991.
31. Taagepera S, Dent P, Her JH, Sturgill TW, Gorbsky GJ: The MPM-2 antibody inhibits mitogen-activated protein kinase activity by binding to an epitope containing phosphothreonine-183-Mol Biol Cell 5:1243-1251, 1994.
32. Taagepera S, Rao PN, Drake FH, Gorbsky GJ: DNA topoisomerase II alpha is the major chromosome protein recognized by the mitotic phosphoprotein antibody MPM-2. Proc Natl Acad Sci USA 90:8407-8411, 1993.
33. Takai A, Murata M, Torigoe K, Isohe M, Mieskes G, Yasumoto T: Inhibitory effect of okadaic acid derivatives on protein phosphatases. A study on structure-affinity relationship. Biochem J 284:539-544, 1992.
34. Tam SW, Belinsky GS, Schlegel R: Premature expression of cyclin B sensitizes human HT1080 cells to caffeine-induced premature mitosis. J Cell Biochem 59:339-349, 1995.
35. Th'ng JP, Wright PS, Hamaguchi J, Lee MG, Norbury CJ, Nurse P, Bradbury EM: The FT210 cell line is a mouse G2 phase mutant with a temperature-sensitive CDC2 gene product. Cell 63:313-324, 1990.
36. Vandre DD, Centonze VE, Peloquin J, Tombes RM, Borisy GG: Proteins of the mammalian mitotic spindle: Phosphorylation/ dephosphorylation of MAP-4 during mitosis. J Cell Sci 98:577-588, 1991.
37. Vandre DD, Davis FM, Rao PN, Borisy GG: Distribution of cytoskeletal proteins sharing a conserved phosphorylated epitope. Eur J Cell Biol 41:72-81, 1986.
38. Westendorf JM, Rao PN, Gerace L: Cloning of cDNAs for M-phase phosphoproteins recognized by the MPM2 monoclonal antibody and determination of the phosphorylated epitope. Proc Natl Acad Sci USA 91:714-718, 1994.
39. Yamashita K, Yasuda H, Pines J, Yasumoto K, Nishitani H, Ohtsubo M, Hunter T, Sugimura T, Nishimoto T: Okadaic acid, a potent inhibitor of type 1 and type 2A protein phosphatases, activates cdc2/H1 kinase and transiently induces a premature mitosis-like state in BHK21 cells. EMBO J 9:4331-4338, 1990.
40. Yoshida M, Usui T, Tsujimura K, Inagaki M, Beppu T, Horinouchi S: Biochemical differences between staurosporine-induced apoptosis and premature mitosis. Exp Cell Res 232:225-239, 1997.
41. Zhao Y, Cao J, O'Gorman MR, Yu M, Yogev R: Effect of human immunodeficiency virus type 1 protein R (vpr) gene expression on basic cellular function of fission yeast Schizosaccharomyces pombe. J Virol 70:5821-5826, 1996.