-
1
-
-
0025004442
-
Deoxyribonucleotide analogs as inhibitors and substrates of DNA polymerases
-
Wright GE, Brown NC: Deoxyribonucleotide analogs as inhibitors and substrates of DNA polymerases. Pharmacol Ther 47:447-497, 1990
-
(1990)
Pharmacol Ther
, vol.47
, pp. 447-497
-
-
Wright, G.E.1
Brown, N.C.2
-
2
-
-
0028990381
-
Mitochondrial toxicity of antiviral drugs
-
Lewis W, Dalakas MC: Mitochondrial toxicity of antiviral drugs. Nat Med 1:417-422, 1995
-
(1995)
Nat Med
, vol.1
, pp. 417-422
-
-
Lewis, W.1
Dalakas, M.C.2
-
3
-
-
0028783393
-
Mitochondrial toxicity - New adverse drug effects
-
Swartz MN: Mitochondrial toxicity - new adverse drug effects [editorial;comment]. N Engl J Med 333:1099-1105, 1995
-
(1995)
N Engl J Med
, vol.333
, pp. 1099-1105
-
-
Swartz, M.N.1
-
4
-
-
0033604038
-
Mitochondrial toxicity induced by nucleoside-analogue reverse-transcriptase inhibitors is a key factor in the pathogenesis of antiretroviral-therapy-related lipodystrophy
-
Brinkman K, Smeitink JA, Romijn JA, et al: Mitochondrial toxicity induced by nucleoside-analogue reverse-transcriptase inhibitors is a key factor in the pathogenesis of antiretroviral-therapy-related lipodystrophy [comment]. Lancet 354:1112-1115, 1999
-
(1999)
Lancet
, vol.354
, pp. 1112-1115
-
-
Brinkman, K.1
Smeitink, J.A.2
Romijn, J.A.3
-
5
-
-
0033935975
-
Pharmacology of nucleoside and nucleotide reverse transcriptase inhibitor-induced mitochondrial toxicity
-
Kakuda TN: Pharmacology of nucleoside and nucleotide reverse transcriptase inhibitor-induced mitochondrial toxicity [in process citationl. Clin Ther 22:685-708, 2000
-
(2000)
Clin Ther
, vol.22
, pp. 685-708
-
-
Kakuda, T.N.1
-
6
-
-
0032710215
-
Nucleoside reverse transcriptase inhibitor-induced mitochondrial toxicity as an etiology for lipodystrophy
-
Kakuda TN, Brundage RC, Anderson PL, et al: Nucleoside reverse transcriptase inhibitor-induced mitochondrial toxicity as an etiology for lipodystrophy [letter]. AIDS 13:2311-2312, 1999
-
(1999)
AIDS
, vol.13
, pp. 2311-2312
-
-
Kakuda, T.N.1
Brundage, R.C.2
Anderson, P.L.3
-
7
-
-
0034979438
-
Mitochondrial DNA depletion, oxidative stress and mutation: Mechanisms of nucleoside reverse transcriptase inhibitor toxicity
-
Lewis W, Copeland WC, Day B: Mitochondrial DNA depletion, oxidative stress and mutation: Mechanisms of nucleoside reverse transcriptase inhibitor toxicity. Lab Invest 81:777-790, 2001
-
(2001)
Lab Invest
, vol.81
, pp. 777-790
-
-
Lewis, W.1
Copeland, W.C.2
Day, B.3
-
8
-
-
0003299415
-
Hyperlactatemia and Antiretroviral Therapy in the Swiss HIV Cohort Study (SHCS)
-
San Francisco, CA
-
Boubaker K, Sudre P, Flepp M, et al: Hyperlactatemia and Antiretroviral Therapy in the Swiss HIV Cohort Study (SHCS). In the 7th Conference on Retroviruses and Opportunistic Infections, San Francisco, CA, 2000
-
(2000)
7th Conference on Retroviruses and Opportunistic Infections
-
-
Boubaker, K.1
Sudre, P.2
Flepp, M.3
-
9
-
-
0034456943
-
Editorial response: Hyperlactatemia and hepatic steatosis as features of mitochondrial toxicity of nucleoside analogue reverse transcriptase inhibitors
-
Brinkman K: Editorial response: Hyperlactatemia and hepatic steatosis as features of mitochondrial toxicity of nucleoside analogue reverse transcriptase inhibitors. Clin Infect Dis 31:167-169, 2000
-
(2000)
Clin Infect Dis
, vol.31
, pp. 167-169
-
-
Brinkman, K.1
-
10
-
-
0003266761
-
Near-fatal metabolic acidosis, liver failure in mitochondrial (mt) DNA depletion in an HIV-infected child treated with combination antiretroviral therapy (ART)
-
San Francisco, CA
-
Church J, Mitchell W, Gonzalez-Gomez I, et al: Near-fatal metabolic acidosis, liver failure in mitochondrial (mt) DNA depletion in an HIV-infected child treated with combination antiretroviral therapy (ART). In the 7th Conference on Retroviruses and Opportunistic Infections, San Francisco, CA, 2000
-
(2000)
7th Conference on Retroviruses and Opportunistic Infections
-
-
Church, J.1
Mitchell, W.2
Gonzalez-Gomez, I.3
-
11
-
-
0034493575
-
Symptomatic hyperlactataemia: An emerging complication of antiretroviral therapy
-
Gerard Y, Maulin L, Yazdanpanah Y, et al: Symptomatic hyperlactataemia: An emerging complication of antiretroviral therapy. AIDS 14:2723-2730, 2000
-
(2000)
AIDS
, vol.14
, pp. 2723-2730
-
-
Gerard, Y.1
Maulin, L.2
Yazdanpanah, Y.3
-
12
-
-
0035853430
-
Chronic hyperlactatemia in HIV-infected patients taking antiretroviral therapy
-
John M, Moore CB, James IR, et al: Chronic hyperlactatemia in HIV-infected patients taking antiretroviral therapy. AIDS 15:717-723, 2001
-
(2001)
AIDS
, vol.15
, pp. 717-723
-
-
John, M.1
Moore, C.B.2
James, I.R.3
-
13
-
-
0003231017
-
Hyperlactatemia in 20 patients receiving NRTI combination regimens
-
San Francisco, CA
-
Lonergan JT, Havlir D, Behling C, et al: Hyperlactatemia in 20 patients receiving NRTI combination regimens. In the 7th Conference on Retroviruses and Opportunistic Infections, San Francisco, CA, 2000
-
(2000)
7th Conference on Retroviruses and Opportunistic Infections
-
-
Lonergan, J.T.1
Havlir, D.2
Behling, C.3
-
14
-
-
0033985675
-
Lactic acidosis associated with stavudine administration: A report of five cases
-
Mokrzycki MH, Harris C, May H, et al: Lactic acidosis associated with stavudine administration: A report of five cases. Clin Infect Dis 30:198-200, 2000
-
(2000)
Clin Infect Dis
, vol.30
, pp. 198-200
-
-
Mokrzycki, M.H.1
Harris, C.2
May, H.3
-
15
-
-
0028805297
-
Massive hepatic steatosis and lactic acidosis in a patient with AIDS who was receiving zidovudine
-
Olano JP, Borucki MJ, Wen JW, et al: Massive hepatic steatosis and lactic acidosis in a patient with AIDS who was receiving zidovudine. Clin Infect Dis 21:973-976, 1995
-
(1995)
Clin Infect Dis
, vol.21
, pp. 973-976
-
-
Olano, J.P.1
Borucki, M.J.2
Wen, J.W.3
-
16
-
-
0033824325
-
Lactic acidosis in the setting of antiretroviral therapy for the acquired immunodeficiency syndrome. A case report and review of the literature
-
Shaer AJ, Rastegar A: Lactic acidosis in the setting of antiretroviral therapy for the acquired immunodeficiency syndrome. A case report and review of the literature. Am J Nephrol 20:332-338, 2000
-
(2000)
Am J Nephrol
, vol.20
, pp. 332-338
-
-
Shaer, A.J.1
Rastegar, A.2
-
17
-
-
0035835498
-
Elevated lactate levels in hospitalized persons with HIV infection
-
Tantisiriwat W, Tebas P, Polish LB, et al: Elevated lactate levels in hospitalized persons with HIV infection. AIDS Res Hum Retroviruses 17:195-201, 2001
-
(2001)
AIDS Res Hum Retroviruses
, vol.17
, pp. 195-201
-
-
Tantisiriwat, W.1
Tebas, P.2
Polish, L.B.3
-
18
-
-
0035288860
-
Clinical manifestations of mitochondrial toxicity
-
Walker UA: Clinical manifestations of mitochondrial toxicity. J HIV Ther 6:17-21, 2001
-
(2001)
J HIV Ther
, vol.6
, pp. 17-21
-
-
Walker, U.A.1
-
19
-
-
0026046254
-
Mitochondrial ultrastructural and molecular changes induced by zidovudine in rat hearts
-
Lewis W, Papoian T, Gonzalez B, et al: Mitochondrial ultrastructural and molecular changes induced by zidovudine in rat hearts. Lab Invest 65:228-236, 1991
-
(1991)
Lab Invest
, vol.65
, pp. 228-236
-
-
Lewis, W.1
Papoian, T.2
Gonzalez, B.3
-
20
-
-
0026681374
-
Zidovudine induces molecular, biochemical, and ultrastructural changes in rat skeletal muscle mitochondria
-
Lewis W, Gonzalez B, Chomyn A, et al: Zidovudine induces molecular, biochemical, and ultrastructural changes in rat skeletal muscle mitochondria. J Clin Invest 89:1354-1360, 1992
-
(1992)
J Clin Invest
, vol.89
, pp. 1354-1360
-
-
Lewis, W.1
Gonzalez, B.2
Chomyn, A.3
-
21
-
-
0001995913
-
Pathologic changes in the hearts of patients with AIDS
-
Lipshultz SE, ed. New York: Chapman and Hall
-
Lewis W: Pathologic changes in the hearts of patients with AIDS, in Lipshultz SE, ed. Cardiology in AIDS. New York: Chapman and Hall, 1998, pp 233-254
-
(1998)
Cardiology in AIDS
, pp. 233-254
-
-
Lewis, W.1
-
22
-
-
0032189850
-
Adverse effects of reverse transcriptase inhibitors: Mitochondrial toxicity as common pathway
-
Brinkman K, ter Hofstede HJ, Burger DM, et al: Adverse effects of reverse transcriptase inhibitors: Mitochondrial toxicity as common pathway [editorial]. AIDS 12:1735-1744, 1998
-
(1998)
AIDS
, vol.12
, pp. 1735-1744
-
-
Brinkman, K.1
Ter Hofstede, H.J.2
Burger, D.M.3
-
23
-
-
0031025313
-
Depletion of mitochondrial DNA, destruction of mitochondria, and accumulation of lipid droplets result from fialuridine treatment in woodchucks (Marmota monax)
-
Lewis W, Griniuviene B, Tankersley KO, et al: Depletion of mitochondrial DNA, destruction of mitochondria, and accumulation of lipid droplets result from fialuridine treatment in woodchucks (Marmota monax). Lab Invest 76:77-87, 1997
-
(1997)
Lab Invest
, vol.76
, pp. 77-87
-
-
Lewis, W.1
Griniuviene, B.2
Tankersley, K.O.3
-
24
-
-
0037076029
-
Changes in mitochondrial DNA as a marker of nucleoside toxicity in HIV-infected patients
-
Cote HC, Brumme ZL, Craib KJ, et al: Changes in mitochondrial DNA as a marker of nucleoside toxicity in HIV-infected patients. N Engl J Med 346:811-820, 2002
-
(2002)
N Engl J Med
, vol.346
, pp. 811-820
-
-
Cote, H.C.1
Brumme, Z.L.2
Craib, K.J.3
-
25
-
-
0035171192
-
Combined antiretroviral therapy causes cardiomyopathy and elevates plasma lactate in transgenic AIDS mice
-
Lewis W, Haase CP, Raidel SM, et al: Combined antiretroviral therapy causes cardiomyopathy and elevates plasma lactate in transgenic AIDS mice. Lab Invest 81:1527-1536, 2001
-
(2001)
Lab Invest
, vol.81
, pp. 1527-1536
-
-
Lewis, W.1
Haase, C.P.2
Raidel, S.M.3
-
26
-
-
0025274663
-
Mitochondrial myopathy caused by long-term zidovudine therapy
-
Dalakas MC, Illa I, Pezeshkpour GH, et al: Mitochondrial myopathy caused by long-term zidovudine therapy [see comments]. N Engl J Med 322:1098-1105, 1990
-
(1990)
N Engl J Med
, vol.322
, pp. 1098-1105
-
-
Dalakas, M.C.1
Illa, I.2
Pezeshkpour, G.H.3
-
27
-
-
0026356201
-
Abnormal skeletal and cardiac muscle mitochondria induced by zidovudine (AZT) in human muscle in vitro and in an animal model
-
Lamperth L, Dalakas MC, Dagani F, et al: Abnormal skeletal and cardiac muscle mitochondria induced by zidovudine (AZT) in human muscle in vitro and in an animal model. Lab Invest 65:742-751, 1991
-
(1991)
Lab Invest
, vol.65
, pp. 742-751
-
-
Lamperth, L.1
Dalakas, M.C.2
Dagani, F.3
-
28
-
-
0028158398
-
Cardiac mitochondrial DNA polymerase-gamma is inhibited competitively and noncompetitively by phosphorylated zidovudine
-
Lewis W, Simpson JF, Meyer RR: Cardiac mitochondrial DNA polymerase-gamma is inhibited competitively and noncompetitively by phosphorylated zidovudine. Circ Res 74:344-38, 1994
-
(1994)
Circ Res
, vol.74
, pp. 344-438
-
-
Lewis, W.1
Simpson, J.F.2
Meyer, R.R.3
-
29
-
-
0024406638
-
Azidothymidine triphosphate is an inhibitor of both human immunodeficiency virus type 1 reverse transcriptase and DNA polymerase gamma
-
Konig H, Behr E, Lower J, et al: Azidothymidine triphosphate is an inhibitor of both human immunodeficiency virus type 1 reverse transcriptase and DNA polymerase gamma. Antimicrob Agents Chemother 33:2109-2114, 1989
-
(1989)
Antimicrob Agents Chemother
, vol.33
, pp. 2109-2114
-
-
Konig, H.1
Behr, E.2
Lower, J.3
-
30
-
-
1842570096
-
AZT treatment induces molecular and ultrastructural oxidative damage to muscle mitochondria. Prevention by antioxidant vitamins
-
de la Asuncion JG, del Olmo ML, Sastre J, et al: AZT treatment induces molecular and ultrastructural oxidative damage to muscle mitochondria. Prevention by antioxidant vitamins. J Clin Invest 102:4-9, 1998
-
(1998)
J Clin Invest
, vol.102
, pp. 4-9
-
-
De la Asuncion, J.G.1
Del Olmo, M.L.2
Sastre, J.3
-
31
-
-
0034064371
-
Oxidative DNA damage in fetal tissues after transplacental exposure to 3′-azido-3′-deoxythymidine (AZT)
-
Bialkowska A, Bialkowski K, Gerschenson M, et al: Oxidative DNA damage in fetal tissues after transplacental exposure to 3′-azido-3′-deoxythymidine (AZT). Carcinogenesis 21:1059-1062, 2000
-
(2000)
Carcinogenesis
, vol.21
, pp. 1059-1062
-
-
Bialkowska, A.1
Bialkowski, K.2
Gerschenson, M.3
-
32
-
-
0034162611
-
Modulation of glutathione synthetic enzymes by acidic fibroblast growth factor
-
Choi J, Opalenik SR, Wu W, et al: Modulation of glutathione synthetic enzymes by acidic fibroblast growth factor. Arch Biochem Biophys 375:201-209, 2000
-
(2000)
Arch Biochem Biophys
, vol.375
, pp. 201-209
-
-
Choi, J.1
Opalenik, S.R.2
Wu, W.3
-
33
-
-
0034603123
-
Molecular mechanism of decreased glutathione content in human immunodeficiency virus type 1 Tat-transgenic mice
-
Choi J, Liu RM, Kundu RK, et al: Molecular mechanism of decreased glutathione content in human immunodeficiency virus type 1 Tat-transgenic mice. J Biol Chem 275:3693-3698, 2000
-
(2000)
J Biol Chem
, vol.275
, pp. 3693-3698
-
-
Choi, J.1
Liu, R.M.2
Kundu, R.K.3
-
34
-
-
0036087347
-
Targeted myocardial transgenic expression of HIV Tat causes cardiomyopathy and mitochondrial damage
-
Raidel SM, Haase C, Jansen NR, et al: Targeted myocardial transgenic expression of HIV Tat causes cardiomyopathy and mitochondrial damage. Am J Physiol 282:H1672-H1678, 2002
-
(2002)
Am J Physiol
, vol.282
-
-
Raidel, S.M.1
Haase, C.2
Jansen, N.R.3
-
35
-
-
0026782893
-
Mitochondrial function in neurodegeneration and ageing
-
Schapira AH, Cooper JM: Mitochondrial function in neurodegeneration and ageing. Mutat Res 275:133-143, 1992
-
(1992)
Mutat Res
, vol.275
, pp. 133-143
-
-
Schapira, A.H.1
Cooper, J.M.2
-
36
-
-
0026624980
-
Diseases of the mitochondrial DNA
-
Wallace DC: Diseases of the mitochondrial DNA. Annu Rev Biochem 61:1175-1212, 1992
-
(1992)
Annu Rev Biochem
, vol.61
, pp. 1175-1212
-
-
Wallace, D.C.1
-
37
-
-
0022840351
-
A mitochondrial DNA polymerase from embryos of Drosophila melanogaster. Purification, subunit structure, and partial characterization
-
Wernette CM, Kaguni LS: A mitochondrial DNA polymerase from embryos of Drosophila melanogaster. Purification, subunit structure, and partial characterization. J Biol Chem 261:14764-14770, 1986
-
(1986)
J Biol Chem
, vol.261
, pp. 14764-14770
-
-
Wernette, C.M.1
Kaguni, L.S.2
-
38
-
-
0024849684
-
DNA polymerase gamma from Xenopus laevis. I. The identification of a high molecular weight catalytic subunit by a novel DNA polymerase photolabeling procedure
-
Insdorf NF, Bogenhagen DF: DNA polymerase gamma from Xenopus laevis . I. The identification of a high molecular weight catalytic subunit by a novel DNA polymerase photolabeling procedure. J Biol Chem 264:21491-21497, 1989
-
(1989)
J Biol Chem
, vol.264
, pp. 21491-21497
-
-
Insdorf, N.F.1
Bogenhagen, D.F.2
-
39
-
-
0026672705
-
Purification and identification of subunit structure of the human mitochondrial DNA polymerase
-
Gray H, Wong TW: Purification and identification of subunit structure of the human mitochondrial DNA polymerase. J Biol Chem 267:5835-5841, 1992
-
(1992)
J Biol Chem
, vol.267
, pp. 5835-5841
-
-
Gray, H.1
Wong, T.W.2
-
40
-
-
0030991961
-
Accessory subunit of mitochondrial DNA polymerase from Drosophila embryos. Cloning, molecular analysis, and association in the native enzyme
-
Wang Y, Farr CL, Kaguni LS: Accessory subunit of mitochondrial DNA polymerase from Drosophila embryos. Cloning, molecular analysis, and association in the native enzyme. J Biol Chem 272:13640-13646, 1997
-
(1997)
J Biol Chem
, vol.272
, pp. 13640-13646
-
-
Wang, Y.1
Farr, C.L.2
Kaguni, L.S.3
-
41
-
-
0033010856
-
The accessory subunit of Xenopus laevis mitochondrial DNA polymerase gamma increases processivity of the catalytic subunit of human DNA polymerase gamma and is related to class II aminoacyl-tRNA synthetases
-
Carrodeguas JA, Kobayashi R, Lim SE, et al: The accessory subunit of Xenopus laevis mitochondrial DNA polymerase gamma increases processivity of the catalytic subunit of human DNA polymerase gamma and is related to class II aminoacyl-tRNA synthetases. Mol Cell Biol 19:4039-4046, 1999
-
(1999)
Mol Cell Biol
, vol.19
, pp. 4039-4046
-
-
Carrodeguas, J.A.1
Kobayashi, R.2
Lim, S.E.3
-
42
-
-
0033621374
-
The mitochondrial p55 accessory subunit of human DNA polymerase gamma enhances DNA binding, promotes processive DNA synthesis, and confers N-ethylmaleimide resistance
-
Lim SE, Longley MJ, Copeland WC: The mitochondrial p55 accessory subunit of human DNA polymerase gamma enhances DNA binding, promotes processive DNA synthesis, and confers N-ethylmaleimide resistance. J Biol Chem 274:38197-38203, 1999
-
(1999)
J Biol Chem
, vol.274
, pp. 38197-38203
-
-
Lim, S.E.1
Longley, M.J.2
Copeland, W.C.3
-
43
-
-
0012279445
-
Active site mutation in DNA polymerase gamma associated with progressive external ophthalmoplegia causes error-prone DNA synthesis
-
Ponamarev MV, Longley MJ, Nguyen D, et al: Active site mutation in DNA polymerase gamma associated with progressive external ophthalmoplegia causes error-prone DNA synthesis. J Biol Chem 15:15, 2002
-
(2002)
J Biol Chem
, vol.15
, pp. 15
-
-
Ponamarev, M.V.1
Longley, M.J.2
Nguyen, D.3
-
44
-
-
0037007114
-
The accessory subunit of DNA polymerase gamma is essential for mitochondrial DNA maintenance and development in Drosophila melanogaster
-
Iyengar B, Luo N, Farr CL, et al: The accessory subunit of DNA polymerase gamma is essential for mitochondrial DNA maintenance and development in Drosophila melanogaster. Proc Natl Acad Sci U S A 99:4483-4488, 2002
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 4483-4488
-
-
Iyengar, B.1
Luo, N.2
Farr, C.L.3
-
45
-
-
0033362107
-
Repair of mtDNA in vertebrates
-
Bogenhagen DF: Repair of mtDNA in vertebrates. Am J Hum Genet 64:1276-1281, 1999
-
(1999)
Am J Hum Genet
, vol.64
, pp. 1276-1281
-
-
Bogenhagen, D.F.1
-
46
-
-
0026015896
-
mtDNA depletion with variable tissue expression: A novel genetic abnormality in mitochondrial diseases
-
Moraes CT, Shanske S, Tritschler HJ, et al: mtDNA depletion with variable tissue expression: A novel genetic abnormality in mitochondrial diseases. Am J Hum Genet 48:492-501, 1991
-
(1991)
Am J Hum Genet
, vol.48
, pp. 492-501
-
-
Moraes, C.T.1
Shanske, S.2
Tritschler, H.J.3
-
47
-
-
0026587335
-
Mitochondrial genetics: A paradigm for aging and degenerative diseases?
-
Wallace DC: Mitochondrial genetics: A paradigm for aging and degenerative diseases? Science 256:628-632, 1992
-
(1992)
Science
, vol.256
, pp. 628-632
-
-
Wallace, D.C.1
-
48
-
-
0023912295
-
Exonucleolytic proofreading enhances the fidelity of DNA synthesis by chick embryo DNA polymerase-gamma
-
Kunkel TA, Soni A: Exonucleolytic proofreading enhances the fidelity of DNA synthesis by chick embryo DNA polymerase-gamma. J Biol Chem 263:4450-4459, 1988
-
(1988)
J Biol Chem
, vol.263
, pp. 4450-4459
-
-
Kunkel, T.A.1
Soni, A.2
-
49
-
-
0024535480
-
Exonucleolytic proof-reading by a mammalian DNA polymerase
-
Kunkel TA, Mosbaugh DW: Exonucleolytic proof-reading by a mammalian DNA polymerase. Biochemistry 28:988-995, 1989
-
(1989)
Biochemistry
, vol.28
, pp. 988-995
-
-
Kunkel, T.A.1
Mosbaugh, D.W.2
-
50
-
-
0002787372
-
Structural and catalytic features of the mitochondrial DNA polymerase from Drosophila melanogaster embryos
-
Cold Spring Harbor, NY: Cold Spring Harbor Laboratories
-
Kaguni LS, Wernette CM, Conway MC, et al: Structural and catalytic features of the mitochondrial DNA polymerase from Drosophila melanogaster embryos, in Eukaryotic DNA Replication. Cold Spring Harbor, NY: Cold Spring Harbor Laboratories, 1988, pp 425-432
-
(1988)
Eukaryotic DNA Replication
, pp. 425-432
-
-
Kaguni, L.S.1
Wernette, C.M.2
Conway, M.C.3
-
51
-
-
0026028226
-
Depletion of muscle mitochondrial DNA in AIDS patients with zidovudine-induced myopathy
-
Arnaudo E, Dalakas M, Shanske S, et al: Depletion of muscle mitochondrial DNA in AIDS patients with zidovudine-induced myopathy. Lancet 337:508-510, 1991
-
(1991)
Lancet
, vol.337
, pp. 508-510
-
-
Arnaudo, E.1
Dalakas, M.2
Shanske, S.3
-
52
-
-
0029162556
-
Mammalian deoxyribonucleoside kinases
-
Arner ES, Eriksson S: Mammalian deoxyribonucleoside kinases. Pharmacol Ther 67:155-186, 1995
-
(1995)
Pharmacol Ther
, vol.67
, pp. 155-186
-
-
Arner, E.S.1
Eriksson, S.2
-
53
-
-
0033613865
-
Thymidine phosphorylase gene mutations in MNGIE, a human mitochondrial disorder
-
Nishino I, Spinazzola A, Hirano M: Thymidine phosphorylase gene mutations in MNGIE, a human mitochondrial disorder. Science 283:689-692, 1999
-
(1999)
Science
, vol.283
, pp. 689-692
-
-
Nishino, I.1
Spinazzola, A.2
Hirano, M.3
-
54
-
-
0035179561
-
Mutant mitochondrial thymidine kinase in mitochondrial DNA depletion myopathy
-
Saada A, Shaag A, Mandel H, et al: Mutant mitochondrial thymidine kinase in mitochondrial DNA depletion myopathy. Nat Genet 29:342-344, 2001
-
(2001)
Nat Genet
, vol.29
, pp. 342-344
-
-
Saada, A.1
Shaag, A.2
Mandel, H.3
-
55
-
-
0031770320
-
Is the failing heart energy depleted?
-
Katz AM: Is the failing heart energy depleted? Cardiol Clin 16:viii, 633-644, 1998
-
(1998)
Cardiol Clin
, vol.16
-
-
Katz, A.M.1
-
56
-
-
0033525773
-
Mitochondrial diseases in man and mouse
-
Wallace DC: Mitochondrial diseases in man and mouse. Science 283:1482-1488, 1999
-
(1999)
Science
, vol.283
, pp. 1482-1488
-
-
Wallace, D.C.1
-
57
-
-
0028606525
-
Mammalian DNA polymerases alpha, beta, gamma, delta, and epsilon incorporate fialuridine (FIAU) monophosphate into DNA and are inhibited competitively by FIAU triphosphate
-
Lewis W, Meyer RR, Simpson JF, et al: Mammalian DNA polymerases alpha, beta, gamma, delta, and epsilon incorporate fialuridine (FIAU) monophosphate into DNA and are inhibited competitively by FIAU triphosphate. Biochemistry 33:14620-14624, 1994
-
(1994)
Biochemistry
, vol.33
, pp. 14620-14624
-
-
Lewis, W.1
Meyer, R.R.2
Simpson, J.F.3
-
58
-
-
0029978235
-
Fialuridine and its metabolites inhibit DNA polymerase gamma at sites of multiple adjacent analog incorporation, decrease mtDNA abundance, and cause mitochondrial structural defects in cultured hepatoblasts
-
Lewis W, Levine ES, Griniuviene B, et al: Fialuridine and its metabolites inhibit DNA polymerase gamma at sites of multiple adjacent analog incorporation, decrease mtDNA abundance, and cause mitochondrial structural defects in cultured hepatoblasts. Proc Natl Acad Sci U S A 93:3592-3597, 1996
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 3592-3597
-
-
Lewis, W.1
Levine, E.S.2
Griniuviene, B.3
-
59
-
-
0034007233
-
Cardiac dysfunction occurs in the HIV-1 transgenic mouse treated with zidovudine
-
Lewis W, Grupp IL, Grupp G, et al: Cardiac dysfunction occurs in the HIV-1 transgenic mouse treated with zidovudine. Lab Invest 80:187-197, 2000
-
(2000)
Lab Invest
, vol.80
, pp. 187-197
-
-
Lewis, W.1
Grupp, I.L.2
Grupp, G.3
-
60
-
-
0036271671
-
Azidothymidine causes functional and structural destruction of mitochondria, glutathione deficiency and HIV-1 promoter sensitization
-
Yamaguchi T, Katoh I, Kurata S: Azidothymidine causes functional and structural destruction of mitochondria, glutathione deficiency and HIV-1 promoter sensitization. Eur J Biochem 269:2782-2788, 2002
-
(2002)
Eur J Biochem
, vol.269
, pp. 2782-2788
-
-
Yamaguchi, T.1
Katoh, I.2
Kurata, S.3
-
61
-
-
0033951258
-
What is oxidative stress?
-
Betteridge DJ: What is oxidative stress? Metabolism 49:3-8, 2000
-
(2000)
Metabolism
, vol.49
, pp. 3-8
-
-
Betteridge, D.J.1
-
62
-
-
0019848340
-
Hyperoxia increases oxygen radical production in rat lungs and lung mitochondria
-
Freeman BA, Crapo JD: Hyperoxia increases oxygen radical production in rat lungs and lung mitochondria. J Biol Chem 256:10986-10992, 1981
-
(1981)
J Biol Chem
, vol.256
, pp. 10986-10992
-
-
Freeman, B.A.1
Crapo, J.D.2
-
63
-
-
0015882341
-
The mitochondrial generation of hydrogen peroxide. General properties and effect of hyperbaric oxygen
-
Boveris A, Chance B: The mitochondrial generation of hydrogen peroxide. General properties and effect of hyperbaric oxygen. Biochem J 134:707-716, 1973
-
(1973)
Biochem J
, vol.134
, pp. 707-716
-
-
Boveris, A.1
Chance, B.2
-
65
-
-
0020150246
-
Mitochondrial formation of OH radicals by an ubisemiquinone-dependent reaction an alternative pathway to the iron-catalysed Haber-Weiss cycle
-
Nohl H, Jordan W, Hegner D: Mitochondrial formation of OH radicals by an ubisemiquinone-dependent reaction an alternative pathway to the iron-catalysed Haber-Weiss cycle. Hoppe Seylers Z Physiol Chem 363:599-607, 1982
-
(1982)
Hoppe Seylers Z Physiol Chem
, vol.363
, pp. 599-607
-
-
Nohl, H.1
Jordan, W.2
Hegner, D.3
-
66
-
-
0028870087
-
Reactive oxygen species produced by liver mitochondria of rats in sepsis
-
Taylor DE, Ghio AJ, Piantadosi CA: Reactive oxygen species produced by liver mitochondria of rats in sepsis. Arch Biochem Biophys 316:70-76, 1995
-
(1995)
Arch Biochem Biophys
, vol.316
, pp. 70-76
-
-
Taylor, D.E.1
Ghio, A.J.2
Piantadosi, C.A.3
-
67
-
-
0019319179
-
Mitochondrial iron not bound in heme and iron-sulfur centers. Estimation, compartmentation and redox state
-
Tangeras A, Flatmark T, Backstrom D, et al: Mitochondrial iron not bound in heme and iron-sulfur centers. Estimation, compartmentation and redox state. Biochim Biophys Acta 589:162-175, 1980
-
(1980)
Biochim Biophys Acta
, vol.589
, pp. 162-175
-
-
Tangeras, A.1
Flatmark, T.2
Backstrom, D.3
-
68
-
-
0027491617
-
The inactivation of Fe-S cluster containing hydro-lyases by superoxide
-
Flint DH, Tuminello JF, Emptage MH: The inactivation of Fe-S cluster containing hydro-lyases by superoxide. J Biol Chem 268:22369-22376, 1993
-
(1993)
J Biol Chem
, vol.268
, pp. 22369-22376
-
-
Flint, D.H.1
Tuminello, J.F.2
Emptage, M.H.3
-
69
-
-
0035968164
-
Differential incorporation and removal of antiviral deoxynucleotides by human DNA polymerase gamma
-
Lim SE, Copeland WC: Differential incorporation and removal of antiviral deoxynucleotides by human DNA polymerase gamma. J Biol Chem 276:23616-23623, 2001
-
(2001)
J Biol Chem
, vol.276
, pp. 23616-23623
-
-
Lim, S.E.1
Copeland, W.C.2
-
70
-
-
0034036986
-
Nitric oxide as a competitive inhibitor of oxygen consumption in the mitochondrial respiratory chain
-
Brown GC: Nitric oxide as a competitive inhibitor of oxygen consumption in the mitochondrial respiratory chain. Acta Physiol Scand 168:667-674, 2000
-
(2000)
Acta Physiol Scand
, vol.168
, pp. 667-674
-
-
Brown, G.C.1
-
71
-
-
0029805172
-
Nitric oxide, superoxide, and peroxynitrite: The good, the bad, and ugly
-
Beckman JS, Koppenol WH: Nitric oxide, superoxide, and peroxynitrite: The good, the bad, and ugly. Am J Physiol 271:C1424-C1437, 1996
-
(1996)
Am J Physiol
, vol.271
-
-
Beckman, J.S.1
Koppenol, W.H.2
-
72
-
-
0025874048
-
Peroxynitrite-induced membrane lipid peroxidation: The cytotoxic potential of superoxide and nitric oxide
-
Radi R, Beckman JS, Bush KM, et al: Peroxynitrite-induced membrane lipid peroxidation: The cytotoxic potential of superoxide and nitric oxide. Arch Biochem Biophys 288:481-487, 1991
-
(1991)
Arch Biochem Biophys
, vol.288
, pp. 481-487
-
-
Radi, R.1
Beckman, J.S.2
Bush, K.M.3
-
74
-
-
0029928984
-
Immunolocalization of cellular glutathione peroxidase in adult rat lungs and quantitative analysis after postembedding immunogold labeling
-
Asayama K, Yokota S, Dobashi K, et al: Immunolocalization of cellular glutathione peroxidase in adult rat lungs and quantitative analysis after postembedding immunogold labeling. Histochem Cell Biol 105:383-389, 1996
-
(1996)
Histochem Cell Biol
, vol.105
, pp. 383-389
-
-
Asayama, K.1
Yokota, S.2
Dobashi, K.3
-
75
-
-
0031018005
-
Role of glutathione peroxidase and phospholipid hydroperoxide glutathione peroxidase in the reduction of lysophospholipid hydroperoxides
-
Marinho HS, Antunes F, Pinto RE: Role of glutathione peroxidase and phospholipid hydroperoxide glutathione peroxidase in the reduction of lysophospholipid hydroperoxides. Free Radic Biol Med 22:871-883, 1997
-
(1997)
Free Radic Biol Med
, vol.22
, pp. 871-883
-
-
Marinho, H.S.1
Antunes, F.2
Pinto, R.E.3
-
76
-
-
0022394280
-
The importance of free radicals and catalytic metal ions in human diseases
-
Halliwell B, Gutteridge JM: The importance of free radicals and catalytic metal ions in human diseases. Mol Aspects Med 8:89-193, 1985
-
(1985)
Mol Aspects Med
, vol.8
, pp. 89-193
-
-
Halliwell, B.1
Gutteridge, J.M.2
-
77
-
-
0033637571
-
Fetal patas monkeys sustain mitochondrial toxicity as a result of in utero zidovudine exposure
-
Gerschenson M, Poirier MC: Fetal patas monkeys sustain mitochondrial toxicity as a result of in utero zidovudine exposure. Ann N Y Acad Sci 918:269-281, 2000
-
(2000)
Ann N Y Acad Sci
, vol.918
, pp. 269-281
-
-
Gerschenson, M.1
Poirier, M.C.2
-
79
-
-
0024541837
-
Mitochondrial DNA mutations as an important contributor to ageing and degenerative diseases
-
Linnane AW, Marzuki S, Ozawa T, et al: Mitochondrial DNA mutations as an important contributor to ageing and degenerative diseases. Lancet 1:642-645, 1989
-
(1989)
Lancet
, vol.1
, pp. 642-645
-
-
Linnane, A.W.1
Marzuki, S.2
Ozawa, T.3
-
80
-
-
0014127831
-
Inactivating DNA alterations induced by peroxides and peroxide-producing agents
-
Freese EB, Gerson J, Taber H, et al: Inactivating DNA alterations induced by peroxides and peroxide-producing agents. Mutat Res 4:517-531, 1967
-
(1967)
Mutat Res
, vol.4
, pp. 517-531
-
-
Freese, E.B.1
Gerson, J.2
Taber, H.3
-
81
-
-
0019532613
-
DNA strand scission by enzymically generated oxygen radicals
-
Brawn K, Fridovich I: DNA strand scission by enzymically generated oxygen radicals. Arch Biochem Biophys 206:414-419, 1981
-
(1981)
Arch Biochem Biophys
, vol.206
, pp. 414-419
-
-
Brawn, K.1
Fridovich, I.2
-
82
-
-
0029922989
-
Evaluation of the relative contribution of nitric oxide and peroxynitrite to the suppression of mitochondrial respiration in immunostimulated macrophages using a manganese mesoporphyrin superoxide dismutase mimetic and peroxynitrite scavenger
-
Szabo C, Day BJ, Salzman AL: Evaluation of the relative contribution of nitric oxide and peroxynitrite to the suppression of mitochondrial respiration in immunostimulated macrophages using a manganese mesoporphyrin superoxide dismutase mimetic and peroxynitrite scavenger. FEBS Lett 381:82-86, 1996
-
(1996)
FEBS Lett
, vol.381
, pp. 82-86
-
-
Szabo, C.1
Day, B.J.2
Salzman, A.L.3
-
83
-
-
0029979758
-
Base modification and strand breakage in isolated calf thymus DNA and in DNA from human skin epidermal keratinocytes exposed to peroxynitrite or 3-morpholinosydnonimine
-
Spencer JP, Wong J, Jenner A, et al: Base modification and strand breakage in isolated calf thymus DNA and in DNA from human skin epidermal keratinocytes exposed to peroxynitrite or 3-morpholinosydnonimine. Chem Res Toxicol 9:1152-1158, 1996
-
(1996)
Chem Res Toxicol
, vol.9
, pp. 1152-1158
-
-
Spencer, J.P.1
Wong, J.2
Jenner, A.3
-
84
-
-
0029924533
-
Degeneration of human oncogenes and mitochondrial genes occurs in cells that exhibit age-related pathology
-
Cortopassi G, Liu Y, Hutchin T: Degeneration of human oncogenes and mitochondrial genes occurs in cells that exhibit age-related pathology. Exp Gerontol 31:253-265, 1996
-
(1996)
Exp Gerontol
, vol.31
, pp. 253-265
-
-
Cortopassi, G.1
Liu, Y.2
Hutchin, T.3
-
85
-
-
0024266283
-
Do mitochondrial DNA fragments promote cancer and aging?
-
Richter C: Do mitochondrial DNA fragments promote cancer and aging? [see comments]. FEBS Lett 241:1-5, 1988
-
(1988)
FEBS Lett
, vol.241
, pp. 1-5
-
-
Richter, C.1
-
86
-
-
0023811053
-
Normal oxidative damage to mitochondrial and nuclear DNA is extensive
-
Richter C, Park JW, Ames BN: Normal oxidative damage to mitochondrial and nuclear DNA is extensive. Proc Natl Acad Sci U S A 85:6465-6467, 1988
-
(1988)
Proc Natl Acad Sci U S A
, vol.85
, pp. 6465-6467
-
-
Richter, C.1
Park, J.W.2
Ames, B.N.3
-
87
-
-
0027055332
-
Age-associated oxygen damage and mutations in mitochondrial DNA in human hearts
-
Hayakawa M, Hattori K, Sugiyama S, et al: Age-associated oxygen damage and mutations in mitochondrial DNA in human hearts. Biochem Biophys Res Commun 189:979-985, 1992
-
(1992)
Biochem Biophys Res Commun
, vol.189
, pp. 979-985
-
-
Hayakawa, M.1
Hattori, K.2
Sugiyama, S.3
-
88
-
-
0028266940
-
DNA replication fidelity with 8-oxodeoxyguanosine triphosphate
-
Pavlov YI, Minnick DT, Izuta S, et al: DNA replication fidelity with 8-oxodeoxyguanosine triphosphate. Biochemistry 33:4695-4701, 1994
-
(1994)
Biochemistry
, vol.33
, pp. 4695-4701
-
-
Pavlov, Y.I.1
Minnick, D.T.2
Izuta, S.3
-
89
-
-
0031032817
-
Mitochondrial DNA damage is more extensive and persists longer than nuclear DNA damage in human cells following oxidative stress
-
Yakes FM, Van Houten B: Mitochondrial DNA damage is more extensive and persists longer than nuclear DNA damage in human cells following oxidative stress. Proc Natl Acad Sci U S A 94:514-519, 1997
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 514-519
-
-
Yakes, F.M.1
Van Houten, B.2
-
90
-
-
0027171266
-
Oxidants, antioxidants, and the degenerative diseases of aging
-
Ames BN, Shigenaga MK, Hagen TM: Oxidants, antioxidants, and the degenerative diseases of aging. Proc Natl Acad Sci U S A 90:7915-7922, 1993
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, pp. 7915-7922
-
-
Ames, B.N.1
Shigenaga, M.K.2
Hagen, T.M.3
-
91
-
-
0031952184
-
Efficient repair of abasic sites in DNA by mitochondrial enzymes
-
Pinz KG, Bogenhagen DF: Efficient repair of abasic sites in DNA by mitochondrial enzymes. Mol Cell Biol 18:1257-1265, 1998
-
(1998)
Mol Cell Biol
, vol.18
, pp. 1257-1265
-
-
Pinz, K.G.1
Bogenhagen, D.F.2
-
92
-
-
0020066839
-
Is cell aging caused by respiration-dependent injury to the mitochondrial genome?
-
Fleming JE, Miquel J, Cottrell SF, et al: Is cell aging caused by respiration-dependent injury to the mitochondrial genome? Gerontology 28:44-53, 1982
-
(1982)
Gerontology
, vol.28
, pp. 44-53
-
-
Fleming, J.E.1
Miquel, J.2
Cottrell, S.F.3
-
93
-
-
0023647116
-
Misreading of DNA templates containing 8-hydroxydeoxyguanosine at the modified base and at adjacent residues
-
Kuchino Y, Mori F, Kasai H, et al: Misreading of DNA templates containing 8-hydroxydeoxyguanosine at the modified base and at adjacent residues. Nature 327:77-79, 1987
-
(1987)
Nature
, vol.327
, pp. 77-79
-
-
Kuchino, Y.1
Mori, F.2
Kasai, H.3
-
94
-
-
0025758425
-
Age-dependent increase in deleted mitochondrial DNA in the human heart: Possible contributory factor to presbycardia
-
Hattori K, Tanaka M, Sugiyama S, et al: Age-dependent increase in deleted mitochondrial DNA in the human heart: Possible contributory factor to presbycardia. Am Heart J 121:1735-1742, 1991
-
(1991)
Am Heart J
, vol.121
, pp. 1735-1742
-
-
Hattori, K.1
Tanaka, M.2
Sugiyama, S.3
-
95
-
-
0026737692
-
Mitochondrial DNA mutation and the ageing process: Bioenergy and pharmacological intervention
-
Linnane AW, Zhang C, Baumer A, et al: Mitochondrial DNA mutation and the ageing process: Bioenergy and pharmacological intervention. Mutat Res 275:195-208, 1992
-
(1992)
Mutat Res
, vol.275
, pp. 195-208
-
-
Linnane, A.W.1
Zhang, C.2
Baumer, A.3
-
96
-
-
0024366601
-
Cytochrome-c-oxidase deficient cardiomyocytes in the human heart - An age-related phenomenon. A histochemical ultracytochemical study
-
Muller-Hocker J: Cytochrome-c-oxidase deficient cardiomyocytes in the human heart - an age-related phenomenon. A histochemical ultracytochemical study. Am J Pathol 134:1167-1173, 1989
-
(1989)
Am J Pathol
, vol.134
, pp. 1167-1173
-
-
Muller-Hocker, J.1
-
97
-
-
0000226527
-
Mitochondrial toxicity of NRTI analogs
-
Parker WB, Cheng YC: Mitochondrial toxicity of NRTI analogs. J NIH Res 6:57-61, 1994
-
(1994)
J NIH Res
, vol.6
, pp. 57-61
-
-
Parker, W.B.1
Cheng, Y.C.2
-
98
-
-
0035968250
-
Insights into the molecular mechanism of mitochondrial toxicity by AIDS drugs
-
Feng JY, Johnson AA, Johnson KA, et al: Insights into the molecular mechanism of mitochondrial toxicity by AIDS drugs. J Biol Chem 276:23832-23837, 2001
-
(2001)
J Biol Chem
, vol.276
, pp. 23832-23837
-
-
Feng, J.Y.1
Johnson, A.A.2
Johnson, K.A.3
-
99
-
-
0025139031
-
Inhibitory effects of 2′-fluorinated arabinosyl-pyrimidine nucleosides on woodchuck hepatitis virus replication in chronically infected woodchucks
-
Fourel I, Hantz O, Watanabe KA, et al: Inhibitory effects of 2′-fluorinated arabinosyl-pyrimidine nucleosides on woodchuck hepatitis virus replication in chronically infected woodchucks. Antimicrob Agents Chemother 34:473-475, 1990
-
(1990)
Antimicrob Agents Chemother
, vol.34
, pp. 473-475
-
-
Fourel, I.1
Hantz, O.2
Watanabe, K.A.3
-
100
-
-
0029077056
-
Efficient incorporation of anti-HIV deoxynucleotides by recombinant yeast mitochondrial DNA polymerase
-
Eriksson S, Xu B, Clayton DA: Efficient incorporation of anti-HIV deoxynucleotides by recombinant yeast mitochondrial DNA polymerase. J Biol Chem 270:18929-18934, 1995
-
(1995)
J Biol Chem
, vol.270
, pp. 18929-18934
-
-
Eriksson, S.1
Xu, B.2
Clayton, D.A.3
-
101
-
-
0026355725
-
Properties of the 3′ to 5′ exonuclease associated with porcine liver DNA polymerase gamma. Substrate specificity, product analysis, inhibition, and kinetics of terminal excision
-
Longley MJ, Mosbaugh DW: Properties of the 3′ to 5′ exonuclease associated with porcine liver DNA polymerase gamma. Substrate specificity, product analysis, inhibition, and kinetics of terminal excision. J Biol Chem 266:24702-24711, 1991
-
(1991)
J Biol Chem
, vol.266
, pp. 24702-24711
-
-
Longley, M.J.1
Mosbaugh, D.W.2
-
102
-
-
0012316858
-
Triphosphorylated fialuridine and metabolites inhibit cardiac mitochondrial DNA polymerase gamma (DNA polymerase-gamma): Alternative substrates for thymidine triphosphate (dTTP)
-
Lewis W, Tankersley KO: Triphosphorylated fialuridine and metabolites inhibit cardiac mitochondrial DNA polymerase gamma (DNA polymerase-gamma): Alternative substrates for thymidine triphosphate (dTTP). Circulation 92:1186, 1995
-
(1995)
Circulation
, vol.92
, pp. 1186
-
-
Lewis, W.1
Tankersley, K.O.2
-
103
-
-
0028865886
-
The intracellular phosphorylation of (-)-2′-deoxy-3′-thiacytidine (3TC) and the incorporation of 3TC 5′-monophosphate into DNA by HIV-1 reverse transcriptase and human DNA polymerase gamma
-
Gray NM, Marr CL, Penn CR, et al: The intracellular phosphorylation of (-)-2′-deoxy-3′-thiacytidine (3TC) and the incorporation of 3TC 5′-monophosphate into DNA by HIV-1 reverse transcriptase and human DNA polymerase gamma. Biochem Pharmacol 50:1043-1051, 1995
-
(1995)
Biochem Pharmacol
, vol.50
, pp. 1043-1051
-
-
Gray, N.M.1
Marr, C.L.2
Penn, C.R.3
-
104
-
-
0028148674
-
Effects of antiviral nucleoside analogs on human DNA polymerases and mitochondrial DNA synthesis
-
Martin JL, Brown CE, Matthews-Davis N, et al: Effects of antiviral nucleoside analogs on human DNA polymerases and mitochondrial DNA synthesis. Antimicrob Agents Chemother 38:2743-2749, 1994
-
(1994)
Antimicrob Agents Chemother
, vol.38
, pp. 2743-2749
-
-
Martin, J.L.1
Brown, C.E.2
Matthews-Davis, N.3
-
105
-
-
0025366021
-
Zidovudine intolerance
-
Groopman JE: Zidovudine intolerance. Rev Infect Dis 12:S500-S506, 1990 (suppl 5)
-
(1990)
Rev Infect Dis
, vol.12
, Issue.SUPPL. 5
-
-
Groopman, J.E.1
-
106
-
-
0025165388
-
Myopathy with human immunodeficiency virus type 1 (HIV-1) infection: HIV-1 or zidovudine?
-
Till M, MacDonell KB: Myopathy with human immunodeficiency virus type 1 (HIV-1) infection: HIV-1 or zidovudine? Ann Intern Med 113:492-494, 1990
-
(1990)
Ann Intern Med
, vol.113
, pp. 492-494
-
-
Till, M.1
MacDonell, K.B.2
-
107
-
-
0028229152
-
Mitochondrial DNA diseases: Histological and cellular studies
-
Shoubridge EA: Mitochondrial DNA diseases: Histological and cellular studies. J Bioenerg Biomembr 26:301-310, 1994
-
(1994)
J Bioenerg Biomembr
, vol.26
, pp. 301-310
-
-
Shoubridge, E.A.1
-
108
-
-
0026332740
-
Ultrastructural characteristics and DNA immunocytochemistry in human immunodeficiency virus and zidovudine-associated myopathies
-
Pezeshkpour G, Illa I, Dalakas MC: Ultrastructural characteristics and DNA immunocytochemistry in human immunodeficiency virus and zidovudine-associated myopathies. Hum Pathol 22:1281-1288, 1991
-
(1991)
Hum Pathol
, vol.22
, pp. 1281-1288
-
-
Pezeshkpour, G.1
Illa, I.2
Dalakas, M.C.3
-
109
-
-
0028221762
-
Zidovudine-induced mitochondrial myopathy is associated with muscle carnitine deficiency and lipid storage
-
Dalakas MC, Leon-Monzon ME, Bernardini I, et al: Zidovudine-induced mitochondrial myopathy is associated with muscle carnitine deficiency and lipid storage [see comments]. Ann Neurol 35:482-487, 1994
-
(1994)
Ann Neurol
, vol.35
, pp. 482-487
-
-
Dalakas, M.C.1
Leon-Monzon, M.E.2
Bernardini, I.3
-
110
-
-
0027417551
-
Mitochondrial myopathy associated with chronic zidovudine therapy in AIDS
-
Peters BS, Winer J, Landon DN, et al: Mitochondrial myopathy associated with chronic zidovudine therapy in AIDS. QJM 86:5-15, 1993
-
(1993)
QJM
, vol.86
, pp. 5-15
-
-
Peters, B.S.1
Winer, J.2
Landon, D.N.3
-
111
-
-
0002063598
-
Myopathies and neuropathies in HIV-infected adults and children
-
Pizzo P, Wilfert CM, eds. Baltimore, MD: Williams and Wilkins
-
Jay C, Dalakas MC: Myopathies and neuropathies in HIV-infected adults and children, in Pizzo P, Wilfert CM, eds. Pediatric AIDS. Baltimore, MD: Williams and Wilkins, 1994, pp 559-573
-
(1994)
Pediatric AIDS
, pp. 559-573
-
-
Jay, C.1
Dalakas, M.C.2
-
112
-
-
0023857703
-
Severe polymyositis-like syndrome associated with zidovudine therapy of AIDS and ARC
-
Bessen LJ, Greene JB, Louie E, et al: Severe polymyositis-like syndrome associated with zidovudine therapy of AIDS and ARC [letter]. N Engl J Med 318:708, 1988
-
(1988)
N Engl J Med
, vol.318
, pp. 708
-
-
Bessen, L.J.1
Greene, J.B.2
Louie, E.3
-
113
-
-
0029159782
-
Metabolic abnormalities in skeletal muscle of patients receiving zidovudine therapy observed by 31P in vivo magnetic resonance spectroscopy
-
Sinnwell TM, Sivakumar K, Soueidan S, et al: Metabolic abnormalities in skeletal muscle of patients receiving zidovudine therapy observed by 31P in vivo magnetic resonance spectroscopy. J Clin Invest 96:126-131, 1995
-
(1995)
J Clin Invest
, vol.96
, pp. 126-131
-
-
Sinnwell, T.M.1
Sivakumar, K.2
Soueidan, S.3
-
114
-
-
0026326871
-
Partial cytochrome c oxidase deficiency and cytoplasmic bodies in patients with zidovudine myopathy
-
Chariot P, Gherardi R: Partial cytochrome c oxidase deficiency and cytoplasmic bodies in patients with zidovudine myopathy. Neuromuscul Disord 1:357-363, 1991
-
(1991)
Neuromuscul Disord
, vol.1
, pp. 357-363
-
-
Chariot, P.1
Gherardi, R.2
-
115
-
-
0028204434
-
Determination of the blood lactate: Pyruvate ratio as a noninvasive test for the diagnosis of zidovudine myopathy
-
Chariot P, Monnet I, Mouchet M, et al: Determination of the blood lactate: pyruvate ratio as a noninvasive test for the diagnosis of zidovudine myopathy. Arthritis Rheum 37:583-586, 1994
-
(1994)
Arthritis Rheum
, vol.37
, pp. 583-586
-
-
Chariot, P.1
Monnet, I.2
Mouchet, M.3
-
116
-
-
0026564682
-
Cardiomyopathy associated with antiretroviral therapy in patients with HIV infection: A report of six cases
-
Herskowitz A, Willoughby SB, Baughman KL, et al: Cardiomyopathy associated with antiretroviral therapy in patients with HIV infection: A report of six cases. Ann Intern Med 116:311-313, 1992
-
(1992)
Ann Intern Med
, vol.116
, pp. 311-313
-
-
Herskowitz, A.1
Willoughby, S.B.2
Baughman, K.L.3
-
117
-
-
0034643399
-
Underlying causes and long-term survival in patients with initially unexplained cardiomyopathy
-
Felker GM, Thompson RE, Hare JM, et al: Underlying causes and long-term survival in patients with initially unexplained cardiomyopathy [see comments]. N Engl J Med 342:1077-1084, 2000
-
(2000)
N Engl J Med
, vol.342
, pp. 1077-1084
-
-
Felker, G.M.1
Thompson, R.E.2
Hare, J.M.3
-
118
-
-
38249013430
-
Dilated cardiomyopathy in a zidovudine-treated AIDS patient
-
d'Amati G, Kwan W, Lewis W: Dilated cardiomyopathy in a zidovudine-treated AIDS patient. Cardiovasc Pathol 1:317-320, 1992
-
(1992)
Cardiovasc Pathol
, vol.1
, pp. 317-320
-
-
D'Amati, G.1
Kwan, W.2
Lewis, W.3
-
119
-
-
0026774360
-
Cardiac structure and function in children with human immunodeficiency virus infection treated with zidovudine
-
Lipshultz SE, Orav EJ, Sanders SP, et al: Cardiac structure and function in children with human immunodeficiency virus infection treated with zidovudine [see comments]. N Engl J Med 327:1260-1265, 1992
-
(1992)
N Engl J Med
, vol.327
, pp. 1260-1265
-
-
Lipshultz, S.E.1
Orav, E.J.2
Sanders, S.P.3
-
120
-
-
0034648743
-
Absence of cardiac toxicity of zidovudine in infants. Pediatric Pulmonary and Cardiac Complications of Vertically Transmitted HIV Infection Study Group
-
Lipshultz SE, Easley KA, Orav EJ, et al: Absence of cardiac toxicity of zidovudine in infants. Pediatric Pulmonary and Cardiac Complications of Vertically Transmitted HIV Infection Study Group [see comments]. N Engl J Med 343:759-766, 2000
-
(2000)
N Engl J Med
, vol.343
, pp. 759-766
-
-
Lipshultz, S.E.1
Easley, K.A.2
Orav, E.J.3
-
121
-
-
0029161929
-
Effect of zidovudine and didanosine treatment on heart function in children infected with human immunodeficiency virus
-
Domanski MJ, Sloas MM, Follmann DA, et al: Effect of zidovudine and didanosine treatment on heart function in children infected with human immunodeficiency virus [see comments]. J Pediatr 127:137-146, 1995
-
(1995)
J Pediatr
, vol.127
, pp. 137-146
-
-
Domanski, M.J.1
Sloas, M.M.2
Follmann, D.A.3
-
122
-
-
0034192228
-
Fetal mitochondrial heart and skeletal muscle damage in Erythrocebus patas monkeys exposed in utero to 3′-azido-3′-deoxythymidine
-
Gerschenson M, Erhart SW, Paik CY, et al: Fetal mitochondrial heart and skeletal muscle damage in Erythrocebus patas monkeys exposed in utero to 3′-azido-3′-deoxythymidine. AIDS Res Hum Retro-viruses 16:635-644, 2000
-
(2000)
AIDS Res Hum Retro-viruses
, vol.16
, pp. 635-644
-
-
Gerschenson, M.1
Erhart, S.W.2
Paik, C.Y.3
-
123
-
-
0025729392
-
Effect of anti-human immunodeficiency virus nucleoside analogs on mitochondrial DNA and its implication for delayed toxicity
-
Chen CH, Vazquez-Padua M, Cheng YC: Effect of anti-human immunodeficiency virus nucleoside analogs on mitochondrial DNA and its implication for delayed toxicity. Mol Pharmacol 39:625-628, 1991
-
(1991)
Mol Pharmacol
, vol.39
, pp. 625-628
-
-
Chen, C.H.1
Vazquez-Padua, M.2
Cheng, Y.C.3
-
124
-
-
0024521381
-
Studies on the inhibition of mitochondrial DNA replication by 3′-azido-3′-deoxythymidine and other dideoxynucleoside analogs which inhibit HIV-1 replication
-
Simpson MV, Chin CD, Keilbaugh SA, et al: Studies on the inhibition of mitochondrial DNA replication by 3′-azido-3′-deoxythymidine and other dideoxynucleoside analogs which inhibit HIV-1 replication. Biochem Pharmacol 38:1033-1036, 1989
-
(1989)
Biochem Pharmacol
, vol.38
, pp. 1033-1036
-
-
Simpson, M.V.1
Chin, C.D.2
Keilbaugh, S.A.3
-
125
-
-
0024381627
-
Delayed cytotoxicity and selective loss of mitochondrial DNA in cells treated with the anti-human immunodeficiency virus compound 2′,3′-dideoxycytidine
-
Chen CH, Cheng YC: Delayed cytotoxicity and selective loss of mitochondrial DNA in cells treated with the anti-human immunodeficiency virus compound 2′,3′-dideoxycytidine. J Biol Chem 264:11934-11937, 1989
-
(1989)
J Biol Chem
, vol.264
, pp. 11934-11937
-
-
Chen, C.H.1
Cheng, Y.C.2
-
126
-
-
0028609053
-
Zidovudine causes early increases in mitochondrial ribonucleic acid abundance and induces ultrastructural changes in cultured mouse muscle cells
-
d'Amati G, Lewis W: Zidovudine causes early increases in mitochondrial ribonucleic acid abundance and induces ultrastructural changes in cultured mouse muscle cells. Lab Invest 71:879-884, 1994
-
(1994)
Lab Invest
, vol.71
, pp. 879-884
-
-
D'Amati, G.1
Lewis, W.2
-
127
-
-
0028104333
-
The effect of L-carnitine on the AZT-induced destruction of human myotubes. Part II: Treatment with L-carnitine improves the AZT-induced changes and prevents further destruction
-
Semino-Mora MC, Leon-Monzon ME, Dalakas MC: The effect of L-carnitine on the AZT-induced destruction of human myotubes. Part II: Treatment with L-carnitine improves the AZT-induced changes and prevents further destruction. Lab Invest 71:773-781, 1994
-
(1994)
Lab Invest
, vol.71
, pp. 773-781
-
-
Semino-Mora, M.C.1
Leon-Monzon, M.E.2
Dalakas, M.C.3
-
128
-
-
0028719493
-
Histochemical and ultrastructural changes induced by zidovudine in mitochondria of rat cardiac muscle
-
Corcuera Pindado MT, Lopez Bravo A, Martinez-Rodriguez R, et al: Histochemical and ultrastructural changes induced by zidovudine in mitochondria of rat cardiac muscle. Eur J Histochem 38:311-318, 1994
-
(1994)
Eur J Histochem
, vol.38
, pp. 311-318
-
-
Corcuera Pindado, M.T.1
Lopez Bravo, A.2
Martinez-Rodriguez, R.3
-
129
-
-
4244001403
-
Zidovudine mitochondriopathy of hamster quadriceps muscle
-
abstr
-
Reyes MG, Casanova J, Varricchio F: Zidovudine mitochondriopathy of hamster quadriceps muscle. Lab Invest 64:89A, 1991 (abstr)
-
(1991)
Lab Invest
, vol.64
-
-
Reyes, M.G.1
Casanova, J.2
Varricchio, F.3
-
130
-
-
0028771094
-
Deaths in US fialuridine trial
-
Brahams D: Deaths in US fialuridine trial [news]. Lancet 343:1494-1495, 1994
-
(1994)
Lancet
, vol.343
, pp. 1494-1495
-
-
Brahams, D.1
-
131
-
-
0028306103
-
Hepatitis study. Drug trial deaths deemed unavoidable
-
Marshall E: Hepatitis study. Drug trial deaths deemed unavoidable [news]. Science 264:1530, 1994
-
(1994)
Science
, vol.264
, pp. 1530
-
-
Marshall, E.1
-
132
-
-
0028258919
-
US agencies split over inquiry into effects of radiation experiments
-
Macilwain C: US agencies split over inquiry into effects of radiation experiments [news]. Nature 368:781, 1994
-
(1994)
Nature
, vol.368
, pp. 781
-
-
Macilwain, C.1
-
133
-
-
0028861575
-
Cellular and molecular events leading to mitochondrial toxicity of 1-(2-deoxy-2-fluoro-1-beta-D-arabinofuranosyl)-5-iodouracil in human liver cells
-
Cui L, Yoon S, Schinazi RF, et al: Cellular and molecular events leading to mitochondrial toxicity of 1-(2-deoxy-2-fluoro-1-beta-D-arabinofuranosyl)-5-iodouracil in human liver cells. J Clin Invest 95:555-563, 1995
-
(1995)
J Clin Invest
, vol.95
, pp. 555-563
-
-
Cui, L.1
Yoon, S.2
Schinazi, R.F.3
-
134
-
-
4243962744
-
The thymidine analogs fialuridine and zidovidine inhibit mitochondrial energy metabolism in cultured hepatoblasts
-
abstr
-
Levine ES, Lewis W: The thymidine analogs fialuridine and zidovidine inhibit mitochondrial energy metabolism in cultured hepatoblasts. FASEB J 9:A1398, 1995 (abstr)
-
(1995)
FASEB J
, vol.9
-
-
Levine, E.S.1
Lewis, W.2
-
135
-
-
0028567822
-
Toxicity, metabolism, DNA incorporation with lack of repair, and lactate production for 1-(2′-fluoro-2′-deoxy-beta-D-arabinofuranosyl)-5-iodouracil in U-937 and MOLT-4 cells
-
Klecker RW, Katki AG, Collins JM: Toxicity, metabolism, DNA incorporation with lack of repair, and lactate production for 1-(2′-fluoro-2′-deoxy-beta-D-arabinofuranosyl)-5-iodouracil in U-937 and MOLT-4 cells. Mol Pharmacol 46:1204-1209, 1994
-
(1994)
Mol Pharmacol
, vol.46
, pp. 1204-1209
-
-
Klecker, R.W.1
Katki, A.G.2
Collins, J.M.3
-
136
-
-
17344366353
-
Antiviral activity and toxicity of fialuridine in the woodchuck model of hepatitis B virus infection
-
Tennant BC, Baldwin BH, Graham LA, et al: Antiviral activity and toxicity of fialuridine in the woodchuck model of hepatitis B virus infection. Hepatology 28:179-191, 1998
-
(1998)
Hepatology
, vol.28
, pp. 179-191
-
-
Tennant, B.C.1
Baldwin, B.H.2
Graham, L.A.3
-
137
-
-
0027510616
-
Hepatomegaly with severe steatosis in HIV-seropositive patients
-
Freiman JP, Helfert KE, Hamrell MR, et al: Hepatomegaly with severe steatosis in HIV-seropositive patients. AIDS 7:379-385, 1993
-
(1993)
AIDS
, vol.7
, pp. 379-385
-
-
Freiman, J.P.1
Helfert, K.E.2
Hamrell, M.R.3
-
138
-
-
0027388795
-
Lactic acidosis complicating the acquired immunodeficiency syndrome
-
Chattha G, Arieff AI, Cummings C, et al: Lactic acidosis complicating the acquired immunodeficiency syndrome [see comments]. Ann Intern Med 118:37-39, 1993
-
(1993)
Ann Intern Med
, vol.118
, pp. 37-39
-
-
Chattha, G.1
Arieff, A.I.2
Cummings, C.3
-
139
-
-
0025280828
-
Reye's syndrome in adult with AIDS
-
Jolliet P, Widmann JJ: Reye's syndrome in adult with AIDS [letter]. Lancet 335:1457, 1990
-
(1990)
Lancet
, vol.335
, pp. 1457
-
-
Jolliet, P.1
Widmann, J.J.2
-
141
-
-
0003232851
-
Four cases of fatal lactic acidosis due to mitochondrial toxicity of NRTI treatment: Analysis of clinical features and risk factors
-
San Francisco, CA
-
Ter Hofstede H, De Marie S, Foudraine N, et al: Four cases of fatal lactic acidosis due to mitochondrial toxicity of NRTI treatment: Analysis of clinical features and risk factors. In the 7th Conference on Retroviruses and Opportunistic Infections. San Francisco, CA, 2000
-
(2000)
7th Conference on Retroviruses and Opportunistic Infections
-
-
Ter Hofstede, H.1
De Marie, S.2
Foudraine, N.3
-
142
-
-
0033391005
-
A syndrome of peripheral fat wasting (lipodystrophy) in patients receiving long-term nucleoside analogue therapy
-
Saint-Marc T, Partisani M, Poizot-Martin I, et al: A syndrome of peripheral fat wasting (lipodystrophy) in patients receiving long-term nucleoside analogue therapy. AIDS 13:1659-1667, 1999
-
(1999)
AIDS
, vol.13
, pp. 1659-1667
-
-
Saint-Marc, T.1
Partisani, M.2
Poizot-Martin, I.3
-
143
-
-
0030711684
-
Cellular and molecular mechanisms of endothelial cell dysfunction
-
Harrison DG: Cellular and molecular mechanisms of endothelial cell dysfunction. J Clin Invest 100:2153-2157, 1997
-
(1997)
J Clin Invest
, vol.100
, pp. 2153-2157
-
-
Harrison, D.G.1
-
144
-
-
0036889521
-
Nucleoside reverse transcriptase inhibitors impair endothelium-dependent relaxation by increasing superoxide
-
Sutliff RL, Diakalov S, Parker J, et al: Nucleoside reverse transcriptase inhibitors impair endothelium-dependent relaxation by increasing superoxide. Am J Physiol Heart Circ Physiol 283:H2363-H2370, 2002
-
(2002)
Am J Physiol Heart Circ Physiol
, vol.283
-
-
Sutliff, R.L.1
Diakalov, S.2
Parker, J.3
-
146
-
-
0029037416
-
Combination antiretroviral therapy. Back to the future
-
Lange J: Combination antiretroviral therapy. Back to the future. Drugs 49:32-40, 1995
-
(1995)
Drugs
, vol.49
, pp. 32-40
-
-
Lange, J.1
-
147
-
-
0030708683
-
In search of a selective antiviral chemotherapy
-
De Clercq E: In search of a selective antiviral chemotherapy. Clin Microbiol Rev 10:674-693, 1997
-
(1997)
Clin Microbiol Rev
, vol.10
, pp. 674-693
-
-
De Clercq, E.1
-
148
-
-
0034966673
-
Antiviral drugs: Current state of the art
-
De Clercq E: Antiviral drugs: Current state of the art. J Clin Virol 22:73-89, 2001
-
(2001)
J Clin Virol
, vol.22
, pp. 73-89
-
-
De Clercq, E.1
|