The accessory subunit of Xenopus laevis mitochondrial DNA polymerase γ increases processivity of the catalytic subunit of human DNA polymerase γ and is related to class II aminoacyl-tRNA synthetases

Molecular and Cellular Biology

Volumn 19, Issue 6, 1999, Pages 4039-4046

  Carrodeguas, José A ^a   Kobayashi, Ryuji ^b   Lim, Susan E ^c   Copeland, William C ^c   Bogenhagen, Daniel F ^a  

^a STONY BROOK UNIVERSITY   (United States)

^b Howard Hughes Medical Institute Cold Spring Harbor Laboratory Cold Spring Harbor   (United States)

^c NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID TRANSFER RNA LIGASE; DNA DIRECTED DNA POLYMERASE GAMMA; MITOCHONDRIAL DNA; SIGNAL PEPTIDE;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; DNA SYNTHESIS; EVOLUTION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN TARGETING; XENOPUS LAEVIS;

EID: 0033010856     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/mcb.19.6.4039     Document Type: Article

References (34)

1. Bedford, E., S. Tabor, and C. C. Richardson. 1997. The thioredoxin binding domain of bacteriophage T7 DNA polymerase confers processivity on Escherichia coli DNA polymerase I. Proc. Natl. Acad. Sci. USA 94:479-484.
2. Bochkarev, A., R. A. Pfuetzner, A. M. Edwards, and L. Frappier. 1997. Structure of the single-stranded-DNA-binding domain of replication protein A bound to DNA. Nature 385:176-181.
3. Cermakian, N., T. M. Ikeda, R. Cedergren, and M. W. Gray. 1996. Sequences homologous to yeast mitochondrial and baeteriophage T3 and T7 RNA polymerases are widespread throughout the eukaryotic lineage. Nucleic Acids Res. 24:648-654.
4. Curth, U., C. Urbanke, J. Greipel, H. Gerberding, V. Tiranti, and M. Zeviani. 1994. Single-stranded-DNA-binding proteins from human mitochondria and Escherichia coli have analogous physicochemical properties. Eur. J. Biochem. 221:435-445.
5. Don, R. H., P. T. Cox, B. J. Wainwright, K. Baker, and J. S. Mattick. 1991. 'Touchdown' PCR to circumvent spurious priming during gene amplification. Nucleic Acids Res. 19:9007-9049.
6. Foury, F. 1989. Cloning and sequencing of the nuclear gene MIP 1 encoding the catalytic subunit of the yeast mitochondrial DNA polymerase. J. Biol. Chem. 264:20552-20560.
7. Fraser, T. H., and A. Rich. 1975. Amino acids are not all initially attached to the same position on transfer RNA molecules. Proc. Natl. Acad. Sci. USA 72:3044-3048.
8. Freist, W., D. T. Logan, and D. H. Gauss. 1996. Glycyl-tRNA synthetase. Biol. Chem. Hoppe-Seyler 377:343-356.
9. Ghrir, R., J. P. Lecaer, C. Dufresne, and M. Gueride. 1991. Primary structure of the two variants of Xenopus laevis mtSSB, a mitochondrial DNA binding protein. Arch. Biochem. Biophys. 291:395-400.
10. Graves, S. W., A. A. Johnson, and K. A. Johnson. 1998. Expression, purification, and initial kinetic characterization of the large subunit of the human mitochondrial DNA polymerase. Biochemistry 37:6050-6058.
11. Gray, H., and T. W. Wong. 1992. Purification and identification of subunit structure of the human mitochondrial DNA polymerase. J. Biol. Chem. 267:5835-5841.
12. Guan, M.-X. 1997. Cytoplasmic tyrosyl-tRNA synthetase rescues the defect in mitochondrial genome maintenance caused by the nuclear mutation mgm 104-1 in the yeast Saccharomyces cerevisiae. Mol. Gen. Genet. 255:525-532.
13. Harlow, E., and D. Lane. 1988. Antibodies: a laboratory manual. Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.
14. Hecht, S. M. 1979. Transfer RNA: structure, properties and recognition. Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.
15. Insdorf, N. F., and D. F. Bogenhagen. 1989. DNA polymerase gamma from Xenopus laevis. I. The identification of a high molecular weight catalytic subunit by a novel DNA polymerase photolabeling procedure. J. Biol. Chem. 264:21491-21497.
16. Lecrenier, N., P. Van Der Bruggen, and F. Foury. 1997. Mitochondrial DNA polymerases from yeast to man: a new family of polymerases. Gene 185:147-152.
17. Lewis, D. L., C. L. Farr, Y. Wang, A. T. Lagina, and L. S. Kaguni. 1996. Catalytic subunit of mitochondrial DNA polymerase from Drosophila embryos. Cloning, bacterial overexpression, and biochemical characterization. J. Biol. Chem. 271:23389-23394.
18. Logan, D. T., M. H. Mazauric, D. Kern, and D. Moras. 1995. Crystal structure of gtycyl-tRNA synthetase from Thermus thermophilus. EMBO J. 14: 4156-4167.
19. Longley, M. J., P. A. Ropp, S. E. Lim, and W. C. Copeland. 1998. Characterization of the native and recombinant catalytic subunit of human DNA polymerase γ: identification of residues critical for exonuclease activity and dideoxynucleotide sensitivity. Biochemistry 37:10529-10539.
20. Mahoungou, C., R. Ghrir, J. P. Lecaer, B. Mignotte, and M. Barat-Gueride. 1988. The amino-terminal sequence of the Xenopus laevis mitochondrial SSB is homologous to that of the Escherichia coli protein. FEBS Lett. 235:267-270.
21. Masters, B. S., L. L. Stohl, and D. A. Clayton. 1987. Yeast mitochondrial RNA polymerase is homologous to those encoded by bacteriophages T3 and T7. Cell 51:89-99.
22. Mazauric, M. H., G. Keith, D. Logan, R. Kreutzer, R. Giege, and D. Kern. 1998. Glycyl-tRNA synthetase from Thermus thermophilus - wide structural divergence with other prokaryotic glycyl-tRNA synthetases and functional inter-relation with prokaryotic and eukaryotic glycylation systems. Eur. J. Biochem. 251:744-757.
23. Mikhailov, V. S., and D. F. Bogenhagen. 1996. Effects of Xenopus laevis mitochondrial single-stranded DNA binding protein on primer-template binding and 3′→5′ exonuclease activity of DNA polymerase γ. J. Biol. Chem. 271:18939-18946.
24. Olson, M. W., Y. Wang, R. H. Elder, and L. S. Kaguni. 1995. Subunit structure of mitochondrial DNA polymerase from Drosophila embryos. Physical and immunological studies. J. Biol. Chem. 270:28932-28937.
25. Parisi, M. A., and D. A. Clayton. 1991. Similarity of human mitochondrial transcription factor 1 to high mobility group proteins. Science 252:965-969.
26. Ropp, P. A., and W. C. Copeland. 1995. Characterization of a new DNA polymerase from Schizosaccharomyces pombe: a probable homologue of the Saccharomyces cerevisiae DNA polymerase gamma. Gene 165:103-107.
27. Ropp, P. A., and W. C. Copeland. 1996. Cloning and characterization of the human mitochondrial DNA polymerase, DNA polymerase γ. Genomics 36: 449-458.
28. Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular cloning: a laboratory manual, 2nd ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
29. Sprinzl, M., and F. Cramer. 1975. Site of aminoacylation of tRNAs from Escherichia coli with respect to the 2′- or 3′-hydroxyl group of the terminal adenosine. Proc. Natl. Acad. Sci. USA 72:3049-3053.
30. Tabor, S., H. E. Huber, and C. C. Richardson. 1987. Escherichia coli thioredoxin confers processivity on the DNA polymerase activity of the gene 5 protein of bacteriophage T7. J. Biol. Chem. 262:16212-16223.
31. Van Dyck, E., F. Foury, B. Stillman, and S. J. Brill. 1992. A single-stranded DNA binding protein required for mitochondrial DNA replication in S. cerevisiae is homologous to E. coli SSB. EMBO J. 11:3421-3430.
32. Wang, R., R. Kobayashi, and J. Bishop. 1996. Cellular adherence elicits ligand-independent activation of the Met cell-surface receptor. Proc. Natl. Acad. Sci. USA 93:8425-8430.
33. Wang, Y., C. L. Farr, and L. S. Kaguni. 1997. Accessory subunit of mitochondrial DNA polymerase from Drosophila embryos. J. Biol. Chem. 272: 13640-13646.
34. Ye, F., J. A. Carrodeguas, and D. F. Bogenhagen. 1996. The γ subfamily of DNA polymerases: cloning of a developmentally regulated cDNA encoding Xenopus laevis mitochondrial DNA polymerase γ. Nucleic Acids Res. 24: 1481-1488.