Differential Incorporation and Removal of Antiviral Deoxynucleotides by Human DNA Polymerase γ

Journal of Biological Chemistry

Volumn 276, Issue 26, 2001, Pages 23616-23623

  Lim, Susan E ^b   Copeland, William C ^a  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

BIOSYNTHESIS; CELLS; DNA; ENZYMES; IMMUNOLOGY; TOXICITY;

NUCLEOTIDES;

BIOCHEMISTRY;

2',3' DIDEOXYCYTIDINE 5' TRIPHOSPHATE; ABACAVIR; ANTIRETROVIRUS AGENT; ANTIVIRUS AGENT; CARBOVIR; DIDANOSINE; DNA DIRECTED DNA POLYMERASE GAMMA; LAMIVUDINE; MITOCHONDRIAL DNA; NUCLEOSIDE ANALOG; STAVUDINE; ZALCITABINE; ZIDOVUDINE; 3'-AZIDO-3'-DEOXYTHYMIDINE 5'-TRIPHOSPHATE; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; CARBOVIR TRIPHOSPHATE; CYTIDINE TRIPHOSPHATE; DEOXYGUANOSINE PHOSPHATE; DEOXYRIBONUCLEOTIDE; DNA; DNA DIRECTED DNA POLYMERASE; DRUG DERIVATIVE; EXODEOXYRIBONUCLEASE; LAMIVUDINE TRIPHOSPHATE; PYRIMIDINE NUCLEOTIDE; RNA DIRECTED DNA POLYMERASE INHIBITOR; ZIDOVUDINE 5' TRIPHOSPHATE;

ARTICLE; DNA SYNTHESIS INHIBITION; DRUG MECHANISM; DRUG STRUCTURE; ENZYME ASSAY; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MITOCHONDRION; MYOPATHY; NONHUMAN; PERIPHERAL NEUROPATHY; PRIORITY JOURNAL; BIOSYNTHESIS; DNA REPLICATION; DRUG ANTAGONISM; DRUG EFFECT; ENZYME SPECIFICITY; KINETICS; METABOLISM;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; INSERTION SEQUENCES;

ANTI-HIV AGENTS; CYTIDINE TRIPHOSPHATE; DEOXYGUANINE NUCLEOTIDES; DEOXYRIBONUCLEOTIDES; DNA; DNA REPLICATION; DNA-DIRECTED DNA POLYMERASE; EXODEOXYRIBONUCLEASES; HUMANS; KINETICS; LAMIVUDINE; REVERSE TRANSCRIPTASE INHIBITORS; STAVUDINE; SUBSTRATE SPECIFICITY; THYMINE NUCLEOTIDES; ZALCITABINE; ZIDOVUDINE;

EID: 0035968164     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M101114200     Document Type: Article

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