AZT treatment induces molecular and ultrastructural oxidative damage to muscle mitochondria. Prevention by antioxidant vitamins

Journal of Clinical Investigation

Volumn 102, Issue 1, 1998, Pages 4-9

  García De La Asunción, José ^a,b   Del Olmo, Maria L ^a   Sastre, Juan ^a   Millán, Arantxa ^a   Pellín, Antonio ^a   Pallardó, Federico V ^a  

^a UNIVERSITY OF VALENCIA   (Spain)

^b UNIVERSITY OF VALENCIA   (Spain)

Author keywords

8 Dihydro 2' deoxyguanosine; Antioxidant vitamins; AZT; Mitochondrial DNA damage; Oxidative damage

Indexed keywords

ANTIOXIDANT; ISATORIBINE; ZIDOVUDINE;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL DAMAGE; CELL ULTRASTRUCTURE; CONTROLLED STUDY; DNA DAMAGE; DRUG EFFECT; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LIPID PEROXIDATION; MITOCHONDRIAL MYOPATHY; MOUSE; MUSCLE MITOCHONDRION; NONHUMAN; ORAL DRUG ADMINISTRATION; OXIDATIVE STRESS; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; VIRUS REPLICATION;

EID: 1842570096     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/jci1418     Document Type: Article

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