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Volumn 277, Issue 21, 2002, Pages 18411-18420
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Kaurane diterpene, kamebakaurin, inhibits NF-κB by directly targeting the DNA-binding activity of p50 and blocks the expression of antiapoptotic NF-κB target genes
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Author keywords
[No Author keywords available]
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Indexed keywords
CELLS;
ENZYME INHIBITION;
MASS SPECTROMETRY;
MUTAGENESIS;
PLANTS (BOTANY);
TUMORS;
APOPTOSIS;
BIOCHEMISTRY;
CELL DNA;
CYSTEINE;
GENE PRODUCT;
I KAPPA B;
IMMUNOGLOBULIN ENHANCER BINDING PROTEIN;
KAURENE DERIVATIVE;
KEMEBAKAURIN;
MUTANT PROTEIN;
PROTEIN BCL 2;
PROTEIN P50;
TUMOR NECROSIS FACTOR ALPHA;
UNCLASSIFIED DRUG;
APOPTOSIS;
ARTICLE;
CANCER;
CELL STRAIN MCF 7;
CELL TYPE;
CONTROLLED STUDY;
COVALENT BOND;
DNA BINDING;
DRUG EFFECT;
DRUG MECHANISM;
DRUG PROTEIN BINDING;
DRUG STRUCTURE;
DRUG TARGETING;
GENE ACTIVATION;
GENE TARGETING;
GENETIC CODE;
HUMAN;
HUMAN CELL;
IMMUNE RESPONSE;
IN VITRO STUDY;
INFLAMMATION;
INTRACELLULAR TRANSPORT;
MASS SPECTROMETRY;
MULTIGENE FAMILY;
PRIORITY JOURNAL;
PROTEIN DEGRADATION;
STRUCTURE ACTIVITY RELATION;
DITERPENES;
DNA;
HUMANS;
JURKAT CELLS;
LIPOPOLYSACCHARIDES;
NF-KAPPA B;
TETRADECANOYLPHORBOL ACETATE;
TUMOR NECROSIS FACTOR-ALPHA;
MINK CELL FOCUS-FORMING VIRUS;
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EID: 0037166268
PISSN: 00219258
EISSN: None
Source Type: Journal
DOI: 10.1074/jbc.M201368200 Document Type: Article |
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Times cited : (146)
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References (44)
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