Nuclear receptor coactivator ACTR is a novel histone acetyltransferase and forms a multimeric activation complex with P/CAF and CBP/p300

Cell

Volumn 90, Issue 3, 1997, Pages 569-580

  Chen, Hongwu ^e   Lin, Richard J ^a,b   Schiltz, R Louis ^c   Chakravarti, Debabrata ^a   Nash, Alyssa ^a   Nagy, Laszlo ^a   Privalsky, Martin L ^d   Nakatani, Yoshihiro ^c   Evans, Ronald M ^a  

^a SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e NONE

Author keywords

[No Author keywords available]

Indexed keywords

ACYLTRANSFERASE; CELL NUCLEUS RECEPTOR;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; DIMERIZATION; ENZYME ACTIVATION; ENZYME ACTIVITY; LIGAND BINDING; NONHUMAN; PRIORITY JOURNAL; PROTEIN FAMILY; TRANSACTIVATION;

ANIMALIA;

EID: 0030740253     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(00)80516-4     Document Type: Article

References (59)

1. Arany, Z., Sellers,W.R., Livingston, D.M., and Eckner, R. (1994). E1A-associated p300 and CREB-associated CBP belong to a conserved family of coactivators. Cell 77, 799-800.
2. Arias, J., Alberts, A.S., Brindle, P., Claret, F.X., Smeal, T., Karin, M., Feramisco, J., and Montminy, M. (1994). Activation of cAMP and mitogen responsivegenes relieson acommon nuclear factor. Nature 370, 226-229.
3. Baniahmad, A., Ha, I., Reinberg, D.,Tsai, S., Tsai, M.J., and O'Malley, B.W. (1993). Interaction of human thyroid hormone receptor beta with transcription factor TFIIB may mediate target gene derepression and activation by thyroid hormone. Proc. Natl. Acad. Sci. USA 90, 8832-8836.
4. Baniahmad, A., Leng, X., Burris, T.P., Tsai, S.Y., Tsai, M.J., and O'Malley, B.W. (1995). The Tau-4 activation domain of the thyroid hormone receptoris required for release of a putative corepressor(s) necessary for transcriptional silencing. Mol. Cell. Biol. 15, 76-86.
5. Bannister, A.J., and Kouzarides, T. (1995). CBP-induced stimulation of c-fos activity is abrogated by E1A. EMBO J. 14 , 4758-4762.
6. Bannister, A.J., and Kouzarides, T. (1996). The CBP coactivator is a histone acetyltransferase. Nature 384, 641-643.
7. Barettino, D., Vivanco Ruiz, M.M., and Stunnenberg, H.G. (1994). Characterization of the ligand-dependent transactivation domain of thyroid hormone receptor. EMBO J. 13, 3039-3049.
8. Bartsch, J., Truss, M., Bode, J., and Beato, M. (1996). Moderate increase in histone acetylation activates the mouse mammary tumor virus promoter and remodels its nucleosome structure. Proc. Natl. Acad. Sci. USA 93, 10741-10746.
9. Bhattacharya, S., Eckner, R., Grossman, S., Oldread, E., Arany, Z., D'Andrea, A., and Livingston, D.M. (1996). Cooperation of Stat2 and p300/CBP in signaling induced by interferon-alpha. Nature 383, 344-347.
10. Blanco, J.C.G., Wang, I.-M., Tsai, S.Y., Tsai, M.J., O'Malley, B.W., Jurutka, P.W., Haussler, M.R., and Ozato, K. (1995). Transcription factor TFIIB and the vitamin D receptor cooperatively activate ligand-dependent transcription. Proc. Natl. Acad. Sci. USA 92, 1535-1539.
11. Brownell, J.E., and Allis, C.D. (1996). Special HATs for special occasions: linking histone acetylation to chromatin assembly and gene activation. Curr. Opin. Genet. Dev. 6, 176-184.
12. Chakravarti, D., LaMorte, V.J., Nelson, M.C., Nakajima, T., Juguilon, H., Montminy, M., and Evans, R.M. (1996). Role of CBP/p300 in nuclear receptor signaling. Nature 383, 99-103.
13. Chen, J.D., and Evans, R.M. (1995). A transcriptional corepressor that interacts with nuclear hormone receptors. Nature 377, 454-457.
14. Chen, H., Smit-McBride, Z., Lewis, S., Sharif, M., and Privalsky, M.L. (1993). Nuclear hormone receptors involved in neoplasia: ErbA exhibits a novel DNA sequence specificity determined by amino acids outside of the zinc-finger domains. Mol. Cell. Biol. 13, 2366-2376.
15. Chrivia, J.C., Kwok, R.P.S., Lamb, N., Hagiwara, M., Montminy, M.R., and Goodman, R.H. (1993). Phosphorylated CREB binds specifically to the nuclear protein CBP. Nature 365, 855-859.
16. Durand, B., Sanders, M., Gaudon, C., Roy, B., Losson, R., and Chambon, P. (1994). Activation function 2 (AF-2)of retinoic acid receptor and 9-c/s retinoic acid receptor: presence of a conserved autonomous constitutive activating domain and influence of the nature of the response element on AF-2 activity. EMBO J. 13, 5370-5382.
17. Eckner, R., Yao, T.-P., Oldread, E., and Livingston, D.M. (1996). Interaction and functional collaboration of p300/CBP and bHLH proteins in muscle and B-cell differentiation. Genes Dev. 70, 2478-2490.
18. Fragoso, G., John, S., Roberts, M.S., and Hager, G.L. (1995). Nucleosome positioning on the MMTV LTR results from the frequency biased occupancy of multiple frames. Genes Dev. 9, 1933-1947.
19. Fondell, J.D., Roy, A.L., and Roeder, R.G. (1993). Unliganded thyroid hormone receptor inhibits formation of a functional preinitiation complex: implication for active repression. Genes Dev. 7, 1400-1410.
20. Fondell, J.D., Ge, H., and Roeder, R.G. (1996). Ligand induction of a transcriptionally active thyroid hormone receptor coactivator complex. Proc. Natl. Acad. Sci. USA 93, 8329-8333.
21. Glass, C.K. (1994). Differential recognition of target genes by nuclear receptor monomers, dimers, and heterodimers. Endocrine Reviews 15, 391-407.
22. Gstaiger, M., Knoepfel, L., Georgiev, O., Schaffner, W., and Hovens, C.M. (1995). A B-cell coactivator of octamer-binding transcription factors. Nature 373, 360-362.
23. Hankinson, O. (1995). The aryl hydrocarbon receptor complex. Annu. Rev. Pharmacol. Toxicol. 35, 307-340.
24. Hanstein, B., Eckner, R., DiRenzo, J., Halachmi, S., Liu, H., Searcy, B., and Brown, M. (1996). p300 is a component of an estrogen receptor coactivator complex. Proc. Natl. Acad. Sci. USA 93, 11540-11545.
25. Hayes, J.J., Pruss, D., and Wolffe, A.P. (1994). Contacts of the globular domain of histone H5 and core histones with DN Aina"chromatosome." Proc. Natl. Acad. Sci. USA 91, 7817-7821.
26. Heinzel, T., Lavinsky, R.M., Mullen, T.-M., Soderstrom, M., Laherty, C.D., Torchia, J., Yang, W.-M., Brard, G., Ngo, S.D., Davie, J.R., et al. (1997). A complex containing N-CoR, mSin3 and histone deacetylase mediates transcriptional repression. Nature 387, 43-48.
27. Hong, H., Kohli, K., Trivedi, A., Johnson, D.L., and Stallcup, M.R. (1996). GRIP1, a novel mouse protein that serves as atranscriptional coactivator in yeast for the hormone binding domains of steroid receptors. Proc. Natl. Acad. Sci. USA 93, 4948-952.
28. Horlein, A.J., Naar, A.M., Heinzel, T., Torchia, J., Gloss, B., Kurokawa, R., Ryan, A., Kamei, Y., Soderstrom, M., Glass, C.K., and Rosenfeld, M.G. (1995). Ligand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor corepressor. Nature 377, 397-404.
29. Horwitz, K.B., Jackson, T.A., Bain, D.L., Richer, J.K., Takimoto, G.S., and Tung, L. (1996). Nuclear receptor coactivators and corepressors. Mol. Endocrinol. 10, 1167-1177.
30. Ing, N.H., Beekman, J.M., Tsai, S.Y., Tsai, M.J., and O'Malley, B.W. (1992). Members of the steroid hormone receptor superfamily inter-act with TFIIB (S300-II). J. Biol. Chem. 267, 17617-17623.
31. Janknecht, R., and Hunter, T. (1996). Transcription control: versatile molecular glue. Curr. Biol. 6, 951-954.
32. Kamei, Y., Xu, L., Heinzel, T., Torchia, J., Kurokawa, R., Gloss, B., Lin, S.-C., Heyman, R.A., Rose, D.W., Glass, C.K., and Rosenfeld, M.G. (1996). ACBPintegrator complex mediates transcriptional activation and AP-1 inhibition by nuclear receptors. Cell 85, 403-414.
33. Kuo, M.-H., Brownell, J.E., Soebel, R.E., Ranalli, T.A., Cook, R.G., Edmondson, D.G., Roth, S.Y., and Allis, C.D. (1996). Transcription-linked acetylation by Gcn5p of histones H3 and H4 at specific lysines. Nature 383, 269-272.
34. Kwok, R.P.S., Lundland, J.R., Chrivia, J.C., Richards, J.P., Bachinger, H.P., Brennan, R.G., Roberts, S.G.E., Green, M.R., and Goodman, R.H. (1994). Nuclear protein CBP is a coactivator for the transcription factor CREB. Nature 370, 223-226.
35. Lala, D.S., Mukherjee, R., Schulman, I.G., Canan-Koch, S.S., Dardashti, L.J., Nadzan, A.M., Croston, G.E., Evans, R.M., and Heyman, R.A. (1996). Activation of specific RXR heterodimers by an antagonist of RXR homodimers. Nature 383, 450-453.
36. Le Douarin, B., Nielsen, A.L., Gamier, J.-M., Ichinose, H., Jeanmougin, F., Losson, R., and Chambon, P. (1996). A possible involvement of TIF1-alpha and TIF1-beta in the epigenetic control of transcription by nuclear receptors. EMBO J. 15, 6701-6715.
37. Leng, X., Blanco, J., Tsai, S.Y., Ozato, K., O'Malley, B.W., and Tsai, M.J. (1995). Mouse retinoid X receptor contains a separable ligand-binding and transactivation domain in its E region. Mol. Cell. Biol. 15, 255-263.
38. Mangelsdorf, D.J., and Evans, R.M. (1995). The RXR heterodimers and orphan receptors. Cell 83, 841-850.
39. Mangelsdorf, D.J., Thummel, C., Beato, M., Herrlich, P., Schutz, G., Umesono, K., Kastner, P., Mark, M., Chambon, P., and Evans, R.M. (1995). The nuclear receptor superfamily: the second decade. Cell 83, 835-839.
40. Meyer, M.-E., Gronemeyer, H., Turcotte, B., Bocquel, M.-T., Tasset, D., and Chambon, P. (1989). Steroid receptors compete for factors that mediate their enhancer function. Cell 57, 433-442.
41. II 250 subunit of TFIID has histone acetyltransferase activity. Cell 87, 1261-1270.
42. Nagy, L., Kao, H.-Y., Chakravarti, D., Lin, R.J., Hassig, C.A., Ayer, D.E., Schreiber, S.L., and Evans, R.M. (1997). Nuclear receptor repression mediated by a complex containing SMRT, mSin3A, and histone deacetylase. Cell 89, 373-380.
43. Ogryzko, V.V., Schiltz, R.L., Russanova, V., Howard, B.H., and Nakatani, Y. (1996). The transcription coactivators p300 and CBP are histone acetyltransferase. Cell 87, 953-959.
44. Onate, S.A., Tsai, S.Y., Tsai, M.J., and O'Malley, B.M. (1995). Sequence and characterization of a coactivator for the steroid hormone receptor superfamily. Science 270, 1354-1357.
45. Pazin, M.J., and Kadonaga, J.T. (1997). What's up and down with histone deacetylation and transcription? Cell 89, 325-328.
46. Perkins, N.D., Felzien, L.K., Betts, J.C., Leung, K., Beach, D.H., and Nabel, G.J. (1997). Regulation of NF-kappa B by cyclin-dependent kinase associated with the p300 coactivator. Science 275, 523-527.
47. Sande, S., and Privalsky, M.L. (1996). Identification of TRACs, a family of cofactors that associate with, and modulate the activity of nuclear hormone receptors. Mol. Endocrinol. 10, 813-825.
48. Schulman, I.G., Chakravarti, D., Juguilon, H., Romo, A., and Evans, R.M. (1995). Interactions between the retinoid Xreceptor and a conserved region of the TATA-binding protein mediate hormone-dependent transactivation. Proc. Natl. Acad. Sci. USA. 92, 8288-8292.
49. Schulman, I.G., Juguilon, H., and Evans, R.M. (1996). Activation and repression by nuclear hormone receptors: hormone modulates an equilibrium between active and repressive states. Mol. Cell. Biol. 16, 3807-3813.
50. Soel, W., Choi, W.S., and Moore, D.D. (1995). Isolation of proteins that interact specifically with the retinoid X receptor: two novel orphan receptors. Mol. Endocrinol. 9, 72-85.
51. Truss, M., Bartsch, J., Schelbert, A., Hache, R.J.G., and Beato, M. (1995). Hormone induces binding of receptors and transcription factors to a rearranged nucleosome on the MMTV promoter in vivo. EMBO J. 14, 1737-1751.
52. Voegel, J.J., Heine, M.J.S., Zechel, C., Chambon, P., and Gronemeyer, H. (1996). TIF2, a 160 kDa transcriptional mediator for the ligand-dependent activation function AF-2 of nuclear receptors. EMBO J. 15, 3667-3675.
53. Wolffe, A.P. (1997). Sinful repression. Nature 387, 16-17.
54. Wolffe, A.P., and Pruss, D. (1996). Targeting chromatin disruption: transcription regulators that acetylate histones. Cell 84, 817-819.
55. Wong, J., Shi, Y.-B., and Wolffe, A.P. (1995). A role for nucleosome assembly in both silencing and activation of the Xenopus TRβA gene by the thyroid hormone receptor. Genes Dev. 9, 2696-2711.
56. Yang, X.-J., Ogryzko, V.V., Nishikawa, J., Howard, B.H., and Nakatani, Y. (1996). A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A. Nature 382, 319-324.
57. Yao, T.-P., Ku, G., Zhou, N., Scully, R., and Livingston, D.M. (1996). The nuclear hormone receptor coactivator SRC-1 is a specific target of p300. Proc. Natl. Acad. Sci. USA 93, 10626-10631.
58. Zaret, K.S., and Yamamoto, K.R. (1984). Reversible and persistent changes in chromatin structure accompany activation of a glucocorticoid dependent enhancer element. Cell 38, 29-38.
59. Zhang, J.J., Vinkemeier, U., Gu, W., Chakravarti, D., Horvath, C.M., and Darnell, J.E. (1996). Two contact regions between Stal1 and CBP/p300in interferon gamma signaling. Proc. Natl. Acad. Sci. USA 93, 15092-15096.