Notch signaling promotes astrogliogenesis via direct CSL-mediated glial gene activation

Journal of Neuroscience Research

Volumn 69, Issue 6, 2002, Pages 848-860

  Ge, Weihong ^a   Martinowich, Keri ^a   Wu, Xiangbing ^a   He, Fei ^a   Miyamoto, Alison ^a   Fan, Guoping ^a   Weinmaster, Gerry ^a   Sun, Yi Eve ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Astrocytes; CSL proteins; Delta; Neural stem cells; Notch

Indexed keywords

DNA BINDING PROTEIN; GLIAL FIBRILLARY ACIDIC PROTEIN; NOTCH RECEPTOR; PROTEIN; PROTEIN CSL; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; ASTROCYTE; GENE ACTIVATION; GENE TARGETING; GLIA CELL; MACROGLIA; NERVE CELL DIFFERENTIATION; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION;

ANIMALS; ASTROCYTES; CELL DIFFERENTIATION; CELLS, CULTURED; CEREBRAL CORTEX; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GLIAL FIBRILLARY ACIDIC PROTEIN; JANUS KINASE 1; MEMBRANE PROTEINS; MICE; MUTAGENESIS; PROMOTER REGIONS (GENETICS); PROTEIN-TYROSINE KINASES; RATS; RATS, LONG-EVANS; RECEPTORS, NOTCH; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; STEM CELLS; TRANS-ACTIVATION (GENETICS); TRANS-ACTIVATORS;

EID: 0037106147     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/jnr.10364     Document Type: Article

References (59)

1. Notch signaling
2. Notch signaling: Cell fate control and signal integration in development
3. The origin of the ankyrin repeat region in Notch intracellular domains is critical for regulation of HES promoter activity
4. Intracellular cleavage of Notch leads to a heterodimeric receptor on the plasma membrane
5. Regulation of gliogenesis in the central nervous system by the JAK-STAT signaling pathway
6. The abruptex mutations of notch disrupt the establishment of proneural clusters in Drosophila
7. Inhibition of the DNA-binding activity of Drosophila suppressor of hairless and of its human homolog, KBF2/RBP-Jkappa, by direct protein-protein interaction with Drosopila hairless
8. A novel proteolytic cleavage involved in Notch signaling: The role of the disintegrin-metalloprotease TACE
9. Analysis of neuronal and glial phenotypes in brains of mice deficient in leukemia inhibitory factor
10. Ligand-induced signaling in the absence of furin processing of Notch1
11. Spatiotemporal selectivity of response to Notch1 signals in mammalian forebrain precursors
12. lag-1. A gene required for lin-12 and glp-1 signaling in Caenorhabditis elegans, is homologous to human CBF1 and Drosophila Su(H)
13. Conservation of the Notch signaling pathway in mammalian neurogenesis
14. A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain
15. Rax, Hes1, and notch1 promote the formation of Muller glia by postnatal retinal progenitor cells
16. Radial glial identity is promoted by Notch1 signaling in the murine forebrain
17. Cell interactions and gene interactions in peripheral neurogenesis
18. Single factors direct the differentiation of stem cells from the fetal and adult central nervous system
19. Helix-loop-helix factors in growth and differentiation of the vertebrate nervous system
20. Neural precursor differentiation into astrocytes requires signaling through the leukemia inhibitory factor receptor
21. The Notch pathway: Democracy and aristocracy in the selection of cell fate
22. A subset of notch functions during Drosophila eye development require Su(H) and the E(spl) gene complex
23. The Notch1 receptor is cleaved constitutively by a furin-like convertase
24. Neurogenin1 is essential for the determination of neuronal precursors for proximal cranial sensory ganglia
25. Transient Notch activation initiates an irreversible switch from neurogenesis to gliogenesis by neural crest stem cells
26. Developmental requirement of gp130 signaling in neuronal survival and astrocyte differentiation
27. Synergistic signaling in fetal brain by STAT3-Smad1 complex bridged by p300
28. Neural bHLH genes control the neuronal versus glial fate decision in cortical progenitors
29. Neurons derived from radial glial cells establish radial units in neocortex
30. Notch signaling imposes two distinct blocks in the differentiation of C2C12 myoblasts
31. Coordinate regulation of motor neuron subtype identity and pan-neuronal properties by the bHLH repressor Olig2
32. Hesl and Hes5 as notch effectors in mammalian neuronal differentiation
33. Disruption of the mouse RBP-Jkappa gene results in early embryonic death
34. Development of neuronal precursor cells and functional postmitotic neurons from embryonic stem cells in vitro
35. Notch inhibition of E47 supports the existence of a novel signaling pathway
36. p300 acts as a transcriptional coactivator for mammalian Notch-1
37. Timing of CNS cell generation: A programmed sequence of neuron and glial cell production from isolated murine cortical stem cells
38. Novel Notch alleles reveal a Deltex-dependent pathway repressing neural fate
39. Calcium depletion dissociates and activates heterodimeric notch receptors
40. Nuclear Notch1 signaling and the regulation of dendritic development
41. The basic helix-loop-helix gene hesr2 promotes gliogenesis in mouse retina
42. Contact-dependent inhibition of cortical neurite growth mediated by notch signaling
43. Notch signaling inhibits muscle cell differentiation through a CBF1-independent pathway
44. Proteolytic release and nuclear translocation of Notch-1 are induced by presenilin-1 and impaired by pathogenic presenilin-1 mutations
45. Presenilin is required for activity and nuclear access of Notch in Drosohila
46. Neurogenin promotes neurogenesis and inhibits glial differentiation by independent mechanisms
47. DNA methylation is a critical cell-intrinsic determinant of astrocyte differentiation in the fetal brain
48. Notch1 and Notch3 instructively restrict bFGF-responsive multipotent neural progenitor cells to an astroglial fate
49. Direct neural fate specification from embryonic stem cells: A primitive mammalian neural stem cell stage acquired through a default mechanisms
50. Notch receptor activation inhibits oligodendrocyte differentiation
51. The ins and outs of notch signaling
52. MAML1, a human homologue of Drosophila mastermind, is a transcriptional co-activator for Notch receptors
53. Role of Deltex-1 as a transcriptional regulator downstream of the Notch receptor
54. Neurogenic phenotypes and altered Notch processing in Drosophila presenilin mutants
55. Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and betaAPP processing
56. An activity of Notch regulates JNK signaling and affects dorsal closure in Drosophila
57. The bHLH transcription factor Olig2 promotes oligodendrocyte differentiation in collaboration with Nkx2.2
58. SKIP, a CBF1-associated protein, interacts with the ankyrin repeat domain of Notch 1C to facilitate Notch 1C function