TrkB Gene Transfer Protects Retinal Ganglion Cells from Axotomy-Induced Death in Vivo

Journal of Neuroscience

Volumn 22, Issue 10, 2002, Pages 3977-3986

  Cheng, Li ^a   Sapieha, Przemyslaw ^a   Kittlerová, Pavia ^b   Hauswirth, William W ^c   Di Polo, Adriana ^a  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

^b MONTREAL GENERAL HOSPITAL   (Canada)

^c UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

Author keywords

Axotomy; Cell survival; Gene transfer; MAP kinase; Retinal ganglion cells; TrkB

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; BRAIN DERIVED NEUROTROPHIC FACTOR RECEPTOR; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTECTIVE AGENT; ENZYME INHIBITOR; ONCOPROTEIN; PROTEIN KINASE B; PROTEIN SERINE THREONINE KINASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL DEATH; CELL LEVEL; CELL PROTECTION; CELL SURVIVAL; CONTROLLED STUDY; DISEASE MODEL; ENZYME ACTIVATION; FEMALE; GENE TRANSFER; IN VIVO STUDY; NERVE FIBER TRANSECTION; NONHUMAN; OPTIC NERVE INJURY; PRIORITY JOURNAL; RAT; RETINA GANGLION CELL; ADENO ASSOCIATED VIRUS; ANIMAL; CYTOLOGY; DOWN REGULATION; DRUG EFFECT; GENE VECTOR; GENETICS; HORIZONTAL GENE TRANSFER; METABOLISM; PHYSIOLOGY; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT; UPREGULATION;

ANIMALS; AXOTOMY; CELL DEATH; CELL SURVIVAL; CYTOPROTECTION; DEPENDOVIRUS; DOWN-REGULATION; ENZYME ACTIVATION; ENZYME INHIBITORS; FEMALE; GENE TRANSFER, HORIZONTAL; GENETIC VECTORS; MITOGEN-ACTIVATED PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, TRKB; RETINAL GANGLION CELLS; RNA, MESSENGER; SIGNAL TRANSDUCTION; UP-REGULATION;

EID: 0037095710     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.22-10-03977.2002     Document Type: Article

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