Reporter expression persists 1 year after adeno-associated virus- mediated gene transfer to the optic nerve

Archives of Ophthalmology

Volumn 117, Issue 7, 1999, Pages 929-937

  Guy, John ^a   Qi, Xiaoping ^a   Muzyczka, Nicholas ^a   Hauswirth, William W ^a  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA GALACTOSIDASE; CATALASE; GREEN FLUORESCENT PROTEIN;

ADENOVIRUS; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; GENE TRANSFER; GUINEA PIG; HISTOPATHOLOGY; IMMEDIATE EARLY GENE; IMMUNOHISTOCHEMISTRY; NONHUMAN; OPTIC NERVE ATROPHY; OPTIC NERVE DISEASE; PRIORITY JOURNAL; PROMOTER REGION; REPORTER GENE;

EID: 0032788451     PISSN: 00039950     EISSN: None     Source Type: Journal    
DOI: 10.1001/archopht.117.7.929     Document Type: Article

References (36)

1. Ruuls SR, Bauer J, Sontrop K, Huitinga I, Hart BA, Dijkstra CD. Reactive oxygen species are involved in the pathogenesis of experimental allergic encephalomyelitis in Lewis rats. J Neuroimmunol. 1995;56:207-217.
2. Brett R, Rumsby MG. Evidence of free radical damage in the central nervous system of guinea pigs at the prolonged acute and early stages of chronic relapsing experimental allergic encephalomyelitis. Neurochem Int. 1993;23: 35-44.
3. Guy J, Ellis EA, Mames R, Rao NA. Role of hydrogen peroxide in experimental optic neuritis: a serial quantitative ultrastructural study. Ophthalmic Res. 1993; 25:253-264.
4. 2 and extravasated serum albumin. Invest Ophthalmol Vis Sci. 1994;35:1114-1123.
5. Guy JR, Ellis EA, Hope GM, Rao NA. Influence of antioxidant enzymes in reduction of optic disc edema in experimental optic neuritis. Free Radic Biol Med. 1986; 2:349-357.
6. Guy J, McGorray S, Fitzsimmons J, et al. Reversals of BBB disruption by catalase: a serial MRI study of experimental optic neuritis. Invest Ophthalmol Vis Sci. 1994;35:3456-3465.
7. Alford EC Jr, Kies MW, Suckling AJ. Experimental Allergic Encephalomyelitis: A Useful Model for Multiple Sclerosis. New York, NY: Alan R Liss Inc 1984.
8. Kim YS, Kim SU. Oligodendroglial cell death induced by oxygen radicals and its protection by catalase. J Neurosci Res. 1991;29:100-106.
9. Rao NA. Chronic experimental allergic optic neuritis. Invest Ophthalmol Vis Sci. 1981;20:159-172.
10. Guy J, Rao NA. Acute and chronic experimental optic neuritis: alteration in the blood-optic nerve barrier. Arch Ophthalmol. 1984;102:450-454.
11. Greenwald RA. Superoxide dismutase and catalase as therapeutic agents for human diseases: a critical review. Free Radic Biol Med. 1990;8:201-209.
12. Flannery JG, Zolotukhin S, Vaquero MI, LaVail MM, Muzyczka N, Hauswirth WW. Efficient photoreceptor-targeted gene expression in vivo by recombinant adeno-associated virus. Proc Natl Acad Sci U S A. 1997;94:6916-6921.
13. Bennett J, Wilson J, Sun D, Forbes B. Maguire A. Adenovirus vector-mediated in vivo gene transfer into adult murine retina. Invest Ophthalmol Vis Sci. 1994;35: 2535-2542.
14. Li T, Adamian M, Roof DJ, et al. In vivo transfer of a reporter gene to the retina mediated by an adenoviral vector. Invest Ophthalmol Vis Sci. 1994;35:2543-2549.
15. Zolotukhin S, Potter M, Hauswirth W, Guy J, Muzyczka N. A "humanized" green fluorescent protein cDNA adapted for high level expression in mammalian cells. J Virol. 1996;70:4646-4654.
16. Mashhour B, Couton D, Perricaudet M, Briand P. In vivo adenovirus-mediated gene transfer into ocular tissues. Gene Ther. 1994;1:122-126.
17. Bennett J, Tanabe T, Sun D, et al. Photoreceptor cell rescue in retinal degeneration (rd) mice by in vivo gene therapy. Nat Med. 1996;2:649-654.
18. Ali RR, Reichel MB, Thrasher AJ, et al. Gene transfer into the mouse retina mediated by an adeno-associated viral vector. Hum Mol Genet. 1996;5:591-594.
19. Akli S, Caillaud C. Vigne E, et al. Transfer of a foreign gene into the brain using adenovirus vectors. Nat Genet. 1993;3:224-228.
20. Peel AL, Zolotukhin S, Schrimsher GW, Muzyczka N, Rier PJ. Efficient transduction of green fluorescent protein in spinal cord neurons using adeno-associated virus vectors containing cell type-specific promoters. Gene Ther. 1997;4:16-24.
21. Erzurum SC, Lemarchand P, Rosenfeld MA, Yoo J-H, Crystal RG. Protection of human endothelial cells from oxidant injury by adenovirus-mediated transfer of the human catalase cDNA. Nucleic Acids Res. 1993;21:1607-1612.
22. Cayouette M, Gravel C. Adenovirus-mediated gene transfer to retinal ganglion cells. Invest Ophthalmol Vis Sci. 1996;37:2022-2028.
23. Lem J, Applebury ML, Falk JD, Flannery JG, Simon MI. Tissue-specific and developmental regulation of rod opsin chimeric genes in transgenic mice. Neuron. 1991;6:201-210.
24. McLaughlin SK, Collis P, Hermonat PL, Muzyczka N. Adeno-associated virus general transduction vectors: analysis of proviral structures. J Virol. 1988;62:1963-1973.
25. Qi X, Guy J. Localization of NADPH diaphorase/nitric oxide synthase in the optic nerve of the normal guinea pig: a light and electron microscopic study. J Comp Neurol. 1996;370:396-404.
26. Muzyczka N. Use of adeno-associated virus as a general transduction vector for mammalian cells. Curr Top Microbiol Immunol. 1992:158:97-129.
27. Kaplitt MG, Leone P, Samulski RJ, et al. Long-term gene expression and phenotypic correction using adeno-associated virus vectors in the mammalian brain. Nat Genet. 1994;8:148-154.
28. Guzman RJ, Lemarchand P, Crystal RG, Epstein SE, Finkel T. Efficient and selective adenovirus-mediated gene transfer into vascular neointima. Circulation. 1993;88:2838-2848.
29. Lee SW, Trapnell BC, Rade JJ, Virmani R, Dichek DA. In vivo adenoviral vector-mediated gene transfer into balloon-injured rat carotid arteries. Circ Res. 1993; 73:797-807.
30. Nabel EG, Plautz G, Nabel GJ. Site-specific gene expression in vivo by direct gene transfer into the arterial wall. Science. 1990;249:1285-1288.
31. Russell D, Miller A, Alexander I. Adeno-associated virus vectors preferentially transduce cells in S phase. Proc Natl Acad Sci U S A. 1994;91:8915-8919.
32. Tripathy S, Black H, Goldwasser E, Leiden J. Immune responses to transgene-encoded proteins limit the stability of gene expression after injection of replication-defective adenovirus vectors. Nat Med. 1996;2:545-552.
33. Hoffman LM, Maquire AM, Bennett J. Cell-mediated Immune response and stability of intraocular transgene expression after adenovirus-mediated delivery. Invest Ophthalmol Vis Sci. 1997;38:2224-2233.
34. Xiao X, Li J, Samulski RJ. Efficient long-term gene transfer into muscle tissue of immunocompetent mice by adeno-associated virus vector. J Virol 1996;70: 8098-8108.
35. Kessler PD, Podsakoff GM, Chen X, et al. Gene delivery to skeletal muscle results in sustained expression and systemic delivery of a therapeutic protein. Proc Natl Acad Sci U S A. 1996;93:14082-14087.
36. Guy J, Qi X, Hauswirth WW. Adeno-associated viral-mediated catalase expression suppresses optic neuritis in experimental allergic encephalomyelitis. Proc Natl Acad Sci U S A. 1998;95:13847-13852.