Role of PI 3-kinase, Akt and Bcl-2-related proteins in sustaining the survival of neurotrophic factor-independent adult sympathetic neurons

Journal of Cell Biology

Volumn 154, Issue 5, 2001, Pages 995-1005

  Orike, Nina ^a   Middleton, Gayle ^b   Borthwick, Emma ^b   Buchman, Vladimir ^b   Cowen, Timothy ^a   Davies, Alun M ^b  

^a ROYAL FREE HOSPITAL   (United Kingdom)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

Akt kinase protein kinase B; Bax; BcL xL; Phosphoinositide 3 kinase; Signaling

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; CASPASE; ENZYME INHIBITOR; NEUROTROPHIC FACTOR; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BAD; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL X; PROTEIN KINASE B; WORTMANNIN;

ANIMAL CELL; ARTICLE; CELL SURVIVAL; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; GLIA CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; RAT; SIGNAL TRANSDUCTION; SUPERIOR CERVICAL GANGLION; SYMPATHETIC NERVE;

1-PHOSPHATIDYLINOSITOL 3-KINASE; AMINO ACID CHLOROMETHYL KETONES; ANDROSTADIENES; ANIMALS; APOPTOSIS; CASPASES; CELL SURVIVAL; CELLS, CULTURED; CHROMONES; CULTURE MEDIA, SERUM-FREE; ENZYME INHIBITORS; MICROINJECTIONS; MICROSCOPY, FLUORESCENCE; MORPHOLINES; NEOPLASM PROTEINS; NERVE GROWTH FACTORS; NERVE TISSUE PROTEINS; NEURONS; OLIGODEOXYRIBONUCLEOTIDES, ANTISENSE; PHOSPHORYLATION; PLASMIDS; PROTEIN-SERINE-THREONINE KINASES; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; SUPERIOR CERVICAL GANGLION;

ANIMALIA;

EID: 0035802115     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.200101068     Document Type: Article

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