Effects of neurotrophins on the survival and regrowth of injured retinal neurons

CIBA Foundation Symposia

Volumn , Issue 196, 1996, Pages 135-148

  Aguayo, A J ^a   Clarke, D B ^a   Jelsma, T N ^a   Kittlerova, P ^a   Hyman Friedman, H C ^a   Bray, G M ^a  

^a MONTREAL GENERAL HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

NERVE GROWTH FACTOR;

ANIMAL; APOPTOSIS; CELL DIVISION; CELL SURVIVAL; CYTOLOGY; DRUG EFFECT; NERVE CELL; NERVE FIBER; NERVE REGENERATION; PHYSIOLOGY; RETINA GANGLION CELL; REVIEW;

ANIMALS; APOPTOSIS; AXONS; CELL DIVISION; CELL SURVIVAL; NERVE GROWTH FACTORS; NERVE REGENERATION; NEURONS; RETINAL GANGLION CELLS;

EID: 0030345314     PISSN: 03005208     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (41)

1. Barde Y-A 1989 Trophic factors and neuronal survival. Neuron 2:1525-1534
2. Batistatou A, Greene LA 1991 Aurintricarboxylic acid rescues PC12 cells and sympathetic neurons from cell death caused by nerve growth factor deprivation: correlation with suppression of endonuclease activity. J Cell Biol 115:461-471
3. Berkelaar MJA 1992 Retinal ganglion cell loss after different types of axotomy in the optic nerve. MSc thesis, McGill University, Montreal, Québec, Canada.
4. Berkelaar M, Clarke DB, Wang YC, Bray GM, Aguayo AJ 1994 Axotomy results in delayed death and apoptosis of retinal ganglion cells in adult rats. J Neurosci 14:4368-4374
5. Berkemeier LR, Winslow JW, Kaplan DR, Nikolics K, Goeddel DV, Rosenthal A 1991 Neurotrophin-5: a novel neurotrophic factor that activates trk and trkB. Neuron 7:857-866
6. Bursch W, Kleine L, Tenniswood M 1990 The biochemistry of cell death by apoptosis. Biochem Cell Biol 68:1071-1074
7. Carter DA, Bray GM, Aguayo AJ 1989 Regenerated retinal ganglion cell axons can form well-differentiated synapses in the superior colliculus of adult hamsters. J Neurosci 9:4042-4050
8. Choi DW 1992 Excitotoxic cell death. J Neurobiol 23:1261-1276
9. Clarke DB, Wang Y-C, Bray GM, Aguayo AJ 1994 Endogenous trophic support from the injured eye can enhance survival of axotomized retinal neurons. Soc Neurosci Abstr 20:679
10. Cohen A, Bray GM, Aguayo AJ 1994 Neurotrophin-4/5 (NT-4/5) increases adult rat retinal ganglion cell survival and neurite outgrowth in vitro. J Neurobiol 25:953-959
11. Ebendal T, Olson L, Seiger A, Hedlund KO 1980 Nerve growth factors in the rat iris. Nature 286:25-28
12. Ebendal T, Olson L, Seiger A 1983 The level of nerve growth factor (NGF) as a function of innervation. A correlation radio-immunoassay and bioassay study of the rat iris. Exp Cell Res 148:311-317
13. Faktorovich EG, Steinberg RH, Yasumura D, Matthes MT, LaVail MM 1992 Basic fibroblast growth factor and local injury protect photoreceptors from light damage in the rat. J Neurosci 12:3554-3567
14. Frisen J, Verge VMK, Fried K et al 1993 Characterization of glial trkB receptors: differential response to injury in the central and peripheral nervous systems. Proc Natl Acad Sci USA 90:4971-4975
15. Ghosh A, Carnahan J, Greenberg ME 1994 Requirement for BDNF in activity-dependent survival of cortical neurons. Science 263:1618-1623
16. Harvey AR, Robertson D, Cole KS 1990 Direct visualization of death of neurones projecting to specific targets in the developing rat brain. Exp Brain Res 80:213-217
17. Heumann R, Korsching S, Bandtlow C, Thoenen H 1987 Changes of nerve growth factor synthesis in nonneuronal cells in response to sciatic nerve transection. J Cell Biol 104:1623-1631
18. Ilschner SU, Waring P 1992 Fragmentation of DNA in the retina of chicken enbryos coincides with retinal ganglion cell death. Biochem Biophys Res Commun 183: 1056-1061
19. Ip NY, Ibanez CF, Nye SH et al 1992 Mammalian neurotrophin-4: structure, chromosomal localization, tissue distribution, and receptor specificity. Proc Natl Acad Sci USA 89:3060-3064
20. Jelsma TN, Friedman HH, Berkelaar M, Bray GM, Aguayo AJ 1993 Different forms of the neurotrophin receptor trkB mRNA predominate in rat retina and optic nerve. J Neurobiol 24:1207-1214
21. Jelsma TN, Hyman Friedman C, Wang Y-C, Dunn RJ, Bray GM, Aguayo AJ 1994 Effects of optic nerve lesions on neurotrophin and neurotrophin receptor mRNA in the adult rat optic nerve. Soc Neurosci Abstr 20:42
22. Johnson EM Jr, Deckwerth TL 1993 Molecular mechanisms of developmental neuronal death. Ann Rev Neurosci 16:31-46
23. Kittlerova P, Playford DE, Bray GM, Aguayo AJ 1994 NT-3 enhances growth and upregulates GAP43 in a subset of retinal ganglion cells after axotomy. Soc Neurosci Abstr 20:1098
24. Klein R, Nanduri V, Jing SA et al 1991 The trkB tyrosine protein kinase is a receptor for brain-derived neurotrophic factor and neurotrophin-3. Cell 66:395-403
25. Lu B, Yokoyama M, Dreyfus CF, Black IB 1991 NGF gene expression in actively growing brain glia. J Neurosci 11:318-326
26. Luo Y, Raper JA 1994 Inhibitory factors controlling growth cone motility and guidance. Curr Opin Neurobiol 4:648-654
27. Mansour-Robaey S, Clarke DB, Wang YC, Bray GM, Aguayo AJ 1994 Effects of ocular injury and administration of brain-derived neurotrophic factor on survival and regrowth of axotomized retinal ganglion cells. Proc Natl Acad Sci USA 91:1632-1636
28. Martin DP, Schmidt RE, DiStefano PS, Lowry OH, Carter JG, Johnson EM Jr 1988 Inhibitors of protein synthesis and RNA synthesis prevent neuronal death caused by nerve growth factor deprivation. J Cell Biol 106:829-844
29. McKerracher L, Vidal-Sanz M, Essagian C, Aguayo AJ 1990 Selective impairment of slow axonal transport after optic nerve injury in adult rats. J Neurosci 10:2834-2841
30. McKerracher L, Essagian C, Aguayo AJ 1993 Marked increase in beta-tubulin mRNA expression during regeneration of axotomized retinal ganglion cells in adult mammals. J Neurosci 13:5294-5300
31. Meyer M, Matsuoka I, Wetmore C, Olson L, Thoenen H 1992 Enhanced synthesis of brain-derived neurotrophic factor in the lesioned peripheral nerve: different mechanisms are responsible for the regulation of BDNF and NGF mRNA. J Cell Biol 119:45-54
32. Perez MT, Caminos E 1995 Expression of brain-derived neurotrophic factor and of its functional receptor in neonatal and adult rat retina. Neurosci Lett 183:96-99
33. Rabacchi SA, Ensini M, Bonfanti L, Gravina A, Maffei L 1994 Nerve growth factor reduces apoptosis of axotomized retinal ganglion cells in the neonatal rat. Neuroscience 63:969-973
34. Schnell L, Schneider R, Kolbeck R, Barde YA, Schwab ME 1994 Neurotrophin-3 enhances sprouting of corticospinal tract during development and after adult spinal cord lesion. Nature 367:170-173
35. Schwab ME 1993 Experimental aspects of spinal cord regeneration. Curr Opin Neurol Neurosurg 6:549-553
36. Shelton DL, Reichardt LF 1986 Studies on the regulation of beta-nerve growth factor gene expression in the rat iris: the level of mRNA encoding nerve growth factor is increased in irises placed in explant cultures in vitro, but not in irises deprived of sensory or sympathetic innervation in vivo. J Cell Biol 102:1940-1948
37. Snider WD, Elliott JL, Yan Q 1993 Axotomy-induced neuronal death during development. J Neurobiol 23:1231-1246
38. Squinto SP, Stitt TN, Aldrich TH et al 1991 trkB encodes a functional receptor for brain-derived neurotrophic factor and neurotrophin-3 but not nerve growth factor. Cell 65:885-893
39. Vidal-Sanz M, Bray GM, Villegas-Perez MP, Thanos S, Aguayo AJ 1987 Axonal regeneration and synapse formation in the superior colliculus by retinal ganglion cells in the adult rat. J Neurosci 7:2894-2909
40. Vidal-Sanz M, Bray GM, Aguayo AJ 1991 Regenerated synapses persist in the superior colliculus after the regrowth of retinal ganglion cell axons. J Neurocytol 20:940-952
41. Villegas-Perez MP, Vidal-Sanz M, Bray GM, Aguayo AJ 1988 Influences of peripheral nerve grafts on the survival and regrowth of axotomized retinal ganglion cells in adult rats. J Neurosci 8:265-280